Motif ID: ACAGUAU

Z-value: 0.604


Mature miRNA associated with seed ACAGUAU:

NamemiRBase Accession
mmu-miR-144 MIMAT0000156



Activity profile for motif ACAGUAU.

activity profile for motif ACAGUAU


Sorted Z-values histogram for motif ACAGUAU

Sorted Z-values for motif ACAGUAU



Network of associatons between targets according to the STRING database.



First level regulatory network of ACAGUAU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_121558695 6.263 NM_011055
 Pde3b
phosphodiesterase 3B, cGMP-inhibited
chr15_+_7090525 4.350 NM_013584
 Lifr
leukemia inhibitory factor receptor
chr12_+_82127791 3.919 NM_001146217
NM_022316
 Smoc1

SPARC related modular calcium binding 1

chr1_-_82287990 3.876 NM_010570
 Irs1
insulin receptor substrate 1
chr15_+_68758773 3.562 NM_010158
 Khdrbs3
KH domain containing, RNA binding, signal transduction associated 3
chr14_-_17407701 3.322 NM_011243
 Rarb
retinoic acid receptor, beta
chr15_+_85566122 3.258 NM_011144
 Ppara
peroxisome proliferator activated receptor alpha
chr3_+_52072251 3.141 NM_019739
 Foxo1
forkhead box O1
chr15_+_85565935 3.031 NM_001113418
 Ppara
peroxisome proliferator activated receptor alpha
chr1_-_166388431 2.946 NM_009721
 Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr13_-_115248924 2.944 NM_008046
 Fst
follistatin
chr4_-_131631226 2.875 NM_001128607
 Epb4.1
erythrocyte protein band 4.1
chr2_-_115890247 2.837 NM_001159569
NM_001159570
 Meis2

Meis homeobox 2

chr8_-_105308910 2.759 NM_009866
 Cdh11
cadherin 11
chr2_-_115890747 2.751 NM_001136072
NM_001159567
NM_001159568
NM_010825
 Meis2



Meis homeobox 2



chr5_+_15440508 2.716 NM_001110843
NM_001110844
NM_001110845
NM_001110846
NM_009784
 Cacna2d1




calcium channel, voltage-dependent, alpha2/delta subunit 1




chr4_-_131628011 2.673 NM_183428
 Epb4.1
erythrocyte protein band 4.1
chr13_+_109444370 2.593 NM_011056
 Pde4d
phosphodiesterase 4D, cAMP specific
chr4_+_132567420 2.551 NM_146155
 Ahdc1
AT hook, DNA binding motif, containing 1
chr18_+_64500017 2.488 NM_194268
 Onecut2
one cut domain, family member 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 110 entries
Enrichment   P-value GO Accession GO Term
6.59 1.14e-04 GO:0048736 appendage development
6.59 1.14e-04 GO:0060173 limb development
6.29 6.02e-04 GO:0035107 appendage morphogenesis
6.29 6.02e-04 GO:0035108 limb morphogenesis
5.49 4.96e-02 GO:0030326 embryonic limb morphogenesis
5.49 4.96e-02 GO:0035113 embryonic appendage morphogenesis
4.40 2.31e-03 GO:0030900 forebrain development
4.23 3.83e-03 GO:0043193 positive regulation of gene-specific transcription
4.07 1.25e-02 GO:0048732 gland development
3.64 9.23e-04 GO:0007167 enzyme linked receptor protein signaling pathway
3.60 5.95e-04 GO:0009968 negative regulation of signal transduction
3.56 2.06e-04 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
3.56 4.70e-03 GO:0035295 tube development
3.48 4.22e-06 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
3.46 6.90e-03 GO:0007420 brain development
3.45 6.65e-04 GO:0010648 negative regulation of cell communication
3.38 9.60e-03 GO:0007423 sensory organ development
3.34 1.13e-03 GO:0048598 embryonic morphogenesis
3.30 2.45e-03 GO:0023057 negative regulation of signaling
3.29 1.49e-07 GO:0051254 positive regulation of RNA metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 15 of 15 entries
Enrichment   P-value GO Accession GO Term
2.34 2.20e-02 GO:0044451 nucleoplasm part
2.04 2.89e-02 GO:0005654 nucleoplasm
1.88 6.79e-14 GO:0005634 nucleus
1.88 1.41e-02 GO:0031981 nuclear lumen
1.84 4.75e-03 GO:0044428 nuclear part
1.64 4.81e-03 GO:0043234 protein complex
1.56 6.84e-03 GO:0032991 macromolecular complex
1.44 1.02e-07 GO:0043231 intracellular membrane-bounded organelle
1.43 1.23e-07 GO:0043227 membrane-bounded organelle
1.34 1.39e-08 GO:0005622 intracellular
1.34 5.41e-08 GO:0044424 intracellular part
1.32 5.43e-05 GO:0043229 intracellular organelle
1.32 6.85e-05 GO:0043226 organelle
1.14 3.57e-03 GO:0005623 cell
1.14 3.57e-03 GO:0044464 cell part

Gene overrepresentation in function category:

Showing 1 to 20 of 22 entries
Enrichment   P-value GO Accession GO Term
21.12 7.77e-03 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity
7.61 3.70e-02 GO:0003707 steroid hormone receptor activity
7.46 4.14e-02 GO:0004879 ligand-dependent nuclear receptor activity
4.23 4.24e-06 GO:0016563 transcription activator activity
3.85 1.76e-04 GO:0016564 transcription repressor activity
3.69 6.27e-04 GO:0008134 transcription factor binding
3.64 1.19e-10 GO:0001071 nucleic acid binding transcription factor activity
3.64 1.19e-10 GO:0003700 sequence-specific DNA binding transcription factor activity
3.51 3.46e-08 GO:0043565 sequence-specific DNA binding
3.11 1.11e-08 GO:0030528 transcription regulator activity
2.72 1.62e-09 GO:0008270 zinc ion binding
2.72 6.91e-03 GO:0019904 protein domain specific binding
2.51 4.00e-10 GO:0003677 DNA binding
2.47 2.43e-15 GO:0003676 nucleic acid binding
2.35 1.99e-07 GO:0046914 transition metal ion binding
2.31 2.77e-02 GO:0003723 RNA binding
1.92 6.26e-09 GO:0043169 cation binding
1.91 7.76e-09 GO:0043167 ion binding
1.90 1.82e-08 GO:0046872 metal ion binding
1.73 8.39e-03 GO:0000166 nucleotide binding