Motif ID: AACGGAA

Z-value: 0.335


Mature miRNA associated with seed AACGGAA:

NamemiRBase Accession
mmu-miR-191 MIMAT0000221



Activity profile for motif AACGGAA.

activity profile for motif AACGGAA


Sorted Z-values histogram for motif AACGGAA

Sorted Z-values for motif AACGGAA



Network of associatons between targets according to the STRING database.



First level regulatory network of AACGGAA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_42340613 5.945 NM_008083
Gap43
growth associated protein 43
chr2_+_109533719 5.527 NM_001048142
Bdnf
brain derived neurotrophic factor
chr2_+_109532592 4.855 NM_001048141
Bdnf
brain derived neurotrophic factor
chr2_+_109514856 4.317 NM_007540
Bdnf
brain derived neurotrophic factor
chr2_+_109516053 3.410 NM_001048139
Bdnf
brain derived neurotrophic factor
chr12_+_45429857 3.169 NM_001146031
NM_176930
Nrcam

neuron-glia-CAM-related cell adhesion molecule

chr5_+_31117077 3.143 NM_133350
Mapre3
microtubule-associated protein, RP/EB family, member 3
chr2_+_71367501 3.102 NM_010053
Dlx1
distal-less homeobox 1
chr2_+_164793487 2.619 NM_020333
Slc12a5
solute carrier family 12, member 5
chrX_-_13423666 2.463 NM_009806
Cask
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr14_-_26588341 1.368 NM_001101433
Zcchc24
zinc finger, CCHC domain containing 24
chr6_-_113841356 1.324 NM_001036684
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr4_+_97444312 1.253 NM_001122953
NM_010905
Nfia

nuclear factor I/A

chr4_+_139131050 1.118 NM_183148
Iffo2
intermediate filament family orphan 2
chr6_-_113991945 1.078 NM_009723
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr12_-_5382487 1.012 NM_001164493
Klhl29
kelch-like 29 (Drosophila)
chr2_+_31428244 0.542 NM_001033389
Fubp3
far upstream element (FUSE) binding protein 3
chr18_-_60872888 0.423 NM_008306
Ndst1
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 1
chr8_-_91568060 0.390 NM_021390
Sall1
sal-like 1 (Drosophila)
chr15_-_102347434 0.266 NM_001163643
NM_009582
Map3k12

mitogen-activated protein kinase kinase kinase 12

chr4_+_97248556 0.239 NM_001122952
Nfia
D130039L10Rik
nuclear factor I/A
RIKEN cDNA D130039L10 gene
chr5_+_114830615 0.225 NM_054093
Ube3b
ubiquitin protein ligase E3B
chr17_-_32524703 0.178 NM_212438
Wiz
widely-interspaced zinc finger motifs
chr2_+_167514414 0.150 NM_009883
Cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr11_+_69715343 0.082 NM_001013414
Neurl4
neuralized homolog 4 (Drosophila)
chr17_+_73267643 0.052 NM_029999
Lbh
limb-bud and heart
chr1_-_64784316 0.017 NM_001042659
NM_022721
Fzd5

frizzled homolog 5 (Drosophila)


Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
9.38 1.85e-04 GO:0048699 generation of neurons
11.73 2.41e-04 GO:0030182 neuron differentiation
8.79 3.03e-04 GO:0022008 neurogenesis
6.95 3.91e-04 GO:0007399 nervous system development
7.44 1.06e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
17.90 1.41e-03 GO:0048667 cell morphogenesis involved in neuron differentiation
12.04 1.42e-03 GO:0007417 central nervous system development
15.28 3.05e-03 GO:0048568 embryonic organ development
14.12 4.47e-03 GO:0000904 cell morphogenesis involved in differentiation
12.92 6.83e-03 GO:0007420 brain development
19.93 8.95e-03 GO:0045165 cell fate commitment
5.35 1.20e-02 GO:0009653 anatomical structure morphogenesis
10.56 1.79e-02 GO:0048666 neuron development
10.19 2.13e-02 GO:0000902 cell morphogenesis
15.71 2.26e-02 GO:0007409 axonogenesis
7.11 2.79e-02 GO:0045893 positive regulation of transcription, DNA-dependent
7.00 3.03e-02 GO:0051254 positive regulation of RNA metabolic process
9.36 3.16e-02 GO:0032989 cellular component morphogenesis
9.12 3.57e-02 GO:0030030 cell projection organization
13.70 3.84e-02 GO:0048812 neuron projection morphogenesis
8.93 3.94e-02 GO:0043009 chordate embryonic development
6.64 4.05e-02 GO:0009790 embryo development
8.81 4.22e-02 GO:0009792 embryo development ending in birth or egg hatching
6.52 4.46e-02 GO:0010628 positive regulation of gene expression

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
9.23 1.26e-03 GO:0043005 neuron projection
5.70 5.29e-03 GO:0042995 cell projection

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
12.92 1.54e-03 GO:0016563 transcription activator activity
20.78 1.87e-02 GO:0005516 calmodulin binding