Motif ID: AAGGUGC

Z-value: 0.776


Mature miRNA associated with seed AAGGUGC:

NamemiRBase Accession
mmu-miR-18a MIMAT0000528
mmu-miR-18b MIMAT0004858



Activity profile for motif AAGGUGC.

activity profile for motif AAGGUGC


Sorted Z-values histogram for motif AAGGUGC

Sorted Z-values for motif AAGGUGC



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGGUGC

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_-_92697567 14.820 NM_001111023
NM_009821
Runx1

runt related transcription factor 1

chr16_-_92826307 11.456 NM_001111021
NM_001111022
Runx1

runt related transcription factor 1

chr3_+_60305108 10.912 NM_020007
Mbnl1
muscleblind-like 1 (Drosophila)
chr15_+_78813475 10.056 NM_001024716
Triobp
TRIO and F-actin binding protein
chr13_-_41454358 10.053 NM_017464
Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr10_-_18731766 9.991 NM_001166402
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr16_+_24721940 9.801 NM_001145954
Lpp
LIM domain containing preferred translocation partner in lipoma
chr5_+_75971011 9.279 NM_001122733
NM_021099
Kit

kit oncogene

chr16_+_24393435 9.014 NM_178665
Lpp
LIM domain containing preferred translocation partner in lipoma
chr16_+_24448176 8.644 NM_001145952
Lpp
LIM domain containing preferred translocation partner in lipoma
chr10_-_18735154 8.078 NM_009397
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr10_+_40069113 7.989 NM_001168304
NM_198164
Cdk19

cyclin-dependent kinase 19

chr5_+_97426665 7.796 NM_080708
Bmp2k
BMP2 inducible kinase
chr3_-_30868320 7.532 NM_001165954
NM_001165955
NM_001165956
NM_153421
Phc3



polyhomeotic-like 3 (Drosophila)



chr13_-_41582649 7.053 NM_001111324
Nedd9
neural precursor cell expressed, developmentally down-regulated gene 9
chr15_+_78778153 6.952 NM_001039155
NM_001039156
NM_138579
Triobp


TRIO and F-actin binding protein


chr2_+_112106470 6.856 NM_133649
Slc12a6
solute carrier family 12, member 6
chr8_-_36558514 6.053 NM_026067
Eri1
exoribonuclease 1
chr5_+_32438843 6.023 NM_008037
Fosl2
fos-like antigen 2
chr13_-_46060325 5.973 NM_009124
Atxn1
ataxin 1
chr4_+_118102305 5.570 NM_001039176
Elovl1
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr2_+_112124767 5.280 NM_133648
Slc12a6
solute carrier family 12, member 6
chr6_+_133985717 4.735 NM_007961
Etv6
ets variant gene 6 (TEL oncogene)
chr11_+_69579376 4.724 NM_029348
Zbtb4
zinc finger and BTB domain containing 4
chr11_-_94538693 4.722 NM_145828
Xylt2
xylosyltransferase II
chr15_+_80541675 4.572 NM_144812
Tnrc6b
trinucleotide repeat containing 6b
chr13_-_112599181 4.489 NM_011945
Map3k1
mitogen-activated protein kinase kinase kinase 1
chr6_-_134742645 4.384 NM_001048054
NM_130447
Dusp16

dual specificity phosphatase 16

chr4_+_118100682 4.377 NM_001039175
NM_019422
Elovl1

elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1

chr7_+_134913327 4.119 NM_198424
Orai3
ORAI calcium release-activated calcium modulator 3
chr9_+_30838224 4.116 NM_001115130
NM_172765
Zbtb44

