Motif ID: ACCCUGU

Z-value: 0.581


Mature miRNA associated with seed ACCCUGU:

NamemiRBase Accession
mmu-miR-10a MIMAT0000648
mmu-miR-10b MIMAT0000208



Activity profile for motif ACCCUGU.

activity profile for motif ACCCUGU


Sorted Z-values histogram for motif ACCCUGU

Sorted Z-values for motif ACCCUGU



Network of associatons between targets according to the STRING database.



First level regulatory network of ACCCUGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr4_-_91066674 7.339 NM_207685
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr4_-_91042997 6.897 NM_001177883
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr4_-_91038729 6.793 NM_010486
NM_207686
Elavl2

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)

chr1_+_155500166 4.980 NM_026380
Rgs8
regulator of G-protein signaling 8
chr12_+_30219769 4.675 NM_001093776
Myt1l
myelin transcription factor 1-like
chr11_-_36757743 4.457 NM_011856
Odz2
odd Oz/ten-m homolog 2 (Drosophila)
chr12_+_30213224 4.299 NM_001093775
NM_001093778
NM_008666
Myt1l


myelin transcription factor 1-like


chr11_+_42233258 4.248 NM_008070
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr11_+_98769464 4.214 NM_011799
Cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr11_+_98769162 4.113 NM_001025779
Cdc6
cell division cycle 6 homolog (S. cerevisiae)
chr13_+_118391126 3.683 NM_010408
Hcn1
hyperpolarization-activated, cyclic nucleotide-gated K+ 1
chr2_+_65683823 3.407 NM_153409
NM_178634
Csrnp3

cysteine-serine-rich nuclear protein 3

chr1_-_134603848 3.246 NM_001160318
Nfasc
neurofascin
chr4_+_32504409 3.167 NM_001109661
Bach2
BTB and CNC homology 2
chr1_-_134539434 3.118 NM_001160316
Nfasc
neurofascin
chr12_-_68323528 2.977 NM_001193266
NM_207010
Mdga2

MAM domain containing glycosylphosphatidylinositol anchor 2

chr9_+_72655019 2.754 NM_175485
Prtg
protogenin homolog (Gallus gallus)
chr6_-_113145321 2.746 NM_177763
Lhfpl4
lipoma HMGIC fusion partner-like protein 4
chr9_+_21001148 2.733 NM_019798
Pde4a
phosphodiesterase 4A, cAMP specific
chr10_+_4795808 2.586 NM_153399
Syne1
synaptic nuclear envelope 1
chr5_-_84846348 2.578 NM_007937
Epha5
Eph receptor A5
chr6_+_103460834 2.514 NM_007697
Chl1
cell adhesion molecule with homology to L1CAM
chr10_-_42894259 2.458 NM_175407
Sobp
sine oculis-binding protein homolog (Drosophila)
chr11_-_5965743 2.397 NM_001174053
NM_001174054
NM_007595
Camk2b


calcium/calmodulin-dependent protein kinase II, beta


chr1_-_134638361 2.329 NM_001160317
NM_182716
Nfasc

neurofascin

chr7_-_116651647 2.268 NM_001170912
NM_181853
Trim66

tripartite motif-containing 66

chr7_-_116637251 2.222 NM_001170913
Trim66
tripartite motif-containing 66
chr18_-_24688688 1.957 NM_144861
Rprd1a
regulation of nuclear pre-mRNA domain containing 1A
chr4_+_57580989 1.918 NM_172868
Palm2
paralemmin 2
chr8_-_17535279 1.895 NM_053171
Csmd1
CUB and Sushi multiple domains 1
chr1_-_63160764 1.857 NM_001081436
NM_001114609
Ino80d

INO80 complex subunit D

chr18_-_77803843 1.797 NM_001164504
8030462N17Rik
Rnf165
RIKEN cDNA 8030462N17 gene
ring finger protein 165
chr14_-_55482884 1.789 NM_001177705
Homez
homeodomain leucine zipper-encoding gene
chr6_-_120443824 1.777 NM_033567
Cecr6
cat eye syndrome chromosome region, candidate 6 homolog (human)
chr11_-_118074052 1.761 NM_001112700
Cyth1
cytohesin 1
chr5_+_97426665 1.727 NM_080708
Bmp2k
BMP2 inducible kinase
chr9_+_20970150 1.725 NM_183408
Pde4a
phosphodiesterase 4A, cAMP specific
chr17_+_31194623 1.627 NM_009593
Abcg1
ATP-binding cassette, sub-family G (WHITE), member 1
chr10_+_110182506 1.622 NM_178609
E2f7
E2F transcription factor 7
chr15_+_80629020 1.621 NM_177124
Tnrc6b
trinucleotide repeat containing 6b
chr13_+_41701584 1.617 NM_001163572
Tmem170b
transmembrane protein 170B
chr19_-_5118229 1.617 NM_008451
Klc2
kinesin light chain 2
chr12_-_81861527 1.591 NM_001008423
Gm1568
predicted gene 1568
chr19_-_58935470 1.569 NM_175199
Hspa12a
heat shock protein 12A
chr14_-_55479326 1.569 NM_183174
Homez
homeodomain leucine zipper-encoding gene
chr19_+_32832002 1.566 NM_008960
Pten
phosphatase and tensin homolog
chr8_+_109394141 1.553 NM_008217
Has3
hyaluronan synthase 3
chr11_-_103611082 1.517 NM_011719
Wnt9b
wingless-type MMTV integration site 9B
chr2_+_172375092 1.508 NM_009335
Tcfap2c
transcription factor AP-2, gamma
chr11_-_118109789 1.442 NM_001112699
NM_011180
Cyth1

cytohesin 1

chr15_+_80541675 1.400 NM_144812
Tnrc6b
trinucleotide repeat containing 6b
chr1_+_64579358 1.334 NM_001037726
NM_009952
NM_133828
Creb1


cAMP responsive element binding protein 1


chr2_-_7317824 1.233 NM_001110231
Celf2
CUGBP, Elav-like family member 2
chr1_-_67085404 1.216 NM_001190984
NM_001190985
NM_021295
Lancl1


LanC (bacterial lantibiotic synthetase component C)-like 1


chr6_-_126690651 1.139 NM_013568
Kcna6
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr11_+_74433092 1.138 NM_001013784
E130309D14Rik
RIKEN cDNA E130309D14 gene
chr19_+_45438212 1.134 NM_001037758
NM_009771
Btrc

beta-transducin repeat containing protein

chr2_+_172376490 1.086 NM_001159696
Tcfap2c
transcription factor AP-2, gamma
chr19_-_19075535 1.082 NM_146095
Rorb
RAR-related orphan receptor beta
chr8_+_109817355 1.027 NM_018823
NM_133957
Nfat5

nuclear factor of activated T-cells 5

chr17_-_66426361 0.986 NM_001025572
Ankrd12
ankyrin repeat domain 12
chr19_-_19185685 0.977 NM_001043354
Rorb
RAR-related orphan receptor beta
chr2_-_65405546 0.957 NM_018732
Scn3a
sodium channel, voltage-gated, type III, alpha
chr7_-_135883942 0.847 NM_145955
Mcmbp
MCM (minichromosome maintenance deficient) binding protein
chr11_-_115885714 0.837 NM_008211
H3f3b
H3 histone, family 3B
chr4_-_136512727 0.798 NM_007939
Epha8
Eph receptor A8
chr9_-_108551631 0.794 NM_011790
Arih2
ariadne homolog 2 (Drosophila)
chr2_-_38640034 0.793 NM_001159548
NM_001159549
Nr6a1

nuclear receptor subfamily 6, group A, member 1

chr6_+_92041408 0.776 NM_011630
Nr2c2
nuclear receptor subfamily 2, group C, member 2
chr2_-_6805937 0.727 NM_001110228
NM_001160293
NM_010160
Celf2


