Motif ID: ALX1.p2

Z-value: 1.087


Transcription factors associated with ALX1.p2:

Gene SymbolEntrez IDGene Name
Alx1 216285 ALX homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Alx1chr10_-_102491392-0.064.5e-01Click!


Activity profile for motif ALX1.p2.

activity profile for motif ALX1.p2


Sorted Z-values histogram for motif ALX1.p2

Sorted Z-values for motif ALX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ALX1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_-_88067758 13.711 NM_175418
Mybpc1
myosin binding protein C, slow-type
chr13_-_27656440 10.311 NM_023332
Prl8a9
prolactin family8, subfamily a, member 9
chr4_-_60594496 9.118 Mup1
major urinary protein 1
chr4_-_60594469 6.970 Mup1
major urinary protein 1
chr14_+_118666284 6.351 NM_001101609
Gm9376
predicted gene 9376
chrX_+_154137114 6.098 Smpx
small muscle protein, X-linked
chr4_+_48676385 6.072 NM_026509
Murc
muscle-related coiled-coil protein
chr16_+_36277233 5.987 NM_001082543
Stfa1
stefin A1
chr3_+_59533707 5.686 NM_001101531
Gm5538
predicted gene 5538
chr11_-_20729367 5.673 1110067D22Rik
RIKEN cDNA 1110067D22 gene
chrX_+_54032858 5.634 NM_001077362
Fhl1
four and a half LIM domains 1
chr6_+_83106397 5.505 NM_027948
1700003E16Rik
RIKEN cDNA 1700003E16 gene
chr11_+_67611772 5.228 NM_001013013
Dhrs7c
dehydrogenase/reductase (SDR family) member 7C
chr15_-_90764873 5.178 Kif21a
kinesin family member 21A
chr17_+_44090139 5.119 NM_030598
Rcan2
regulator of calcineurin 2
chrX_+_154137049 5.085 NM_025357
Smpx
small muscle protein, X-linked
chr10_+_56097078 4.945 NM_010288
Gja1
gap junction protein, alpha 1
chr5_-_116858596 4.848


chr7_-_23628623 4.795 NM_001166758
Vmn1r159
vomeronasal 1 receptor 159
chr7_-_21919146 4.778 NM_001166714
Vmn1r122
vomeronasal 1 receptor 122
chr7_+_21119185 4.773 NM_001166738
NM_001166752
Vmn1r104
Vmn1r152
vomeronasal 1 receptor 104
vomeronasal 1 receptor 152
chr7_+_22617369 4.648 NM_001166747
NM_001166755
Vmn1r135
Vmn1r163
vomeronasal 1 receptor 135
vomeronasal 1 receptor 163
chr13_+_25035416 4.639 Gpld1
glycosylphosphatidylinositol specific phospholipase D1
chr7_+_23840558 4.634 NM_001166747
NM_001166755
Vmn1r135
Vmn1r163
vomeronasal 1 receptor 135
vomeronasal 1 receptor 163
chr7_+_23307985 4.572 NM_001166738
NM_001166752
Vmn1r104
Vmn1r152
vomeronasal 1 receptor 104
vomeronasal 1 receptor 152
chr2_+_136539202 4.530 Snap25
synaptosomal-associated protein 25
chr15_+_91991704 4.378 NM_001159647
Cntn1
contactin 1
chr13_-_27702427 4.378 NM_029355
Prl7b1
prolactin family 7, subfamily b, member 1
chr1_-_152011986 4.334


chrX_+_54032914 4.271 Fhl1
four and a half LIM domains 1
chr12_+_25265583 4.081 NM_145890
Grhl1
grainyhead-like 1 (Drosophila)
chr3_-_10183884 4.024 NM_001030305
Pmp2
peripheral myelin protein 2
chr10_+_20760625 3.911 NM_001177776
Ahi1
Abelson helper integration site 1
chr6_+_83106466 3.719 1700003E16Rik
RIKEN cDNA 1700003E16 gene
chr14_-_56704033 3.671 NM_008572
Mcpt8
mast cell protease 8
chr8_-_49760037 3.460 NM_001145937
NM_011857
Odz3

