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avrg: GFI1 WT vs 36n/n vs KD

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Results for Pou2f2_Pou3f1

Z-value: 7.07

Motif logo

Transcription factors associated with Pou2f2_Pou3f1

Gene Symbol Gene ID Gene Info
ENSMUSG00000008496.20 POU domain, class 2, transcription factor 2
ENSMUSG00000090125.4 POU domain, class 3, transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou3f1mm39_v1_chr4_+_124550600_1245506000.951.2e-02Click!
Pou2f2mm39_v1_chr7_-_24831892_248319370.622.7e-01Click!

Activity profile of Pou2f2_Pou3f1 motif

Sorted Z-values of Pou2f2_Pou3f1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_23930717 38.78 ENSMUST00000099703.5
H2B clustered histone 3
chr13_-_23758370 20.98 ENSMUST00000105106.2
H2B clustered histone 7
chr3_-_96128196 20.35 ENSMUST00000090782.4
H2A clustered histone 20
chr3_+_96177010 19.31 ENSMUST00000051089.4
ENSMUST00000177113.2
predicted gene 42743
H2B clustered histone 18
chr13_+_23868175 19.02 ENSMUST00000018246.6
H2B clustered histone 4
chr13_+_22220000 18.13 ENSMUST00000110455.4
H2B clustered histone 12
chr3_+_96152813 18.07 ENSMUST00000078756.7
ENSMUST00000090779.4
H2A clustered histone 18
predicted gene 20634
chr13_+_21906214 17.73 ENSMUST00000224651.2
H2B clustered histone 14
chr13_+_22227359 17.63 ENSMUST00000110452.2
H2B clustered histone 11
chr3_-_96147592 17.39 ENSMUST00000074976.8
H2A clustered histone 19
chr13_+_23755551 14.80 ENSMUST00000079251.8
H2B clustered histone 8
chr13_+_23728222 14.70 ENSMUST00000075558.5
H3 clustered histone 7
chr13_-_23867924 14.08 ENSMUST00000171127.4
H2A clustered histone 6
chr13_+_23935088 13.00 ENSMUST00000078369.3
H2A clustered histone 4
chr13_-_24118139 12.46 ENSMUST00000052776.4
H2B clustered histone 1
chr13_-_23755374 11.25 ENSMUST00000102969.6
H2A clustered histone 8
chr13_-_21994366 10.33 ENSMUST00000091749.4
H2B clustered histone 23
chr11_+_58845502 10.33 ENSMUST00000108817.5
ENSMUST00000047697.12
H2A.W histone
tripartite motif-containing 17
chr13_-_23805077 8.80 ENSMUST00000091704.7
ENSMUST00000051091.5
H2B clustered histone 6
chr13_+_22017906 8.71 ENSMUST00000180288.2
H2B clustered histone 24
chr13_-_22219738 8.65 ENSMUST00000091742.6
H2A clustered histone 12
chr13_-_22227114 8.59 ENSMUST00000091741.6
H2A clustered histone 11
chr13_+_21971631 8.02 ENSMUST00000110473.3
ENSMUST00000102982.2
H2B clustered histone 22
chr13_+_23718038 7.24 ENSMUST00000073261.3
H2A clustered histone 10
chr13_+_21994588 6.43 ENSMUST00000091745.6
H2A clustered histone 23
chr13_+_23758555 6.16 ENSMUST00000090776.7
H2A clustered histone 7
chr11_+_58839716 5.90 ENSMUST00000078267.5
H2B.U histone 2
chr7_+_44667377 5.77 ENSMUST00000044111.10
related RAS viral (r-ras) oncogene
chr6_+_136495818 5.59 ENSMUST00000186577.7
activating transcription factor 7 interacting protein
chr9_+_106099797 5.11 ENSMUST00000062241.11
toll-like receptor 9
chr8_+_69333143 4.89 ENSMUST00000015712.15
lipoprotein lipase
chr8_+_109441276 4.63 ENSMUST00000043896.10
zinc finger homeobox 3
chr14_-_67106037 4.32 ENSMUST00000022629.9
dihydropyrimidinase-like 2
chr2_-_18053595 4.27 ENSMUST00000142856.2
SKI/DACH domain containing 1
chr13_-_21971388 4.21 ENSMUST00000091751.3
H2A clustered histone 22
chr17_-_35383867 4.06 ENSMUST00000025253.12
proline-rich coiled-coil 2A
chr13_-_22017677 3.99 ENSMUST00000081342.7
H2A clustered histone 24
chr6_+_136495784 3.94 ENSMUST00000032335.13
ENSMUST00000185724.7
activating transcription factor 7 interacting protein
chr15_+_6552270 3.82 ENSMUST00000226412.2
FYN binding protein
chr8_+_91635192 3.51 ENSMUST00000211403.2
