Motif ID: CGUGUCU

Z-value: 0.320


Mature miRNA associated with seed CGUGUCU:

NamemiRBase Accession
mmu-miR-187 MIMAT0000216



Activity profile for motif CGUGUCU.

activity profile for motif CGUGUCU


Sorted Z-values histogram for motif CGUGUCU

Sorted Z-values for motif CGUGUCU



Network of associatons between targets according to the STRING database.



First level regulatory network of CGUGUCU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr7_+_129432585 2.341 NM_008855
Prkcb
protein kinase C, beta
chr3_-_126646303 2.135 NM_001034168
Ank2
ankyrin 2, brain
chr6_+_108610606 2.133 NM_011498
Bhlhe40
basic helix-loop-helix family, member e40
chr14_-_66832383 2.026 NM_001162366
Ptk2b
PTK2 protein tyrosine kinase 2 beta
chr5_+_130845319 1.864 NM_181045
Caln1
calneuron 1
chr2_+_156246644 1.835 NM_001003815
NM_013510
Epb4.1l1

erythrocyte protein band 4.1-like 1

chr4_+_118781336 1.811 NM_011400
Slc2a1
solute carrier family 2 (facilitated glucose transporter), member 1
chr14_-_66899764 1.761 NM_001162365
NM_172498
Ptk2b

PTK2 protein tyrosine kinase 2 beta

chr6_-_113841356 1.721 NM_001036684
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr15_-_91403685 1.673 NM_001033633
Slc2a13
solute carrier family 2 (facilitated glucose transporter), member 13
chr3_-_126701367 1.672 NM_178655
Ank2
ankyrin 2, brain
chr6_-_113991945 1.649 NM_009723
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr5_+_130924661 1.644 NM_021371
Caln1
calneuron 1
chr3_+_136333733 1.633 NM_008913
Ppp3ca
protein phosphatase 3, catalytic subunit, alpha isoform
chr3_+_127492716 1.613 NM_145133
Tifa
TRAF-interacting protein with forkhead-associated domain
chr10_-_108447674 1.276 NM_009306
Syt1
synaptotagmin I
chrX_+_38754480 1.257 NM_016886
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr2_+_156301543 1.153 NM_001006664
Epb4.1l1
erythrocyte protein band 4.1-like 1
chr17_-_25073897 1.073 NM_001163447
NM_001163448
NM_001163449
NM_001163450
NM_001163451
NM_001163453
NM_013931
Mapk8ip3






mitogen-activated protein kinase 8 interacting protein 3






chr7_-_116651647 1.051 NM_001170912
NM_181853
Trim66

tripartite motif-containing 66

chr17_-_46162111 0.951 NM_001110266
NM_001110267
NM_001110268
Vegfa


vascular endothelial growth factor A


chr13_+_9275741 0.860 NM_001081426
Dip2c
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr11_-_80966253 0.853 NM_007384
Accn1
amiloride-sensitive cation channel 1, neuronal (degenerin)
chr14_-_37948251 0.835 NM_078478
Ghitm
growth hormone inducible transmembrane protein
chr11_-_81781897 0.832 NM_001034013
Accn1
amiloride-sensitive cation channel 1, neuronal (degenerin)
chrX_+_143397055 0.821 NM_008312
Htr2c
5-hydroxytryptamine (serotonin) receptor 2C
chr10_-_52101880 0.775 NM_053187
Gopc
golgi associated PDZ and coiled-coil motif containing
chr13_+_5860701 0.769 NM_011803
Klf6
Kruppel-like factor 6
chr1_-_156946739 0.756 NM_010500
Ier5
immediate early response 5
chr5_-_135028197 0.752 NM_001039162
NM_009990
Clip2

CAP-GLY domain containing linker protein 2

chr17_-_23877115 0.720 NM_023824
Paqr4
progestin and adipoQ receptor family member IV
chr16_-_55838747 0.716 NM_001159395
NM_030612
Nfkbiz

nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta

chr18_-_72510670 0.670 NM_007831
Dcc
deleted in colorectal carcinoma
chr4_+_13711928 0.636 NM_009822
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr5_+_98609872 0.594 NM_029947
Prdm8
PR domain containing 8
chr6_-_89312545 0.574 NM_008881
Plxna1
plexin A1
chr4_+_13670425 0.536 NM_001111026
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr4_+_150229178 0.513 NM_133753
Errfi1
ERBB receptor feedback inhibitor 1
chr7_-_116637251 0.505 NM_001170913
Trim66
tripartite motif-containing 66
chr17_-_46169322 0.487 NM_001025250
NM_001025257
NM_009505
Vegfa