odd Oz/ten-m homolog 3 (Drosophila)

chr7_+_23656242 3.450 NM_001166724
Vmn1r160
vomeronasal 1 receptor 160
chr8_+_55635683 3.447 NM_029569
Asb5
ankyrin repeat and SOCs box-containing 5
chr7_+_25421551 3.408 Lypd3
Ly6/Plaur domain containing 3
chr2_+_136539143 3.394 NM_011428
Snap25
synaptosomal-associated protein 25
chr7_+_21657274 3.323 NM_001166744
Vmn1r116
vomeronasal 1 receptor 116
chr7_+_24002350 3.319 NM_001166846
NM_001166848
NM_001166849
NM_001166850
NM_001166753
NM_001166759
Vmn1r110
Vmn1r130
Vmn1r137
Vmn1r165
Vmn1r178
Vmn1r155
Vmn1r107
vomeronasal 1 receptor 110
vomeronasal 1 receptor 130
vomeronasal 1 receptor 137
vomeronasal 1 receptor 165
vomeronasal 1 receptor 178
vomeronasal 1 receptor 155
vomeronasal 1 receptor 107
chr7_+_22779605 3.319 NM_001166846
NM_001166848
NM_001166849
NM_001166850
NM_001166753
NM_001166759
Vmn1r110
Vmn1r130
Vmn1r137
Vmn1r165
Vmn1r155
Vmn1r107
vomeronasal 1 receptor 110
vomeronasal 1 receptor 130
vomeronasal 1 receptor 137
vomeronasal 1 receptor 165
vomeronasal 1 receptor 155
vomeronasal 1 receptor 107
chr7_+_21254266 3.309 NM_001166846
NM_001166848
NM_001166849
NM_001166850
NM_001166753
NM_001166759
Vmn1r110
Vmn1r130
Vmn1r137
Vmn1r165
Vmn1r155
Vmn1r107
vomeronasal 1 receptor 110
vomeronasal 1 receptor 130
vomeronasal 1 receptor 137
vomeronasal 1 receptor 165
vomeronasal 1 receptor 155
vomeronasal 1 receptor 107
chr7_+_21453935 3.309 NM_001166846
NM_001166848
NM_001166849
NM_001166850
NM_001166753
NM_001166759
Vmn1r110
Vmn1r130
Vmn1r137
Vmn1r165
Vmn1r155
Vmn1r107
vomeronasal 1 receptor 110
vomeronasal 1 receptor 130
vomeronasal 1 receptor 137
vomeronasal 1 receptor 165
vomeronasal 1 receptor 155
vomeronasal 1 receptor 107
chr7_+_23443036 3.309 NM_001166846
NM_001166848
NM_001166849
NM_001166850
NM_001166753
NM_001166759
Vmn1r110
Vmn1r130
Vmn1r137
Vmn1r165
Vmn1r155
Vmn1r107
vomeronasal 1 receptor 110
vomeronasal 1 receptor 130
vomeronasal 1 receptor 137
vomeronasal 1 receptor 165
vomeronasal 1 receptor 155
vomeronasal 1 receptor 107
chr9_-_38455101 3.290 NM_146785
Olfr915
olfactory receptor 915
chr11_-_73137838 3.279 Aspa
aspartoacylase
chr7_+_22974395 3.273 NM_001167538
NM_001166750
Vmn1r95
Vmn1r143
vomeronasal 1 receptor, 95
vomeronasal 1 receptor 143
chr7_-_29415929 3.271 NM_175319
C330005M16Rik
RIKEN cDNA C330005M16 gene
chr11_-_31724523 3.265 D630024D03Rik
