Motif ID: CDX1,2,4.p2

Z-value: 1.341


Transcription factors associated with CDX1,2,4.p2:

Gene SymbolEntrez IDGene Name
Cdx1 12590 caudal type homeobox 1
Cdx2 12591 caudal type homeobox 2
Cdx4 12592 caudal type homeobox 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Cdx1chr18_-_611958520.092.3e-01Click!
Cdx4chrX_+_1005167360.082.6e-01Click!
Cdx2chr5_-_1481186810.083.0e-01Click!


Activity profile for motif CDX1,2,4.p2.

activity profile for motif CDX1,2,4.p2


Sorted Z-values histogram for motif CDX1,2,4.p2

Sorted Z-values for motif CDX1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CDX1,2,4.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr13_-_56280161 17.499 NM_001168615
NM_145976
Tifab

TRAF-interacting protein with forkhead-associated domain, family member B

chr18_+_60963495 16.334 NM_001042605
NM_010545
Cd74

CD74 antigen (invariant polypeptide of major histocompatibility complex, class II antigen-associated)

chr11_+_82988687 15.703 NM_011410
Slfn4
schlafen 4
chr5_+_115373272 15.598 Oasl1
2'-5' oligoadenylate synthetase-like 1
chr3_+_109376824 15.375 NM_146139
Vav3
vav 3 oncogene
chr3_+_95330700 15.184 NM_021281
Ctss
cathepsin S
chr9_-_88626434 14.809 Bcl2a1d
B-cell leukemia/lymphoma 2 related protein A1d
chr11_-_98859189 14.320 Top2a
topoisomerase (DNA) II alpha
chr3_-_15426426 14.289 NM_001002898
Sirpb1a
signal-regulatory protein beta 1A
chr17_+_34442837 13.978 H2-Eb1
histocompatibility 2, class II antigen E beta
chr3_-_15748418 13.531 NM_001173459
LOC100038947
Sirpb1a
signal-regulatory protein beta 1-like
signal-regulatory protein beta 1A
chr19_-_41069024 13.511 NM_008528
Blnk
B-cell linker
chr19_+_12535536 13.043 Mpeg1
macrophage expressed gene 1
chr19_+_12873115 12.694 Lpxn
leupaxin
chr14_+_51748742 12.155 NM_030098
Rnase6
ribonuclease, RNase A family, 6
chr8_+_90812964 12.092 NM_001037723
Adcy7
adenylate cyclase 7
chr1_+_175560938 11.711 NM_175026
Pyhin1
pyrin and HIN domain family, member 1
chr19_+_53403902 11.656 NM_010847
Mxi1
Max interacting protein 1
chr10_-_88875526 11.302 Gas2l3
growth arrest-specific 2 like 3
chrX_+_103338609 11.191 NM_205820
Tlr13
toll-like receptor 13
chr1_+_132762248 11.164 Faim3
Fas apoptotic inhibitory molecule 3
chr6_-_70067577 11.138 Gm10883
predicted gene 10883
chr5_+_115373246 11.111 NM_145209
Oasl1
2'-5' oligoadenylate synthetase-like 1
chr6_-_129572590 11.108 NM_033078
Klrk1
killer cell lectin-like receptor subfamily K, member 1
chr19_+_12535268 11.096 NM_010821
Mpeg1
macrophage expressed gene 1
chr17_+_34442808 10.690 NM_010382
H2-Eb1
histocompatibility 2, class II antigen E beta
chr2_+_163899842 10.576 NM_021420
Stk4
serine/threonine kinase 4
chr5_+_90919768 10.545 Afp
alpha fetoprotein
chr15_+_102289600 10.431 NM_001170911
NM_025385
Prr13

proline rich 13

chr14_-_56407622 10.329 NM_001164107
NM_001164108
NM_019955
Ripk3


receptor-interacting serine-threonine kinase 3


chr2_-_122420914 10.056 Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr16_-_4679664 9.979 NM_030205
Coro7
coronin 7
chr15_+_103284200 9.914 NM_153505
Nckap1l
NCK associated protein 1 like
chr18_-_35900005 9.528 NM_028261
Tmem173
transmembrane protein 173
chr11_+_87569075 9.331 A430104N18Rik
RIKEN cDNA A430104N18 gene
chr17_+_37006518 9.274 NM_011280
Trim10
tripartite motif-containing 10
chr1_+_132762353 9.109 NM_026976
Faim3
Fas apoptotic inhibitory molecule 3
chr19_+_12873063 9.020 NM_134152
Lpxn
leupaxin
chr1_+_173847645 8.977 NM_030710
Slamf6
SLAM family member 6
chr7_-_25873560 8.946


chr5_-_92776160 8.757 Cxcl10
chemokine (C-X-C motif) ligand 10
chrX_-_9030859 8.591 Cybb
cytochrome b-245, beta polypeptide
chr10_-_61960613 8.580 Srgn
serglycin
chr19_+_3935169 8.536 NM_001161428
NM_019449
Unc93b1

unc-93 homolog B1 (C. elegans)

chr5_-_134705423 8.466 NM_010876
Ncf1
neutrophil cytosolic factor 1
chr5_+_90919758 7.928 Afp
alpha fetoprotein
chr11_-_83388330 7.593 Ccl9
chemokine (C-C motif) ligand 9
chr4_-_46579311 7.553 NM_178893
Coro2a
coronin, actin binding protein 2A
chr19_-_30623890 7.493 NM_010051
Dkk1
dickkopf homolog 1 (Xenopus laevis)
chr7_+_109614267 7.478 Rrm1
ribonucleotide reductase M1
chr2_+_84820615 7.376 NM_008920
Prg2
proteoglycan 2, bone marrow
chr10_-_111434265 7.369 NM_028608
Glipr1
GLI pathogenesis-related 1 (glioma)
chr7_+_117916117 7.317 NM_009667
Ampd3
adenosine monophosphate deaminase 3
chr17_-_32557916 7.257 NM_021319
Pglyrp2
peptidoglycan recognition protein 2
chr15_+_102126686 7.222 NM_001014976
Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr10_-_111434231 7.168 Glipr1
GLI pathogenesis-related 1 (glioma)
chr14_+_78304045 7.108 NM_029495
NM_178825
Epsti1

epithelial stromal interaction 1 (breast)

chr5_+_136559785 7.059 NM_001039103
NM_133914
Rasa4

RAS p21 protein activator 4

chr16_+_45224449 6.860 NM_001037719
NM_177584
Btla

B and T lymphocyte associated

chr4_-_132352272 6.851 NM_001033308
BC013712
cDNA sequence BC013712
chr11_+_83037063 6.702 AI662270
expressed sequence AI662270
chr4_-_133650937 6.572 NM_013706
Cd52
CD52 antigen
chr13_-_51829951 6.466 Sema4d
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D
chr19_-_41068625 6.463 Blnk
B-cell linker
chr9_-_21767872 6.426 NM_010149
Epor
erythropoietin receptor
chr7_+_4225744 6.341 NM_011093
NM_008848
Pira6

paired-Ig-like receptor A6

chr9_+_89094190 6.335 Bcl2a1a
B-cell leukemia/lymphoma 2 related protein A1a
chr16_-_32165509 6.170 NM_146069
Lrrc33
leucine rich repeat containing 33
chr11_+_100442602 6.147 Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr5_+_145888588 6.123 Arpc1b
actin related protein 2/3 complex, subunit 1B
chr6_-_122560002 6.050 Gdf3
growth differentiation factor 3
chr5_-_17355533 6.036 NM_001159556
NM_001159557
Cd36

CD36 antigen

chr7_-_3796619 6.023 Pira1
Pira2
Lilrb3
paired-Ig-like receptor A1
paired-Ig-like receptor A2
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 3
chr5_-_123183537 5.918 Camkk2
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr1_+_133535033 5.917 Ctse
cathepsin E
chr2_+_129442079 5.915 Sirpa
signal-regulatory protein alpha
chr11_+_106612525 5.904 NM_001033435
Gm885
predicted gene 885
chr19_+_11518042 5.848 NM_021718
Ms4a4b
membrane-spanning 4-domains, subfamily A, member 4B
chr19_+_11592938 5.754 NM_027209
Ms4a6b
membrane-spanning 4-domains, subfamily A, member 6B
chr7_-_148452299 5.694 NM_016850
Irf7
interferon regulatory factor 7
chr3_-_144595486 5.631 NM_001033199
AI747448
expressed sequence AI747448
chr10_+_57370786 5.620 NM_001039050
NM_001190402
Pkib

protein kinase inhibitor beta, cAMP dependent, testis specific

chr9_+_21142267 5.612 NM_152808
Slc44a2
solute carrier family 44, member 2
chr4_+_102242664 5.472 NM_001177980
Pde4b
phosphodiesterase 4B, cAMP specific
chr5_-_17341534 5.453 Cd36
CD36 antigen
chr6_-_130287518 5.402 NM_010648
Klra3
killer cell lectin-like receptor, subfamily A, member 3
chr9_-_66767436 5.356 NM_173413
Rab8b
RAB8B, member RAS oncogene family
chr1_-_175805812 5.348 Mndal
myeloid nuclear differentiation antigen like
chr1_-_173579057 5.258 Slamf7
SLAM family member 7
chr15_+_102126735 5.249 Espl1
extra spindle poles-like 1 (S. cerevisiae)
chr9_-_96379093 5.232 Rnf7
ring finger protein 7
chr1_-_167638156 5.184 NM_001038846
NM_178593
Rcsd1

