Motif ID: AIRE.p2

Z-value: 1.340


Transcription factors associated with AIRE.p2:

Gene SymbolEntrez IDGene Name
Aire 11634 autoimmune regulator (autoimmune polyendocrinopathy candidiasis ectodermal

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Airechr10_-_775062670.181.6e-02Click!


Activity profile for motif AIRE.p2.

activity profile for motif AIRE.p2


Sorted Z-values histogram for motif AIRE.p2

Sorted Z-values for motif AIRE.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of AIRE.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_70510714 22.942 NM_011727
 Xlr3c
X-linked lymphocyte-regulated 3C
chrX_+_70437517 19.008 NM_001081643
 Xlr3b
X-linked lymphocyte-regulated 3B
chrX_-_70342343 15.050 NM_001110784
 Xlr3a
X-linked lymphocyte-regulated 3A
chr11_+_83251195 14.578 NM_025492
 1700020L24Rik
RIKEN cDNA 1700020L24 gene
chr6_+_48689045 13.021 NM_008376
NM_175860
 Gimap1

GTPase, IMAP family member 1

chr6_+_48597232 12.478 NM_001077410
NM_212486
 Gimap8

GTPase, IMAP family member 8

chrX_-_7544940 12.133 NM_008089
 Gata1
GATA binding protein 1
chr4_+_15211137 11.233 Tmem64
transmembrane protein 64
chr11_+_83037063 10.579 AI662270
expressed sequence AI662270
chr14_+_51748742 10.492 NM_030098
 Rnase6
ribonuclease, RNase A family, 6
chr3_+_41419561 9.934 Phf17
PHD finger protein 17
chr10_-_61960613 9.752 Srgn
serglycin
chr13_+_24706474 9.369 NM_178658
 Fam65b
family with sequence similarity 65, member B
chr10_+_40290141 9.003 NM_027572
 Slc22a16
solute carrier family 22 (organic cation transporter), member 16
chr16_+_20128178 8.793 Klhl24
kelch-like 24 (Drosophila)
chr14_-_122314994 7.671 NM_182806
 Gpr18
G protein-coupled receptor 18
chr19_+_29441927 7.460 NM_021893
 Cd274
CD274 antigen
chr19_-_4190836 7.407 NM_178650
 Tbc1d10c
TBC1 domain family, member 10c
chr19_+_12873115 6.974 Lpxn
leupaxin
chr10_+_126504125 6.546



Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
3.37 3.12e-02 GO:0001669 acrosomal vesicle
1.22 1.11e-03 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
1.32 3.38e-03 GO:0003676 nucleic acid binding
1.12 3.87e-02 GO:0003674 molecular_function