RIKEN cDNA D630024D03 gene
chr2_-_73150559 3.256 NM_025854
Cir1
corepressor interacting with RBPJ, 1
chr7_+_20779058 3.223 NM_001167538
NM_001166750
Vmn1r95
Vmn1r143
vomeronasal 1 receptor, 95
vomeronasal 1 receptor 143
chr18_+_36526187 3.188 0610010O12Rik
RIKEN cDNA 0610010O12 gene
chr19_+_34082779 3.177 NM_172837
Lipk
lipase, family member K
chr1_+_176102903 3.174 NM_011465
Spna1
spectrin alpha 1
chr19_-_44471675 3.139 Scd1
stearoyl-Coenzyme A desaturase 1
chr3_-_122737855 3.131 NM_021503
Myoz2
myozenin 2
chr7_+_21947203 3.083 NM_001166707
Vmn1r123
vomeronasal 1 receptor 123
chr7_+_22296798 3.081 NM_001166846
NM_001166848
NM_001166849
NM_001166850
NM_001166753
NM_001166759
Vmn1r110
Vmn1r130
Vmn1r137
Vmn1r165
Vmn1r155
Vmn1r107
vomeronasal 1 receptor 110
vomeronasal 1 receptor 130
vomeronasal 1 receptor 137
vomeronasal 1 receptor 165
vomeronasal 1 receptor 155
vomeronasal 1 receptor 107
chr10_-_80962881 3.026 NM_010102
S1pr4
sphingosine-1-phosphate receptor 4
chr19_-_44472087 3.024 Scd1
stearoyl-Coenzyme A desaturase 1
chr4_+_94405963 3.020 NM_013690
Tek
endothelial-specific receptor tyrosine kinase
chr3_-_92474213 2.939 NM_028625
Lce1a2
late cornified envelope 1A2
chr6_+_112223751 2.936 NM_144799
Lmcd1
LIM and cysteine-rich domains 1
chr17_-_90487479 2.936 Nrxn1
neurexin I
chr3_+_59885811 2.903 Sucnr1
succinate receptor 1
chr7_-_88837850 2.874 NM_001164087
Homer2
homer homolog 2 (Drosophila)
chr9_+_72584532 2.868 Nedd4
neural precursor cell expressed, developmentally down-regulated 4
chr13_+_113999866 2.844 NM_023612
Esm1
endothelial cell-specific molecule 1
chr7_+_25421586 2.831 NM_133743
Lypd3
Ly6/Plaur domain containing 3
chr7_-_23156057 2.806 NM_001166713
NM_001166751
Gm5728
Gm8660
predicted gene 5728
predicted gene 8660
chr13_-_23802635 2.801 NM_010424
Hfe
hemochromatosis
chr7_+_21357946 2.798 NM_001166845
NM_001166754
Vmn1r109
Vmn1r157
vomeronasal 1 receptor 109
vomeronasal 1 receptor 157
chr7_-_21838802 2.794 NM_001166715
Vmn1r120
vomeronasal 1 receptor 120
chr7_+_23198601 2.786 NM_001166844
Vmn1r100
vomeronasal 1 receptor 100
chr7_+_21003290 2.782 NM_001166844
Vmn1r100
vomeronasal 1 receptor 100
chrX_+_98644459 2.742 Itgb1bp2
integrin beta 1 binding protein 2
chrM_+_11741 2.725 ND5
NADH dehydrogenase subunit 5
chr18_+_69753035 2.708 Tcf4
transcription factor 4
chr3_+_116265890 2.691 NM_027321
NM_175413
Lrrc39

