Motif ID: AAGUGCU

Z-value: 1.294


Mature miRNA associated with seed AAGUGCU:

NamemiRBase Accession
mmu-miR-291a-3p MIMAT0000368
mmu-miR-294 MIMAT0000372
mmu-miR-295 MIMAT0000373
mmu-miR-302a MIMAT0000380
mmu-miR-302b MIMAT0003374
mmu-miR-302d MIMAT0003377



Activity profile for motif AAGUGCU.

activity profile for motif AAGUGCU


Sorted Z-values histogram for motif AAGUGCU

Sorted Z-values for motif AAGUGCU



Network of associatons between targets according to the STRING database.



First level regulatory network of AAGUGCU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_-_130488785 20.422 NM_009911
Cxcr4
chemokine (C-X-C motif) receptor 4
chr2_+_127161893 16.049 NM_010090
Dusp2
dual specificity phosphatase 2
chr2_+_179777187 13.624 NM_178750
Ss18l1
synovial sarcoma translocation gene on chromosome 18-like 1
chr10_+_96079634 13.126 NM_007569
Btg1
B-cell translocation gene 1, anti-proliferative
chr12_+_72116953 12.521 NM_001081195
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr11_-_34597324 12.413 NM_033374
Dock2
dedicator of cyto-kinesis 2
chr4_+_135728188 12.127 NM_177733
E2f2
E2F transcription factor 2
chr14_+_56223363 11.625 NM_001159418
Irf9
interferon regulatory factor 9
chr14_+_56222821 11.397 NM_001159417
NM_008394
Irf9

interferon regulatory factor 9

chr3_-_30868320 11.179 NM_001165954
NM_001165955
NM_001165956
NM_153421
Phc3



polyhomeotic-like 3 (Drosophila)



chr13_+_41701584 11.033 NM_001163572
Tmem170b
transmembrane protein 170B
chr8_-_73316331 10.964 NM_199308
Mast3
microtubule associated serine/threonine kinase 3
chr4_+_114732112 10.668 NM_011527
Tal1
T-cell acute lymphocytic leukemia 1
chr11_-_90252228 9.311 NM_172563
Hlf
hepatic leukemia factor
chr12_+_85792371 9.006 NM_173756
Lin52
lin-52 homolog (C. elegans)
chr4_-_133443662 8.995 NM_009097
Rps6ka1
ribosomal protein S6 kinase polypeptide 1
chr4_+_135841981 8.819 NM_009557
Zfp46
zinc finger protein 46
chr2_-_131855722 8.760 NM_175445
Rassf2
Ras association (RalGDS/AF-6) domain family member 2
chr9_+_122026378 8.257 NM_001164572
NM_133741
Snrk

SNF related kinase

chr17_+_26852581 8.133 NM_029870
A930001N09Rik
RIKEN cDNA A930001N09 gene
chr9_-_44689356 8.014 NM_001081049
Mll1
myeloid/lymphoid or mixed-lineage leukemia 1
chr11_-_86807216 7.365 NM_001005341
Ypel2
yippee-like 2 (Drosophila)
chr1_+_179374783 7.304 NM_001012330
Zfp238
zinc finger protein 238
chr19_-_14672472 7.295 NM_011600
Tle4
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr18_-_46358466 7.227 NM_001170855
Trim36
tripartite motif-containing 36
chr10_-_30522912 7.219 NM_172495
Ncoa7
nuclear receptor coactivator 7
chr17_+_25325344 7.168 NM_001197024
Unkl
unkempt-like (Drosophila)
chr5_-_44617844 7.100 NM_173764
Tapt1
transmembrane anterior posterior transformation 1
chr2_-_31939210 7.012 NM_175511
Fam78a
family with sequence similarity 78, member A
chr1_-_69732373 6.931 NM_011770
Ikzf2
IKAROS family zinc finger 2
chr5_+_37442095 6.868 NM_178394
Jakmip1
janus kinase and microtubule interacting protein 1
chr11_-_70501586 6.722 NM_001190376
NM_001190378
NM_001190379
NM_178116
Camta2



calmodulin binding transcription activator 2



chr18_+_51277551 6.663 NM_001081224
Prr16
proline rich 16
chr2_-_18919637 6.634 NM_008845
Pip4k2a
phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
chr16_-_23988680 6.530 NM_009744
Bcl6
B-cell leukemia/lymphoma 6
chr10_+_40069113 6.420 NM_001168304
NM_198164
Cdk19

cyclin-dependent kinase 19

chr18_+_32322742 6.403 NM_011946
Map3k2
mitogen-activated protein kinase kinase kinase 2
chr3_+_60305108 6.396 NM_020007
Mbnl1
muscleblind-like 1 (Drosophila)
chr5_-_64360058 6.393 NM_145923
Rell1
RELT-like 1
chr11_+_60351159 6.314 NM_172943
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chr6_-_90760116 6.205 NM_001134384
Iqsec1
IQ motif and Sec7 domain 1
chr6_-_90666474 6.081 NM_001134383
Iqsec1
IQ motif and Sec7 domain 1
chr13_-_112599181 6.012 NM_011945
Map3k1
mitogen-activated protein kinase kinase kinase 1
chr3_+_28162135 5.859 NM_001163007
NM_001163008
NM_001163009
NM_026910
Tnik



TRAF2 and NCK interacting kinase



chr5_-_138125817 5.852 NM_178162
Agfg2
ArfGAP with FG repeats 2
chr13_+_83643032 5.851 NM_001170537
NM_025282
Mef2c

myocyte enhancer factor 2C

chr6_-_116578970 5.819 NM_026057
Zfp422
zinc finger protein 422
chr10_+_42398721 5.775 NM_172416
Ostm1
osteopetrosis associated transmembrane protein 1
chr17_-_51951378 5.689 NM_001163630
Satb1
special AT-rich sequence binding protein 1
chr9_+_59598963 5.677 NM_173018
Myo9a
myosin IXa
chr5_+_139856534 5.659 NM_030258
Gpr146
G protein-coupled receptor 146
chr17_-_51971946 5.625 NM_009122
Satb1
special AT-rich sequence binding protein 1
chr17_-_51965912 5.621 NM_001163631
Satb1
special AT-rich sequence binding protein 1
chr17_-_51972514 5.590 NM_001163632
Satb1
special AT-rich sequence binding protein 1
chr9_+_7764067 5.572 NM_133739
Tmem123
transmembrane protein 123
chr11_+_97524725 5.565 NM_139311
Mllt6
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr2_+_173485260 5.565 NM_024436
Rab22a
RAB22A, member RAS oncogene family
chr17_+_25359526 5.555 NM_028789
Unkl
unkempt-like (Drosophila)
chr9_-_123760992 5.529 NM_001110253
Fyco1
FYVE and coiled-coil domain containing 1
chr17_-_31992708 5.526 NM_010831
Sik1
salt inducible kinase 1
chr4_-_128483355 5.502 NM_001081098
Zfp362
zinc finger protein 362
chr8_+_85387234 5.498 NM_177378
Rnf150
ring finger protein 150
chr6_-_28211600 5.492 NM_001081678
Zfp800
zinc finger protein 800
chr11_+_70376359 5.487 NM_001045959
NM_001045964
NM_016713
NM_176893
Mink1



misshapen-like kinase 1 (zebrafish)



chrX_-_48559008 5.330 NM_134163
Mbnl3
muscleblind-like 3 (Drosophila)
chr6_+_92041408 5.308 NM_011630
Nr2c2
nuclear receptor subfamily 2, group C, member 2
chr5_+_139865857 5.299 NM_001038703
Gpr146
G protein-coupled receptor 146
chrX_-_9046362 5.284 NM_007807
Cybb
cytochrome b-245, beta polypeptide
chr12_-_109241423 5.233 NM_001079883
NM_021399
Bcl11b

B-cell leukemia/lymphoma 11B

chr7_-_71083734 5.176 NM_021366
Klf13
Kruppel-like factor 13
chr11_-_4494815 5.078 NM_028860
Mtmr3
myotubularin related protein 3
chr16_-_92697567 5.058 NM_001111023
NM_009821
Runx1

runt related transcription factor 1

chr1_+_132613903 5.028 NM_178691
Yod1
YOD1 OTU deubiquitinating enzyme 1 homologue (S. cerevisiae)
chr16_+_55973916 4.998 NM_173026
Zbtb11
zinc finger and BTB domain containing 11
chr12_-_119539909 4.997 NM_001166385
NM_009239
Sp4

