Motif ID: CACAGUG

Z-value: 0.657


Mature miRNA associated with seed CACAGUG:

NamemiRBase Accession
mmu-miR-128 MIMAT0000140



Activity profile for motif CACAGUG.

activity profile for motif CACAGUG


Sorted Z-values histogram for motif CACAGUG

Sorted Z-values for motif CACAGUG



Network of associatons between targets according to the STRING database.



First level regulatory network of CACAGUG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_110357230 8.978 NM_007792
Csrp2
cysteine and glycine-rich protein 2
chr8_-_25549415 7.061 NM_026931
1810011O10Rik
RIKEN cDNA 1810011O10 gene
chr9_-_58884114 6.266 NM_001042752
NM_008684
Neo1

neogenin

chr9_+_32031833 5.539 NM_177379
Arhgap32
Rho GTPase activating protein 32
chr4_+_109088251 5.466 NM_001145948
Ttc39a
tetratricopeptide repeat domain 39A
chr13_-_34437042 5.381 NM_001033167
Slc22a23
solute carrier family 22, member 23
chr2_+_136539143 5.219 NM_011428
Snap25
synaptosomal-associated protein 25
chrX_+_70728939 5.107 NM_007542
Bgn
biglycan
chr19_-_34329804 5.093 NM_007392
Acta2
actin, alpha 2, smooth muscle, aorta
chr4_+_109079704 5.014 NM_153392
Ttc39a
tetratricopeptide repeat domain 39A
chr6_+_17413930 4.782 NM_008591
Met
met proto-oncogene
chr9_+_31923720 4.702 NM_001195632
Arhgap32
Rho GTPase activating protein 32
chr2_-_115890747 4.685 NM_001136072
NM_001159567
NM_001159568
NM_010825
Meis2



Meis homeobox 2



chr2_-_115890247 4.592 NM_001159569
NM_001159570
Meis2

Meis homeobox 2

chr12_+_80130149 4.532 NM_181073
Plekhh1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 1
chr16_-_35490849 4.412 NM_028295
Pdia5
protein disulfide isomerase associated 5
chr2_-_103143352 4.230 NM_007914
Ehf
ets homologous factor
chr10_-_8605668 4.160 NM_175155
Sash1
SAM and SH3 domain containing 1
chr18_-_33623668 4.122 NM_001109988
D0H4S114
DNA segment, human D4S114
chr15_+_54402914 4.120 NM_178920
Mal2
mal, T-cell differentiation protein 2
chr9_-_49607164 4.082 NM_001081445
NM_001113204
NM_010875
Ncam1


neural cell adhesion molecule 1


chr5_-_108304062 4.012 NM_007964
Evi5
ecotropic viral integration site 5
chr1_-_82287990 3.989 NM_010570
Irs1
insulin receptor substrate 1
chr4_-_55545337 3.985 NM_010637
Klf4
Kruppel-like factor 4 (gut)
chr5_+_75548309 3.950 NM_011058
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr18_-_33623069 3.851 NM_001109990
D0H4S114
DNA segment, human D4S114
chr18_-_33623287 3.826 NM_053078
D0H4S114
DNA segment, human D4S114
chr17_+_43804373 3.812 NM_018887
Cyp39a1
cytochrome P450, family 39, subfamily a, polypeptide 1
chr3_+_129235284 3.765 NM_130450
Elovl6
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr18_-_33623400 3.746 NM_001109989
D0H4S114
DNA segment, human D4S114
chr10_-_36858671 3.507 NM_008538
Marcks
myristoylated alanine rich protein kinase C substrate
chr2_+_167906462 3.444 NM_021409
Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr5_+_75552144 3.382 NM_001083316
Pdgfra
platelet derived growth factor receptor, alpha polypeptide
chr2_-_130468507 3.374 NM_197945
Prosapip1
ProSAPiP1 protein
chr3_-_102007885 3.211 NM_001165951
Vangl1
vang-like 1 (van gogh, Drosophila)
chr10_+_94977721 3.167 NM_080560
Ube2n
ubiquitin-conjugating enzyme E2N
chr8_-_48437701 3.125 NM_175162
Stox2
storkhead box 2
chr18_-_34166859 3.122 NM_013512
Epb4.1l4a
erythrocyte protein band 4.1-like 4a
chr15_+_7090525 3.121 NM_013584
Lifr
leukemia inhibitory factor receptor
chrX_+_138662479 3.094 NM_001161430
Nxt2
nuclear transport factor 2-like export factor 2
chr5_-_21850490 3.022 NM_011261
Reln
reelin
chr3_-_157587998 2.978 NM_145953
Cth
cystathionase (cystathionine gamma-lyase)
chr5_+_102194126 2.948 NM_173370
Cds1
CDP-diacylglycerol synthase 1
chr15_-_90880241 2.889 NM_001109040
NM_001109041
NM_001109042
NM_016705
Kif21a



