Motif ID: AAAGUGC

Z-value: 1.476


Mature miRNA associated with seed AAAGUGC:

NamemiRBase Accession
mmu-miR-106a MIMAT0000385
mmu-miR-106b MIMAT0000386
mmu-miR-17 MIMAT0000649
mmu-miR-20a MIMAT0000529
mmu-miR-20b MIMAT0003187
mmu-miR-93 MIMAT0000540



Activity profile for motif AAAGUGC.

activity profile for motif AAAGUGC


Sorted Z-values histogram for motif AAAGUGC

Sorted Z-values for motif AAAGUGC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAAGUGC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_57651621 17.231 NM_019410
 Pfn2
profilin 2
chr5_+_104888468 15.099 NM_008861
 Pkd2
polycystic kidney disease 2
chrX_+_136145155 14.313 NM_023270
 Rnf128
ring finger protein 128
chr15_+_6249788 13.460 NM_001008702
 Dab2
disabled homolog 2 (Drosophila)
chr15_-_99705812 12.675 NM_001113545
 Lima1
LIM domain and actin binding 1
chr3_+_121426422 12.501 NM_010171
 F3
coagulation factor III
chr10_-_8605668 12.434 NM_175155
 Sash1
SAM and SH3 domain containing 1
chr6_+_34659440 12.316 NM_145575
 Cald1
caldesmon 1
chr15_-_99650502 12.095 NM_023063
 Lima1
LIM domain and actin binding 1
chr11_-_118216689 11.885 NM_011594
 Timp2
tissue inhibitor of metalloproteinase 2
chr1_-_74170987 11.701 NM_027884
 Tns1
tensin 1
chr8_-_26127376 11.428 NM_007404
 Adam9
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr7_-_125635435 10.947 NM_001033380
 Itpripl2
inositol 1,4,5-triphosphate receptor interacting protein-like 2
chr3_-_57379831 10.883 NM_001168281
 Wwtr1
WW domain containing transcription regulator 1
chr5_+_17080553 10.744 NM_013657
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr7_-_150927867 10.529 NM_024289
 Osbpl5
oxysterol binding protein-like 5
chr5_+_75552144 10.447 NM_001083316
 Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr9_-_123760686 10.372 NM_148925
 Fyco1
FYVE and coiled-coil domain containing 1
chr15_+_6336747 10.316 NM_001037905
NM_001102400
NM_023118
 Dab2


disabled homolog 2 (Drosophila)


chr17_+_29227908 10.101 NM_001111099
 Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 103 entries
Enrichment   P-value GO Accession GO Term
5.63 4.41e-02 GO:0016197 endosome transport
4.23 9.54e-05 GO:0046578 regulation of Ras protein signal transduction
4.11 3.49e-05 GO:0051056 regulation of small GTPase mediated signal transduction
3.65 2.24e-05 GO:0035295 tube development
3.61 4.49e-03 GO:0035239 tube morphogenesis
3.11 2.01e-02 GO:0002009 morphogenesis of an epithelium
3.04 4.67e-02 GO:0031329 regulation of cellular catabolic process
3.03 1.48e-03 GO:0051093 negative regulation of developmental process
2.96 3.30e-04 GO:0051726 regulation of cell cycle
2.96 2.56e-02 GO:0045596 negative regulation of cell differentiation
2.87 3.97e-03 GO:0060429 epithelium development
2.85 1.12e-05 GO:0042325 regulation of phosphorylation
2.85 1.74e-02 GO:0007167 enzyme linked receptor protein signaling pathway
2.82 8.63e-04 GO:0009967 positive regulation of signal transduction
2.79 1.18e-04 GO:0001932 regulation of protein phosphorylation
2.75 3.07e-05 GO:0019220 regulation of phosphate metabolic process
2.75 3.07e-05 GO:0051174 regulation of phosphorus metabolic process
2.68 2.98e-02 GO:0043549 regulation of kinase activity
2.67 1.80e-03 GO:0010647 positive regulation of cell communication
2.65 2.03e-03 GO:0023056 positive regulation of signaling

Gene overrepresentation in compartment category:

Showing 1 to 20 of 21 entries
Enrichment   P-value GO Accession GO Term
5.30 4.05e-03 GO:0005802 trans-Golgi network
5.01 1.67e-02 GO:0005604 basement membrane
4.21 2.95e-02 GO:0010008 endosome membrane
4.21 2.95e-02 GO:0044440 endosomal part
3.12 1.72e-03 GO:0044431 Golgi apparatus part
2.94 8.77e-05 GO:0005768 endosome
2.87 8.96e-03 GO:0048471 perinuclear region of cytoplasm
2.02 3.67e-03 GO:0005794 Golgi apparatus
1.44 4.30e-11 GO:0005737 cytoplasm
1.44 5.38e-03 GO:0005886 plasma membrane
1.43 2.48e-05 GO:0044444 cytoplasmic part
1.41 4.16e-04 GO:0005634 nucleus
1.41 1.30e-02 GO:0071944 cell periphery
1.38 2.14e-15 GO:0005622 intracellular
1.36 4.65e-13 GO:0044424 intracellular part
1.33 1.51e-07 GO:0043226 organelle
1.33 1.96e-07 GO:0043229 intracellular organelle
1.31 1.93e-05 GO:0043231 intracellular membrane-bounded organelle
1.31 2.33e-05 GO:0043227 membrane-bounded organelle
1.19 1.04e-09 GO:0005623 cell

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
Enrichment   P-value GO Accession GO Term
5.95 4.74e-02 GO:0046332 SMAD binding
4.66 2.46e-04 GO:0005085 guanyl-nucleotide exchange factor activity
3.58 2.84e-04 GO:0005083 small GTPase regulator activity
3.23 4.03e-03 GO:0019901 protein kinase binding
3.01 1.96e-04 GO:0030695 GTPase regulator activity
2.92 3.47e-04 GO:0060589 nucleoside-triphosphatase regulator activity
2.85 1.31e-02 GO:0019900 kinase binding
2.74 2.32e-02 GO:0016564 transcription repressor activity
2.41 2.05e-05 GO:0019899 enzyme binding
2.39 3.79e-05 GO:0030234 enzyme regulator activity
2.20 8.69e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.09 7.57e-03 GO:0016301 kinase activity
1.95 2.06e-02 GO:0030528 transcription regulator activity
1.83 4.26e-03 GO:0008270 zinc ion binding
1.62 4.41e-12 GO:0005515 protein binding
1.42 3.01e-02 GO:0046872 metal ion binding
1.41 4.72e-02 GO:0043169 cation binding
1.35 1.38e-12 GO:0005488 binding