Project
2D miR_HR1_12
Navigation
Downloads
Results for Stat5a
Z-value: 1.97
Motif logo
Transcription factors associated with Stat5a
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Stat5a | mm10_v2_chr11_+_100860326_100860345 | -0.26 | 4.1e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr6_-_78468863 Show fit | 5.27 |
ENSMUST00000032089.2
|
regenerating islet-derived 3 gamma |
|
| chr6_+_78370877 Show fit | 5.19 |
ENSMUST00000096904.3
|
regenerating islet-derived 3 beta |
|
| chr11_+_69964758 Show fit | 4.17 |
ENSMUST00000108597.1
ENSMUST00000060651.5 ENSMUST00000108596.1 |
claudin 7 |
|
| chr6_-_41377604 Show fit | 3.72 |
ENSMUST00000096003.5
|
protease, serine, 3 |
|
| chr6_+_78380700 Show fit | 3.63 |
ENSMUST00000101272.1
|
regenerating islet-derived 3 alpha |
|
| chr7_+_43995833 Show fit | 3.53 |
ENSMUST00000007156.4
|
kallikrein 1-related peptidase b11 |
|
| chr9_+_107296843 Show fit | 3.23 |
ENSMUST00000167072.1
|
cytokine inducible SH2-containing protein |
|
| chr5_-_108795352 Show fit | 3.08 |
ENSMUST00000004943.1
|
transmembrane emp24 protein transport domain containing |
|
| chr10_+_87521795 Show fit | 2.84 |
ENSMUST00000020241.8
|
phenylalanine hydroxylase |
|
| chr6_+_41354105 Show fit | 2.79 |
ENSMUST00000072103.5
|
trypsin 10 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Stat5a
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 9.7 | GO:0007586 | digestion(GO:0007586) |
| 0.5 | 9.4 | GO:0032463 | negative regulation of protein homooligomerization(GO:0032463) |
| 0.2 | 7.5 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.2 | 7.2 | GO:0006953 | acute-phase response(GO:0006953) |
| 2.3 | 7.0 | GO:0006571 | tyrosine biosynthetic process(GO:0006571) aromatic amino acid family biosynthetic process(GO:0009073) aromatic amino acid family biosynthetic process, prephenate pathway(GO:0009095) |
| 0.9 | 5.5 | GO:0051715 | cytolysis in other organism(GO:0051715) |
| 0.6 | 5.2 | GO:1903208 | neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208) |
| 0.2 | 4.8 | GO:0046688 | response to copper ion(GO:0046688) |
| 0.0 | 3.9 | GO:0010466 | negative regulation of peptidase activity(GO:0010466) |
| 0.4 | 3.6 | GO:0045617 | negative regulation of keratinocyte differentiation(GO:0045617) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 52.4 | GO:0005615 | extracellular space(GO:0005615) |
| 0.3 | 8.3 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.1 | 7.9 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.3 | 7.4 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.2 | 5.9 | GO:0034364 | high-density lipoprotein particle(GO:0034364) |
| 0.2 | 5.9 | GO:0044216 | other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217) |
| 0.1 | 4.8 | GO:0046658 | anchored component of plasma membrane(GO:0046658) |
| 0.0 | 3.2 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.0 | 2.8 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 2.7 | GO:0005811 | lipid particle(GO:0005811) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 36.2 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.1 | 13.1 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 1.3 | 6.7 | GO:0004505 | phenylalanine 4-monooxygenase activity(GO:0004505) |
| 0.1 | 6.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.5 | 5.5 | GO:0042834 | peptidoglycan binding(GO:0042834) |
| 0.0 | 4.9 | GO:0004860 | protein kinase inhibitor activity(GO:0004860) |
| 0.1 | 4.7 | GO:0015020 | glucuronosyltransferase activity(GO:0015020) |
| 0.1 | 4.2 | GO:0008009 | chemokine activity(GO:0008009) |
| 0.2 | 3.9 | GO:0005540 | hyaluronic acid binding(GO:0005540) |
| 0.5 | 3.8 | GO:0004322 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 17.7 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 11.6 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.0 | 9.5 | NABA SECRETED FACTORS | Genes encoding secreted soluble factors |
| 0.7 | 7.2 | ST INTERFERON GAMMA PATHWAY | Interferon gamma pathway. |
| 0.1 | 7.2 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
| 0.1 | 4.7 | PID IL4 2PATHWAY | IL4-mediated signaling events |
| 0.0 | 2.7 | PID HIF1 TFPATHWAY | HIF-1-alpha transcription factor network |
| 0.0 | 2.7 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 2.3 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.1 | 1.4 | PID SYNDECAN 4 PATHWAY | Syndecan-4-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 9.5 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.2 | 8.4 | REACTOME GROWTH HORMONE RECEPTOR SIGNALING | Genes involved in Growth hormone receptor signaling |
| 0.1 | 5.0 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 4.2 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |
| 0.0 | 3.5 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.1 | 3.1 | REACTOME GLUTATHIONE CONJUGATION | Genes involved in Glutathione conjugation |
| 0.2 | 3.0 | REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON | Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon |
| 0.0 | 3.0 | REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES | Genes involved in Metabolism of amino acids and derivatives |
| 0.0 | 2.9 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 2.6 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |