Motif ID: AGCACCA

Z-value: 2.379


Mature miRNA associated with seed AGCACCA:

NamemiRBase Accession
mmu-miR-29a MIMAT0000535
mmu-miR-29b MIMAT0000127
mmu-miR-29c MIMAT0000536



Activity profile for motif AGCACCA.

activity profile for motif AGCACCA


Sorted Z-values histogram for motif AGCACCA

Sorted Z-values for motif AGCACCA



Network of associatons between targets according to the STRING database.



First level regulatory network of AGCACCA

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_55233581 60.347 NM_009242
 Sparc
secreted acidic cysteine rich glycoprotein
chr16_+_37777075 50.340 NM_008047
 Fstl1
follistatin-like 1
chr18_-_33623668 46.023 NM_001109988
 D0H4S114
DNA segment, human D4S114
chr18_-_33623400 45.491 NM_001109989
 D0H4S114
DNA segment, human D4S114
chr18_-_33623069 44.678 NM_001109990
 D0H4S114
DNA segment, human D4S114
chr18_-_33623287 44.221 NM_053078
 D0H4S114
DNA segment, human D4S114
chr6_+_4455686 43.404 NM_007743
 Col1a2
collagen, type I, alpha 2
chr8_-_11312729 40.403 NM_009931
 Col4a1
collagen, type IV, alpha 1
chr7_-_106501642 40.205 NM_001111043
NM_001111044
NM_009825
 Serpinh1


serine (or cysteine) peptidase inhibitor, clade H, member 1


chr8_+_95351212 39.759 NM_008610
 Mmp2
matrix metallopeptidase 2
chr8_+_11312828 37.407 NM_009932
 Col4a2
collagen, type IV, alpha 2
chr1_+_45368382 35.292 NM_009930
 Col3a1
collagen, type III, alpha 1
chr1_-_45560001 35.080 NM_007737
 Col5a2
collagen, type V, alpha 2
chr12_+_30622876 33.854 NM_181395
 Pxdn
peroxidasin homolog (Drosophila)
chr6_+_30688050 33.697 NM_008590
 Mest
mesoderm specific transcript
chr3_+_67868723 30.150 NM_001113420
NM_001113421
 Schip1

schwannomin interacting protein 1

chr3_+_113733457 29.917 NM_007729
 Col11a1
collagen, type XI, alpha 1
chr4_+_140566338 27.357 NM_001161799
 Mfap2
microfibrillar-associated protein 2
chr18_-_53577625 27.286 NM_008908
 Ppic
peptidylprolyl isomerase C
chr4_+_115894518 26.583 NM_181585
 Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 46 entries
Enrichment   P-value GO Accession GO Term
14.91 4.86e-05 GO:0030199 collagen fibril organization
9.46 2.27e-03 GO:0043588 skin development
7.27 6.98e-08 GO:0030198 extracellular matrix organization
6.42 1.47e-02 GO:0045667 regulation of osteoblast differentiation
5.85 1.17e-07 GO:0043062 extracellular structure organization
4.81 2.64e-02 GO:0001822 kidney development
4.68 3.39e-02 GO:0072001 renal system development
4.12 2.50e-02 GO:0001655 urogenital system development
3.76 3.27e-04 GO:0001501 skeletal system development
3.17 1.51e-02 GO:0001568 blood vessel development
3.13 7.93e-07 GO:0007155 cell adhesion
3.10 1.01e-06 GO:0022610 biological adhesion
3.06 1.48e-02 GO:0001944 vasculature development
3.01 1.12e-02 GO:0022603 regulation of anatomical structure morphogenesis
2.95 2.09e-04 GO:0072358 cardiovascular system development
2.95 2.09e-04 GO:0072359 circulatory system development
2.93 1.75e-02 GO:0007167 enzyme linked receptor protein signaling pathway
2.80 3.42e-02 GO:0016477 cell migration
2.75 4.35e-02 GO:0009968 negative regulation of signal transduction
2.74 4.71e-02 GO:0051093 negative regulation of developmental process

Gene overrepresentation in compartment category:

Showing 1 to 19 of 19 entries
Enrichment   P-value GO Accession GO Term
48.47 1.60e-08 GO:0005587 collagen type IV
48.47 1.60e-08 GO:0030935 sheet-forming collagen
48.47 1.88e-03 GO:0005588 collagen type V
31.69 8.92e-21 GO:0005581 collagen
29.83 7.72e-09 GO:0005583 fibrillar collagen
24.23 3.59e-02 GO:0001527 microfibril
12.84 1.51e-23 GO:0044420 extracellular matrix part
11.97 3.86e-14 GO:0005604 basement membrane
7.17 1.52e-21 GO:0005578 proteinaceous extracellular matrix
6.60 3.73e-21 GO:0031012 extracellular matrix
5.05 6.23e-03 GO:0016327 apicolateral plasma membrane
4.64 3.01e-02 GO:0043296 apical junction complex
3.18 1.87e-02 GO:0005911 cell-cell junction
2.67 3.36e-08 GO:0044421 extracellular region part
2.54 3.12e-04 GO:0030054 cell junction
1.83 3.18e-04 GO:0044459 plasma membrane part
1.78 1.04e-03 GO:0005576 extracellular region
1.66 8.36e-07 GO:0005886 plasma membrane
1.64 1.45e-06 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
28.41 1.79e-19 GO:0005201 extracellular matrix structural constituent
28.27 3.01e-07 GO:0048407 platelet-derived growth factor binding
16.16 2.14e-02 GO:0005161 platelet-derived growth factor receptor binding
4.62 1.73e-02 GO:0019838 growth factor binding
3.52 2.59e-06 GO:0005198 structural molecule activity
1.53 5.42e-08 GO:0005515 protein binding
1.23 1.95e-04 GO:0005488 binding