zinc finger and BTB domain containing 44

chr6_+_140572056 4.105 NM_001005605
Aebp2
AE binding protein 2
chr18_-_39646734 4.048 NM_008173
Nr3c1
nuclear receptor subfamily 3, group C, member 1
chr4_+_64785207 4.036 NM_021362
Pappa
pregnancy-associated plasma protein A
chr8_-_112261607 4.005 NM_001080930
Atxn1l
ataxin 1-like
chr16_-_50432421 3.903 NM_027444
Bbx
bobby sox homolog (Drosophila)
chr18_+_76401531 3.793 NM_010754
Smad2
MAD homolog 2 (Drosophila)
chr2_+_163899842 3.766 NM_021420
Stk4
serine/threonine kinase 4
chr10_+_43198945 3.651 NM_199028
Bend3
BEN domain containing 3
chr9_+_118835589 3.530 NM_133710
Ctdspl
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr2_-_34769479 3.361 NM_028716
Phf19
PHD finger protein 19
chr1_+_136456754 3.361 NM_152895
Kdm5b
lysine (K)-specific demethylase 5B
chr10_-_5734448 3.248 NM_007956
Esr1
estrogen receptor 1 (alpha)
chr1_-_63160764 3.246 NM_001081436
NM_001114609
Ino80d

INO80 complex subunit D

chr5_-_73647856 3.239 NM_028194
Fryl
furry homolog-like (Drosophila)
chr12_+_75008853 3.202 NM_010431
Hif1a
hypoxia inducible factor 1, alpha subunit
chr11_+_4167080 3.129 NM_001039537
Lif
leukemia inhibitory factor
chr15_+_80629020 2.977 NM_177124
Tnrc6b
trinucleotide repeat containing 6b
chr19_+_32832002 2.921 NM_008960
Pten
phosphatase and tensin homolog
chr3_+_97817440 2.903 NM_010928
Notch2
Notch gene homolog 2 (Drosophila)
chr13_-_48966240 2.897 NM_011078
Phf2
PHD finger protein 2
chr11_+_4157570 2.818 NM_008501
Lif
leukemia inhibitory factor
chr3_-_100914081 2.520 NM_011197
Ptgfrn
prostaglandin F2 receptor negative regulator
chr10_+_87321789 2.473 NM_001111275
NM_010512
Igf1

insulin-like growth factor 1

chr2_-_24775083 2.369 NM_001012518
NM_001109686
NM_001109687
NM_172545
Ehmt1



euchromatic histone methyltransferase 1



chr16_+_94085504 2.313 NM_011377
Sim2
single-minded homolog 2 (Drosophila)
chr17_+_86020173 2.290 NM_011381
Six3
sine oculis-related homeobox 3 homolog (Drosophila)
chr17_+_78599556 2.185 NM_015800
Crim1
cysteine rich transmembrane BMP regulator 1 (chordin like)
chr7_+_108257288 2.141 NM_001146010
NM_199012
Fchsd2

FCH and double SH3 domains 2

chr16_+_44139908 2.099 NM_028108
Naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr6_+_140571183 2.096 NM_178803
Aebp2
AE binding protein 2
chr2_+_36085945 2.065 NM_008969
Ptgs1
prostaglandin-endoperoxide synthase 1
chr3_-_9610062 1.973 NM_133218
Zfp704
zinc finger protein 704
chr8_+_47825098 1.906 NM_008391
Irf2
interferon regulatory factor 2
chr4_+_105988790 1.905 NM_183225
Usp24
ubiquitin specific peptidase 24
chr13_-_94269616 1.885 NM_021310
Jmy
junction-mediating and regulatory protein
chr1_+_40496493 1.881 NM_010743
Il1rl1
interleukin 1 receptor-like 1
chr12_+_3426883 1.855 NM_172421
Asxl2
additional sex combs like 2 (Drosophila)
chr11_+_77499638 1.750 NM_001024205
Nufip2
nuclear fragile X mental retardation protein interacting protein 2
chr3_+_96500993 1.712 NM_001165949
NM_018812
Pias3

protein inhibitor of activated STAT 3

chr9_-_53344748 1.668 NM_007499
Atm
ataxia telangiectasia mutated homolog (human)
chr13_-_74429744 1.657 NM_009644
Ahrr
aryl-hydrocarbon receptor repressor
chr9_-_88376937 1.649 NM_019666
NM_019796
Syncrip