trans-acting transcription factor 4

chr3_+_103718042 4.959 NM_172684
Rsbn1
rosbin, round spermatid basic protein 1
chr18_-_46372017 4.902 NM_178872
Trim36
tripartite motif-containing 36
chr3_+_88769733 4.874 NM_138679
Ash1l
ash1 (absent, small, or homeotic)-like (Drosophila)
chr15_+_100446018 4.826 NM_011873
Dazap2
DAZ associated protein 2
chr1_-_90598670 4.805 NM_177305
Arl4c
ADP-ribosylation factor-like 4C
chr4_+_105988790 4.798 NM_183225
Usp24
ubiquitin specific peptidase 24
chr11_-_5344795 4.738 NM_001080924
Znrf3
zinc and ring finger 3
chr14_-_46277816 4.716 NM_001039106
NM_001042719
NM_176845
Ddhd1


DDHD domain containing 1


chr2_-_37286367 4.710 NM_146253
Zbtb6
zinc finger and BTB domain containing 6
chr6_-_83391623 4.699 NM_183138
Tet3
tet oncogene family member 3
chr4_-_154010868 4.691 NM_001177995
NM_027504
Prdm16

PR domain containing 16

chr13_-_54150991 4.690 NM_010076
Drd1a
dopamine receptor D1A
chr11_+_117515548 4.680 NM_198022
Tnrc6c
trinucleotide repeat containing 6C
chr11_-_69761489 4.670 NM_009204
Slc2a4
solute carrier family 2 (facilitated glucose transporter), member 4
chr2_-_153067043 4.607 NM_018807
Plagl2
pleiomorphic adenoma gene-like 2
chr8_+_3393005 4.540 NM_133962
Arhgef18
rho/rac guanine nucleotide exchange factor (GEF) 18
chr13_+_112476313 4.533 NM_172593
Mier3
mesoderm induction early response 1, family member 3
chr6_+_122770201 4.504 NM_021899
Igfbp5
Foxj2
insulin-like growth factor binding protein 5
forkhead box J2
chr17_-_43803963 4.466 NM_028711
Slc25a27
solute carrier family 25, member 27
chr1_+_133904162 4.458 NM_007923
Elk4
ELK4, member of ETS oncogene family
chr6_+_91937103 4.403 NM_172731
Fgd5
FYVE, RhoGEF and PH domain containing 5
chr19_-_4397075 4.364 NM_001001984
Kdm2a
lysine (K)-specific demethylase 2A
chr11_+_69579376 4.358 NM_029348
Zbtb4
zinc finger and BTB domain containing 4
chr10_-_30375572 4.343 NM_001111267
Ncoa7
nuclear receptor coactivator 7
chr6_-_39370351 4.318 NM_018810
Mkrn1
makorin, ring finger protein, 1
chr1_+_179375951 4.287 NM_013915
Zfp238
zinc finger protein 238
chr11_-_103128675 4.267 NM_016896
Map3k14
mitogen-activated protein kinase kinase kinase 14
chr2_+_127951773 4.191 NM_009754
NM_207680
NM_207681
Bcl2l11


BCL2-like 11 (apoptosis facilitator)


chr1_+_66515003 4.183 NM_175510
Unc80
unc-80 homolog (C. elegans)
chr13_+_43493729 4.074 NM_023554
Nol7
nucleolar protein 7
chr10_+_127896244 4.042 NM_001114096
NM_001114097
NM_198160
Smarcc2


SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2


chr11_-_88922061 4.040 NM_019505
Dgke
diacylglycerol kinase, epsilon
chr16_-_32079317 3.998 NM_177326
Pak2
p21 protein (Cdc42/Rac)-activated kinase 2
chr4_-_45024999 3.960 NM_001163283
NM_001163284
NM_173399
Zbtb5


zinc finger and BTB domain containing 5


chr4_-_44181148 3.952 NM_001038993
Rnf38
ring finger protein 38
chr2_+_22924561 3.939 NM_001102437
NM_001102438
Acbd5

acyl-Coenzyme A binding domain containing 5

chr5_-_25004598 3.906 NM_001081383
Mll3
myeloid/lymphoid or mixed-lineage leukemia 3
chr19_-_47766512 3.901 NM_007732
Col17a1
collagen, type XVII, alpha 1
chr17_+_27110101 3.860 NM_001005916
Zbtb9
zinc finger and BTB domain containing 9
chr13_-_8870975 3.732 NM_001039388
Wdr37
WD repeat domain 37
chr3_+_58810899 3.713 NM_177855
Med12l
mediator of RNA polymerase II transcription, subunit 12 homolog (yeast)-like
chr8_+_23970006 3.704 NM_001081149
Myst3
MYST histone acetyltransferase (monocytic leukemia) 3
chr15_+_80541675 3.619 NM_144812
Tnrc6b
trinucleotide repeat containing 6b
chrX_+_126284271 3.612 NM_172493
Diap2
diaphanous homolog 2 (Drosophila)
chr13_-_8870231 3.608 NM_001039389
NM_172445
Wdr37