chromodomain helicase DNA binding protein 9
chr11_+_34264757 3.43 ENSMUST00000165963.9
ENSMUST00000093192.4
inhibitory synaptic factor family member 2B
chr3_+_96127174 3.18 ENSMUST00000073115.5
H2A clustered histone 21
chr5_+_42225303 3.15 ENSMUST00000087332.5
predicted gene 16223
chr9_-_51076724 3.12 ENSMUST00000210433.2
predicted gene, 32742
chr8_+_108669276 3.04 ENSMUST00000220518.2
zinc finger homeobox 3
chr10_-_12745109 2.88 ENSMUST00000218635.2
utrophin
chr16_-_4698148 2.82 ENSMUST00000037843.7
UBA-like domain containing 1
chr5_+_105879914 2.70 ENSMUST00000154807.2
leucine rich repeat containing 8D
chr13_+_41071077 2.51 ENSMUST00000067778.8
ENSMUST00000225759.2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr4_-_128699838 2.45 ENSMUST00000106072.9
ENSMUST00000170934.3
zinc finger protein 362
chrX_-_165992311 2.39 ENSMUST00000112172.4
thymosin, beta 4, X chromosome
chr16_-_92494203 2.39 ENSMUST00000113956.10
runt related transcription factor 1
chr12_-_114752425 2.22 ENSMUST00000103510.2
immunoglobulin heavy variable 1-26
chr13_-_40887244 2.18 ENSMUST00000110193.9
transcription factor AP-2, alpha
chr11_-_110142565 2.07 ENSMUST00000044003.14
ATP-binding cassette, sub-family A (ABC1), member 6
chr16_-_92622972 1.90 ENSMUST00000023673.14
runt related transcription factor 1
chr7_+_126376099 1.89 ENSMUST00000038614.12
ENSMUST00000170882.8
ENSMUST00000106359.2
ENSMUST00000106357.8
ENSMUST00000145762.8
yippee like 3
chr10_+_66932235 1.87 ENSMUST00000174317.8
jumonji domain containing 1C
chrX_-_16777913 1.75 ENSMUST00000040134.8
Norrie disease (pseudoglioma) (human)
chr13_-_95661726 1.73 ENSMUST00000022185.10
coagulation factor II (thrombin) receptor-like 1
chr13_-_108026590 1.66 ENSMUST00000225822.4
ENSMUST00000225197.3
zinc finger SWIM-type containing 6
chr9_-_85209340 1.65 ENSMUST00000187711.2
terminal nucleotidyltransferase 5A
chr7_+_24981604 1.62 ENSMUST00000163320.8
ENSMUST00000005578.13
capicua transcriptional repressor
chr6_-_99073156 1.62 ENSMUST00000175886.8
forkhead box P1
chr10_+_128542120 1.61 ENSMUST00000054125.9
premelanosome protein
chr11_-_23720953 1.51 ENSMUST00000102864.5
reticuloendotheliosis oncogene
chr2_+_118877610 1.49 ENSMUST00000153300.8
ENSMUST00000028799.12
kinetochore scaffold 1
chr5_+_135135735 1.41 ENSMUST00000201977.4
ENSMUST00000005507.10
MLX interacting protein-like
chr9_-_85209162 1.40 ENSMUST00000034802.15
terminal nucleotidyltransferase 5A
chr13_+_16186410 1.38 ENSMUST00000042603.14
inhibin beta-A
chr11_-_5787743 1.37 ENSMUST00000109837.8
polymerase (DNA directed), mu
chr9_+_75682637 1.33 ENSMUST00000012281.8
bone morphogenetic protein 5
chr11_+_6339061 1.32 ENSMUST00000109787.8
zinc finger, MIZ-type containing 2
chr2_-_30364219 1.31 ENSMUST00000065134.4
immediate early response 5-like
chr1_-_66856695 1.30 ENSMUST00000068168.10
ENSMUST00000113987.2
KAT8 regulatory NSL complex subunit 1-like
chr18_-_60724855 1.30 ENSMUST00000056533.9
myozenin 3
chr2_+_90927053 1.30 ENSMUST00000132741.3
spleen focus forming virus (SFFV) proviral integration oncogene
chr5_+_53747796 1.30 ENSMUST00000113865.5
recombination signal binding protein for immunoglobulin kappa J region
chr19_-_40260060 1.29 ENSMUST00000068439.13
PDZ and LIM domain 1 (elfin)
chr6_+_67586695 1.24 ENSMUST00000103303.3
immunoglobulin kappa variable 1-135
chr11_+_115272732 1.10 ENSMUST00000053288.6
cerebellar degeneration-related protein 2-like
chr19_+_53128901 1.09 ENSMUST00000235754.2
ENSMUST00000237301.2
ENSMUST00000238130.2
adducin 3 (gamma)
chr4_-_152561896 1.07 ENSMUST00000238738.2
ENSMUST00000162017.3
ENSMUST00000030768.10