synaptotagmin binding, cytoplasmic RNA interacting protein

chr3_-_38383688 1.646 NM_001167883
Ankrd50
ankyrin repeat domain 50
chr10_+_79957650 1.579 NM_139226
Onecut3
one cut domain, family member 3
chr3_-_146475652 1.569 NM_011100
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr11_+_58028478 1.523 NM_019440
Irgm2
immunity-related GTPase family M member 2
chr8_-_70498472 1.462 NM_177698
Psd3
pleckstrin and Sec7 domain containing 3
chr14_-_20642973 1.392 NM_026528
2700060E02Rik
RIKEN cDNA 2700060E02 gene
chr12_-_85559793 1.383 NM_001163501
C130039O16Rik
RIKEN cDNA C130039O16 gene
chr13_+_34094742 1.350 NM_009068
Ripk1
receptor (TNFRSF)-interacting serine-threonine kinase 1
chr2_+_72123693 1.276 NM_023057
NM_001164791
NM_178084
B230120H23Rik


RIKEN cDNA B230120H23 gene


chr6_+_108778633 1.273 NM_138677
Edem1
ER degradation enhancer, mannosidase alpha-like 1
chr1_-_132994093 1.234 NM_008551
Mapkapk2
MAP kinase-activated protein kinase 2
chr11_+_59120429 1.216 NM_139298
Wnt9a
wingless-type MMTV integration site 9A
chr5_-_116474254 1.206 NM_031869
Prkab1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr2_+_117937623 1.163 NM_011580
Thbs1
thrombospondin 1
chr9_-_35007875 1.154 NM_001177845
Tirap
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
chr11_+_29273673 1.147 NM_176841
Ccdc88a
coiled coil domain containing 88A
chr16_-_85901362 1.134 NM_011782
Adamts5
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
chr16_-_22163264 1.117 NM_183029
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr14_+_70945429 1.109 NM_180588
Reep4
receptor accessory protein 4
chr18_+_66618186 1.025 NM_021451
Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
chr2_+_154959216 1.010 NM_008395
Itch
itchy, E3 ubiquitin protein ligase
chr15_+_73578455 1.005 NM_008975
Ptp4a3
protein tyrosine phosphatase 4a3
chr13_-_64254466 0.984 NM_175494
Zfp367
zinc finger protein 367
chr2_-_153067043 0.983 NM_018807
Plagl2
pleiomorphic adenoma gene-like 2
chr9_-_35007458 0.974 NM_001177847
NM_001177846
NM_054096
Tirap


toll-interleukin 1 receptor (TIR) domain-containing adaptor protein


chr16_-_44028057 0.952 NM_001172107
Gramd1c
GRAM domain containing 1C
chr2_+_153067186 0.951 NM_080463
Pofut1
protein O-fucosyltransferase 1
chr15_+_10882086 0.942 NM_030888
C1qtnf3
C1q and tumor necrosis factor related protein 3
chr3_+_96500294 0.928 NM_146135
Pias3
protein inhibitor of activated STAT 3
chr1_+_52176281 0.924 NM_009283
Stat1
signal transducer and activator of transcription 1
chr6_+_86992796 0.909 NM_013528
Gfpt1
glutamine fructose-6-phosphate transaminase 1
chr10_-_127930880 0.905 NM_010860
Myl6
myosin, light polypeptide 6, alkali, smooth muscle and non-muscle
chr16_+_32332294 0.887 NM_177633
Ubxn7
UBX domain protein 7
chr12_-_92828018 0.878 NM_031391
Gtf2a1
general transcription factor II A, 1
chr3_+_88489708 0.871 NM_028814
2810403A07Rik
RIKEN cDNA 2810403A07 gene
chr4_+_147314951 0.852 NM_029841
2510039O18Rik
RIKEN cDNA 2510039O18 gene
chr16_+_34785006 0.845 NM_139300
Mylk
myosin, light polypeptide kinase
chr7_+_17401237 0.840 NM_001039878
NM_133789
Strn4