RCSD domain containing 1

chr7_-_113358823 5.183 NM_001039160
NM_029000
Gvin1

GTPase, very large interferon inducible 1

chr7_-_113102453 5.183 NM_001039160
NM_029000
Gvin1

GTPase, very large interferon inducible 1

chr7_+_134439804 5.167 NM_008400
Itgal
integrin alpha L
chr7_-_21288567 5.165 NM_001167155
NM_001167154
Gm4144
Gm8693
predicted gene 4144
predicted gene 8693
chr5_+_86500770 5.162 NM_019992
Stap1
signal transducing adaptor family member 1
chr1_+_173612132 5.151 Cd48
CD48 antigen
chr12_+_109843975 5.142 NM_001163395
Evl
Ena-vasodilator stimulated phosphoprotein
chr16_-_75909440 5.134 NM_023380
Samsn1
SAM domain, SH3 domain and nuclear localization signals, 1
chr14_+_48092244 5.113 Fbxo34
F-box protein 34
chr6_-_122560022 5.098 NM_008108
Gdf3
growth differentiation factor 3
chr14_+_48092305 5.080 Fbxo34
F-box protein 34
chr17_+_35189798 4.899


chr6_+_128837604 4.838 NM_020257
Clec2i
C-type lectin domain family 2, member i
chr5_-_88956788 4.808 NM_152839
Igj
immunoglobulin joining chain
chr11_+_62413710 4.783


chr18_-_36926866 4.748


chr12_+_82049290 4.716 Srsf5
serine/arginine-rich splicing factor 5
chr11_-_83462722 4.714 NM_011337
Ccl3
chemokine (C-C motif) ligand 3
chr2_-_27118325 4.696 Vav2
vav 2 oncogene
chr7_-_23477335 4.677 NM_001167155
NM_001167154
Gm4144
Gm8693
predicted gene 4144
predicted gene 8693
chr12_-_115170216 4.654 Ighg
Immunoglobulin heavy chain (gamma polypeptide)
chr9_-_14185685 4.624 NM_028013
Endod1
endonuclease domain containing 1
chr8_+_119983664 4.624


chr1_+_173612173 4.575 NM_007649
Cd48
CD48 antigen
chr12_-_27129497 4.543 Rsad2
radical S-adenosyl methionine domain containing 2
chr13_-_67500685 4.536 NM_001080941
Zfp429
zinc finger protein 429
chr19_+_36453556 4.511 NM_029508
Pcgf5
polycomb group ring finger 5
chr7_-_22813915 4.500 NM_001166839
NM_001167169
NM_001167168
NM_001166746
Gm4172
Gm4179
Gm4220
Vmn1r111
predicted gene 4172
predicted gene 4179
predicted gene 4220
vomeronasal 1 receptor 111
chr9_+_7272513 4.460 NM_008607
Mmp13
matrix metallopeptidase 13
chr13_+_24706474 4.436 NM_178658
Fam65b
family with sequence similarity 65, member B
chr14_-_103379725 4.377 Kctd12
potassium channel tetramerisation domain containing 12
chr11_+_60955985 4.365 Tnfrsf13b
tumor necrosis factor receptor superfamily, member 13b
chr3_-_112959644 4.346 NM_001190403
NM_001190404
Amy2b

amylase 2b

chr11_-_34647110 4.320 NM_027411
Ccdc99
coiled-coil domain containing 99
chr4_+_135728188 4.311 NM_177733
E2f2
E2F transcription factor 2
chr7_+_29225955 4.307 NM_001039192
Gmfg
glia maturation factor, gamma
chr10_+_79457716 4.277 Cnn2
calponin 2
chr2_+_24242134 4.272 Psd4
pleckstrin and Sec7 domain containing 4
chr10_+_79348991 4.266 NM_015779
Elane
elastase, neutrophil expressed
chr1_-_173582969 4.240 NM_144539
Slamf7
SLAM family member 7
chr12_-_80084464 4.206 NM_001170401
Tmem229b
transmembrane protein 229B
chr14_-_20796255 4.206 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr1_-_55044032 4.197 Sf3b1
splicing factor 3b, subunit 1
chr1_-_167638124 4.183 Rcsd1
RCSD domain containing 1
chr1_-_192994532 4.172 Atf3
activating transcription factor 3
chr1_+_109407998 4.138 NM_001174170
NM_011111
Serpinb2