kinesin family member 21A



chr3_+_145421621 2.878 NM_026993
Ddah1
dimethylarginine dimethylaminohydrolase 1
chr6_-_118147735 2.875 NM_001080780
NM_009050
Ret

ret proto-oncogene

chr9_+_83441886 2.865 NM_172507
Sh3bgrl2
SH3 domain binding glutamic acid-rich protein like 2
chr3_-_102008512 2.837 NM_177545
Vangl1
vang-like 1 (van gogh, Drosophila)
chr8_-_48374755 2.835 NM_001114311
Stox2
storkhead box 2
chr8_+_24521967 2.820 NM_013834
Sfrp1
secreted frizzled-related protein 1
chr13_-_117099629 2.784 NM_021459
Isl1
ISL1 transcription factor, LIM/homeodomain
chr8_+_12949417 2.778 NM_001159485
NM_001159486
Mcf2l

mcf.2 transforming sequence-like

chrX_+_138662725 2.765 NM_172782
Nxt2
nuclear transport factor 2-like export factor 2
chr4_+_62876389 2.729 NM_025685
Col27a1
collagen, type XXVII, alpha 1
chr15_-_98438063 2.700 NM_007405
Adcy6
adenylate cyclase 6
chr14_+_48740495 2.697 NM_033602
Peli2
pellino 2
chr15_+_85566122 2.650 NM_011144
Ppara
peroxisome proliferator activated receptor alpha
chr5_-_107718503 2.619 NM_011578
Tgfbr3
transforming growth factor, beta receptor III
chr10_+_51953390 2.531 NM_025705
Dcbld1
discoidin, CUB and LCCL domain containing 1
chr8_+_12915892 2.527 NM_178076
Mcf2l
mcf.2 transforming sequence-like
chr1_-_138850206 2.516 NM_001159769
Nr5a2
nuclear receptor subfamily 5, group A, member 2
chr13_+_111185251 2.494 NM_152804
Plk2
polo-like kinase 2 (Drosophila)
chr9_+_72510153 2.471 NM_010890
Nedd4
neural precursor cell expressed, developmentally down-regulated 4
chr9_-_30939380 2.451 NM_011176
St14
suppression of tumorigenicity 14 (colon carcinoma)
chr10_-_83996632 2.416 NM_175451
Ckap4
cytoskeleton-associated protein 4
chr10_+_12810593 2.406 NM_009538
Plagl1
pleiomorphic adenoma gene-like 1
chr8_-_105308910 2.403 NM_009866
Cdh11
cadherin 11
chr15_+_85565935 2.400 NM_001113418
Ppara
peroxisome proliferator activated receptor alpha
chr10_+_115738429 2.398 NM_029928
Ptprb
protein tyrosine phosphatase, receptor type, B
chr15_+_99223377 2.376 NM_001171034
NM_001171036
NM_026669
Tmbim6


transmembrane BAX inhibitor motif containing 6


chr1_+_88199795 2.361 NM_145222
B3gnt7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 7
chr4_+_97444312 2.348 NM_001122953
NM_010905
Nfia

nuclear factor I/A

chr14_-_65881225 2.337 NM_021458
Fzd3
frizzled homolog 3 (Drosophila)
chr12_+_110691637 2.330 NM_001190703
NM_001190704
NM_001190705
NM_010052
Dlk1



delta-like 1 homolog (Drosophila)



chr5_-_74464390 2.328 NM_177561
Usp46
ubiquitin specific peptidase 46
chr4_-_154010868 2.283 NM_001177995
NM_027504
Prdm16