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr5_-_135518098 1.06 ENSMUST00000201998.2
huntingtin interacting protein 1
chr2_-_35995283 1.06 ENSMUST00000112960.8
ENSMUST00000112967.12
ENSMUST00000112963.8
LIM homeobox protein 6
chr8_+_121215155 1.00 ENSMUST00000034279.16
genetic suppressor element 1, coiled-coil protein
chr4_-_129590372 1.00 ENSMUST00000137640.3
transmembrane protein 39b
chr7_+_18962301 0.98 ENSMUST00000161711.2
optic atrophy 3
chr11_+_6339442 0.97 ENSMUST00000109786.8
zinc finger, MIZ-type containing 2
chr7_+_121888520 0.93 ENSMUST00000064989.12
ENSMUST00000064921.5
protein kinase C, beta
chr17_+_47451868 0.92 ENSMUST00000190080.9
transcriptional regulating factor 1
chr11_+_6339330 0.92 ENSMUST00000012612.11
zinc finger, MIZ-type containing 2
chr13_+_37529184 0.91 ENSMUST00000021860.7
lymphocyte antigen 86
chr9_+_77959206 0.91 ENSMUST00000024104.9
glial cells missing homolog 1
chr10_-_12490424 0.90 ENSMUST00000217994.2
utrophin
chr5_-_124003553 0.90 ENSMUST00000057145.7
hydroxycarboxylic acid receptor 2
chr2_+_118877594 0.88 ENSMUST00000152380.8
ENSMUST00000099542.9
kinetochore scaffold 1
chr13_+_102830029 0.88 ENSMUST00000022124.10
ENSMUST00000171267.2
ENSMUST00000167144.2
ENSMUST00000170878.2
CD180 antigen
chr5_-_21906330 0.86 ENSMUST00000115217.8
ENSMUST00000060899.9
N-acyl phosphatidylethanolamine phospholipase D
chr7_-_102507962 0.82 ENSMUST00000213481.2
ENSMUST00000209952.2
olfactory receptor 566
chr6_+_68402550 0.81 ENSMUST00000103323.3
immunoglobulin kappa variable 16-104
chr7_-_28071919 0.80 ENSMUST00000119990.8
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr16_+_42727926 0.80 ENSMUST00000151244.8
ENSMUST00000114694.9
zinc finger and BTB domain containing 20
chr2_-_63928339 0.79 ENSMUST00000131615.9
fidgetin
chr16_+_44913974 0.78 ENSMUST00000099498.10
coiled-coil domain containing 80
chr12_-_114710326 0.78 ENSMUST00000103507.2
immunoglobulin heavy variable 1-22
chr12_+_55211069 0.76 ENSMUST00000218889.2
signal recognition particle 54B
chr12_-_114502585 0.76 ENSMUST00000103496.4
immunoglobulin heavy variable V1-7
chr7_+_140774962 0.75 ENSMUST00000047093.11
leucine rich repeat containing 56
chr19_-_40260286 0.75 ENSMUST00000182432.2
PDZ and LIM domain 1 (elfin)
chr19_+_53128861 0.75 ENSMUST00000111741.10
adducin 3 (gamma)
chr12_-_114451189 0.74 ENSMUST00000103493.3
immunoglobulin heavy variable 1-4
chr10_+_67373691 0.73 ENSMUST00000048289.14
ENSMUST00000130933.2
ENSMUST00000105438.9
ENSMUST00000146986.2
early growth response 2
chr12_-_113625906 0.73 ENSMUST00000103448.3
immunoglobulin heavy variable 5-9
chr13_+_102830104 0.70 ENSMUST00000172138.2
CD180 antigen
chr11_+_69217078 0.70 ENSMUST00000018614.3
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr8_+_71069476 0.69 ENSMUST00000052437.6
leucine rich repeat containing 25
chr3_-_144525255 0.67 ENSMUST00000029929.12
chloride channel accessory 3A2
chr13_+_83723255 0.67 ENSMUST00000199167.5
ENSMUST00000195904.5
myocyte enhancer factor 2C
chr7_+_92390811 0.66 ENSMUST00000032879.15
RAB30, member RAS oncogene family
chr5_+_123153072 0.66 ENSMUST00000051016.5
ENSMUST00000121652.8
ORAI calcium release-activated calcium modulator 1
chr5_+_53747556 0.65 ENSMUST00000037618.13
ENSMUST00000201912.4
recombination signal binding protein for immunoglobulin kappa J region
chr2_+_164664920 0.65 ENSMUST00000132282.2
zinc finger SWIM-type containing 1
chr1_+_93163553 0.65 ENSMUST00000062202.14
sushi, nidogen and EGF-like domains 1
chr2_-_57942844 0.64 ENSMUST00000090940.6
ermin, ERM-like protein
chr8_+_71151581 0.63 ENSMUST00000095267.8
jun D proto-oncogene