leucine rich repeat containing 39

chr7_+_20686506 2.684 NM_001166736
Vmn1r91
vomeronasal 1 receptor 91
chr13_-_13097596 2.642 NM_031191
Prl2c2
prolactin family 2, subfamily c, member 2
chr7_-_20960758 2.633 NM_001166713
NM_001166751
Gm5728
Gm8660
predicted gene 5728
predicted gene 8660
chr13_-_32873647 2.628 NM_001166030
Mylk4
myosin light chain kinase family, member 4
chr9_+_86636433 2.606 NM_178738
Prss35
protease, serine, 35
chr7_+_22057197 2.592 NM_001166740
Vmn1r125
vomeronasal 1 receptor 125
chr2_-_66512442 2.585 Scn7a
sodium channel, voltage-gated, type VII, alpha
chr7_+_22134391 2.554 NM_001166739
Vmn1r128
vomeronasal 1 receptor 128
chr14_+_13073221 2.525 Ptprg
protein tyrosine phosphatase, receptor type, G
chr9_+_39201377 2.498 NM_001011812
Olfr951
olfactory receptor 951
chr18_+_37663917 2.485 NM_053145
Pcdhb20
protocadherin beta 20
chr7_+_22399110 2.480 NM_001166748
Vmn1r139
vomeronasal 1 receptor 139
chr7_+_21556203 2.480 NM_001166847
Vmn1r112
vomeronasal 1 receptor 112
chr7_+_22881885 2.480 NM_001166748
Vmn1r139
vomeronasal 1 receptor 139
chr7_+_23546715 2.480 NM_001166845
NM_001166754
Vmn1r109
Vmn1r157
vomeronasal 1 receptor 109
vomeronasal 1 receptor 157
chr5_-_63157309 2.477 NM_178407
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_+_152891690 2.457 NM_145536
BC020535
cDNA sequence BC020535
chr17_+_80706746 2.444 NM_001145452
Arhgef33
Rho guanine nucleotide exchange factor (GEF) 33
chr7_+_24897332 2.443 NM_021307
Zfp112
zinc finger protein 112
chr17_-_34424623 2.384 NM_010378
H2-Aa
histocompatibility 2, class II antigen A, alpha
chr8_+_56040211 2.378 Gpm6a
glycoprotein m6a
chr8_-_46380114 2.354 Klkb1
kallikrein B, plasma 1
chr2_+_69735301 2.353 NM_001081548
NM_177783
Ubr3

