Motif ID: AAGGUGC

Z-value: 0.776


Mature miRNA associated with seed AAGGUGC:

NamemiRBase Accession
mmu-miR-18a MIMAT0000528
mmu-miR-18b MIMAT0004858



Activity profile for motif AAGGUGC.

activity profile for motif AAGGUGC


Sorted Z-values histogram for motif AAGGUGC

Sorted Z-values for motif AAGGUGC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGGUGC

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_92697567 14.820 NM_001111023
NM_009821
 Runx1

runt related transcription factor 1

chr16_-_92826307 11.456 NM_001111021
NM_001111022
 Runx1

runt related transcription factor 1

chr3_+_60305108 10.912 NM_020007
 Mbnl1
muscleblind-like 1 (Drosophila)
chr15_+_78813475 10.056 NM_001024716
 Triobp
TRIO and F-actin binding protein
chr13_-_41454358 10.053 NM_017464
 Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr10_-_18731766 9.991 NM_001166402
 Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr16_+_24721940 9.801 NM_001145954
 Lpp
LIM domain containing preferred translocation partner in lipoma
chr5_+_75971011 9.279 NM_001122733
NM_021099
 Kit

kit oncogene

chr16_+_24393435 9.014 NM_178665
 Lpp
LIM domain containing preferred translocation partner in lipoma
chr16_+_24448176 8.644 NM_001145952
 Lpp
LIM domain containing preferred translocation partner in lipoma
chr10_-_18735154 8.078 NM_009397
 Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr10_+_40069113 7.989 NM_001168304
NM_198164
 Cdk19

cyclin-dependent kinase 19

chr5_+_97426665 7.796 NM_080708
 Bmp2k
BMP2 inducible kinase
chr3_-_30868320 7.532 NM_001165954
NM_001165955
NM_001165956
NM_153421
 Phc3



polyhomeotic-like 3 (Drosophila)



chr13_-_41582649 7.053 NM_001111324
 Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr15_+_78778153 6.952 NM_001039155
NM_001039156
NM_138579
 Triobp


TRIO and F-actin binding protein


chr2_+_112106470 6.856 NM_133649
 Slc12a6
solute carrier family 12, member 6
chr8_-_36558514 6.053 NM_026067
 Eri1
exoribonuclease 1
chr5_+_32438843 6.023 NM_008037
 Fosl2
fos-like antigen 2
chr13_-_46060325 5.973 NM_009124
 Atxn1
ataxin 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 69 entries
Enrichment   P-value GO Accession GO Term
12.54 4.98e-02 GO:0048146 positive regulation of fibroblast proliferation
10.71 2.14e-02 GO:0048145 regulation of fibroblast proliferation
9.69 8.34e-03 GO:0010741 negative regulation of intracellular protein kinase cascade
3.38 1.42e-02 GO:0060548 negative regulation of cell death
3.32 3.24e-02 GO:0043069 negative regulation of programmed cell death
3.26 7.56e-04 GO:0006468 protein phosphorylation
3.19 1.16e-04 GO:0010628 positive regulation of gene expression
3.09 1.10e-03 GO:0045893 positive regulation of transcription, DNA-dependent
3.06 3.03e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
3.04 1.43e-03 GO:0051254 positive regulation of RNA metabolic process
3.00 1.11e-03 GO:0016310 phosphorylation
2.99 4.24e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
2.93 2.21e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.91 7.01e-04 GO:0042127 regulation of cell proliferation
2.87 3.31e-04 GO:0043067 regulation of programmed cell death
2.84 1.75e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
2.81 8.60e-04 GO:0042981 regulation of apoptosis
2.80 5.70e-04 GO:0010941 regulation of cell death
2.80 3.62e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.79 1.81e-12 GO:0051252 regulation of RNA metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 8 of 8 entries
Enrichment   P-value GO Accession GO Term
2.00 3.01e-12 GO:0005634 nucleus
1.92 1.83e-02 GO:0044428 nuclear part
1.47 5.78e-06 GO:0043231 intracellular membrane-bounded organelle
1.46 6.62e-06 GO:0043227 membrane-bounded organelle
1.36 3.95e-04 GO:0043229 intracellular organelle
1.35 4.71e-04 GO:0043226 organelle
1.31 2.13e-04 GO:0044424 intracellular part
1.30 2.45e-04 GO:0005622 intracellular

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
Enrichment   P-value GO Accession GO Term
4.01 1.08e-02 GO:0046982 protein heterodimerization activity
3.69 1.72e-03 GO:0004674 protein serine/threonine kinase activity
3.21 1.73e-03 GO:0004672 protein kinase activity
2.92 9.33e-04 GO:0001071 nucleic acid binding transcription factor activity
2.92 9.33e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
2.83 6.36e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.82 4.18e-03 GO:0046983 protein dimerization activity
2.52 2.13e-02 GO:0016301 kinase activity
2.35 8.20e-04 GO:0008270 zinc ion binding
2.25 1.45e-04 GO:0003677 DNA binding
2.18 9.79e-07 GO:0003676 nucleic acid binding
2.08 5.68e-03 GO:0046914 transition metal ion binding
1.98 1.14e-06 GO:0046872 metal ion binding
1.97 1.77e-02 GO:0016740 transferase activity
1.96 1.87e-06 GO:0043169 cation binding
1.95 2.17e-06 GO:0043167 ion binding
1.60 4.00e-05 GO:0005515 protein binding
1.50 1.08e-12 GO:0005488 binding