chr18_+_20509771 0.63 ENSMUST00000076737.7
desmoglein 1 beta
chr2_-_32977182 0.61 ENSMUST00000102810.10
GTPase activating RANGAP domain-like 3
chr6_+_68279392 0.60 ENSMUST00000103322.3
immunoglobulin kappa variable 2-109
chrX_-_73129195 0.60 ENSMUST00000140399.3
ENSMUST00000123362.8
ENSMUST00000100750.10
ENSMUST00000033770.13
methyl CpG binding protein 2
chr3_-_80710097 0.60 ENSMUST00000075316.10
ENSMUST00000107745.8
glutamate receptor, ionotropic, AMPA2 (alpha 2)
chr9_+_65831489 0.57 ENSMUST00000130798.3
casein kinase 1, gamma 1
chr12_-_115916604 0.56 ENSMUST00000196991.2
immunoglobulin heavy variable 1-82
chr15_+_57558048 0.56 ENSMUST00000096430.11
zinc fingers and homeoboxes 2
chr17_-_24752683 0.56 ENSMUST00000061764.14
RAB26, member RAS oncogene family
chr4_-_123458465 0.56 ENSMUST00000238731.2
microtubule-actin crosslinking factor 1
chr12_-_56583582 0.55 ENSMUST00000001536.9
NK2 homeobox 1
chr1_-_163141230 0.54 ENSMUST00000174397.3
ENSMUST00000075805.13
paired related homeobox 1
chrX_+_7744535 0.53 ENSMUST00000033495.15
proviral integration site 2
chr6_+_70675416 0.52 ENSMUST00000103403.3
immunoglobulin kappa variable 3-2
chr16_-_89615225 0.52 ENSMUST00000164263.9
T cell lymphoma invasion and metastasis 1
chr6_-_72498676 0.51 ENSMUST00000234615.2
SH2 domain containing 6
chr12_-_114443071 0.50 ENSMUST00000103492.2
immunoglobulin heavy variable 10-1
chr7_-_44702269 0.46 ENSMUST00000057293.8
proline rich 12
chr2_-_26393826 0.46 ENSMUST00000028288.5
notch 1
chr13_+_38529062 0.45 ENSMUST00000171970.3
bone morphogenetic protein 6
chr17_+_27775471 0.45 ENSMUST00000118599.9
ENSMUST00000232265.2
ENSMUST00000232013.2
ENSMUST00000114888.11
ENSMUST00000231874.2
ENSMUST00000119486.9
ENSMUST00000231825.2
ENSMUST00000231866.2
high mobility group AT-hook 1
chr14_-_103220066 0.45 ENSMUST00000184744.2
potassium channel tetramerisation domain containing 12
chr11_+_60360165 0.45 ENSMUST00000071880.9
ENSMUST00000081823.12
ENSMUST00000094135.9
myosin XV
chr7_+_5018453 0.45 ENSMUST00000086349.5
ENSMUST00000207050.2
zinc finger protein 524
predicted gene 44973
chr5_-_5315968 0.44 ENSMUST00000115451.8
ENSMUST00000115452.8
ENSMUST00000131392.8
cyclin-dependent kinase 14
chr18_+_69654572 0.44 ENSMUST00000200862.4
transcription factor 4
chr2_-_25982160 0.44 ENSMUST00000114159.9
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr10_-_129751466 0.43 ENSMUST00000213438.2
olfactory receptor 816
chr10_+_79763164 0.43 ENSMUST00000105376.2
AT rich interactive domain 3A (BRIGHT-like)
chr12_-_17374704 0.42 ENSMUST00000020884.16
ENSMUST00000095820.12
ENSMUST00000221129.2
ENSMUST00000127185.8
ATPase, H+ transporting, lysosomal V1 subunit C2
chr11_+_108814007 0.42 ENSMUST00000106711.2
axin 2
chr2_-_168048984 0.42 ENSMUST00000088001.6
activity-dependent neuroprotective protein
chr1_-_163141278 0.41 ENSMUST00000027878.14
paired related homeobox 1
chr4_+_97660971 0.41 ENSMUST00000152023.8
nuclear factor I/A
chr5_-_86475595 0.40 ENSMUST00000122377.2
transmembrane protease, serine 11d
chr7_-_28072022 0.40 ENSMUST00000144700.8
pleckstrin homology domain containing, family G (with RhoGef domain) member 2
chr1_-_14380418 0.37 ENSMUST00000027066.13
ENSMUST00000168081.9
EYA transcriptional coactivator and phosphatase 1
chr12_-_115832846 0.35 ENSMUST00000199373.2
immunoglobulin heavy variable 1-78
chr16_+_91526169 0.34 ENSMUST00000114001.8
ENSMUST00000113999.8
ENSMUST00000064797.12
ENSMUST00000114002.9
ENSMUST00000095909.10
ENSMUST00000056482.14
ENSMUST00000113996.8
intersectin 1 (SH3 domain protein 1A)
chr6_+_68414401 0.34 ENSMUST00000103324.3
immunoglobulin kappa chain variable 15-103