WD repeat domain 37

chr1_-_34899878 3.607 NM_001160235
NM_001160236
NM_174997
Fam168b


family with sequence similarity 168, member B


chr2_+_32390780 3.604 NM_153560
Fam102a
family with sequence similarity 102, member A
chr4_-_126145660 3.581 NM_153403
Eif2c1
eukaryotic translation initiation factor 2C, 1
chr4_-_131978279 3.566 NM_001161797
NM_175306
Phactr4

phosphatase and actin regulator 4

chr2_+_75670230 3.556 NM_172666
Agps
alkylglycerone phosphate synthase
chr9_+_57385317 3.552 NM_001166364
NM_175273
2310046O06Rik

RIKEN cDNA 2310046O06 gene

chr5_+_148242018 3.534 NM_028291
Pan3
PAN3 polyA specific ribonuclease subunit homolog (S. cerevisiae)
chr19_+_40905768 3.529 NM_172839
Ccnj
cyclin J
chr9_-_123760686 3.477 NM_148925
Fyco1
FYVE and coiled-coil domain containing 1
chr14_+_58691522 3.465 NM_013518
Fgf9
fibroblast growth factor 9
chr2_-_33323966 3.461 NM_001025594
NM_027947
Zbtb43

zinc finger and BTB domain containing 43

chr9_-_42280256 3.441 NM_173038
Tbcel
tubulin folding cofactor E-like
chr14_+_49065971 3.428 NM_172600
6720456H20Rik
RIKEN cDNA 6720456H20 gene
chr3_+_95462640 3.421 NM_008562
Mcl1
myeloid cell leukemia sequence 1
chr7_-_74517624 3.419 NM_001033713
Mef2a
myocyte enhancer factor 2A
chr14_+_104049453 3.410 NM_198014
Slain1
SLAIN motif family, member 1
chr9_-_51976215 3.399 NM_001162921
Zc3h12c
zinc finger CCCH type containing 12C
chr2_-_7317824 3.399 NM_001110231
Celf2
CUGBP, Elav-like family member 2
chr2_+_22923653 3.369 NM_001102436
NM_028793
Acbd5

acyl-Coenzyme A binding domain containing 5

chrX_+_165233030 3.348 NM_009707
Arhgap6
Rho GTPase activating protein 6
chr17_-_88464582 3.317 NM_001081034
Fbxo11
F-box protein 11
chr5_-_138705172 3.295 NM_153161
BC037034
cDNA sequence BC037034
chrX_-_152057864 3.204 NM_001093750
Ptchd1
patched domain containing 1
chr11_+_95198329 3.178 NM_172543
Fam117a
family with sequence similarity 117, memberA
chr2_-_144096253 3.135 NM_024225
Snx5
sorting nexin 5
chr2_-_104656852 3.097 NM_001123327
Qser1
glutamine and serine rich 1
chrX_-_159326220 3.086 NM_025932
Syap1
synapse associated protein 1
chr9_-_62994774 3.044 NM_172446
NM_001163755
NM_001163757
Skor1


SKI family transcriptional corepressor 1


chr15_+_41662472 3.030 NM_001130164
Oxr1
3110047M12Rik
oxidation resistance 1
RIKEN cDNA 3110047M12 gene
chr19_+_3767420 3.028 NM_001167884
NM_001167885
NM_001167886
NM_001167887
NM_001167888
NM_001167889
NM_144871
Suv420h1






suppressor of variegation 4-20 homolog 1 (Drosophila)