striatin, calmodulin binding protein 4

chrX_+_102275071 0.833 NM_026312
2610029G23Rik
RIKEN cDNA 2610029G23 gene
chr5_+_139856534 0.819 NM_030258
Gpr146
G protein-coupled receptor 146
chr16_-_44016471 0.811 NM_153528
Gramd1c
GRAM domain containing 1C
chr5_+_91503642 0.805 NM_007950
Ereg
epiregulin
chr17_-_30024821 0.776 NM_001081160
Mdga1
MAM domain containing glycosylphosphatidylinositol anchor 1
chr19_+_53218486 0.769 NM_013758
Add3
adducin 3 (gamma)
chr8_+_109817355 0.767 NM_018823
NM_133957
Nfat5

nuclear factor of activated T-cells 5

chr8_+_72315061 0.761 NM_133224
Atp13a1
ATPase type 13A1
chr1_-_45560001 0.751 NM_007737
Col5a2
collagen, type V, alpha 2
chr6_+_55286292 0.745 NM_007472
Aqp1
aquaporin 1
chr2_-_52601140 0.727 NM_019667
Stam2
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr3_+_14641726 0.723 NM_024495
Car13
carbonic anhydrase 13
chr19_+_57435498 0.711 NM_145505
Fam160b1
family with sequence similarity 160, member B1
chrX_-_16394443 0.699 NM_172778
Maob
monoamine oxidase B
chr10_-_128082881 0.676 NM_011772
Ikzf4
IKAROS family zinc finger 4
chr12_-_85534964 0.655 NM_001163502
C130039O16Rik
RIKEN cDNA C130039O16 gene
chr10_+_87323855 0.625 NM_001111274
NM_001111276
NM_184052
Igf1


insulin-like growth factor 1


chr19_+_21346734 0.624 NM_009551
Zfand5
zinc finger, AN1-type domain 5
chr10_+_68675404 0.609 NM_001081347
Rhobtb1
Rho-related BTB domain containing 1
chr11_+_86298106 0.597 NM_029788
Rnft1
ring finger protein, transmembrane 1
chr5_+_139865857 0.596 NM_001038703
Gpr146
G protein-coupled receptor 146
chr5_+_130695613 0.589 NM_001081394
0610007L01Rik
RIKEN cDNA 0610007L01 gene
chr18_+_53624169 0.577 NM_001033281
Prdm6
PR domain containing 6
chr17_-_32925218 0.570 NM_172458
Zfp871
zinc finger protein 871
chr14_-_32064403 0.554 NM_027949
Phf7
PHD finger protein 7
chr13_-_104124527 0.547 NM_175171
Mast4
microtubule associated serine/threonine kinase family member 4
chr18_+_9957913 0.533 NM_153552
Thoc1
THO complex 1
chr11_+_49016828 0.532 NM_001024846
NM_009562
Zfp62

zinc finger protein 62

chr17_+_64287320 0.523 NM_008000
Fert2
fer (fms/fps related) protein kinase, testis specific 2
chr18_-_78320126 0.522 NM_001171010
NM_028122
Slc14a1

solute carrier family 14 (urea transporter), member 1

chr18_-_78338857 0.516 NM_001171011
Slc14a1
solute carrier family 14 (urea transporter), member 1
chr5_+_136514365 0.513 NM_175309
Upk3b
uroplakin 3B
chr4_-_15940946 0.502 NM_145950
Osgin2
oxidative stress induced growth inhibitor family member 2
chr18_+_32227377 0.501 NM_173441
Iws1
IWS1 homolog (S. cerevisiae)
chr6_+_21899614 0.494 NM_023626
Ing3
inhibitor of growth family, member 3
chr1_+_70772288 0.492 NM_177164
Vwc2l
von Willebrand factor C domain-containing protein 2-like
chr8_-_48760457 0.482 NM_023503
Ing2
inhibitor of growth family, member 2
chr1_-_137481914 0.467 NM_173437
Nav1
neuron navigator 1
chr6_+_134961629 0.460 NM_026360
Ddx47
DEAD (Asp-Glu-Ala-Asp) box polypeptide 47
chr17_+_53706283 0.458 NM_020005
Kat2b
K(lysine) acetyltransferase 2B
chr17_+_26852581 0.456 NM_029870
A930001N09Rik
RIKEN cDNA A930001N09 gene
chr1_+_19198994 0.446 NM_009334
Tcfap2b
transcription factor AP-2 beta
chr11_-_77421308 0.443 NM_144825
Taok1
TAO kinase 1
chrX_-_141921588 0.442 NM_153319
Amot
angiomotin
chr5_-_137548123 0.437 NM_008871
Serpine1
serine (or cysteine) peptidase inhibitor, clade E, member 1
chr4_-_155366696 0.419 NM_080445
B3galt6
UDP-Gal:betaGal beta 1,3-galactosyltransferase, polypeptide 6
chr6_+_86354212 0.417 NM_001164078
NM_001164079
NM_011585
Tia1


