Motif ID: AGUGGUU

Z-value: 0.956


Mature miRNA associated with seed AGUGGUU:

NamemiRBase Accession
mmu-miR-140 MIMAT0000151
mmu-miR-876-3p MIMAT0004855



Activity profile for motif AGUGGUU.

activity profile for motif AGUGGUU


Sorted Z-values histogram for motif AGUGGUU

Sorted Z-values for motif AGUGGUU



Network of associatons between targets according to the STRING database.



First level regulatory network of AGUGGUU

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_75552144 18.449 NM_001083316
 Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr2_-_91864276 17.818 NM_011957
 Creb3l1
cAMP responsive element binding protein 3-like 1
chr4_+_57867433 13.642 NM_001035533
 Akap2
A kinase (PRKA) anchor protein 2
chr5_+_75548309 12.988 NM_011058
 Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr4_+_57858096 12.893 NM_001035532
NM_009649
 Akap2

A kinase (PRKA) anchor protein 2

chr1_-_72921438 12.463 NM_010518
 Igfbp5
insulin-like growth factor binding protein 5
chr2_-_125332107 12.338 NM_007993
 Fbn1
fibrillin 1
chr7_-_96666081 12.095 NM_029614
 Prss23
protease, serine, 23
chr13_+_13529868 10.999 NM_010917
 Nid1
nidogen 1
chrX_-_48559008 10.779 NM_134163
 Mbnl3
muscleblind-like 3 (Drosophila)
chr8_-_105308910 10.747 NM_009866
 Cdh11
cadherin 11
chr9_-_85220730 10.482 NM_001160378
NM_001160379
 Fam46a

family with sequence similarity 46, member A

chr3_-_29912113 10.421 NM_007963
 Mecom
MDS1 and EVI1 complex locus
chr15_-_11835393 10.274 NM_001039181
NM_008728
 Npr3

natriuretic peptide receptor 3

chr16_-_85901362 9.958 NM_011782
 Adamts5
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
chr7_-_116760660 8.949 NM_001001326
NM_029811
 St5

suppression of tumorigenicity 5

chr7_+_119822831 8.428 NM_001166584
NM_009346
 Tead1

TEA domain family member 1

chr14_+_21748646 7.980 NM_009502
 Vcl
vinculin
chr4_-_147310804 7.618 NM_011122
 Plod1
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr1_+_12682510 7.610 NM_001198565
NM_001198566
 Sulf1

sulfatase 1


Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 65 entries
Enrichment   P-value GO Accession GO Term
29.75 7.10e-03 GO:0006509 membrane protein ectodomain proteolysis
20.82 3.29e-02 GO:0033619 membrane protein proteolysis
16.44 1.43e-03 GO:0045216 cell-cell junction organization
9.19 4.46e-02 GO:0045667 regulation of osteoblast differentiation
9.06 4.85e-02 GO:0034330 cell junction organization
6.13 1.60e-02 GO:0001655 urogenital system development
5.26 7.97e-03 GO:0048732 gland development
5.00 2.09e-03 GO:0001501 skeletal system development
4.90 1.08e-03 GO:0001701 in utero embryonic development
4.82 4.29e-02 GO:0030900 forebrain development
4.80 1.89e-02 GO:0048514 blood vessel morphogenesis
4.60 1.21e-02 GO:0007507 heart development
4.30 2.35e-02 GO:0001568 blood vessel development
4.24 1.21e-03 GO:0060429 epithelium development
4.09 1.80e-02 GO:0010551 regulation of gene-specific transcription from RNA polymerase II promoter
4.08 2.12e-04 GO:0009792 embryo development ending in birth or egg hatching
3.93 7.94e-04 GO:0043009 chordate embryonic development
3.80 1.27e-03 GO:0072358 cardiovascular system development
3.80 1.27e-03 GO:0072359 circulatory system development
3.24 3.76e-04 GO:0009790 embryo development

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
Enrichment   P-value GO Accession GO Term
4.55 1.18e-02 GO:0005911 cell-cell junction
2.20 3.73e-02 GO:0000267 cell fraction
1.47 3.51e-05 GO:0005737 cytoplasm
1.40 8.58e-07 GO:0044424 intracellular part
1.38 1.91e-06 GO:0005622 intracellular
1.35 1.77e-03 GO:0043226 organelle
1.35 2.87e-03 GO:0043229 intracellular organelle
1.35 1.01e-02 GO:0043231 intracellular membrane-bounded organelle
1.35 1.10e-02 GO:0043227 membrane-bounded organelle
1.16 1.41e-02 GO:0005623 cell
1.16 1.41e-02 GO:0044464 cell part

Gene overrepresentation in function category:

Showing 1 to 20 of 22 entries
Enrichment   P-value GO Accession GO Term
14.36 3.11e-02 GO:0005201 extracellular matrix structural constituent
4.76 2.36e-02 GO:0010843 promoter binding
4.47 3.82e-02 GO:0000975 regulatory region DNA binding
4.47 3.82e-02 GO:0001067 regulatory region nucleic acid binding
4.47 3.82e-02 GO:0044212 transcription regulatory region DNA binding
3.79 1.64e-02 GO:0016563 transcription activator activity
3.04 2.59e-02 GO:0019904 protein domain specific binding
3.01 2.21e-03 GO:0046983 protein dimerization activity
2.85 4.95e-03 GO:0001071 nucleic acid binding transcription factor activity
2.85 4.95e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
2.80 2.52e-02 GO:0043565 sequence-specific DNA binding
2.53 2.49e-02 GO:0019899 enzyme binding
2.49 2.09e-02 GO:0030528 transcription regulator activity
2.40 1.32e-03 GO:0008270 zinc ion binding
2.15 2.20e-03 GO:0003677 DNA binding
2.14 6.57e-03 GO:0046914 transition metal ion binding
1.78 2.59e-02 GO:0003676 nucleic acid binding
1.68 1.46e-02 GO:0046872 metal ion binding
1.66 1.99e-02 GO:0043169 cation binding
1.65 2.18e-02 GO:0043167 ion binding