chr2_+_118727248 3.026 NM_001045523
Bahd1
bromo adjacent homology domain containing 1
chr7_+_104728398 3.010 NM_001081267
Rsf1
remodeling and spacing factor 1
chr2_-_166888514 2.993 NM_001033196
Znfx1
zinc finger, NFX1-type containing 1
chr2_+_4480799 2.991 NM_001177844
Frmd4a
FERM domain containing 4A
chr11_-_51813857 2.986 NM_009458
Ube2b
ubiquitin-conjugating enzyme E2B, RAD6 homology (S. cerevisiae)
chr5_+_28643698 2.982 NM_028234
Rbm33
RNA binding motif protein 33
chr11_-_70832737 2.957 NM_033562
Derl2
Der1-like domain family, member 2
chr8_+_108583449 2.934 NM_010901
Nfatc3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr12_-_80397239 2.929 NM_001008550
Zfyve26
zinc finger, FYVE domain containing 26
chr5_-_9161670 2.924 NM_001110327
NM_011806
Dmtf1

cyclin D binding myb-like transcription factor 1

chrX_+_50265390 2.912 NM_027642
Phf6
PHD finger protein 6
chr13_-_64254466 2.889 NM_175494
Zfp367
zinc finger protein 367
chr14_+_37868015 2.851 NM_146245
Lrit1
leucine-rich repeat, immunoglobulin-like and transmembrane domains 1
chrX_+_90531783 2.848 NM_007492
Arx
aristaless related homeobox
chr5_-_96590773 2.846 NM_178854
Cnot6l
CCR4-NOT transcription complex, subunit 6-like
chr19_+_40969176 2.822 NM_028319
E130314M14Rik
Zfp518a
RIKEN cDNA E130314M14 gene
zinc finger protein 518A
chr16_-_4559511 2.781 NM_031182
Tcfap4
transcription factor AP4
chr7_-_30290470 2.762 NM_001081028
Sipa1l3
signal-induced proliferation-associated 1 like 3
chr6_-_113991945 2.719 NM_009723
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr2_-_136213509 2.712 NM_172858
Pak7
p21 protein (Cdc42/Rac)-activated kinase 7
chr9_+_121669121 2.688 NM_001166644
Zfp651
zinc finger protein 651
chr2_+_4322020 2.682 NM_001177843
Frmd4a
FERM domain containing 4A
chr12_+_4082573 2.636 NM_153082
Dnajc27
DnaJ (Hsp40) homolog, subfamily C, member 27
chr17_+_78599556 2.634 NM_015800
Crim1
cysteine rich transmembrane BMP regulator 1 (chordin like)
chr2_-_157030236 2.626 NM_001139516
NM_011249
Rbl1

retinoblastoma-like 1 (p107)

chr13_-_9764376 2.617 NM_144516
Zmynd11
zinc finger, MYND domain containing 11
chr16_-_92826307 2.590 NM_001111021
NM_001111022
Runx1

runt related transcription factor 1

chr2_+_4073908 2.589 NM_172475
Frmd4a
FERM domain containing 4A
chr2_+_49921978 2.587 NM_177139
Lypd6
LY6/PLAUR domain containing 6
chr11_+_98657082 2.585 NM_028722
Msl1
male-specific lethal 1 homolog (Drosophila)
chrX_+_165474542 2.568 NM_178754
Arhgap6
Rho GTPase activating protein 6
chr15_-_103170514 2.557 NM_013866
Zfp385a
zinc finger protein 385A
chr13_-_117814322 2.553 NM_001081009
Parp8
poly (ADP-ribose) polymerase family, member 8
chr4_-_44180323 2.551 NM_175201
Rnf38
ring finger protein 38
chr5_-_37380147 2.525 NM_011716
Wfs1
Wolfram syndrome 1 homolog (human)
chr16_-_98144201 2.491 NM_174847
C2cd2
C2 calcium-dependent domain containing 2
chr9_-_62996767 2.485 NM_001163758
Skor1
SKI family transcriptional corepressor 1
chr6_-_116143380 2.482 NM_177412
Tmcc1
transmembrane and coiled coil domains 1
chr6_+_114593104 2.465 NM_028835
Atg7
autophagy-related 7 (yeast)
chr12_-_73337707 2.442 NM_001007596
Rtn1
reticulon 1
chr5_-_144493077 2.432 NM_029749
Usp42
ubiquitin specific peptidase 42
chr4_+_59818521 2.430 NM_172468
Snx30
sorting nexin family member 30
chr12_+_54349663 2.389 NM_013780
Npas3
neuronal PAS domain protein 3
chr6_+_53989925 2.388 NM_001163640
Chn2
chimerin (chimaerin) 2
chr13_+_14156038 2.335 NM_194262
NM_198122
Arid4b