chr10_-_81186137 0.34 ENSMUST00000167481.8
high mobility group 20B
chr17_-_27352876 0.34 ENSMUST00000119227.3
ENSMUST00000025045.15
ubiquinol-cytochrome c reductase complex assembly factor 2
chr6_-_87510200 0.33 ENSMUST00000113637.9
ENSMUST00000071024.7
Rho GTPase activating protein 25
chr12_-_115884332 0.33 ENSMUST00000103548.3
immunoglobulin heavy variable 1-81
chr12_-_114878652 0.32 ENSMUST00000103515.2
immunoglobulin heavy variable 1-39
chr3_+_96128427 0.32 ENSMUST00000090781.8
H2B clustered histone 21
chr6_-_52181393 0.30 ENSMUST00000048794.7
homeobox A5
chr8_+_23464860 0.30 ENSMUST00000110688.9
ENSMUST00000121802.9
ankyrin 1, erythroid
chr3_+_159201092 0.29 ENSMUST00000106041.3
DEP domain containing 1a
chr7_-_44646960 0.28 ENSMUST00000207443.2
ENSMUST00000207755.2
ENSMUST00000003290.12
BCL2-like 12 (proline rich)
chr6_+_67532481 0.27 ENSMUST00000103302.3
immunoglobulin kappa chain variable 2-137
chr16_-_92622659 0.27 ENSMUST00000186296.2
runt related transcription factor 1
chr6_+_70640233 0.27 ENSMUST00000103400.3
immunoglobulin kappa chain variable 3-5
chr2_-_160950936 0.26 ENSMUST00000039782.14
ENSMUST00000134178.8
chromodomain helicase DNA binding protein 6
chr6_+_92069376 0.26 ENSMUST00000113463.8
nuclear receptor subfamily 2, group C, member 2
chr9_+_59485475 0.26 ENSMUST00000118549.8
ENSMUST00000034840.10
CUGBP, Elav-like family member 6
chr10_-_81186222 0.26 ENSMUST00000020454.11
ENSMUST00000105324.9
ENSMUST00000154609.3
ENSMUST00000105323.8
high mobility group 20B
chr1_-_91386976 0.25 ENSMUST00000069620.10
period circadian clock 2
chr11_-_118977047 0.25 ENSMUST00000026665.8
chromobox 4
chr6_-_30693675 0.25 ENSMUST00000169422.8
ENSMUST00000115131.8
ENSMUST00000115130.3
ENSMUST00000031810.15
centrosomal protein 41
chr10_+_79762858 0.24 ENSMUST00000019708.12
ENSMUST00000105377.8
AT rich interactive domain 3A (BRIGHT-like)
chr13_-_46118433 0.24 ENSMUST00000167708.4
ENSMUST00000091628.11
ENSMUST00000180110.9
ataxin 1
chr4_+_3678108 0.24 ENSMUST00000041377.13
ENSMUST00000103010.4
LYN proto-oncogene, Src family tyrosine kinase
chr7_+_120581719 0.24 ENSMUST00000033166.10
major facilitator superfamily domain containing 13B
chr14_-_20784625 0.24 ENSMUST00000223679.2
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr7_+_126376353 0.23 ENSMUST00000106356.2
yippee like 3
chr12_-_114843941 0.23 ENSMUST00000191862.6
ENSMUST00000103513.3
immunoglobulin heavy variable 1-36
chr11_-_30148230 0.22 ENSMUST00000102838.10
spectrin beta, non-erythrocytic 1
chr18_-_79152504 0.22 ENSMUST00000025430.11
SET binding protein 1
chr12_-_113589576 0.21 ENSMUST00000103446.2
immunoglobulin heavy variable 5-6
chr12_-_114023935 0.21 ENSMUST00000103469.4
immunoglobulin heavy variable V14-3
chr12_-_115109539 0.21 ENSMUST00000192554.6
ENSMUST00000103522.3
immunoglobulin heavy variable 1-52
chr5_-_46014809 0.20 ENSMUST00000190036.7
ENSMUST00000189859.7
ENSMUST00000186633.3
ENSMUST00000016026.14
ENSMUST00000045586.13
ENSMUST00000238522.2
ligand dependent nuclear receptor corepressor-like
chr9_+_31191820 0.19 ENSMUST00000117389.8
ENSMUST00000215499.2
PR domain containing 10

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou2f2_Pou3f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.1 GO:0032741 positive regulation of interleukin-18 production(GO:0032741)
1.5 7.7 GO:1904059 regulation of locomotor rhythm(GO:1904059)
1.1 4.6 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.7 4.9 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.6 1.7 GO:1900135 positive regulation of eosinophil degranulation(GO:0043311) regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949) positive regulation of renin secretion into blood stream(GO:1900135) positive regulation of eosinophil activation(GO:1902568)