PR domain containing 16

chr4_+_101092307 2.247 NM_009647
Ak4
adenylate kinase 4
chr18_+_69505374 2.242 NM_001083967
Tcf4
transcription factor 4
chr11_-_86807216 2.230 NM_001005341
Ypel2
yippee-like 2 (Drosophila)
chr12_+_109648864 2.171 NM_001043336
Eml1
echinoderm microtubule associated protein like 1
chr12_+_109660951 2.130 NM_001043335
Eml1
echinoderm microtubule associated protein like 1
chr4_+_101091913 2.125 NM_001177605
NM_001177604
Ak4

adenylate kinase 4

chr5_-_115140869 2.124 NM_019821
Gltp
glycolipid transfer protein
chr1_+_66515003 2.113 NM_175510
Unc80
unc-80 homolog (C. elegans)
chr11_-_113427050 2.104 NM_001166503
NM_027216
Slc39a11

solute carrier family 39 (metal ion transporter), member 11

chr6_-_53770687 2.093 NM_025817
Tril
TLR4 interactor with leucine-rich repeats
chr7_-_77505248 2.033 NM_009697
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr1_+_153602492 2.013 NM_001039644
Edem3
ER degradation enhancer, mannosidase alpha-like 3
chr18_+_69504145 2.002 NM_013685
Tcf4
transcription factor 4
chr15_+_99223622 1.996 NM_001171035
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr10_-_82996846 1.978 NM_153543
Aldh1l2
aldehyde dehydrogenase 1 family, member L2
chr1_-_138856866 1.972 NM_030676
Nr5a2
nuclear receptor subfamily 5, group A, member 2
chr2_+_181531011 1.966 NM_001171680
Myt1
myelin transcription factor 1
chr13_+_75844906 1.955 NM_138953
Ell2
elongation factor RNA polymerase II 2
chr5_+_73872293 1.898 NM_001190734
Dcun1d4
DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)
chr3_+_5218545 1.881 NM_030708
Zfhx4
zinc finger homeodomain 4
chr4_-_82151180 1.880 NM_001113209
NM_001113210
NM_008687
Nfib


nuclear factor I/B


chr4_+_54960816 1.877 NM_172867
Zfp462
zinc finger protein 462
chr8_+_81552335 1.875 NM_178267
Zfp827
zinc finger protein 827
chr6_+_91162756 1.873 NM_001081437
NM_007992
Fbln2

fibulin 2

chr18_-_39078304 1.857 NM_010197
Fgf1
fibroblast growth factor 1
chr2_+_91490266 1.850 NM_001145902
Arhgap1
Rho GTPase activating protein 1
chr13_-_114408704 1.833 NM_130796
Snx18
sorting nexin 18
chr2_+_48669628 1.830 NM_007396
Acvr2a
activin receptor IIA
chr4_+_97248556 1.823 NM_001122952
Nfia
D130039L10Rik
nuclear factor I/A
RIKEN cDNA D130039L10 gene
chr1_-_186556329 1.781 NM_008250
Hlx
H2.0-like homeobox
chr5_-_88956788 1.775 NM_152839
Igj
immunoglobulin joining chain
chr3_+_87422672 1.768 NM_001003912
Arhgef11
Rho guanine nucleotide exchange factor (GEF) 11
chr9_-_73781373 1.765 NM_001081153
Unc13c
unc-13 homolog C (C. elegans)
chr7_-_77511607 1.741 NM_183261
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr8_-_83404377 1.713 NM_021356
Gab1
growth factor receptor bound protein 2-associated protein 1
chr2_+_35547418 1.710 NM_001001602
Dab2ip
disabled homolog 2 (Drosophila) interacting protein
chr14_-_19726121 1.705 NM_144839
Ube2e2
ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
chr2_+_35477498 1.634 NM_001114124
Dab2ip
disabled homolog 2 (Drosophila) interacting protein
chr17_-_82137708 1.621 NM_001112798
NM_011406
Slc8a1