cytotoxic granule-associated RNA binding protein 1


chr5_+_73039034 0.414 NM_001081205
Nipal1
NIPA-like domain containing 1
chr17_-_56323312 0.414 NM_080837
D17Wsu104e
DNA segment, Chr 17, Wayne State University 104, expressed
chr1_-_12980994 0.413 NM_172841
Slco5a1
solute carrier organic anion transporter family, member 5A1
chr1_-_162964371 0.411 NM_173424
Zbtb37
zinc finger and BTB domain containing 37
chr2_-_56967331 0.404 NM_013613
Nr4a2
nuclear receptor subfamily 4, group A, member 2
chr6_-_119988624 0.401 NM_001185020
NM_001185021
NM_198703
Wnk1


WNK lysine deficient protein kinase 1


chr15_+_80453912 0.401 NM_010815
Grap2
GRB2-related adaptor protein 2
chr17_+_53723450 0.389 NM_001190846
Kat2b
K(lysine) acetyltransferase 2B
chr17_+_64245366 0.386 NM_001037997
Fert2
fer (fms/fps related) protein kinase, testis specific 2
chr15_-_56526052 0.379 NM_008216
Has2
hyaluronan synthase 2
chr11_+_51398258 0.367 NM_028398
Agxt2l2
alanine-glyoxylate aminotransferase 2-like 2
chr17_-_66300454 0.353 NM_023053
Twsg1
twisted gastrulation homolog 1 (Drosophila)
chr19_+_53214934 0.341 NM_001164099
NM_001164101
Add3

adducin 3 (gamma)

chr8_-_120195414 0.339 NM_028725
Sdr42e1
short chain dehydrogenase/reductase family 42E, member 1
chr19_-_42687234 0.333 NM_001164311
NM_053083
Loxl4

lysyl oxidase-like 4

chr15_+_73555336 0.327 NM_001166388
Ptp4a3
protein tyrosine phosphatase 4a3
chr15_+_99869071 0.321 NM_001159361
Dip2b
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr1_-_43155380 0.320 NM_001013025
Tgfbrap1
transforming growth factor, beta receptor associated protein 1
chr9_-_14185685 0.304 NM_028013
Endod1
endonuclease domain containing 1
chr18_+_62483857 0.304 NM_008313
Htr4
5 hydroxytryptamine (serotonin) receptor 4
chr3_+_54559503 0.299 NM_019483
Smad9
MAD homolog 9 (Drosophila)
chr4_+_114079291 0.291 NM_001085549
Gm12824
predicted gene 12824
chr9_-_65732843 0.289 NM_001170907
Trip4
thyroid hormone receptor interactor 4
chr1_+_82583495 0.286 NM_007734
Col4a3
collagen, type IV, alpha 3
chr10_+_57206184 0.284 NM_008297
Hsf2
heat shock factor 2
chr3_-_146433200 0.280 NM_001164198
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr14_+_65977510 0.280 NM_199029
Zfp395
zinc finger protein 395
chr6_+_34813131 0.267 NM_197986
Tmem140
transmembrane protein 140
chr5_-_139060952 0.263 NM_001044747
NM_001163797
NM_013844
Zfp68