CUGBP, Elav-like family member 2


chr2_+_109514856 0.694 NM_007540
Bdnf
brain derived neurotrophic factor
chr1_-_157820378 0.636 NM_001039184
Cep350
centrosomal protein 350
chr7_-_142129892 0.609 NM_001143802
Fam196a
family with sequence similarity 196, member A
chrX_-_47150892 0.593 NM_177591
NM_177915
Igsf1

immunoglobulin superfamily, member 1

chr16_+_32332294 0.559 NM_177633
Ubxn7
UBX domain protein 7
chr3_-_104315778 0.539 NM_001025067
Lrig2
leucine-rich repeats and immunoglobulin-like domains 2
chr6_+_90319485 0.539 NM_030260
NM_173002
Zxdc

ZXD family zinc finger C

chr4_+_21703416 0.530 NM_152825
Usp45
ubiquitin specific petidase 45
chr15_+_84753817 0.524 NM_016714
Nup50
nucleoporin 50
chr2_-_59963796 0.516 NM_001001182
Baz2b
bromodomain adjacent to zinc finger domain, 2B
chr11_+_93857338 0.502 NM_027569
Spag9
sperm associated antigen 9
chr14_+_120877548 0.491 NM_029519
Rap2a
RAS related protein 2a
chr4_+_148919218 0.449 NM_001141930
Ctnnbip1
catenin beta interacting protein 1
chr7_+_54051432 0.424 NM_008186
Gtf2h1
general transcription factor II H, polypeptide 1
chr6_-_126595818 0.419 NM_010595
Kcna1
potassium voltage-gated channel, shaker-related subfamily, member 1
chr2_+_109532592 0.418 NM_001048141
Bdnf
brain derived neurotrophic factor
chr13_+_44826121 0.413 NM_021878
Jarid2
jumonji, AT rich interactive domain 2
chr14_-_21613162 0.385 NM_001039138
NM_001039139
NM_178597
Camk2g


calcium/calmodulin-dependent protein kinase II gamma


chr4_+_148892231 0.383 NM_023465
Ctnnbip1
catenin beta interacting protein 1
chr16_-_23988680 0.333 NM_009744
Bcl6
B-cell leukemia/lymphoma 6
chr2_-_168427037 0.320 NM_001037178
Nfatc2
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2
chr14_+_49065971 0.315 NM_172600
6720456H20Rik
RIKEN cDNA 6720456H20 gene
chr5_+_135663096 0.293 NM_011714
Baz1b
bromodomain adjacent to zinc finger domain, 1B
chr14_+_29831283 0.273 NM_176920
Lrtm1
leucine-rich repeats and transmembrane domains 1
chr2_+_32462471 0.228 NM_001025310
NM_016973
St6galnac6

ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6

chr2_+_32455168 0.222 NM_001025311
St6galnac6
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr1_-_138856866 0.219 NM_030676
Nr5a2
nuclear receptor subfamily 5, group A, member 2
chr2_+_109533719 0.168 NM_001048142
Bdnf
brain derived neurotrophic factor
chr16_+_33251485 0.109 NM_080557
Snx4
sorting nexin 4
chr13_-_30077931 0.079 NM_010093
E2f3
E2F transcription factor 3
chr5_-_125659422 0.064 NM_011424
Ncor2
nuclear receptor co-repressor 2
chr4_-_132478424 0.064 NM_001163792
NM_145553
Fam76a

