Motif ID: BACH2.p2

Z-value: 1.479


Transcription factors associated with BACH2.p2:

Gene SymbolEntrez IDGene Name
Bach2 12014 BTB and CNC homology 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Bach2chr4_+_32504409-0.213.7e-03Click!


Activity profile for motif BACH2.p2.

activity profile for motif BACH2.p2


Sorted Z-values histogram for motif BACH2.p2

Sorted Z-values for motif BACH2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of BACH2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_86589782 35.675 NM_008615
 Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr4_-_129851289 34.948 Tinagl1
tubulointerstitial nephritis antigen-like 1
chr7_+_135667095 24.645 NM_013863
 Bag3
BCL2-associated athanogene 3
chr7_+_135667279 24.187 Bag3
BCL2-associated athanogene 3
chr1_+_173367685 23.773 NM_172647
 F11r
F11 receptor
chr11_-_55223449 23.589 Sparc
secreted acidic cysteine rich glycoprotein
chr7_+_31337558 23.315 Hspb6
heat shock protein, alpha-crystallin-related, B6
chr12_+_31950252 22.272 Lamb1
laminin B1
chr7_-_112630662 22.049 NM_028444
 Prkcdbp
protein kinase C, delta binding protein
chr12_+_31950097 21.794 NM_008482
 Lamb1
laminin B1
chr9_+_44850426 21.298 NM_007962
 Mpzl2
myelin protein zero-like 2
chr7_+_31338319 20.589 NM_001012401
 Hspb6
heat shock protein, alpha-crystallin-related, B6
chr7_-_116688776 20.553 St5
suppression of tumorigenicity 5
chr7_-_30033397 20.011 2200002D01Rik
RIKEN cDNA 2200002D01 gene
chr19_-_38199291 20.011 NM_011255
 Rbp4
retinol binding protein 4, plasma
chr7_+_138087002 19.927 Htra1
HtrA serine peptidase 1
chr19_-_38199036 18.754 Rbp4
retinol binding protein 4, plasma
chr18_+_61204798 18.456 NM_001146268
NM_008809
 Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr3_-_88297220 18.331 NM_019390
 Lmna
lamin A
chr11_+_78001871 18.058 NM_001159482
 Rab34
RAB34, member of RAS oncogene family

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 35 entries
Enrichment   P-value GO Accession GO Term
6.44 4.60e-02 GO:0034329 cell junction assembly
5.19 1.33e-02 GO:0007519 skeletal muscle tissue development
5.00 1.88e-02 GO:0060538 skeletal muscle organ development
4.83 1.89e-03 GO:0031398 positive regulation of protein ubiquitination
3.92 1.13e-02 GO:0031396 regulation of protein ubiquitination
3.84 1.44e-02 GO:0014706 striated muscle tissue development
3.79 8.51e-03 GO:0060537 muscle tissue development
2.60 1.03e-02 GO:0043086 negative regulation of catalytic activity
2.46 4.13e-02 GO:0016044 cellular membrane organization
2.45 4.49e-02 GO:0061024 membrane organization
2.43 1.10e-03 GO:0007155 cell adhesion
2.41 1.34e-03 GO:0022610 biological adhesion
2.31 3.40e-02 GO:0044092 negative regulation of molecular function
2.22 3.33e-04 GO:0009888 tissue development
2.22 1.57e-02 GO:0042180 cellular ketone metabolic process
2.17 3.57e-02 GO:0006082 organic acid metabolic process
1.99 4.92e-03 GO:0044248 cellular catabolic process
1.94 1.38e-03 GO:0009056 catabolic process
1.92 1.27e-02 GO:0010033 response to organic substance
1.89 2.47e-05 GO:0065008 regulation of biological quality

Gene overrepresentation in compartment category:

Showing 1 to 20 of 33 entries
Enrichment   P-value GO Accession GO Term
6.55 6.80e-04 GO:0000502 proteasome complex
6.15 3.42e-02 GO:0032432 actin filament bundle
5.88 4.57e-02 GO:0005913 cell-cell adherens junction
4.77 2.97e-02 GO:0001726 ruffle
4.66 1.51e-02 GO:0042383 sarcolemma
3.78 7.98e-04 GO:0031252 cell leading edge
3.67 8.82e-05 GO:0016323 basolateral plasma membrane
3.63 1.23e-06 GO:0048471 perinuclear region of cytoplasm
3.60 3.65e-02 GO:0005912 adherens junction
3.50 2.27e-03 GO:0016324 apical plasma membrane
2.94 8.13e-03 GO:0045177 apical part of cell
2.27 2.67e-04 GO:0005615 extracellular space
2.26 2.12e-02 GO:0009986 cell surface
2.17 3.51e-05 GO:0044421 extracellular region part
2.03 3.65e-02 GO:0030054 cell junction
1.87 1.70e-03 GO:0000267 cell fraction
1.81 7.19e-04 GO:0005856 cytoskeleton
1.80 4.38e-05 GO:0005576 extracellular region
1.80 1.40e-02 GO:0042995 cell projection
1.79 8.23e-04 GO:0005739 mitochondrion

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
Enrichment   P-value GO Accession GO Term
12.08 1.50e-02 GO:0003995 acyl-CoA dehydrogenase activity
6.96 1.80e-03 GO:0051287 NAD binding
3.44 7.16e-03 GO:0050662 coenzyme binding
3.18 1.25e-03 GO:0048037 cofactor binding
2.79 2.25e-02 GO:0004857 enzyme inhibitor activity
2.58 4.39e-02 GO:0019900 kinase binding
2.53 5.91e-03 GO:0008289 lipid binding
2.36 3.64e-03 GO:0008092 cytoskeletal protein binding
2.14 3.86e-03 GO:0016491 oxidoreductase activity
2.07 1.02e-02 GO:0046983 protein dimerization activity
1.97 8.79e-03 GO:0019899 enzyme binding
1.51 1.67e-09 GO:0005515 protein binding
1.36 1.34e-03 GO:0003824 catalytic activity
1.27 7.28e-08 GO:0005488 binding