0.5 3.8 GO:0007527 adult somatic muscle development(GO:0007527)
0.4 2.2 GO:0003409 optic cup structural organization(GO:0003409)
0.4 0.9 GO:1903999 negative regulation of eating behavior(GO:1903999)
0.4 2.0 GO:1901297 positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.4 2.5 GO:0036438 maintenance of lens transparency(GO:0036438)
0.3 1.4 GO:0042701 progesterone secretion(GO:0042701)
0.3 1.3 GO:0021502 neural fold elevation formation(GO:0021502)
0.3 0.3 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.3 1.1 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.3 0.8 GO:0021660 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.3 1.3 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.3 1.8 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.2 2.9 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.2 2.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.2 0.5 GO:0061344 regulation of cell adhesion involved in heart morphogenesis(GO:0061344) positive regulation of ephrin receptor signaling pathway(GO:1901189)
0.2 0.9 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 1.4 GO:0090324 negative regulation of oxidative phosphorylation(GO:0090324)
0.2 0.6 GO:0071317 cellular response to isoquinoline alkaloid(GO:0071317) negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.2 1.5 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.2 0.5 GO:0021759 globus pallidus development(GO:0021759)
0.2 1.6 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.2 0.5 GO:1904266 regulation of Schwann cell chemotaxis(GO:1904266) positive regulation of Schwann cell chemotaxis(GO:1904268) Schwann cell chemotaxis(GO:1990751)
0.2 1.9 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.2 1.0 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.2 4.3 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.1 2.5 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 0.4 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.1 10.3 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 1.9 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.9 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 0.9 GO:0070162 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163)
0.1 1.6 GO:1900378 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.1 1.6 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.1 2.8 GO:0045898 regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045898)
0.1 0.1 GO:1904172 positive regulation of bleb assembly(GO:1904172)
0.1 0.3 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.1 0.2 GO:0034136 negative regulation of toll-like receptor 2 signaling pathway(GO:0034136) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.3 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.1 0.9 GO:0048664 neuron fate determination(GO:0048664)
0.1 1.1 GO:0070995 NADPH oxidation(GO:0070995)
0.1 0.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.1 0.7 GO:2000111 primary heart field specification(GO:0003138) sinoatrial valve development(GO:0003172) sinoatrial valve morphogenesis(GO:0003185) positive regulation of macrophage apoptotic process(GO:2000111)
0.0 0.3 GO:2000054 regulation of mismatch repair(GO:0032423) regulation of chondrocyte development(GO:0061181) negative regulation of Wnt signaling pathway involved in dorsal/ventral axis specification(GO:2000054)
0.0 0.0 GO:0060853 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101)
0.0 3.1 GO:0060325 face morphogenesis(GO:0060325)