vascular endothelial growth factor A


chr10_+_79256298 0.484 NM_001161747
NM_023128
Palm

paralemmin

chr16_-_55822217 0.474 NM_001159394
Nfkbiz
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta
chr1_-_40847501 0.473 NM_172499
Mfsd9
major facilitator superfamily domain containing 9
chr2_+_118727248 0.464 NM_001045523
Bahd1
bromo adjacent homology domain containing 1
chr2_-_155518064 0.436 NM_001163452
NM_019828
Trpc4ap

transient receptor potential cation channel, subfamily C, member 4 associated protein

chr16_+_17406078 0.322 NM_023348
Snap29
synaptosomal-associated protein 29
chr1_-_58642994 0.274 NM_172513
Fam126b
family with sequence similarity 126, member B
chr10_-_14264800 0.256 NM_001002268
Gpr126
G protein-coupled receptor 126
chr12_+_70473032 0.253 NM_007481
Arf6
ADP-ribosylation factor 6
chr14_+_8650470 0.230 NM_134080
Flnb
filamin, beta
chr2_+_163820920 0.172 NM_018753
Ywhab
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr17_+_28369642 0.152 NM_011145
Ppard
peroxisome proliferator activator receptor delta
chr5_+_139865857 0.151 NM_001038703
Gpr146
G protein-coupled receptor 146
chr12_+_78339999 0.137 NM_016893
Fut8
fucosyltransferase 8
chr17_+_78599556 0.134 NM_015800
Crim1
cysteine rich transmembrane BMP regulator 1 (chordin like)
chr4_+_13678443 0.128 NM_001111027
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr19_-_37281762 0.122 NM_198300
Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr5_+_139856534 0.118 NM_030258
Gpr146
G protein-coupled receptor 146
chr2_-_44717141 0.110 NM_172662
Gtdc1
glycosyltransferase-like domain containing 1
chr2_-_167457476 0.096 NM_023230
Ube2v1
ubiquitin-conjugating enzyme E2 variant 1
chr13_-_102462584 0.095 NM_001024955
Pik3r1
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr6_-_113145321 0.077 NM_177763
Lhfpl4
lipoma HMGIC fusion partner-like protein 4
chr7_-_87550315 0.038 NM_001081454
Furin
furin (paired basic amino acid cleaving enzyme)
chr17_+_43526389 0.020 NM_001081178
Gpr116
G protein-coupled receptor 116

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
3.15 1.98e-05 GO:0051179 localization
4.87 1.74e-03 GO:0032879 regulation of localization
4.08 1.83e-03 GO:0023051 regulation of signaling
2.84 9.02e-03 GO:0006810 transport
2.80 1.13e-02 GO:0051234 establishment of localization
2.47 1.20e-02 GO:0031323 regulation of cellular metabolic process
3.68 1.34e-02 GO:0051239 regulation of multicellular organismal process
1.78 1.50e-02 GO:0050794 regulation of cellular process
1.73 1.68e-02 GO:0050789 regulation of biological process
3.29 2.18e-02 GO:0065008 regulation of biological quality
2.29 2.35e-02 GO:0019222 regulation of metabolic process
6.59 3.75e-02 GO:0006873 cellular ion homeostasis
2.37 3.83e-02 GO:0080090 regulation of primary metabolic process
4.25 4.09e-02 GO:0031324 negative regulation of cellular metabolic process
6.42 4.41e-02 GO:0055082 cellular chemical homeostasis
5.40 4.46e-02 GO:0048878 chemical homeostasis
32.72 4.84e-02 GO:0048286 lung alveolus development
1.66 4.97e-02 GO:0065007 biological regulation

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
3.18 9.67e-08 GO:0005886 plasma membrane
3.12 1.57e-07 GO:0071944 cell periphery
3.43 1.46e-03 GO:0044459 plasma membrane part
1.73 3.84e-03 GO:0016020 membrane
10.45 1.16e-02 GO:0045121 membrane raft
1.77 2.05e-02 GO:0044425 membrane part
4.16 2.56e-02 GO:0005624 membrane fraction
3.75 2.60e-02 GO:0042995 cell projection
3.98 3.60e-02 GO:0005626 insoluble fraction
1.28 3.88e-02 GO:0005623 cell
1.28 3.88e-02 GO:0044464 cell part
11.56 4.08e-02 GO:0019717 synaptosome
4.97 4.80e-02 GO:0043005 neuron projection
3.46 4.90e-02 GO:0000267 cell fraction

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
2.35 5.23e-06 GO:0005515 protein binding
7.87 9.25e-03 GO:0019900 kinase binding
4.31 1.67e-02 GO:0019899 enzyme binding
12.78 2.35e-02 GO:0005516 calmodulin binding
65.41 3.70e-02 GO:0005161 platelet-derived growth factor receptor binding
7.84 3.73e-02 GO:0019901 protein kinase binding
1.46 4.02e-02 GO:0005488 binding