D830013E24Rik
solute carrier family 8 (sodium/calcium exchanger), member 1

RIKEN cDNA D830013E24 gene
chr13_+_74146852 1.610 NM_182839
Tppp
tubulin polymerization promoting protein
chr7_+_56501558 1.594 NM_175272
Nav2
neuron navigator 2
chr15_+_58247016 1.580 NM_145959
D15Ertd621e
DNA segment, Chr 15, ERATO Doi 621, expressed
chr12_-_47919695 1.575 NM_021361
Nova1
neuro-oncological ventral antigen 1
chr8_-_28285056 1.550 NM_001080813
NM_029423
Rab11fip1

RAB11 family interacting protein 1 (class I)

chr4_+_137418151 1.543 NM_199307
Ece1
endothelin converting enzyme 1
chr7_-_107520359 1.537 NM_028292
Ppme1
protein phosphatase methylesterase 1
chr18_+_64500017 1.535 NM_194268
Onecut2
one cut domain, family member 2
chr15_-_103170514 1.508 NM_013866
Zfp385a
zinc finger protein 385A
chr5_+_73882264 1.505 NM_001190733
NM_178896
Dcun1d4

DCN1, defective in cullin neddylation 1, domain containing 4 (S. cerevisiae)

chr4_+_57580989 1.502 NM_172868
Palm2
paralemmin 2
chr2_+_27532692 1.493 NM_011305
Rxra
retinoid X receptor alpha
chr6_+_14851348 1.487 NM_053242
Foxp2
forkhead box P2
chr14_-_106296035 1.441 NM_011897
Spry2
sprouty homolog 2 (Drosophila)
chr6_-_52154455 1.439 NM_010453
Hoxa5
homeobox A5
chr4_+_101091875 1.436 NM_001177602
Ak4
adenylate kinase 4
chr3_+_101180976 1.409 NM_207205
Igsf3
immunoglobulin superfamily, member 3
chr13_-_96020120 1.408 NM_172263
Pde8b
phosphodiesterase 8B
chr17_+_8994520 1.408 NM_011866
Pde10a
phosphodiesterase 10A
chr6_+_15135505 1.396 NM_212435
Foxp2
forkhead box P2
chr11_+_79153388 1.392 NM_010897
Nf1
neurofibromatosis 1
chr11_-_45979836 1.375 NM_172524
Nipal4
NIPA-like domain containing 4
chr2_+_124436031 1.373 NM_172537
NM_199238
NM_199239
NM_199240
NM_199241
Sema6d




sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D




chr14_+_18493380 1.365 NM_001113417
Thrb
thyroid hormone receptor beta
chr17_+_26551909 1.355 NM_001081656
Neurl1b
neuralized homolog 1b (Drosophila)
chr6_-_100237331 1.352 NM_019743
Rybp
RING1 and YY1 binding protein
chr2_+_181498036 1.351 NM_001171615
Myt1
myelin transcription factor 1
chrX_+_135448968 1.349 NM_013724
Nrk
Nik related kinase
chr9_+_118835589 1.341 NM_133710
Ctdspl
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr7_+_25421586 1.332 NM_133743
Lypd3
Ly6/Plaur domain containing 3
chr13_-_64376186 1.322 NM_172587
Cdc14b
CDC14 cell division cycle 14 homolog B (S. cerevisiae)
chr11_-_51570335 1.286 NM_175255
Sec24a
Sec24 related gene family, member A (S. cerevisiae)
chr6_+_66846884 1.271 NM_001177558
Gng12
guanine nucleotide binding protein (G protein), gamma 12
chr17_+_43938789 1.246 NM_207649
Rcan2
regulator of calcineurin 2
chr2_+_156246644 1.242 NM_001003815
NM_013510
Epb4.1l1

erythrocyte protein band 4.1-like 1

chr2_-_168592528 1.229 NM_175303
NM_201395
NM_201396
Sall4


sal-like 4 (Drosophila)