AT rich interactive domain 4B (RBP1-like)

chr15_+_80629020 2.328 NM_177124
Tnrc6b
trinucleotide repeat containing 6b
chr9_-_119488133 2.310 NM_021544
Scn5a
sodium channel, voltage-gated, type V, alpha
chr10_-_114238419 2.302 NM_146241
Trhde
TRH-degrading enzyme
chr2_-_6805937 2.286 NM_001110228
NM_001160293
NM_010160
Celf2


CUGBP, Elav-like family member 2


chr10_+_13686174 2.268 NM_010437
Hivep2
human immunodeficiency virus type I enhancer binding protein 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.89 1.46e-25 GO:0051252 regulation of RNA metabolic process
2.90 3.61e-25 GO:0006355 regulation of transcription, DNA-dependent
3.27 1.20e-24 GO:0006351 transcription, DNA-dependent
3.26 1.39e-24 GO:0032774 RNA biosynthetic process
2.68 1.94e-24 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.75 4.40e-24 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.68 4.81e-24 GO:0010468 regulation of gene expression
2.65 5.32e-24 GO:0051171 regulation of nitrogen compound metabolic process
2.41 1.08e-23 GO:0060255 regulation of macromolecule metabolic process
2.70 1.20e-23 GO:0010556 regulation of macromolecule biosynthetic process
2.34 1.22e-22 GO:0080090 regulation of primary metabolic process
2.60 1.70e-22 GO:0031326 regulation of cellular biosynthetic process
2.32 2.58e-22 GO:0031323 regulation of cellular metabolic process
2.56 5.53e-22 GO:0009889 regulation of biosynthetic process
2.16 1.24e-20 GO:0019222 regulation of metabolic process
2.60 1.42e-18 GO:0016070 RNA metabolic process
2.43 8.90e-18 GO:0090304 nucleic acid metabolic process
2.54 1.03e-17 GO:0034645 cellular macromolecule biosynthetic process
2.52 1.97e-17 GO:0009059 macromolecule biosynthetic process
1.95 5.85e-17 GO:0044260 cellular macromolecule metabolic process
2.20 6.77e-16 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.35 4.88e-15 GO:0010467 gene expression
2.05 4.55e-14 GO:0034641 cellular nitrogen compound metabolic process
1.80 5.76e-14 GO:0043170 macromolecule metabolic process
2.02 1.50e-13 GO:0006807 nitrogen compound metabolic process
2.10 3.47e-13 GO:0009058 biosynthetic process
2.11 7.33e-13 GO:0044249 cellular biosynthetic process
1.63 1.12e-11 GO:0044237 cellular metabolic process
1.59 9.72e-11 GO:0044238 primary metabolic process
2.99 1.90e-09 GO:0006357 regulation of transcription from RNA polymerase II promoter
3.42 4.29e-09 GO:0010629 negative regulation of gene expression
1.48 2.05e-08 GO:0008152 metabolic process
3.44 4.37e-08 GO:0045892 negative regulation of transcription, DNA-dependent
3.39 6.84e-08 GO:0051253 negative regulation of RNA metabolic process
3.15 1.03e-07 GO:0010558 negative regulation of macromolecule biosynthetic process
3.20 1.12e-07 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.98 5.69e-07 GO:0009890 negative regulation of biosynthetic process
2.98 9.71e-07 GO:0031327 negative regulation of cellular biosynthetic process
3.08 1.03e-06 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.03 1.57e-06 GO:0051172 negative regulation of nitrogen compound metabolic process
1.41 2.51e-06 GO:0050794 regulation of cellular process
3.60 6.75e-06 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.49 2.90e-05 GO:0010605 negative regulation of macromolecule metabolic process
3.80 6.01e-05 GO:0016568 chromatin modification
2.55 7.37e-05 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.66 7.95e-05 GO:0051254 positive regulation of RNA metabolic process
1.34 1.02e-04 GO:0050789 regulation of biological process
2.36 1.05e-04 GO:0009892 negative regulation of metabolic process
2.49 1.43e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
2.63 1.64e-04 GO:0045893 positive regulation of transcription, DNA-dependent
2.39 1.97e-04 GO:0031324 negative regulation of cellular metabolic process
2.48 4.64e-04 GO:0010628 positive regulation of gene expression
1.31 5.56e-04 GO:0065007 biological regulation
3.32 7.01e-04 GO:0006325 chromatin organization
1.65 1.54e-03 GO:0007275 multicellular organismal development
2.28 1.84e-03 GO:0031328 positive regulation of cellular biosynthetic process
2.43 2.21e-03 GO:0045595 regulation of cell differentiation
1.72 2.29e-03 GO:0048731 system development
1.60 2.42e-03 GO:0032502 developmental process
1.77 2.57e-03 GO:0048523 negative regulation of cellular process
1.67 2.74e-03 GO:0048856 anatomical structure development
2.24 2.96e-03 GO:0009891 positive regulation of biosynthetic process
2.03 3.54e-03 GO:0010604 positive regulation of macromolecule metabolic process
1.71 4.30e-03 GO:0048519 negative regulation of biological process
1.96 4.63e-03 GO:0006996 organelle organization
1.78 4.83e-03 GO:0048869 cellular developmental process
2.26 5.65e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
2.00 5.84e-03 GO:0031325 positive regulation of cellular metabolic process
1.95 6.47e-03 GO:0009893 positive regulation of metabolic process
1.77 7.45e-03 GO:0030154 cell differentiation
1.66 9.07e-03 GO:0048522 positive regulation of cellular process
1.84 1.23e-02 GO:0006464 protein modification process
2.24 1.72e-02 GO:0022008 neurogenesis
2.64 2.05e-02 GO:0051276 chromosome organization
2.51 2.20e-02 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.78 2.40e-02 GO:0043412 macromolecule modification
2.25 3.00e-02 GO:0048699 generation of neurons
1.75 4.18e-02 GO:0048513 organ development
19.17 4.60e-02 GO:0035162 embryonic hemopoiesis