ubiquitin protein ligase E3 component n-recognin 3

chr19_+_7631935 2.329 NM_139269
Pla2g16
phospholipase A2, group XVI
chr3_-_86803173 2.328 NM_007639
Cd1d1
CD1d1 antigen
chr5_-_124028994 2.320 Clip1
CAP-GLY domain containing linker protein 1
chr5_-_108298126 2.315 Evi5
ecotropic viral integration site 5
chr5_-_148706377 2.304 NM_027872
Slc46a3
solute carrier family 46, member 3
chr6_-_36761360 2.285 NM_008973
Ptn
pleiotrophin
chr9_+_121643763 2.275 Nktr
natural killer tumor recognition sequence
chr13_-_12892317 2.262 NM_011118
NM_011954
Prl2c3
Prl2c4
prolactin family 2, subfamily c, member 3
prolactin family 2, subfamily c, member 4
chr3_-_63941401 2.252 NM_001104592
Vmn2r2
vomeronasal 2, receptor 2
chr13_-_13097649 2.252 Prl2c2
prolactin family 2, subfamily c, member 2
chr7_+_51097638 2.235 NM_026806
Klk5
kallikrein related-peptidase 5
chr5_+_88095232 2.183 NM_007784
Csn1s1
casein alpha s1
chr7_-_30638635 2.165 NM_173738
Zfp940
zinc finger protein 940
chr16_+_17489703 2.138 Aifm3
apoptosis-inducing factor, mitochondrion-associated 3
chr13_-_27530465 2.103 NM_011167
Prl8a6
prolactin family 8, subfamily a, member 6
chr15_-_8273428 2.088 Nipbl
Nipped-B homolog (Drosophila)
chr8_-_46380165 2.084 NM_008455
Klkb1
kallikrein B, plasma 1
chr17_+_47873941 2.065 NM_001161722
Tcfeb
transcription factor EB
chr5_-_73033990 2.065 NM_007723
Cnga1
cyclic nucleotide gated channel alpha 1
chr13_-_27808594 2.018 NM_011120
Prl7d1
prolactin family 7, subfamily d, member 1
chr3_-_124128908 2.006 NM_027939
1700006A11Rik
RIKEN cDNA 1700006A11 gene
chr18_+_44166024 2.005 Spink5
serine peptidase inhibitor, Kazal type 5
chr17_+_40948047 1.992 NM_011269
Rhag
Rhesus blood group-associated A glycoprotein
chr8_+_56040193 1.990 Gpm6a
glycoprotein m6a
chr5_+_149114763 1.988 Mtus2
microtubule associated tumor suppressor candidate 2
chr3_+_59885782 1.983 NM_032400
Sucnr1
succinate receptor 1
chr9_-_99287199 1.972 Mras
muscle and microspikes RAS
chr10_-_85474581 1.957 NM_177772
Bpil2
bactericidal/permeability-increasing protein-like 2
chr5_+_90890764 1.944 Alb
albumin
chr16_-_3872273 1.943 NM_001033159
Zfp597
zinc finger protein 597
chr4_+_88495990 1.925 NM_010502
Ifna1
interferon alpha 1
chr6_-_137119016 1.924 NM_181988
Rerg
RAS-like, estrogen-regulated, growth-inhibitor
chr9_-_82826139 1.922 Phip
pleckstrin homology domain interacting protein
chr1_-_39708086 1.914 Creg2
cellular repressor of E1A-stimulated genes 2
chr9_-_39066263 1.912 NM_146506
Olfr945
olfactory receptor 945
chr13_-_27605067 1.908 NM_023741
Prl8a8
prolactin family 8, subfamily a, member 81
chr18_+_59222034 1.907 NM_001167925
NM_173759
A730017C20Rik

RIKEN cDNA A730017C20 gene

chr7_-_116867284 1.894 NM_001040700
BC051019
cDNA sequence BC051019
chrY_-_133778 1.883 NM_009570
Zfy1
zinc finger protein 1, Y linked
chr9_+_96159123 1.879 NM_001184709
Tfdp2
transcription factor Dp 2
chr7_-_106976715 1.841 NM_016720
Neu3
neuraminidase 3
chr5_+_88354611 1.827 NM_007786
Csn3
casein kappa
chrX_+_145540098 1.794 NM_001099920
Gm15093
predicted gene 15093
chrX_+_145889719 1.794 NM_001099920
Gm15093
predicted gene 15093
chrX_+_144756676 1.794 NM_001099920
Gm15093
predicted gene 15093
chrX_+_144923491 1.794 NM_001082966
Gm15114
predicted gene 15114
chrX_+_145706919 1.794 NM_001099920
Gm15093
predicted gene 15093
chr7_-_86531587 1.785 Rlbp1
retinaldehyde binding protein 1
chrX_+_144435111 1.782 NM_001099920
Gm15093
predicted gene 15093
chrY_-_623013 1.732 NM_012008
Ddx3y
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr5_-_88128419 1.732 NM_009972
Csn2
casein beta
chr18_+_80315134 1.672 Pard6g
par-6 partitioning defective 6 homolog gamma (C. elegans)
chr13_-_27759883 1.665 NM_011168
Prl7a2
prolactin family 7, subfamily a, member 2
chr6_+_41304103 1.658 NM_001038996
Try10
trypsin 10
chr13_-_62659870 1.655 Zfp935
Zfp934
zinc finger protein 935
zinc finger protein 934
chr3_-_88576415 1.648 NM_018804
Syt11
synaptotagmin XI
chrX_+_162782484 1.634 NM_001177955
NM_001177956
NM_001177957
NM_001177958
NM_001177959
NM_001177960
Gpm6b





glycoprotein m6b





chr8_-_113917651 1.588 NM_178086
Fa2h
fatty acid 2-hydroxylase
chr7_-_22949053 1.583 NM_001166723
NM_001166749
Vmn1r94
Vmn1r142
vomeronasal 1 receptor 94
vomeronasal 1 receptor 142
chr7_+_30601080 1.582 NM_001145880
NM_146185
Zfp790

zinc finger protein 790

chr13_-_23802696 1.571 Hfe
hemochromatosis
chr2_-_29979973 1.568 NM_178694
Zer1
zer-1 homolog (C. elegans)
chr4_-_63283448 1.555 NM_029324
1700018C11Rik
RIKEN cDNA 1700018C11 gene
chr11_-_6333725 1.545 H2afv
H2A histone family, member V
chr6_+_24478143 1.538 NM_080847
Asb15
ankyrin repeat and SOCS box-containing 15
chr12_-_86447380 1.529 NM_175198
Prox2
prospero homeobox 2
chr3_+_26536552 1.524 NM_027583
NM_029150
Spata16

spermatogenesis associated 16

chr18_-_12914177 1.506 Osbpl1a
oxysterol binding protein-like 1A
chr2_+_71892681 1.505 Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr14_+_14286471 1.500 NM_001163032
Synpr
synaptoporin
chr16_-_95078278 1.494 NM_001025590
Kcnj6
potassium inwardly-rectifying channel, subfamily J, member 6
chr3_-_8666930 1.490 Hey1
hairy/enhancer-of-split related with YRPW motif 1
chr7_+_53339469 1.484


chr5_+_67698177 1.480 NM_178651
Slc30a9
solute carrier family 30 (zinc transporter), member 9
chr7_-_20753725 1.479 NM_001166723
NM_001166749
Vmn1r94
Vmn1r142
vomeronasal 1 receptor 94
vomeronasal 1 receptor 142
chr10_+_127335573 1.479 NM_027301
Sdr9c7
4short chain dehydrogenase/reductase family 9C, member 7
chr13_+_42961598 1.467 Phactr1
phosphatase and actin regulator 1
chr7_-_22104879 1.465 NM_001166726
Vmn1r127
vomeronasal 1 receptor 127
chr18_-_60432920 1.449 NM_001034859
Gm4841
predicted gene 4841
chr16_-_26371711 1.448 NM_016674
Cldn1
claudin 1
chr8_-_55804030 1.441 NM_028220
Wdr17
WD repeat domain 17
chr1_-_175266945 1.430 Cadm3
cell adhesion molecule 3
chr10_+_19341803 1.430 NM_178258
Il22ra2
interleukin 22 receptor, alpha 2
chr7_-_23284696 1.411 NM_001166712
Vmn1r151
vomeronasal 1 receptor 151
chr7_-_21095882 1.405 NM_001166737
Vmn1r103
vomeronasal 1 receptor 103
chr7_+_4416336 1.403 NM_026146
Eps8l1
EPS8-like 1
chr7_+_31561419 1.401 NM_028618
Dmkn
dermokine
chr1_-_109057687 1.399 NM_198680
Serpinb3b
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B
chr2_-_29980091 1.386 Zer1
zer-1 homolog (C. elegans)
chr2_-_110145819 1.382 Bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr2_-_155949753 1.375 Nfs1
nitrogen fixation gene 1 (S. cerevisiae)
chr14_-_17407701 1.373 NM_011243
Rarb
retinoic acid receptor, beta
chr6_-_90666474 1.367 NM_001134383
Iqsec1
IQ motif and Sec7 domain 1
chr9_-_79825502 1.361 NM_001081243
Filip1
filamin A interacting protein 1
chr7_-_21630003 1.355 NM_001166745
Vmn1r115
vomeronasal 1 receptor 115
chr1_+_177562321 1.344 NM_133809
Kmo
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.27 2.00e-04 GO:0005575 cellular_component
1.52 3.54e-02 GO:0005576 extracellular region

Nothing significant found in function category.