chr9_-_44607274 1.223 NM_027865
Tmem25
transmembrane protein 25
chr10_+_98377759 1.222 NM_026482
Atp2b1
ATPase, Ca++ transporting, plasma membrane 1
chr4_-_91066674 1.218 NM_207685
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr19_+_3851772 1.216 NM_001025566
NM_013490
Chka

choline kinase alpha

chr17_+_44090139 1.202 NM_030598
Rcan2
regulator of calcineurin 2
chr3_+_131748252 1.199 NM_020265
Dkk2
dickkopf homolog 2 (Xenopus laevis)
chr18_-_36675458 1.197 NM_010415
Hbegf
heparin-binding EGF-like growth factor
chr7_-_75893927 1.193 NM_001042592
NM_025549
Arrdc4

arrestin domain containing 4

chr4_+_149656024 1.193 NM_001085492
Rere
arginine glutamic acid dipeptide (RE) repeats
chr10_-_78054639 1.192 NM_027875
Syde1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr16_-_4789869 1.191 NM_025670
5730403B10Rik
RIKEN cDNA 5730403B10 gene
chr3_-_31209216 1.185 NM_172861
Slc7a14
solute carrier family 7 (cationic amino acid transporter, y+ system), member 14
chr2_+_25036276 1.181 NM_025980
Nrarp
Notch-regulated ankyrin repeat protein
chr17_+_75578120 1.171 NM_206958
Ltbp1
latent transforming growth factor beta binding protein 1
chr18_-_23197156 1.166 NM_001161483
Nol4
nucleolar protein 4
chr13_+_31650033 1.165 NM_008239
Foxq1
forkhead box Q1
chr15_-_96886327 1.157 NM_027052
Slc38a4
solute carrier family 38, member 4
chr17_+_57129686 1.152 NM_017393
Clpp
caseinolytic peptidase, ATP-dependent, proteolytic subunit homolog (E. coli)
chr4_-_91038729 1.148 NM_010486
NM_207686
Elavl2

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)

chr10_+_83006673 1.140 NM_001033375
A230046K03Rik
RIKEN cDNA A230046K03 gene
chr11_-_76660476 1.137 NM_007754
Cpd
carboxypeptidase D
chr11_-_68200284 1.113 NM_008744
Ntn1
netrin 1
chr1_+_154246959 1.105 NM_177756
Glt25d2
glycosyltransferase 25 domain containing 2
chr19_-_37281762 1.105 NM_198300
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr6_+_38383918 1.101 NM_177185
Ubn2
ubinuclein 2
chr5_-_103640272 1.089 NM_001081567
NM_009158
Mapk10

mitogen-activated protein kinase 10

chr10_+_7400978 1.081 NM_010690
Lats1
large tumor suppressor
chr1_-_145624156 1.073 NM_013835
Trove2
TROVE domain family, member 2
chr6_+_66846377 1.070 NM_001177556
NM_001177557
NM_001177559
NM_001177560
NM_025278
Gng12




guanine nucleotide binding protein (G protein), gamma 12




chr18_+_10325174 1.068 NM_001083628
Greb1l
growth regulation by estrogen in breast cancer-like
chr7_+_56214442 1.056 NM_001111016
Nav2
neuron navigator 2
chr11_-_87800799 1.055 NM_026556
Dynll2
dynein light chain LC8-type 2
chr6_+_146673451 1.052 NM_172734
Stk38l
serine/threonine kinase 38 like
chr5_-_110877489 1.044 NM_001142642
Fbrsl1
fibrosin-like 1
chr1_-_57028171 1.042 NM_139146
Satb2
special AT-rich sequence binding protein 2
chr6_+_114232618 1.031 NM_178703
Slc6a1
solute carrier family 6 (neurotransmitter transporter, GABA), member 1
chr1_+_62749850 1.031 NM_001077403
NM_001077404
NM_001077405
NM_001077406
NM_001077407
NM_010939
Nrp2