zinc finger protein 68


chr1_-_33726582 0.258 NM_008922
Prim2
DNA primase, p58 subunit
chr6_-_39675456 0.254 NM_139294
Braf
Braf transforming gene
chr9_+_115818572 0.253 NM_028638
Gadl1
glutamate decarboxylase-like 1
chr15_+_73553574 0.249 NM_001166389
NM_001166390
Ptp4a3

protein tyrosine phosphatase 4a3

chr9_+_118387306 0.246 NM_001164789
NM_010136
Eomes

eomesodermin homolog (Xenopus laevis)

chr13_-_93914519 0.245 NM_023821
Cmya5
cardiomyopathy associated 5
chr4_-_139388882 0.245 NM_011039
Pax7
paired box gene 7
chr13_+_41701584 0.244 NM_001163572
Tmem170b
transmembrane protein 170B
chr2_+_91493364 0.241 NM_146124
Arhgap1
Rho GTPase activating protein 1
chr2_+_75497282 0.237 NM_053263
NM_146130
NM_198090
Hnrnpa3


Gm6793
heterogeneous nuclear ribonucleoprotein A3


heterogeneous nuclear ribonucleoprotein A3 pseudogene
chr7_-_91234908 0.233 NM_030728
9930013L23Rik
RIKEN cDNA 9930013L23 gene
chr5_+_137443701 0.231 NM_021719
Cldn15
claudin 15
chr1_+_19202046 0.227 NM_001025305
Tcfap2b
transcription factor AP-2 beta

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.42 9.99e-14 GO:0080090 regulation of primary metabolic process
2.73 1.09e-13 GO:0010468 regulation of gene expression
2.40 1.56e-13 GO:0031323 regulation of cellular metabolic process
2.42 4.89e-13 GO:0060255 regulation of macromolecule metabolic process
2.25 9.75e-13 GO:0019222 regulation of metabolic process
2.73 9.97e-13 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.79 1.81e-12 GO:0051252 regulation of RNA metabolic process
2.67 3.59e-12 GO:0010556 regulation of macromolecule biosynthetic process
2.58 6.39e-12 GO:0051171 regulation of nitrogen compound metabolic process
2.57 1.29e-11 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.56 1.80e-11 GO:0031326 regulation of cellular biosynthetic process
2.52 3.44e-11 GO:0009889 regulation of biosynthetic process
2.68 1.18e-10 GO:0006355 regulation of transcription, DNA-dependent
1.98 1.33e-09 GO:0044260 cellular macromolecule metabolic process
2.48 2.26e-08 GO:0016070 RNA metabolic process
2.76 4.58e-08 GO:0006351 transcription, DNA-dependent
2.76 4.88e-08 GO:0032774 RNA biosynthetic process
1.69 1.91e-07 GO:0044237 cellular metabolic process
1.80 2.41e-07 GO:0043170 macromolecule metabolic process
2.26 2.73e-07 GO:0090304 nucleic acid metabolic process
2.12 3.24e-07 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.26 4.56e-06 GO:0034645 cellular macromolecule biosynthetic process
2.24 6.14e-06 GO:0009059 macromolecule biosynthetic process
2.19 6.71e-06 GO:0010467 gene expression
1.61 8.86e-06 GO:0044238 primary metabolic process
1.95 9.29e-06 GO:0034641 cellular nitrogen compound metabolic process
1.92 1.15e-05 GO:0006807 nitrogen compound metabolic process
2.22 1.76e-05 GO:0048519 negative regulation of biological process
2.02 1.90e-05 GO:0044249 cellular biosynthetic process
1.99 2.37e-05 GO:0009058 biosynthetic process
2.67 2.77e-05 GO:0009893 positive regulation of metabolic process
2.74 3.41e-05 GO:0010604 positive regulation of macromolecule metabolic process
2.13 4.66e-05 GO:0048522 positive regulation of cellular process
1.51 5.51e-05 GO:0008152 metabolic process
2.45 7.11e-05 GO:0006464 protein modification process
2.02 1.06e-04 GO:0048518 positive regulation of biological process
3.19 1.16e-04 GO:0010628 positive regulation of gene expression
2.93 2.21e-04 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.34 2.67e-04 GO:0043412 macromolecule modification
2.87 3.31e-04 GO:0043067 regulation of programmed cell death
2.99 4.24e-04 GO:0010557 positive regulation of macromolecule biosynthetic process
2.54 5.14e-04 GO:0031325 positive regulation of cellular metabolic process
2.80 5.70e-04 GO:0010941 regulation of cell death
2.91 7.01e-04 GO:0042127 regulation of cell proliferation
3.26 7.56e-04 GO:0006468 protein phosphorylation
2.11 8.24e-04 GO:0048523 negative regulation of cellular process
2.81 8.60e-04 GO:0042981 regulation of apoptosis
3.09 1.10e-03 GO:0045893 positive regulation of transcription, DNA-dependent
3.00 1.11e-03 GO:0016310 phosphorylation
2.74 1.39e-03 GO:0006796 phosphate metabolic process
3.04 1.43e-03 GO:0051254 positive regulation of RNA metabolic process
2.74 1.45e-03 GO:0006793 phosphorus metabolic process
2.78 1.71e-03 GO:0031328 positive regulation of cellular biosynthetic process
2.84 1.75e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
2.72 2.47e-03 GO:0009891 positive regulation of biosynthetic process
2.80 3.62e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.41 3.92e-03 GO:0050794 regulation of cellular process
1.39 6.10e-03 GO:0050789 regulation of biological process
9.69 8.34e-03 GO:0010741 negative regulation of intracellular protein kinase cascade
1.96 1.03e-02 GO:0044267 cellular protein metabolic process
3.38 1.42e-02 GO:0060548 negative regulation of cell death
2.56 1.77e-02 GO:0032268 regulation of cellular protein metabolic process
2.48 2.02e-02 GO:0050793 regulation of developmental process
10.71 2.14e-02 GO:0048145 regulation of fibroblast proliferation
3.06 3.03e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
3.32 3.24e-02 GO:0043069 negative regulation of programmed cell death
2.73 3.40e-02 GO:0031399 regulation of protein modification process
2.03 3.72e-02 GO:0042221 response to chemical stimulus
12.54 4.98e-02 GO:0048146 positive regulation of fibroblast proliferation