serine (or cysteine) peptidase inhibitor, clade B, member 2

chr5_-_17341512 4.135 Cd36
CD36 antigen
chr1_-_53813191 4.120


chr11_-_115375672 4.104 NM_008258
Hn1
hematological and neurological expressed sequence 1
chr7_-_3820753 4.085 Gm10693
predicted pseudogene 10693
chr3_-_113094211 4.069 NM_001160150
NM_001160151
NM_001160152
NM_001042711
Amy2a4
Amy2a3
Amy2a2
Amy2a5
amylase 2a4
amylase 2a3
amylase 2a2
amylase 2a5
chr5_+_34868420 4.054 NM_011893
Sh3bp2
SH3-domain binding protein 2
chr17_+_34375847 4.052 NM_010389
H2-Ob
histocompatibility 2, O region beta locus
chr9_+_124016886 4.046 NM_009915
Ccr2
chemokine (C-C motif) receptor 2
chr6_-_129422702 4.025 NM_020008
Clec7a
C-type lectin domain family 7, member a
chr3_-_113126814 4.022 NM_001160150
NM_001160151
NM_001160152
NM_001042711
Amy2a4
Amy2a3
Amy2a2
Amy2a5
amylase 2a4
amylase 2a3
amylase 2a2
amylase 2a5
chr5_-_17394564 4.021 Cd36
CD36 antigen
chr10_+_57351786 3.996 NM_001039051
NM_008863
Pkib

protein kinase inhibitor beta, cAMP dependent, testis specific

chr11_-_98862163 3.991 Top2a
topoisomerase (DNA) II alpha
chr3_+_145813137 3.990 NM_001005846
Mcoln2
mucolipin 2
chr17_+_48594225 3.974 NM_152823
Unc5cl
unc-5 homolog C (C. elegans)-like
chr7_-_21488234 3.960 NM_001166839
NM_001167169
NM_001167168
NM_001166746
Gm4172
Gm4179
Gm4220
Vmn1r111
predicted gene 4172
predicted gene 4179
predicted gene 4220
vomeronasal 1 receptor 111
chr7_-_24036700 3.960 NM_001166839
NM_001167169
NM_001167168
NM_001166746
Gm4172
Gm4179
Gm4220
Vmn1r111
predicted gene 4172
predicted gene 4179
predicted gene 4220
vomeronasal 1 receptor 111
chr1_+_60803231 3.938 NM_007642
Cd28
CD28 antigen
chr7_-_3796651 3.923 NM_011089
Pira2
paired-Ig-like receptor A2
chr5_-_105411580 3.920 NM_030239
Abcg3
ATP-binding cassette, sub-family G (WHITE), member 3
chr14_-_20796411 3.896 NM_001038637
NM_010315
Gng2

guanine nucleotide binding protein (G protein), gamma 2

chr4_+_44313764 3.885 NM_010790
Melk
maternal embryonic leucine zipper kinase
chr8_+_34763709 3.871 NM_010344
Gsr
glutathione reductase
chr10_+_66648458 3.867 Jmjd1c
jumonji domain containing 1C
chr4_+_44313865 3.854 Melk
maternal embryonic leucine zipper kinase
chr3_+_145784635 3.850 NM_134160
Mcoln3
mucolipin 3
chr8_+_74121544 3.849 NM_001166213
Fam129c
family with sequence similarity 129, member C
chr7_+_29222465 3.827 NM_022024
Gmfg
glia maturation factor, gamma
chr1_-_64167818 3.825 Klf7
Kruppel-like factor 7 (ubiquitous)
chr11_-_83391984 3.819 Ccl9
chemokine (C-C motif) ligand 9
chr10_-_61970481 3.817 NM_011157
Srgn
serglycin
chr17_-_32557807 3.804 Pglyrp2
peptidoglycan recognition protein 2
chr3_+_95465860 3.790 Mcl1
myeloid cell leukemia sequence 1
chr7_+_28954717 3.789 NM_007991
Fbl
fibrillarin
chr11_+_100442831 3.787 Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr2_-_148263617 3.743 Cd93
CD93 antigen
chr15_-_82074765 3.728 NM_001080158
Cenpm
centromere protein M
chr7_+_22057197 3.710 NM_001166740
Vmn1r125
vomeronasal 1 receptor 125
chr6_+_116123984 3.706 Gm8203
predicted pseudogene 8203
chr5_+_34014563 3.682