neuropilin 2





chr18_+_43367236 1.016 NM_178749
Stk32a
serine/threonine kinase 32A
chr6_-_92431385 1.013 NM_001134460
Prickle2
prickle homolog 2 (Drosophila)
chr8_-_73905790 0.985 NM_010150
Nr2f6
nuclear receptor subfamily 2, group F, member 6
chr4_-_91042997 0.984 NM_001177883
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr11_-_87811778 0.977 NM_001168471
Dynll2
dynein light chain LC8-type 2
chr11_+_53333270 0.969 NM_033144
Sept8
septin 8
chr9_-_62996767 0.965 NM_001163758
Skor1
SKI family transcriptional corepressor 1
chr8_+_106625524 0.963 NM_009868
Cdh5
cadherin 5
chrX_+_147778717 0.962 NM_198105
Fam120c
family with sequence similarity 120, member C
chr8_+_71404452 0.956 NM_008509
Lpl
lipoprotein lipase
chr1_-_33814590 0.952 NM_145392
Bag2
BCL2-associated athanogene 2
chr6_-_92484838 0.950 NM_001134459
Prickle2
prickle homolog 2 (Drosophila)

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.18 5.74e-12 GO:0048731 system development
2.06 3.34e-11 GO:0048856 anatomical structure development
1.90 3.09e-10 GO:0032502 developmental process
2.06 4.58e-10 GO:0048522 positive regulation of cellular process
1.94 7.59e-10 GO:0007275 multicellular organismal development
1.98 8.22e-10 GO:0048518 positive regulation of biological process
2.65 1.93e-09 GO:0007399 nervous system development
1.91 2.99e-08 GO:0051171 regulation of nitrogen compound metabolic process
1.75 7.62e-08 GO:0031323 regulation of cellular metabolic process
1.87 1.84e-07 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.07 2.07e-07 GO:0030154 cell differentiation
1.86 2.53e-07 GO:0009889 regulation of biosynthetic process
2.64 2.64e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
1.86 2.69e-07 GO:0031326 regulation of cellular biosynthetic process
2.01 8.80e-07 GO:0048869 cellular developmental process
1.92 1.10e-06 GO:0006355 regulation of transcription, DNA-dependent
2.58 1.28e-06 GO:0031328 positive regulation of cellular biosynthetic process
2.64 1.46e-06 GO:0051173 positive regulation of nitrogen compound metabolic process
1.86 1.70e-06 GO:2000112 regulation of cellular macromolecule biosynthetic process
2.08 1.89e-06 GO:0048513 organ development
2.53 2.49e-06 GO:0009891 positive regulation of biosynthetic process
1.84 2.89e-06 GO:0010556 regulation of macromolecule biosynthetic process
1.88 3.01e-06 GO:0051252 regulation of RNA metabolic process
1.68 3.65e-06 GO:0080090 regulation of primary metabolic process
2.62 6.18e-06 GO:0048468 cell development
2.17 6.91e-06 GO:0023051 regulation of signaling
1.68 7.37e-06 GO:0060255 regulation of macromolecule metabolic process
2.71 7.74e-06 GO:0045893 positive regulation of transcription, DNA-dependent
2.61 1.08e-05 GO:0010628 positive regulation of gene expression
2.67 1.20e-05 GO:0051254 positive regulation of RNA metabolic process
2.18 1.45e-05 GO:0009653 anatomical structure morphogenesis
1.78 1.48e-05 GO:0010468 regulation of gene expression
1.59 1.49e-05 GO:0019222 regulation of metabolic process
2.53 1.69e-05 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.15 1.92e-05 GO:0009893 positive regulation of metabolic process
2.49 2.00e-05 GO:0042127 regulation of cell proliferation
2.50 2.60e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
2.18 2.94e-05 GO:0031325 positive regulation of cellular metabolic process
2.63 2.97e-05 GO:0048699 generation of neurons
3.30 3.31e-05 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