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.00 3.01e-12 GO:0005634 nucleus
1.47 5.78e-06 GO:0043231 intracellular membrane-bounded organelle
1.46 6.62e-06 GO:0043227 membrane-bounded organelle
1.31 2.13e-04 GO:0044424 intracellular part
1.30 2.45e-04 GO:0005622 intracellular
1.36 3.95e-04 GO:0043229 intracellular organelle
1.35 4.71e-04 GO:0043226 organelle
1.92 1.83e-02 GO:0044428 nuclear part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.50 1.08e-12 GO:0005488 binding
2.18 9.79e-07 GO:0003676 nucleic acid binding
1.98 1.14e-06 GO:0046872 metal ion binding
1.96 1.87e-06 GO:0043169 cation binding
1.95 2.17e-06 GO:0043167 ion binding
1.60 4.00e-05 GO:0005515 protein binding
2.25 1.45e-04 GO:0003677 DNA binding
2.35 8.20e-04 GO:0008270 zinc ion binding
2.92 9.33e-04 GO:0001071 nucleic acid binding transcription factor activity
2.92 9.33e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
3.69 1.72e-03 GO:0004674 protein serine/threonine kinase activity
3.21 1.73e-03 GO:0004672 protein kinase activity
2.82 4.18e-03 GO:0046983 protein dimerization activity
2.08 5.68e-03 GO:0046914 transition metal ion binding
2.83 6.36e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
4.01 1.08e-02 GO:0046982 protein heterodimerization activity
1.97 1.77e-02 GO:0016740 transferase activity
2.52 2.13e-02 GO:0016301 kinase activity