0.0 3.8 GO:0045576 mast cell activation(GO:0045576)
0.0 0.7 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.3 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551)
0.0 0.6 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.7 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 0.1 GO:0009624 response to nematode(GO:0009624)
0.0 0.8 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.3 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.6 GO:0002076 osteoblast development(GO:0002076)
0.0 0.2 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.1 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.1 GO:0036343 psychomotor behavior(GO:0036343)
0.0 0.2 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0 1.5 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.8 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 0.2 GO:0060736 prostate gland growth(GO:0060736)
0.0 0.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 1.4 GO:2001222 regulation of neuron migration(GO:2001222)
0.0 0.2 GO:0060573 ventral spinal cord interneuron specification(GO:0021521) cell fate specification involved in pattern specification(GO:0060573)
0.0 0.0 GO:0006553 lysine metabolic process(GO:0006553)
0.0 0.6 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.1 GO:0014807 regulation of somitogenesis(GO:0014807)
0.0 0.4 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.2 GO:0006851 mitochondrial calcium ion transport(GO:0006851)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 5.1 GO:0036019 endolysosome(GO:0036019)
0.5 1.4 GO:0043512 inhibin A complex(GO:0043512)
0.4 1.1 GO:1990031 pinceau fiber(GO:1990031)
0.3 2.4 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.2 4.9 GO:0042627 chylomicron(GO:0042627)
0.2 1.1 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.2 0.7 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.2 1.6 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 3.9 GO:0070938 contractile ring(GO:0070938)
0.1 0.6 GO:0035976 AP1 complex(GO:0035976)
0.1 1.5 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 0.4 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.1 0.6 GO:0033269 internode region of axon(GO:0033269)
0.1 0.4 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 0.8 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.1 1.7 GO:0031143 pseudopodium(GO:0031143)
0.1 0.2 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.0 1.9 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.2 GO:0032437 cuticular plate(GO:0032437)
0.0 0.5 GO:0060091 kinocilium(GO:0060091)
0.0 5.3 GO:0005604 basement membrane(GO:0005604)
0.0 1.8 GO:0043596 nuclear replication fork(GO:0043596)
0.0 5.3 GO:0043195 terminal bouton(GO:0043195)
0.0 2.1 GO:0032420 stereocilium(GO:0032420)
0.0 0.6 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.4 GO:0030057 desmosome(GO:0030057)
0.0 1.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.2 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 1.3 GO:0000123 histone acetyltransferase complex(GO:0000123)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 5.7 GO:0045322 unmethylated CpG binding(GO:0045322)
0.6 2.5 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.4 1.7 GO:0015057 thrombin receptor activity(GO:0015057)
0.3 1.3 GO:0051373 FATZ binding(GO:0051373)
0.2 4.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.2 0.6 GO:0019002 GMP binding(GO:0019002)
0.2 1.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.8 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.8 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 1.7 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 3.8 GO:0017166 vinculin binding(GO:0017166)