2.35 4.22e-05 GO:0050793 regulation of developmental process
2.52 6.28e-05 GO:0022008 neurogenesis
2.80 7.28e-05 GO:0045892 negative regulation of transcription, DNA-dependent
3.67 7.70e-05 GO:0045596 negative regulation of cell differentiation
2.76 1.06e-04 GO:0051253 negative regulation of RNA metabolic process
2.53 1.25e-04 GO:0045595 regulation of cell differentiation
2.42 1.33e-04 GO:2000026 regulation of multicellular organismal development
2.58 1.55e-04 GO:0010558 negative regulation of macromolecule biosynthetic process
2.81 1.60e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.93 1.65e-04 GO:0072358 cardiovascular system development
2.93 1.65e-04 GO:0072359 circulatory system development
1.82 1.67e-04 GO:0048523 negative regulation of cellular process
2.59 3.06e-04 GO:0010629 negative regulation of gene expression
3.12 3.23e-04 GO:0048666 neuron development
1.48 3.88e-04 GO:0044260 cellular macromolecule metabolic process
1.32 4.16e-04 GO:0050794 regulation of cellular process
2.55 4.76e-04 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.06 5.23e-04 GO:0010604 positive regulation of macromolecule metabolic process
3.12 5.43e-04 GO:0060284 regulation of cell development
2.44 6.43e-04 GO:0009890 negative regulation of biosynthetic process
3.13 8.27e-04 GO:0051093 negative regulation of developmental process
2.43 9.88e-04 GO:0031327 negative regulation of cellular biosynthetic process
2.51 1.01e-03 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.08 1.19e-03 GO:0009966 regulation of signal transduction
1.94 1.36e-03 GO:0051239 regulation of multicellular organismal process
2.47 1.44e-03 GO:0051172 negative regulation of nitrogen compound metabolic process
1.42 1.73e-03 GO:0043170 macromolecule metabolic process
2.13 1.84e-03 GO:0010646 regulation of cell communication
1.28 2.17e-03 GO:0065007 biological regulation
3.21 2.61e-03 GO:0031175 neuron projection development
3.19 2.89e-03 GO:0035295 tube development
1.28 3.40e-03 GO:0050789 regulation of biological process
1.68 3.42e-03 GO:0048519 negative regulation of biological process
1.81 3.67e-03 GO:0006351 transcription, DNA-dependent
2.12 3.73e-03 GO:0032879 regulation of localization
1.81 3.90e-03 GO:0032774 RNA biosynthetic process
1.83 4.56e-03 GO:0006464 protein modification process
2.11 5.02e-03 GO:0006796 phosphate metabolic process
2.11 5.30e-03 GO:0006793 phosphorus metabolic process
2.08 5.98e-03 GO:0035556 intracellular signal transduction
2.10 7.33e-03 GO:0010605 negative regulation of macromolecule metabolic process
2.23 7.88e-03 GO:0016310 phosphorylation
2.63 8.11e-03 GO:0043009 chordate embryonic development
2.57 8.30e-03 GO:0051094 positive regulation of developmental process
1.18 8.42e-03 GO:0009987 cellular process
2.35 8.85e-03 GO:0006468 protein phosphorylation
2.56 8.93e-03 GO:0030182 neuron differentiation
2.60 1.06e-02 GO:0009792 embryo development ending in birth or egg hatching
1.77 1.06e-02 GO:0043412 macromolecule modification
1.39 1.10e-02 GO:0032501 multicellular organismal process
3.37 1.20e-02 GO:0048812 neuron projection morphogenesis
2.91 1.34e-02 GO:0008285 negative regulation of cell proliferation
3.10 1.35e-02 GO:0048858 cell projection morphogenesis
7.61 1.35e-02 GO:0043401 steroid hormone mediated signaling pathway
2.97 1.56e-02 GO:0007420 brain development
2.59 1.62e-02 GO:0030030 cell projection organization
2.12 1.74e-02 GO:0009888 tissue development
3.04 1.80e-02 GO:0032990 cell part morphogenesis
2.34 1.86e-02 GO:0007154 cell communication
2.84 1.90e-02 GO:0051960 regulation of nervous system development
6.26 1.94e-02 GO:0009755 hormone-mediated signaling pathway
6.17 2.20e-02 GO:0071383 cellular response to steroid hormone stimulus
3.52 2.25e-02 GO:0071495 cellular response to endogenous stimulus
4.51 2.29e-02 GO:0007411 axon guidance
1.50 2.69e-02 GO:0051179 localization
2.63 2.72e-02 GO:0007417 central nervous system development
5.24 3.22e-02 GO:0010721 negative regulation of cell development
3.59 3.32e-02 GO:0032870 cellular response to hormone stimulus
2.81 3.46e-02 GO:0007167 enzyme linked receptor protein signaling pathway
2.01 3.48e-02 GO:0031324 negative regulation of cellular metabolic process
1.31 4.34e-02 GO:0044237 cellular metabolic process
2.11 4.35e-02 GO:0009790 embryo development
12.94 4.68e-02 GO:0035412 regulation of catenin import into nucleus
1.94 4.87e-02 GO:0009892 negative regulation of metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
3.02 8.09e-07 GO:0043005 neuron projection
1.61 4.34e-06 GO:0071944 cell periphery
1.25 6.19e-06 GO:0005622 intracellular
1.59 1.69e-05 GO:0005886 plasma membrane
1.89 3.10e-05 GO:0044459 plasma membrane part
3.76 4.42e-05 GO:0030424 axon
1.23 1.13e-04 GO:0044424 intracellular part
2.13 1.36e-04 GO:0042995 cell projection
1.14 2.13e-04 GO:0005623 cell
1.14 2.13e-04 GO:0044464 cell part
1.23 2.41e-03 GO:0043229 intracellular organelle
3.11 2.76e-03 GO:0030425 dendrite
10.75 2.99e-03 GO:0032589 neuron projection membrane
1.23 3.04e-03 GO:0043226 organelle
5.91 4.03e-03 GO:0030139 endocytic vesicle
2.90 4.60e-03 GO:0043025 neuronal cell body
4.24 5.53e-03 GO:0033267 axon part
1.36 6.35e-03 GO:0005634 nucleus
2.44 8.09e-03 GO:0045202 synapse
9.02 8.73e-03 GO:0044304 main axon
2.76 9.13e-03 GO:0044297 cell body
16.94 1.22e-02 GO:0030673 axolemma
2.50 1.66e-02 GO:0044463 cell projection part
7.99 1.79e-02 GO:0030666 endocytic vesicle membrane
2.66 2.27e-02 GO:0044456 synapse part
1.22 2.78e-02 GO:0043231 intracellular membrane-bounded organelle
3.56 2.98e-02 GO:0030659 cytoplasmic vesicle membrane
1.22 3.17e-02 GO:0043227 membrane-bounded organelle
3.77 3.40e-02 GO:0019717 synaptosome
1.22 3.80e-02 GO:0005737 cytoplasm
3.45 4.00e-02 GO:0044433 cytoplasmic vesicle part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.34 3.33e-11 GO:0005488 binding
1.54 1.26e-08 GO:0005515 protein binding
2.50 2.54e-06 GO:0030528 transcription regulator activity
1.58 1.04e-04 GO:0043167 ion binding
1.57 1.58e-04 GO:0043169 cation binding
1.57 1.61e-04 GO:0046872 metal ion binding
2.29 1.12e-03 GO:0001071 nucleic acid binding transcription factor activity
2.29 1.12e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
2.34 1.86e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.36 2.27e-03 GO:0043565 sequence-specific DNA binding
2.46 2.70e-03 GO:0004672 protein kinase activity
7.46 3.23e-03 GO:0003707 steroid hormone receptor activity
7.31 3.76e-03 GO:0004879 ligand-dependent nuclear receptor activity
2.45 6.10e-03 GO:0019904 protein domain specific binding
5.75 8.04e-03 GO:0019199 transmembrane receptor protein kinase activity
2.11 9.35e-03 GO:0016301 kinase activity
1.79 1.51e-02 GO:0008270 zinc ion binding
2.83 1.59e-02 GO:0016564 transcription repressor activity
3.31 2.99e-02 GO:0010843 promoter binding
1.62 4.59e-02 GO:0003677 DNA binding