Motif ID: ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Z-value: 2.085


Transcription factors associated with ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2:

Gene SymbolEntrez IDGene Name
Arnt 11863 aryl hydrocarbon receptor nuclear translocator
Arnt2 11864 aryl hydrocarbon receptor nuclear translocator 2
Bhlhe40 20893 basic helix-loop-helix family, member e40
Max 17187 Max protein
Myc 17869 myelocytomatosis oncogene
Usf1 22278 upstream transcription factor 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mycchr15_+_618171020.572.2e-17Click!
Bhlhe40chr6_+_108610606-0.401.6e-08Click!
Maxchr12_-_780630110.138.2e-02Click!
Usf1chr1_+_1733418110.092.1e-01Click!
Arnt2chr7_-_91558468-0.064.2e-01Click!
Arntchr3_+_95238292-0.064.6e-01Click!


Activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2.

activity profile for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2


Sorted Z-values histogram for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

Sorted Z-values for motif ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ARNT_ARNT2_BHLHB2_MAX_MYC_USF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr10_+_126500607 88.202 NM_009870
Cdk4
cyclin-dependent kinase 4
chr14_+_51544629 53.467 NM_009687
Apex1
apurinic/apyrimidinic endonuclease 1
chr9_+_21172314 41.889 NM_001042707
NM_001042708
NM_001042709
NM_010561
Ilf3



interleukin enhancer binding factor 3



chr19_-_4201541 41.200 NM_011237
Rad9
RAD9 homolog (S. pombe)
chr9_+_21216277 35.101 NM_021888
Qtrt1
queuine tRNA-ribosyltransferase 1
chr6_-_88848650 30.975 NM_008564
Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr17_-_35137799 30.418 D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
chr1_+_59741800 30.387 NM_018868
Nop58
NOP58 ribonucleoprotein homolog (yeast)
chr11_+_69814046 30.196 NM_007888
Dvl2
dishevelled 2, dsh homolog (Drosophila)
chr4_+_147965596 26.175 NM_009272
Srm
spermidine synthase
chr5_-_138613028 26.148 NM_008568
Mcm7
minichromosome maintenance deficient 7 (S. cerevisiae)
chr4_+_134024234 25.763 NM_019641
Stmn1
stathmin 1
chr5_-_77380593 24.904 NM_172146
Ppat
phosphoribosyl pyrophosphate amidotransferase
chr7_-_52722144 24.873 NM_007527
Bax
BCL2-associated X protein
chr17_+_35137995 23.831 Vars
valyl-tRNA synthetase
chr17_-_35137690 22.958 D17H6S56E-5
DNA segment, Chr 17, human D6S56E 5
chr15_+_59205752 22.681 NM_001164604
NM_026746
Nsmce2

non-SMC element 2 homolog (MMS21, S. cerevisiae)

chr3_+_89577436 22.201 NM_027315
Ube2q1
ubiquitin-conjugating enzyme E2Q (putative) 1
chrX_-_131076136 21.868 NM_013898
Timm8a1
translocase of inner mitochondrial membrane 8 homolog a1 (yeast)
chr17_-_53828596 21.756 NM_028232
Sgol1
shugoshin-like 1 (S. pombe)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 110 entries
Enrichment   P-value GO Accession GO Term
8.09 6.58e-04 GO:0006400 tRNA modification
6.30 2.01e-05 GO:0006405 RNA export from nucleus
5.76 7.72e-03 GO:0006406 mRNA export from nucleus
4.80 6.95e-05 GO:0051168 nuclear export
4.50 1.94e-07 GO:0006403 RNA localization
4.49 4.91e-07 GO:0050657 nucleic acid transport
4.49 4.91e-07 GO:0050658 RNA transport
4.49 4.91e-07 GO:0051236 establishment of RNA localization
4.38 1.07e-05 GO:0051028 mRNA transport
4.38 4.07e-03 GO:0009451 RNA modification
4.27 1.31e-07 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
3.72 6.44e-05 GO:0006414 translational elongation
3.60 3.51e-03 GO:0008033 tRNA processing
3.60 3.51e-03 GO:0018394 peptidyl-lysine acetylation
3.55 8.49e-03 GO:0016573 histone acetylation
3.51 2.76e-03 GO:0006473 protein acetylation
3.45 1.29e-02 GO:0006475 internal protein amino acid acetylation
3.45 1.29e-02 GO:0018393 internal peptidyl-lysine acetylation
3.40 6.98e-04 GO:0006364 rRNA processing
3.39 8.93e-07 GO:0006913 nucleocytoplasmic transport

Gene overrepresentation in compartment category:

Showing 1 to 20 of 40 entries
Enrichment   P-value GO Accession GO Term
6.06 7.70e-03 GO:0031519 PcG protein complex
3.82 7.88e-03 GO:0016363 nuclear matrix
3.66 3.27e-03 GO:0034708 methyltransferase complex
3.66 3.27e-03 GO:0035097 histone methyltransferase complex
3.15 3.90e-02 GO:0000123 histone acetyltransferase complex
3.11 7.80e-06 GO:0016604 nuclear body
2.87 6.04e-14 GO:0005730 nucleolus
2.67 4.24e-02 GO:0000790 nuclear chromatin
2.49 8.73e-12 GO:0030529 ribonucleoprotein complex
2.47 2.02e-03 GO:0005840 ribosome
2.40 1.81e-03 GO:0005635 nuclear envelope
2.32 1.08e-13 GO:0044451 nucleoplasm part
2.27 2.30e-29 GO:0031981 nuclear lumen
2.26 1.52e-19 GO:0005654 nucleoplasm
2.23 6.37e-03 GO:0000228 nuclear chromosome
2.23 2.07e-02 GO:0044454 nuclear chromosome part
2.22 2.61e-34 GO:0044428 nuclear part
2.22 4.28e-32 GO:0070013 intracellular organelle lumen
2.22 5.84e-32 GO:0043233 organelle lumen
2.19 2.28e-31 GO:0031974 membrane-enclosed lumen

Gene overrepresentation in function category:

Showing 1 to 20 of 30 entries
Enrichment   P-value GO Accession GO Term
4.63 4.53e-02 GO:0003746 translation elongation factor activity
3.71 8.13e-06 GO:0008135 translation factor activity, nucleic acid binding
2.60 1.57e-20 GO:0003723 RNA binding
2.60 1.91e-02 GO:0016853 isomerase activity
2.58 3.07e-02 GO:0003735 structural constituent of ribosome
2.17 2.93e-02 GO:0043566 structure-specific DNA binding
2.10 1.14e-03 GO:0008134 transcription factor binding
2.07 2.47e-02 GO:0003712 transcription cofactor activity
2.06 2.69e-02 GO:0000989 transcription factor binding transcription factor activity
2.04 3.49e-02 GO:0000988 protein binding transcription factor activity
1.83 9.60e-26 GO:0003676 nucleic acid binding
1.67 9.35e-11 GO:0003677 DNA binding
1.67 1.08e-04 GO:0030528 transcription regulator activity
1.64 1.44e-02 GO:0043565 sequence-specific DNA binding
1.63 3.95e-03 GO:0001071 nucleic acid binding transcription factor activity
1.63 3.95e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.59 3.97e-03 GO:0019899 enzyme binding
1.46 3.78e-03 GO:0008270 zinc ion binding
1.45 7.12e-06 GO:0000166 nucleotide binding
1.42 2.82e-03 GO:0046914 transition metal ion binding