Motif ID: AHR_ARNT_ARNT2.p2

Z-value: 2.134


Transcription factors associated with AHR_ARNT_ARNT2.p2:

Gene SymbolEntrez IDGene Name
Ahr 11622 aryl-hydrocarbon receptor
Arnt 11863 aryl hydrocarbon receptor nuclear translocator
Arnt2 11864 aryl hydrocarbon receptor nuclear translocator 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Arnt2chr7_-_915584680.661.7e-24Click!
Ahrchr12_-_36219651-0.222.7e-03Click!
Arntchr3_+_95238292-0.082.8e-01Click!


Activity profile for motif AHR_ARNT_ARNT2.p2.

activity profile for motif AHR_ARNT_ARNT2.p2


Sorted Z-values histogram for motif AHR_ARNT_ARNT2.p2

Sorted Z-values for motif AHR_ARNT_ARNT2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AHR_ARNT_ARNT2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_115890247 51.178 NM_001159569
NM_001159570
 Meis2

Meis homeobox 2

chr11_+_104092809 40.444 Mapt
microtubule-associated protein tau
chr18_+_64425037 32.934 St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr3_+_13471681 32.738 Ralyl
RALY RNA binding protein-like
chr8_+_86424565 26.320 Lphn1
latrophilin 1
chr8_+_73278577 25.819 NM_001166399
NM_009001
 Rab3a

RAB3A, member RAS oncogene family

chr3_-_57651621 25.587 NM_019410
 Pfn2
profilin 2
chr9_+_89804612 24.159 NM_001039655
NM_011245
 Rasgrf1

RAS protein-specific guanine nucleotide-releasing factor 1

chr4_-_151235861 24.086 NM_001081557
NM_001195565
 Camta1

calmodulin binding transcription activator 1

chr11_+_104092793 23.288 Mapt
microtubule-associated protein tau
chr5_-_122822329 23.041 1500011H22Rik
RIKEN cDNA 1500011H22 gene
chr6_+_110595586 22.978 NM_177328
 Grm7
glutamate receptor, metabotropic 7
chr18_-_25912453 22.802 NM_001146292
NM_001146293
NM_001146294
NM_001146295
NM_001174074
NM_133195
 Celf4





CUGBP, Elav-like family member 4





chr16_+_18777032 22.329 Cldn5
claudin 5
chr9_-_53822931 21.679 Elmod1
ELMO domain containing 1
chr11_+_101329457 21.536 Rnd2
Rho family GTPase 2
chr11_+_104092749 21.450 NM_001038609
NM_010838
 Mapt

microtubule-associated protein tau

chr7_-_17200285 21.059 NM_172739
 Grlf1
glucocorticoid receptor DNA binding factor 1
chr2_-_168567422 21.044 Atp9a
ATPase, class II, type 9A
chr15_-_77137015 20.345 Rbfox2
RNA binding protein, fox-1 homolog (C. elegans) 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 174 entries
Enrichment   P-value GO Accession GO Term
4.54 5.10e-03 GO:0090263 positive regulation of canonical Wnt receptor signaling pathway
3.79 1.17e-02 GO:0030177 positive regulation of Wnt receptor signaling pathway
3.61 5.87e-03 GO:0050808 synapse organization
2.82 1.03e-04 GO:0007005 mitochondrion organization
2.74 4.85e-02 GO:0060828 regulation of canonical Wnt receptor signaling pathway
2.65 6.40e-03 GO:0006184 GTP catabolic process
2.58 7.46e-03 GO:0030111 regulation of Wnt receptor signaling pathway
2.57 4.07e-02 GO:0021537 telencephalon development
2.55 1.45e-02 GO:0030324 lung development
2.51 1.98e-02 GO:0030323 respiratory tube development
2.49 3.25e-02 GO:0007411 axon guidance
2.48 1.97e-06 GO:0048812 neuron projection morphogenesis
2.46 3.44e-05 GO:0007409 axonogenesis
2.45 3.10e-02 GO:0046039 GTP metabolic process
2.44 9.75e-08 GO:0000904 cell morphogenesis involved in differentiation
2.40 2.91e-05 GO:0048667 cell morphogenesis involved in neuron differentiation
2.38 1.32e-07 GO:0031175 neuron projection development
2.37 2.49e-04 GO:0030900 forebrain development
2.35 1.60e-03 GO:0050804 regulation of synaptic transmission
2.33 1.04e-02 GO:0016055 Wnt receptor signaling pathway

Gene overrepresentation in compartment category:

Showing 1 to 20 of 52 entries
Enrichment   P-value GO Accession GO Term
3.75 1.86e-02 GO:0030175 filopodium
3.01 4.50e-03 GO:0044309 neuron spine
2.93 1.14e-02 GO:0043197 dendritic spine
2.70 1.81e-04 GO:0033267 axon part
2.51 5.90e-08 GO:0030424 axon
2.46 2.23e-04 GO:0005840 ribosome
2.27 3.63e-11 GO:0045202 synapse
2.21 9.36e-07 GO:0044456 synapse part
2.18 3.21e-02 GO:0005759 mitochondrial matrix
2.14 3.24e-02 GO:0045211 postsynaptic membrane
2.12 2.31e-02 GO:0031252 cell leading edge
2.06 1.71e-07 GO:0030529 ribonucleoprotein complex
2.03 1.49e-04 GO:0043025 neuronal cell body
2.01 1.72e-08 GO:0043005 neuron projection
1.93 7.21e-04 GO:0044297 cell body
1.91 1.02e-04 GO:0044463 cell projection part
1.84 2.82e-02 GO:0030425 dendrite
1.82 4.18e-02 GO:0015629 actin cytoskeleton
1.78 3.51e-02 GO:0005743 mitochondrial inner membrane
1.76 3.32e-02 GO:0019866 organelle inner membrane

Gene overrepresentation in function category:

Showing 1 to 20 of 36 entries
Enrichment   P-value GO Accession GO Term
11.88 3.73e-02 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity
9.90 1.75e-02 GO:0003706 ligand-regulated transcription factor activity
7.31 1.62e-03 GO:0030546 receptor activator activity
5.28 3.74e-02 GO:0031418 L-ascorbic acid binding
3.06 7.85e-05 GO:0019838 growth factor binding
2.58 4.85e-02 GO:0030165 PDZ domain binding
2.44 1.98e-03 GO:0003924 GTPase activity
2.15 3.81e-02 GO:0031406 carboxylic acid binding
2.13 1.76e-05 GO:0005525 GTP binding
2.03 9.91e-05 GO:0019001 guanyl nucleotide binding
2.03 9.91e-05 GO:0032561 guanyl ribonucleotide binding
2.03 4.71e-03 GO:0005083 small GTPase regulator activity
2.02 3.62e-02 GO:0005096 GTPase activator activity
1.96 1.85e-03 GO:0008047 enzyme activator activity
1.90 8.91e-06 GO:0019904 protein domain specific binding
1.90 3.49e-04 GO:0060589 nucleoside-triphosphatase regulator activity
1.86 1.17e-03 GO:0030695 GTPase regulator activity
1.79 8.00e-03 GO:0005198 structural molecule activity
1.75 4.13e-02 GO:0032403 protein complex binding
1.73 2.93e-05 GO:0003723 RNA binding