chr16_+_36184297 3.665 NM_001082547
Gm5483
predicted gene 5483
chr9_-_123771243 3.647 NM_011798
Xcr1
chemokine (C motif) receptor 1
chr8_+_72332573 3.631 NM_198101
Gmip
Gem-interacting protein
chr7_+_23656242 3.623 NM_001166724
Vmn1r160
vomeronasal 1 receptor 160
chr6_+_83065466 3.620 NM_020619
Mogs
mannosyl-oligosaccharide glucosidase
chr14_-_20796199 3.610 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr13_-_101086551 3.608 NM_010871
Naip6
NLR family, apoptosis inhibitory protein 6
chr4_-_46417054 3.605 NM_053149
Hemgn
hemogen
chr5_+_114580397 3.602 NM_001040691
Ung
uracil DNA glycosylase
chr5_+_150076605 3.586 NM_009663
Alox5ap
arachidonate 5-lipoxygenase activating protein
chrX_+_83115611 3.575 NM_001163539
5430427O19Rik
RIKEN cDNA 5430427O19 gene
chr7_-_22331108 3.569 NM_001166839
NM_001167169
NM_001167168
NM_001166746
Gm4172
Gm4179
Gm4220
Vmn1r111
predicted gene 4172
predicted gene 4179
predicted gene 4220
vomeronasal 1 receptor 111
chr3_-_113159420 3.560 NM_001160150
NM_001160151
NM_001160152
NM_001042711
Amy2a4
Amy2a3
Amy2a2
Amy2a5
amylase 2a4
amylase 2a3
amylase 2a2
amylase 2a5
chr11_-_34647016 3.544 Ccdc99
coiled-coil domain containing 99
chr7_+_63185457 3.521 Cyfip1
cytoplasmic FMR1 interacting protein 1
chr8_+_85689250 3.515 NM_001111304
NM_027758
Tbc1d9

TBC1 domain family, member 9

chr14_-_122314994 3.507 NM_182806
Gpr18
G protein-coupled receptor 18
chr7_-_21697365 3.500 NM_001167151
NM_001167150
NM_001166742
Gm4498
Gm8453
Vmn1r118
predicted gene 4498
predicted gene 8453
vomeronasal 1 receptor 118
chr14_-_52780511 3.452 Supt16h
suppressor of Ty 16 homolog (S. cerevisiae)
chr17_+_34282215 3.450 NM_010388
H2-DMb1
H2-DMb2
histocompatibility 2, class II, locus Mb1
histocompatibility 2, class II, locus Mb2
chr9_-_82826139 3.431 Phip
pleckstrin homology domain interacting protein
chr7_-_23628623 3.425 NM_001166758
Vmn1r159
vomeronasal 1 receptor 159

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.61 1.34e-05 GO:0002376 immune system process
1.77 1.10e-04 GO:0006396 RNA processing
2.09 1.36e-04 GO:0008380 RNA splicing
1.25 1.29e-02 GO:0090304 nucleic acid metabolic process
1.62 2.13e-02 GO:0006952 defense response
9.77 3.16e-02 GO:0001878 response to yeast
4.65 4.23e-02 GO:0002478 antigen processing and presentation of exogenous peptide antigen

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.45 9.62e-08 GO:0044428 nuclear part
1.80 2.44e-05 GO:0030529 ribonucleoprotein complex
1.20 2.71e-05 GO:0005634 nucleus
1.42 4.93e-05 GO:0031981 nuclear lumen
1.23 1.35e-03 GO:0032991 macromolecular complex
2.26 4.56e-03 GO:0005681 spliceosomal complex
1.96 4.97e-03 GO:0009897 external side of plasma membrane
1.31 6.15e-03 GO:0070013 intracellular organelle lumen
1.31 6.53e-03 GO:0031974 membrane-enclosed lumen
1.31 6.95e-03 GO:0043233 organelle lumen
1.41 8.06e-03 GO:0005654 nucleoplasm
2.57 1.64e-02 GO:0071013 catalytic step 2 spliceosome

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.25 4.70e-03 GO:0003676 nucleic acid binding
1.49 1.12e-02 GO:0003723 RNA binding