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.91 4.58e-18 GO:0005634 nucleus
1.44 7.26e-12 GO:0043229 intracellular organelle
1.43 1.06e-11 GO:0043226 organelle
1.36 1.41e-11 GO:0005622 intracellular
1.36 3.60e-11 GO:0044424 intracellular part
1.44 8.72e-10 GO:0043231 intracellular membrane-bounded organelle
1.44 1.09e-09 GO:0043227 membrane-bounded organelle
2.02 1.38e-04 GO:0031981 nuclear lumen
2.59 1.75e-04 GO:0044451 nucleoplasm part
1.87 3.11e-04 GO:0044428 nuclear part
1.85 9.63e-04 GO:0070013 intracellular organelle lumen
1.85 1.02e-03 GO:0043233 organelle lumen
2.13 1.39e-03 GO:0005654 nucleoplasm
1.81 1.86e-03 GO:0031974 membrane-enclosed lumen
1.13 3.12e-03 GO:0005623 cell
1.13 3.12e-03 GO:0044464 cell part
6.88 4.10e-02 GO:0017053 transcriptional repressor complex

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
2.46 1.65e-18 GO:0003676 nucleic acid binding
2.86 2.06e-18 GO:0003677 DNA binding
1.40 5.43e-14 GO:0005488 binding
2.83 4.16e-13 GO:0008270 zinc ion binding
2.46 1.11e-10 GO:0046914 transition metal ion binding
1.89 3.36e-10 GO:0046872 metal ion binding
1.87 7.38e-10 GO:0043169 cation binding
3.24 9.38e-10 GO:0001071 nucleic acid binding transcription factor activity
3.24 9.38e-10 GO:0003700 sequence-specific DNA binding transcription factor activity
1.86 9.42e-10 GO:0043167 ion binding
2.88 1.06e-08 GO:0030528 transcription regulator activity
2.75 4.33e-05 GO:0043565 sequence-specific DNA binding
3.37 6.36e-04 GO:0016564 transcription repressor activity
3.20 1.41e-03 GO:0016563 transcription activator activity
2.24 1.94e-03 GO:0019899 enzyme binding
39.54 6.92e-03 GO:0070579 methylcytosine dioxygenase activity
2.75 8.10e-03 GO:0004674 protein serine/threonine kinase activity
7.24 1.21e-02 GO:0042826 histone deacetylase binding
1.33 2.01e-02 GO:0005515 protein binding
10.14 2.93e-02 GO:0018024 histone-lysine N-methyltransferase activity
2.17 3.85e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
9.42 4.24e-02 GO:0016278 lysine N-methyltransferase activity
9.42 4.24e-02 GO:0016279 protein-lysine N-methyltransferase activity