Motif ID: CREB1.p2

Z-value: 1.247


Transcription factors associated with CREB1.p2:

Gene SymbolEntrez IDGene Name
Creb1 12912 cAMP responsive element binding protein 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Creb1chr1_+_645795590.425.1e-09Click!


Activity profile for motif CREB1.p2.

activity profile for motif CREB1.p2


Sorted Z-values histogram for motif CREB1.p2

Sorted Z-values for motif CREB1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CREB1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_13338741 14.173 Tfdp1
transcription factor Dp 1
chr18_+_11815869 13.941 Rbbp8
retinoblastoma binding protein 8
chr3_-_19211000 13.566 NM_001122759
 Pde7a
phosphodiesterase 7A
chr6_-_88848650 13.365 NM_008564
 Mcm2
minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr7_-_31449991 12.848 NM_027999
 Haus5
HAUS augmin-like complex, subunit 5
chr2_+_35992148 11.968 Mrrf
mitochondrial ribosome recycling factor
chr19_-_4625574 11.356 NM_023131
 Rce1
RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
chr19_-_4625276 10.949 Rce1
RCE1 homolog, prenyl protein peptidase (S. cerevisiae)
chr3_-_36470904 10.712 NM_009828
 Ccna2
cyclin A2
chr11_-_76057153 10.355 Glod4
glyoxalase domain containing 4
chr3_-_36470845 10.174 Ccna2
cyclin A2
chr7_-_31449951 9.936 Haus5
HAUS augmin-like complex, subunit 5
chr4_-_133801438 9.781 NM_024215
 Zfp593
zinc finger protein 593
chr12_+_113883038 9.407 NM_001161737
NM_013929
 Siva1

SIVA1, apoptosis-inducing factor

chr3_+_134875526 9.305 NM_173762
 Cenpe
centromere protein E
chr3_-_36470882 9.104 Ccna2
cyclin A2
chr9_-_64020685 8.860 NM_026507
 Zwilch
Zwilch, kinetochore associated, homolog (Drosophila)
chr17_-_71660199 8.766 NM_145158
 Emilin2
elastin microfibril interfacer 2
chr15_+_100058249 8.750 NM_007497
 Atf1
activating transcription factor 1
chr11_-_76057188 8.630 NM_026029
 Glod4
glyoxalase domain containing 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 104 entries
Enrichment   P-value GO Accession GO Term
6.43 3.41e-02 GO:0032392 DNA geometric change
3.97 4.06e-04 GO:0050657 nucleic acid transport
3.97 4.06e-04 GO:0050658 RNA transport
3.97 4.06e-04 GO:0051236 establishment of RNA localization
3.94 3.85e-02 GO:0000082 G1/S transition of mitotic cell cycle
3.82 7.75e-04 GO:0006403 RNA localization
3.77 1.59e-02 GO:0006302 double-strand break repair
3.73 9.17e-03 GO:0051028 mRNA transport
3.55 3.50e-02 GO:0010212 response to ionizing radiation
3.38 1.72e-03 GO:0051329 interphase of mitotic cell cycle
3.36 6.32e-03 GO:0015931 nucleobase, nucleoside, nucleotide and nucleic acid transport
3.28 2.88e-03 GO:0051325 interphase
3.24 1.24e-05 GO:0006260 DNA replication
2.95 2.76e-02 GO:0071103 DNA conformation change
2.94 4.84e-02 GO:0007059 chromosome segregation
2.76 3.06e-02 GO:0042254 ribosome biogenesis
2.58 5.97e-03 GO:0034470 ncRNA processing
2.53 8.36e-03 GO:0022613 ribonucleoprotein complex biogenesis
2.49 1.77e-02 GO:0007346 regulation of mitotic cell cycle
2.46 3.71e-03 GO:0010564 regulation of cell cycle process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 35 entries
Enrichment   P-value GO Accession GO Term
3.02 4.06e-02 GO:0071013 catalytic step 2 spliceosome
2.62 1.13e-02 GO:0000775 chromosome, centromeric region
2.55 1.79e-02 GO:0016604 nuclear body
2.33 6.11e-19 GO:0005654 nucleoplasm
2.28 4.86e-02 GO:0005840 ribosome
2.27 1.59e-04 GO:0005667 transcription factor complex
2.22 2.34e-10 GO:0044451 nucleoplasm part
2.18 2.50e-28 GO:0044428 nuclear part
2.16 3.20e-06 GO:0030529 ribonucleoprotein complex
2.15 1.27e-21 GO:0031981 nuclear lumen
2.15 1.25e-04 GO:0005730 nucleolus
2.10 2.52e-05 GO:0005694 chromosome
2.08 1.87e-22 GO:0070013 intracellular organelle lumen
2.07 8.80e-23 GO:0031974 membrane-enclosed lumen
2.07 2.38e-22 GO:0043233 organelle lumen
1.96 1.52e-03 GO:0044427 chromosomal part
1.80 4.01e-50 GO:0005634 nucleus
1.63 5.96e-24 GO:0044446 intracellular organelle part
1.62 9.57e-24 GO:0044422 organelle part
1.58 4.32e-60 GO:0043231 intracellular membrane-bounded organelle

Gene overrepresentation in function category:

Showing 1 to 20 of 32 entries
Enrichment   P-value GO Accession GO Term
6.03 4.19e-03 GO:0035064 methylated histone residue binding
4.50 7.56e-04 GO:0003697 single-stranded DNA binding
3.09 4.41e-02 GO:0008026 ATP-dependent helicase activity
3.09 4.41e-02 GO:0070035 purine NTP-dependent helicase activity
2.75 3.93e-05 GO:0043566 structure-specific DNA binding
2.75 1.86e-02 GO:0003735 structural constituent of ribosome
2.45 3.30e-02 GO:0000287 magnesium ion binding
2.13 2.07e-03 GO:0008134 transcription factor binding
2.11 7.07e-09 GO:0003723 RNA binding
1.91 4.77e-27 GO:0003676 nucleic acid binding
1.87 8.01e-16 GO:0003677 DNA binding
1.82 4.14e-05 GO:0001071 nucleic acid binding transcription factor activity
1.82 4.14e-05 GO:0003700 sequence-specific DNA binding transcription factor activity
1.76 2.30e-05 GO:0030528 transcription regulator activity
1.75 2.14e-03 GO:0043565 sequence-specific DNA binding
1.73 1.24e-08 GO:0005524 ATP binding
1.71 2.39e-13 GO:0000166 nucleotide binding
1.71 2.37e-10 GO:0035639 purine ribonucleoside triphosphate binding
1.71 1.81e-08 GO:0030554 adenyl nucleotide binding
1.70 4.62e-08 GO:0032559 adenyl ribonucleotide binding