family with sequence similarity 76, member A

chr11_+_79153388 0.043 NM_010897
Nf1
neurofibromatosis 1
chr5_+_120284671 0.022 NM_011537
Tbx5
T-box 5
chr1_-_138850206 0.013 NM_001159769
Nr5a2
nuclear receptor subfamily 5, group A, member 2
chr11_+_72503487 0.011 NM_009671
Ankfy1
ankyrin repeat and FYVE domain containing 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.91 8.91e-05 GO:0006355 regulation of transcription, DNA-dependent
2.85 1.34e-04 GO:0051252 regulation of RNA metabolic process
2.77 1.35e-04 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.65 2.01e-04 GO:0031326 regulation of cellular biosynthetic process
2.70 2.26e-04 GO:0010556 regulation of macromolecule biosynthetic process
2.61 2.63e-04 GO:0009889 regulation of biosynthetic process
2.62 4.35e-04 GO:0010468 regulation of gene expression
2.57 6.23e-04 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.55 7.69e-04 GO:0051171 regulation of nitrogen compound metabolic process
3.00 1.92e-03 GO:0006351 transcription, DNA-dependent
3.00 1.98e-03 GO:0032774 RNA biosynthetic process
2.27 2.07e-03 GO:0060255 regulation of macromolecule metabolic process
2.11 2.86e-03 GO:0019222 regulation of metabolic process
3.30 3.00e-03 GO:0009653 anatomical structure morphogenesis
3.84 3.51e-03 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.19 4.28e-03 GO:0080090 regulation of primary metabolic process
2.17 4.97e-03 GO:0031323 regulation of cellular metabolic process
4.23 5.58e-03 GO:0045893 positive regulation of transcription, DNA-dependent
4.17 6.55e-03 GO:0051254 positive regulation of RNA metabolic process
4.14 7.05e-03 GO:0045595 regulation of cell differentiation
2.50 8.05e-03 GO:0034645 cellular macromolecule biosynthetic process
2.47 9.26e-03 GO:0009059 macromolecule biosynthetic process
1.92 1.12e-02 GO:0044260 cellular macromolecule metabolic process
3.89 1.39e-02 GO:0010628 positive regulation of gene expression
50.27 1.44e-02 GO:0001953 negative regulation of cell-matrix adhesion
2.40 1.53e-02 GO:0048522 positive regulation of cellular process
3.58 1.64e-02 GO:0009891 positive regulation of biosynthetic process
3.69 2.34e-02 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.39 2.55e-02 GO:0048731 system development
3.64 2.72e-02 GO:0010557 positive regulation of macromolecule biosynthetic process
2.25 2.96e-02 GO:0048518 positive regulation of biological process
3.88 2.99e-02 GO:0048699 generation of neurons
2.20 3.01e-02 GO:0007275 multicellular organismal development
3.38 3.01e-02 GO:0050793 regulation of developmental process
3.60 3.03e-02 GO:0051173 positive regulation of nitrogen compound metabolic process
19.16 3.05e-02 GO:0043401 steroid hormone mediated signaling pathway
3.19 3.13e-02 GO:0007399 nervous system development
2.55 3.66e-02 GO:0030154 cell differentiation
2.10 4.67e-02 GO:0032502 developmental process
2.24 4.89e-02 GO:0048856 anatomical structure development

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.94 4.92e-04 GO:0005634 nucleus
4.24 1.13e-02 GO:0043005 neuron projection

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
5.46 9.05e-07 GO:0001071 nucleic acid binding transcription factor activity
5.46 9.05e-07 GO:0003700 sequence-specific DNA binding transcription factor activity
4.46 1.38e-03 GO:0043565 sequence-specific DNA binding
1.75 5.04e-03 GO:0005515 protein binding
18.77 5.97e-03 GO:0003707 steroid hormone receptor activity
18.41 6.45e-03 GO:0004879 ligand-dependent nuclear receptor activity
3.48 7.70e-03 GO:0030528 transcription regulator activity
2.20 1.71e-02 GO:0003676 nucleic acid binding
2.50 2.15e-02 GO:0003677 DNA binding
6.94 2.23e-02 GO:0003682 chromatin binding
4.99 5.00e-02 GO:0016563 transcription activator activity