Motif ID: CTCF.p2

Z-value: 1.691


Transcription factors associated with CTCF.p2:

Gene SymbolEntrez IDGene Name
Ctcf 13018 CCCTC-binding factor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ctcfchr8_+_1081604370.222.9e-03Click!


Activity profile for motif CTCF.p2.

activity profile for motif CTCF.p2


Sorted Z-values histogram for motif CTCF.p2

Sorted Z-values for motif CTCF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of CTCF.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_26212588 16.271 Plekha2
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr7_+_26471968 14.473 NM_011577
 Tgfb1
transforming growth factor, beta 1
chr11_+_68245608 12.976 NM_177320
 Pik3r5
phosphoinositide-3-kinase, regulatory subunit 5, p101
chr3_-_107499129 12.399 Ahcyl1
S-adenosylhomocysteine hydrolase-like 1
chr17_-_35973192 12.361 Tubb5
tubulin, beta 5
chr11_+_62389367 12.223 Trpv2
transient receptor potential cation channel, subfamily V, member 2
chr11_-_120441643 11.938 Arhgdia
Rho GDP dissociation inhibitor (GDI) alpha
chr11_-_107050573 11.831 NM_001161329
NM_133702
 Nol11

nucleolar protein 11

chr7_-_53970378 11.749 Saa3
serum amyloid A 3
chr11_-_45758413 10.601 NM_028185
 Lsm11
U7 snRNP-specific Sm-like protein LSM11
chr2_+_170336729 10.563 NM_001110152
 Pfdn4
prefoldin 4
chr3_-_94946256 10.340 NM_027206
 Tnfaip8l2
tumor necrosis factor, alpha-induced protein 8-like 2
chr10_-_6373309 10.331 Mthfd1l
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like
chr2_+_90936845 10.226 NM_011355
 Sfpi1
SFFV proviral integration 1
chr10_-_6373388 10.170 NM_001170785
NM_001170786
NM_172308
 Mthfd1l


methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like


chr17_-_35972880 10.079 Tubb5
tubulin, beta 5
chr19_+_46379216 9.715 NM_001177369
 Nfkb2
nuclear factor of kappa light polypeptide gene enhancer in B-cells 2, p49/p100
chr3_-_129763586 9.561 Sec24b
Sec24 related gene family, member B (S. cerevisiae)
chr2_+_170336930 9.236 Pfdn4
prefoldin 4
chr19_-_6015778 8.830 NM_001110504
 Capn1
calpain 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 26 entries
Enrichment   P-value GO Accession GO Term
25.00 9.08e-03 GO:0031657 regulation of cyclin-dependent protein kinase activity involved by G1/S
25.00 9.08e-03 GO:0031659 positive regulation of cyclin-dependent protein kinase activity involved in G1/S
4.06 3.22e-02 GO:0051329 interphase of mitotic cell cycle
3.95 4.44e-02 GO:0051325 interphase
2.64 4.22e-02 GO:0051347 positive regulation of transferase activity
2.52 6.62e-03 GO:0000278 mitotic cell cycle
2.48 1.58e-03 GO:0051726 regulation of cell cycle
2.27 5.89e-03 GO:0006396 RNA processing
2.14 1.74e-02 GO:0022402 cell cycle process
1.64 3.77e-02 GO:0065009 regulation of molecular function
1.63 2.86e-04 GO:0044267 cellular protein metabolic process
1.62 2.61e-06 GO:0071840 cellular component organization or biogenesis
1.60 1.01e-04 GO:0010467 gene expression
1.58 9.05e-11 GO:0044260 cellular macromolecule metabolic process
1.57 2.67e-03 GO:0071841 cellular component organization or biogenesis at cellular level
1.55 1.96e-04 GO:0016043 cellular component organization
1.52 1.49e-03 GO:0090304 nucleic acid metabolic process
1.50 3.49e-04 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.49 3.57e-02 GO:0016070 RNA metabolic process
1.48 9.74e-12 GO:0044237 cellular metabolic process

Gene overrepresentation in compartment category:

Showing 1 to 20 of 35 entries
Enrichment   P-value GO Accession GO Term
3.73 1.65e-03 GO:0005681 spliceosomal complex
3.14 8.42e-03 GO:0005840 ribosome
2.98 3.18e-08 GO:0030529 ribonucleoprotein complex
2.77 7.17e-03 GO:0000323 lytic vacuole
2.77 7.17e-03 GO:0005764 lysosome
2.56 1.06e-02 GO:0005773 vacuole
2.48 2.04e-03 GO:0005730 nucleolus
1.99 3.21e-02 GO:0044429 mitochondrial part
1.91 3.69e-02 GO:0031967 organelle envelope
1.88 4.95e-02 GO:0031975 envelope
1.83 7.09e-07 GO:0044428 nuclear part
1.71 1.14e-04 GO:0031974 membrane-enclosed lumen
1.71 1.59e-04 GO:0070013 intracellular organelle lumen
1.71 7.32e-04 GO:0005829 cytosol
1.70 1.73e-04 GO:0043233 organelle lumen
1.65 4.37e-03 GO:0031981 nuclear lumen
1.64 2.57e-02 GO:0031090 organelle membrane
1.63 2.01e-11 GO:0044446 intracellular organelle part
1.60 7.23e-11 GO:0044422 organelle part
1.60 1.25e-02 GO:0005739 mitochondrion

Gene overrepresentation in function category:

Showing 1 to 14 of 14 entries
Enrichment   P-value GO Accession GO Term
3.74 8.62e-03 GO:0003735 structural constituent of ribosome
1.59 5.32e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.59 3.04e-02 GO:0005524 ATP binding
1.58 3.52e-02 GO:0030554 adenyl nucleotide binding
1.57 8.40e-04 GO:0000166 nucleotide binding
1.57 7.49e-03 GO:0017076 purine nucleotide binding
1.55 1.11e-02 GO:0032555 purine ribonucleotide binding
1.55 1.13e-02 GO:0032553 ribonucleotide binding
1.35 2.79e-05 GO:0005515 protein binding
1.35 3.40e-02 GO:0043169 cation binding
1.34 4.04e-02 GO:0043167 ion binding
1.34 4.37e-02 GO:0046872 metal ion binding
1.27 2.01e-02 GO:0003824 catalytic activity
1.24 2.70e-08 GO:0005488 binding