0.1 0.9 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.6 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 4.5 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 1.3 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.9 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 2.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.1 5.8 GO:0019003 GDP binding(GO:0019003)
0.1 1.6 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 3.5 GO:0004386 helicase activity(GO:0004386)
0.1 0.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 2.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 10.1 GO:0030674 protein binding, bridging(GO:0030674)
0.0 2.2 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.7 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.5 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 1.4 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.1 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 1.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.7 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.9 GO:0001614 purinergic nucleotide receptor activity(GO:0001614) nucleotide receptor activity(GO:0016502)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.7 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.7 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 9.8 GO:0016887 ATPase activity(GO:0016887)
0.0 4.8 GO:0008017 microtubule binding(GO:0008017)
0.0 0.9 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.5 GO:0005112 Notch binding(GO:0005112)
0.0 0.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 1.8 GO:0005249 voltage-gated potassium channel activity(GO:0005249)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.7 PID RAS PATHWAY Regulation of Ras family activation
0.1 5.0 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.1 1.4 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.5 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.7 ST GA12 PATHWAY G alpha 12 Pathway
0.0 4.5 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 1.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 2.0 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.6 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.6 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.3 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.3 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID EPO PATHWAY EPO signaling pathway
0.0 0.7 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.9 PID AR TF PATHWAY Regulation of Androgen receptor activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 5.1 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.4 4.3 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.3 5.8 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.2 4.9 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.2 1.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 3.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 2.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.1 1.4 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.1 2.1 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 1.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 3.2 REACTOME TOLL RECEPTOR CASCADES Genes involved in Toll Receptor Cascades
0.0 2.5 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.5 REACTOME ACTIVATION OF NF KAPPAB IN B CELLS Genes involved in Activation of NF-kappaB in B Cells
0.0 0.8 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 1.7 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors