• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: E2F1..5.p2

Z-value: 6.191

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr12_+_25393083	205.825	NM_009104	Rrm2	ribonucleotide reductase M2
chr10_-_68815606	190.395	NM_007659	Cdk1	cyclin-dependent kinase 1
chr1_-_130256055	178.689	NM_008567	Mcm6	minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)
chr15_-_57966551	170.642	NM_027435	Atad2	ATPase family, AAA domain containing 2
chr8_+_77633426	170.047	NM_008566	Mcm5	minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr10_+_110182506	159.597	NM_178609	E2f7	E2F transcription factor 7
chr1_-_20810238	152.621	NM_008563	Mcm3	minichromosome maintenance deficient 3 (S. cerevisiae)
chr10_-_20880559	148.266	NM_001198914 NM_010848	Myb	myeloblastosis oncogene
chr5_-_138613028	146.050	NM_008568	Mcm7	minichromosome maintenance deficient 7 (S. cerevisiae)
chr8_+_125091889	138.459	NM_026014	Cdt1	chromatin licensing and DNA replication factor 1
chr2_+_72314235	134.555	NM_025866	Cdca7	cell division cycle associated 7
chr11_+_98769122	126.897		Cdc6	cell division cycle 6 homolog (S. cerevisiae)
chr13_-_21925343	122.491	NM_178185 NM_001177544	Hist1h2ah Hist1h2ap Hist1h2ai Hist1h2ao	histone cluster 1, H2ah histone cluster 1, H2ap histone cluster 1, H2ai histone cluster 1, H2ao
chr6_-_88848650	116.296	NM_008564	Mcm2	minichromosome maintenance deficient 2 mitotin (S. cerevisiae)
chr11_+_98769162	115.939	NM_001025779	Cdc6	cell division cycle 6 homolog (S. cerevisiae)
chr13_-_21879086	111.341	NM_178184	Hist1h2an	histone cluster 1, H2an
chr13_-_22134795	106.518	NM_178186	Hist1h2ag Hist1h2ai	histone cluster 1, H2ag histone cluster 1, H2ai
chr10_+_127669118	104.620	NM_001136082 NM_001164080 NM_001164081	Timeless	timeless homolog (Drosophila)
chr2_-_157030236	103.984	NM_001139516 NM_011249	Rbl1	retinoblastoma-like 1 (p107)
chr10_+_127669154	103.485		Timeless	timeless homolog (Drosophila)
chr2_+_118938549	102.628	NM_011234	Rad51	RAD51 homolog (S. cerevisiae)
chr4_+_135728600	102.033		E2f2	E2F transcription factor 2
chr17_+_56443766	100.991		Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1
chr17_+_56443710	100.605	NM_001111078 NM_001111080	Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1
chr19_+_39005433	96.859	NM_008234	Hells	helicase, lymphoid specific
chr10_+_4541138	95.663		Fbxo5	F-box protein 5
chr17_+_56442759	94.733	NM_001111079 NM_010931	Uhrf1	ubiquitin-like, containing PHD and RING finger domains, 1
chr10_+_4541075	93.752	NM_025995	Fbxo5	F-box protein 5
chr4_+_135728188	90.599	NM_177733	E2f2	E2F transcription factor 2
chr2_-_113688771	89.546	NM_181416	Arhgap11a	Rho GTPase activating protein 11A
chr9_+_44142772	88.706	NM_010436	H2afx	H2A histone family, member X
chr11_+_98769464	88.367	NM_011799	Cdc6	cell division cycle 6 homolog (S. cerevisiae)
chr2_-_154395469	87.360	NM_007891	E2f1	E2F transcription factor 1
chrX_-_90877453	86.459	NM_008892	Pola1	polymerase (DNA directed), alpha 1
chr13_+_21902235	85.091	NM_178185 NM_001177544	Hist1h2ah Hist1h2ap Hist1h2ai Hist1h2ao	histone cluster 1, H2ah histone cluster 1, H2ap histone cluster 1, H2ai histone cluster 1, H2ao
chr7_-_56136965	84.815		E2f8	E2F transcription factor 8
chr13_-_22127419	84.797	NM_175659	Hist1h2ah	histone cluster 1, H2ah
chr9_+_65738150	81.140		2810417H13Rik	RIKEN cDNA 2810417H13 gene
chr6_-_47544925	80.912	NM_001146689 NM_007971	Ezh2	enhancer of zeste homolog 2 (Drosophila)
chr9_-_36534167	80.264	NM_007691	Chek1	checkpoint kinase 1 homolog (S. pombe)
chr7_-_142908061	78.526	NM_001081117	Mki67	antigen identified by monoclonal antibody Ki 67
chr7_-_56136405	77.898	NM_001013368	E2f8	E2F transcription factor 8
chr9_-_20757236	77.420	NM_010066	Dnmt1	DNA methyltransferase (cytosine-5) 1
chr5_+_110715337	77.025	NM_011132	Pole	polymerase (DNA directed), epsilon
chr12_-_70329149	76.940	NM_011133	Pole2	polymerase (DNA directed), epsilon 2 (p59 subunit)
chr15_-_54921986	73.806	NM_183089	Dscc1	defective in sister chromatid cohesion 1 homolog (S. cerevisiae)
chr4_+_126234210	70.721	NM_175554	Clspn	claspin homolog (Xenopus laevis)
chr2_+_150735306	69.958	NM_001163476 NM_027014	Gins1	GINS complex subunit 1 (Psf1 homolog)
chr19_-_5964187	68.169	NM_001164057 NM_008893	Pola2	polymerase (DNA directed), alpha 2
chr5_+_89194037	68.109	NM_007832	Dck	deoxycytidine kinase
chr19_+_8797973	67.388		Snhg1	small nucleolar RNA host gene (non-protein coding) 1
chr10_-_90633803	67.223		Tmpo	thymopoietin
chr12_+_117643874	65.941	NM_133762	Ncapg2	non-SMC condensin II complex, subunit G2
chrX_-_48559008	65.924	NM_134163	Mbnl3	muscleblind-like 3 (Drosophila)
chr7_-_56136367	65.511		E2f8	E2F transcription factor 8
chr17_-_35653683	65.222	NM_001163763 NM_001163764 NM_025674	Tcf19	transcription factor 19
chr7_-_51804139	65.212	NM_011131	Pold1	polymerase (DNA directed), delta 1, catalytic subunit
chr8_-_123112974	64.179	NM_178856	Gins2	GINS complex subunit 2 (Psf2 homolog)
chr5_+_114580397	63.908	NM_001040691	Ung	uracil DNA glycosylase
chr9_+_65738129	63.840	NM_026515	2810417H13Rik	RIKEN cDNA 2810417H13 gene
chr8_-_123112925	63.645		Gins2	GINS complex subunit 2 (Psf2 homolog)
chr1_+_74552794	62.637		Rqcd1	rcd1 (required for cell differentiation) homolog 1 (S. pombe)
chr13_-_24853723	60.931	NM_020567	Gmnn	geminin
chr5_+_114581164	57.443	NM_011677	Ung	uracil DNA glycosylase
chr4_+_98590642	57.349		Usp1	ubiquitin specific peptidase 1
chr8_+_87396009	57.003	NM_001168246 NM_027954 NM_001168244	Syce2	synaptonemal complex central element protein 2
chr17_+_88374355	56.340	NM_010830	Msh6	mutS homolog 6 (E. coli)
chr4_+_114672722	55.871	NM_009185	Stil	Scl/Tal1 interrupting locus
chr2_-_154395076	55.605		E2f1	E2F transcription factor 1
chr5_+_46061125	55.245	NM_019438	Ncapg	non-SMC condensin I complex, subunit G
chr15_+_61817102	55.175		Myc	myelocytomatosis oncogene
chr8_+_125091925	54.176		Cdt1	chromatin licensing and DNA replication factor 1
chr13_+_93125099	54.091		Dhfr	dihydrofolate reductase
chr16_-_18811669	53.940	NM_001161623	Cdc45	cell division cycle 45 homolog (S. cerevisiae)
chr4_+_114672849	53.824		Stil	Scl/Tal1 interrupting locus
chr15_+_61816895	53.651	NM_001177352 NM_001177353 NM_001177354 NM_010849	Myc	myelocytomatosis oncogene
chr13_+_93125151	53.510		Dhfr	dihydrofolate reductase
chr4_+_98590565	53.223		Usp1	ubiquitin specific peptidase 1
chr15_+_55388962	52.866	NM_001168250 NM_134092	Mtbp	Mdm2, transformed 3T3 cell double minute p53 binding protein
chr9_+_109778461	51.997		Cdc25a	cell division cycle 25 homolog A (S. pombe)
chr16_-_18248701	51.546	NM_011239	Ranbp1	RAN binding protein 1
chr9_+_65738168	48.951		2810417H13Rik	RIKEN cDNA 2810417H13 gene
chr8_+_13338741	48.648		Tfdp1	transcription factor Dp 1
chr1_-_193399412	48.524	NM_029766	Dtl	denticleless homolog (Drosophila)
chr4_+_11118855	48.259	NM_009830	Ccne2	cyclin E2
chr3_+_95733480	47.719		Anp32e	acidic (leucine-rich) nuclear phosphoprotein 32 family, member E
chr13_-_30077931	46.546	NM_010093	E2f3	E2F transcription factor 3
chr1_+_74552600	46.528	NM_021383	Rqcd1	rcd1 (required for cell differentiation) homolog 1 (S. pombe)
chr5_+_89194155	46.211		Dck	deoxycytidine kinase
chr18_+_56867378	45.653	NM_010721	Lmnb1	lamin B1
chr11_+_79902901	45.556	NM_001029856	Atad5	ATPase family, AAA domain containing 5
chr14_-_21208006	45.389	NM_134081	Dnajc9	DnaJ (Hsp40) homolog, subfamily C, member 9
chr13_-_101545800	44.592	NM_021886	Cenph	centromere protein H
chr11_-_117687109	44.337	NM_009387	Tk1	thymidine kinase 1
chr9_+_64129387	44.200	NM_025372	Tipin	timeless interacting protein
chrX_-_7651846	44.057	NM_011514	Suv39h1	suppressor of variegation 3-9 homolog 1 (Drosophila)
chr6_-_125141525	43.979	NM_146171	Ncapd2	non-SMC condensin I complex, subunit D2
chr4_+_134066913	43.733	NM_001081099	2610002D18Rik	RIKEN cDNA 2610002D18 gene
chr2_+_121781736	43.700		Ctdspl2	CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr11_+_79806552	43.624	NM_001163018 NM_199196	Suz12	suppressor of zeste 12 homolog (Drosophila)
chr5_-_152453753	43.445	NM_027009	Rfc3	replication factor C (activator 1) 3
chr1_+_133807034	43.401	NM_001145804 NM_175294	Nucks1	nuclear casein kinase and cyclin-dependent kinase substrate 1
chr15_-_9070066	43.337	NM_013787 NM_145468	Skp2	S-phase kinase-associated protein 2 (p45)
chr3_+_137528537	43.053		H2afz	H2A histone family, member Z
chr17_+_23863280	42.921	NM_023058	Pkmyt1	protein kinase, membrane associated tyrosine/threonine 1
chr13_+_23666249	42.807	NM_178188	Hist1h2ad Hist1h2ai	histone cluster 1, H2ad histone cluster 1, H2ai
chr2_+_162880370	42.650	NM_008652	Mybl2	myeloblastosis oncogene-like 2
chr6_-_148894953	42.532	NM_019643	Fam60a	family with sequence similarity 60, member A
chr12_-_12948513	42.391	NM_008709	Mycn	v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chrX_-_7651372	42.134		Suv39h1	suppressor of variegation 3-9 homolog 1 (Drosophila)
chr16_-_18248659	41.809		Ranbp1	RAN binding protein 1
chrX_-_7651692	41.539		Suv39h1	suppressor of variegation 3-9 homolog 1 (Drosophila)
chr4_+_98590457	41.151	NM_146144	Usp1	ubiquitin specific peptidase 1
chr10_-_90633199	40.282		Tmpo	thymopoietin
chr7_-_107269928	39.981	NM_133692	Pold3	polymerase (DNA-directed), delta 3, accessory subunit
chr13_-_55431027	39.855	NM_016662	Mxd3	Max dimerization protein 3
chr9_+_109778051	39.790	NM_007658	Cdc25a	cell division cycle 25 homolog A (S. pombe)
chr13_+_23625779	38.800	NM_175661	Hist1h2af	histone cluster 1, H2af
chr4_-_148511650	38.168	NM_027263	Apitd1	apoptosis-inducing, TAF9-like domain 1
chr15_-_97923632	37.293	NM_144851	Senp1	SUMO1/sentrin specific peptidase 1
chr1_-_183772442	37.010	NM_133815	Lbr	lamin B receptor
chr11_-_87217940	36.837	NM_053269	Rad51c	RAD51 homolog c (S. cerevisiae)
chr17_-_23810808	36.241		Thoc6	THO complex 6 homolog (Drosophila)
chr1_-_193399352	35.159		Dtl	denticleless homolog (Drosophila)
chr2_+_84877598	34.958	NM_001136081	Ssrp1	structure specific recognition protein 1
chr4_+_132324212	34.888	NM_011284	Rpa2	replication protein A2
chr8_+_98157458	34.795	NM_030198	Gins3	GINS complex subunit 3 (Psf3 homolog)
chr1_+_88423294	34.520		Ptma	prothymosin alpha
chr4_+_135412028	34.129		Srsf10	serine/arginine-rich splicing factor 10
chr1_+_88423310	33.460	NM_008972	Ptma	prothymosin alpha
chr7_-_135883942	33.413	NM_145955	Mcmbp	MCM (minichromosome maintenance deficient) binding protein
chr4_+_135412062	33.223		Srsf10	serine/arginine-rich splicing factor 10
chr3_+_40603872	32.899	NM_011495	Plk4	polo-like kinase 4 (Drosophila)
chr2_+_84877325	32.575	NM_182990	Ssrp1	structure specific recognition protein 1
chr3_-_88214230	32.468	NM_025928	Pmf1	polyamine-modulated factor 1
chr16_-_22265901	32.378	NM_009186	Tra2b	transformer 2 beta homolog (Drosophila)
chr2_+_84877428	31.777		Ssrp1	structure specific recognition protein 1
chr4_+_135411923	31.767	NM_001080387 NM_010178	Srsf10	serine/arginine-rich splicing factor 10
chrX_+_148450970	31.677	NM_019710	Smc1a	structural maintenance of chromosomes 1A
chr17_+_88840048	31.639	NM_180974	Foxn2	forkhead box N2
chr3_-_88214215	31.292		Pmf1	polyamine-modulated factor 1
chr9_+_100544186	31.277		Stag1	stromal antigen 1
chr16_-_15637390	30.928	NM_008565	Mcm4	minichromosome maintenance deficient 4 homolog (S. cerevisiae)
chr8_-_97437166	30.769		Ccdc102a	coiled-coil domain containing 102A
chr4_+_32702401	30.623	NM_001122978 NM_011997	Casp8ap2	caspase 8 associated protein 2
chr4_+_107040647	30.364		Tmem48	transmembrane protein 48
chr14_-_48037874	30.214		Dlgap5	discs, large (Drosophila) homolog-associated protein 5
chr4_+_107040634	30.152		Tmem48	transmembrane protein 48
chr16_-_4559511	29.939	NM_031182	Tcfap4	transcription factor AP4
chr14_-_48037815	29.787		Dlgap5	discs, large (Drosophila) homolog-associated protein 5
chr3_+_41367304	29.779	NM_172303	Phf17	PHD finger protein 17
chr8_+_98157405	29.704		Gins3	GINS complex subunit 3 (Psf3 homolog)
chr4_+_108252056	29.458	NM_011015	Orc1	origin recognition complex, subunit 1
chr9_+_103207488	29.355	NM_176979	Topbp1	topoisomerase (DNA) II binding protein 1
chr7_+_73254341	29.326	NM_001081163	Chsy1	chondroitin sulfate synthase 1
chr19_+_46150521	29.114		Nolc1	nucleolar and coiled-body phosphoprotein 1
chr8_-_81032730	29.110		Rbmxrt	RNA binding motif protein, X chromosome retrogene
chr2_+_53051140	29.086		Arl6ip6	ADP-ribosylation factor-like 6 interacting protein 6
chrX_+_48194531	28.756		2610018G03Rik	RIKEN cDNA 2610018G03 gene
chrX_+_148451021	28.612		Smc1a	structural maintenance of chromosomes 1A
chr15_+_8059306	28.589	NM_133227	Nup155	nucleoporin 155
chrX_+_48194578	28.414	NM_133729	2610018G03Rik	RIKEN cDNA 2610018G03 gene
chr7_-_134169581	28.207		Maz	MYC-associated zinc finger protein (purine-binding transcription factor)
chr3_+_97817440	28.020	NM_010928	Notch2	Notch gene homolog 2 (Drosophila)
chr6_+_113481672	27.788	NM_001033244	Fancd2	Fanconi anemia, complementation group D2
chr8_-_81032819	27.667	NM_009033	Rbmxrt	RNA binding motif protein, X chromosome retrogene
chrX_-_70704286	27.525	NM_028633 NM_207104	Haus7	HAUS augmin-like complex, subunit 7
chr8_+_77517536	27.444	NM_178017	Hmgxb4	HMG box domain containing 4
chrX_+_39503858	27.407	NM_021465	Stag2	stromal antigen 2
chr2_+_53051093	27.372	NM_022989	Arl6ip6	ADP-ribosylation factor-like 6 interacting protein 6
chr7_+_52071622	27.352	NM_001171024 NM_053074	Nup62-il4i1 Nup62	Nup62-Il4i1 protein nucleoporin 62
chr3_+_41367672	27.171	NM_001130185	Phf17	PHD finger protein 17
chr4_+_11118500	26.720	NM_001037134	Ccne2	cyclin E2
chr14_-_31832274	26.676	NM_153547	Gnl3	guanine nucleotide binding protein-like 3 (nucleolar)
chr1_-_169215189	26.470		Uck2	uridine-cytidine kinase 2
chr5_+_108494692	26.251	NM_013827	Mtf2	metal response element binding transcription factor 2
chr8_+_87225390	26.229		Lyl1	lymphoblastomic leukemia 1
chr2_-_163575826	26.216	NM_007398	Ada	adenosine deaminase
chr4_-_132399023	26.074	NM_146154	Ppp1r8	protein phosphatase 1, regulatory (inhibitor) subunit 8
chr15_-_81702298	25.792	NM_026737	Phf5a	PHD finger protein 5A
chr7_+_52071438	25.373		Nup62	nucleoporin 62
chr14_-_48038081	24.795	NM_001145949 NM_144553	Dlgap5	discs, large (Drosophila) homolog-associated protein 5
chr5_+_111268995	24.611		Chek2	CHK2 checkpoint homolog (S. pombe)
chr3_+_116297899	24.559	NM_028349	Sass6	spindle assembly 6 homolog (C. elegans)
chr1_+_159342482	24.289		2810025M15Rik	RIKEN cDNA 2810025M15 gene
chr8_-_81032795	24.244		Rbmxrt	RNA binding motif protein, X chromosome retrogene
chr3_-_83959616	24.052	NM_029797	Mnd1	meiotic nuclear divisions 1 homolog (S. cerevisiae)
chr11_-_6344354	23.844		H2afv	H2A histone family, member V
chr5_+_111269020	23.811	NM_016681	Chek2	CHK2 checkpoint homolog (S. pombe)
chr4_+_135412061	23.568		Srsf10	serine/arginine-rich splicing factor 10
chr2_+_75670242	23.558		Agps	alkylglycerone phosphate synthase
chr2_+_31526229	23.385	NM_144886	Exosc2	exosome component 2
chr2_-_132078946	23.267		Pcna	proliferating cell nuclear antigen
chr4_+_134024234	23.141	NM_019641	Stmn1	stathmin 1
chr10_+_36694535	23.090		Hdac2	histone deacetylase 2
chr17_+_28828286	22.907	NM_001168508 NM_001168514 NM_011951	Mapk14	mitogen-activated protein kinase 14
chr1_-_169215216	22.793	NM_030724	Uck2	uridine-cytidine kinase 2
chr19_+_53674862	22.638	NM_007790	Smc3	structural maintenace of chromosomes 3
chr2_-_132078887	22.620	NM_011045	Pcna	proliferating cell nuclear antigen
chr5_-_65726802	22.599	NM_011258	Rfc1	replication factor C (activator 1) 1

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
2.66	4.27e-74	GO:0090304	nucleic acid metabolic process
2.08	8.94e-68	GO:0044260	cellular macromolecule metabolic process
2.41	1.95e-67	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.24	1.81e-60	GO:0034641	cellular nitrogen compound metabolic process
2.21	1.20e-59	GO:0006807	nitrogen compound metabolic process
1.93	1.54e-59	GO:0043170	macromolecule metabolic process
1.72	1.22e-49	GO:0044237	cellular metabolic process
2.44	7.13e-48	GO:0016070	RNA metabolic process
1.69	5.27e-46	GO:0044238	primary metabolic process
2.31	7.92e-45	GO:0010467	gene expression
2.30	7.19e-41	GO:0009059	macromolecule biosynthetic process
2.30	1.24e-40	GO:0034645	cellular macromolecule biosynthetic process
1.56	4.60e-38	GO:0008152	metabolic process
4.18	1.38e-34	GO:0006259	DNA metabolic process
2.14	2.15e-33	GO:2000112	regulation of cellular macromolecule biosynthetic process
2.11	1.01e-32	GO:0010556	regulation of macromolecule biosynthetic process
1.99	1.26e-32	GO:0044249	cellular biosynthetic process
1.95	1.04e-31	GO:0009058	biosynthetic process
2.05	2.44e-31	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.03	6.33e-31	GO:0051171	regulation of nitrogen compound metabolic process
2.01	1.35e-29	GO:0031326	regulation of cellular biosynthetic process
2.34	1.43e-29	GO:0032774	RNA biosynthetic process
6.82	2.13e-29	GO:0006260	DNA replication
2.34	3.20e-29	GO:0006351	transcription, DNA-dependent
1.99	5.06e-29	GO:0009889	regulation of biosynthetic process
2.10	6.66e-29	GO:0051252	regulation of RNA metabolic process
2.10	3.28e-28	GO:0006355	regulation of transcription, DNA-dependent
3.10	3.52e-28	GO:0007049	cell cycle
1.85	5.20e-28	GO:0060255	regulation of macromolecule metabolic process
1.99	2.02e-27	GO:0010468	regulation of gene expression
1.81	9.74e-27	GO:0031323	regulation of cellular metabolic process
1.81	1.30e-26	GO:0080090	regulation of primary metabolic process
1.71	2.49e-24	GO:0019222	regulation of metabolic process
4.36	2.03e-20	GO:0008380	RNA splicing
3.26	2.57e-20	GO:0006396	RNA processing
3.61	1.43e-19	GO:0006974	response to DNA damage stimulus
3.46	5.63e-19	GO:0022403	cell cycle phase
3.73	2.19e-18	GO:0016071	mRNA metabolic process
4.02	4.43e-18	GO:0006281	DNA repair
3.11	9.85e-17	GO:0051276	chromosome organization
2.89	5.31e-16	GO:0022402	cell cycle process
1.22	2.00e-15	GO:0009987	cellular process
3.75	6.11e-15	GO:0006397	mRNA processing
3.17	3.55e-13	GO:0000278	mitotic cell cycle
2.53	3.59e-12	GO:0033554	cellular response to stress
3.22	4.76e-12	GO:0000279	M phase
3.20	1.06e-11	GO:0051301	cell division
1.94	1.75e-11	GO:0006996	organelle organization
3.02	3.08e-11	GO:0006325	chromatin organization
1.70	1.14e-10	GO:0071841	cellular component organization or biogenesis at cellular level
3.12	1.72e-10	GO:0016568	chromatin modification
1.95	2.97e-10	GO:0010604	positive regulation of macromolecule metabolic process
2.17	4.57e-10	GO:0010557	positive regulation of macromolecule biosynthetic process
2.34	5.97e-10	GO:0051172	negative regulation of nitrogen compound metabolic process
2.26	5.97e-10	GO:0051254	positive regulation of RNA metabolic process
1.56	6.40e-10	GO:0071840	cellular component organization or biogenesis
2.35	6.97e-10	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.20	8.84e-10	GO:0010628	positive regulation of gene expression
2.16	1.17e-09	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.25	1.69e-09	GO:0045893	positive regulation of transcription, DNA-dependent
2.13	2.15e-09	GO:0051173	positive regulation of nitrogen compound metabolic process
2.23	4.07e-09	GO:0031327	negative regulation of cellular biosynthetic process
1.88	5.37e-09	GO:0031325	positive regulation of cellular metabolic process
2.21	5.85e-09	GO:0009890	negative regulation of biosynthetic process
2.04	7.44e-09	GO:0010605	negative regulation of macromolecule metabolic process
1.66	8.59e-09	GO:0071842	cellular component organization at cellular level
2.26	9.38e-09	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
2.23	1.16e-08	GO:0010558	negative regulation of macromolecule biosynthetic process
1.55	1.20e-08	GO:0016043	cellular component organization
2.04	1.49e-08	GO:0031328	positive regulation of cellular biosynthetic process
1.97	1.58e-08	GO:0009892	negative regulation of metabolic process
2.02	1.82e-08	GO:0006357	regulation of transcription from RNA polymerase II promoter
2.02	2.07e-08	GO:0009891	positive regulation of biosynthetic process
3.59	2.20e-08	GO:0016569	covalent chromatin modification
7.21	2.20e-08	GO:0006261	DNA-dependent DNA replication
1.82	2.24e-08	GO:0009893	positive regulation of metabolic process
1.64	2.60e-08	GO:0048523	negative regulation of cellular process
1.57	4.73e-08	GO:0048522	positive regulation of cellular process
16.57	8.61e-08	GO:0006270	DNA-dependent DNA replication initiation
1.53	9.74e-08	GO:0048518	positive regulation of biological process
1.97	1.53e-07	GO:0031324	negative regulation of cellular metabolic process
4.60	1.95e-07	GO:0051329	interphase of mitotic cell cycle
3.21	2.14e-07	GO:0000087	M phase of mitotic cell cycle
3.45	2.53e-07	GO:0016570	histone modification
2.46	3.39e-07	GO:0051726	regulation of cell cycle
4.47	3.88e-07	GO:0051325	interphase
3.20	4.13e-07	GO:0000280	nuclear division
3.20	4.13e-07	GO:0007067	mitosis
15.07	4.51e-07	GO:0071897	DNA biosynthetic process
1.55	9.33e-07	GO:0048519	negative regulation of biological process
3.07	1.37e-06	GO:0048285	organelle fission
2.18	1.57e-06	GO:0051253	negative regulation of RNA metabolic process
2.11	2.26e-06	GO:0010629	negative regulation of gene expression
1.44	3.33e-06	GO:0032502	developmental process
2.19	5.30e-06	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
4.72	9.25e-06	GO:0006473	protein acetylation
1.62	1.08e-05	GO:0043412	macromolecule modification
2.12	1.18e-05	GO:0045892	negative regulation of transcription, DNA-dependent
11.84	1.41e-05	GO:0090329	regulation of DNA-dependent DNA replication
4.07	1.45e-05	GO:0007059	chromosome segregation
1.43	2.72e-05	GO:0007275	multicellular organismal development
9.69	2.87e-05	GO:0006297	nucleotide-excision repair, DNA gap filling
1.61	2.92e-05	GO:0006464	protein modification process
4.20	3.61e-05	GO:0043543	protein acylation
3.89	3.74e-05	GO:0071103	DNA conformation change
4.01	4.13e-05	GO:0018205	peptidyl-lysine modification
2.90	4.82e-05	GO:0010564	regulation of cell cycle process
12.28	6.83e-05	GO:2000104	negative regulation of DNA-dependent DNA replication
4.60	8.45e-05	GO:0018394	peptidyl-lysine acetylation
1.44	8.88e-05	GO:0048856	anatomical structure development
1.48	1.89e-04	GO:0044267	cellular protein metabolic process
1.55	2.05e-04	GO:0048513	organ development
4.54	2.54e-04	GO:0016573	histone acetylation
3.21	2.70e-04	GO:0051052	regulation of DNA metabolic process
1.80	2.95e-04	GO:0042127	regulation of cell proliferation
5.84	3.20e-04	GO:0043966	histone H3 acetylation
6.31	3.67e-04	GO:0008156	negative regulation of DNA replication
4.41	3.98e-04	GO:0006475	internal protein amino acid acetylation
4.41	3.98e-04	GO:0018393	internal peptidyl-lysine acetylation
3.68	4.11e-04	GO:0051321	meiotic cell cycle
4.93	4.31e-04	GO:0006289	nucleotide-excision repair
4.09	5.86e-04	GO:0006275	regulation of DNA replication
1.72	8.56e-04	GO:0044085	cellular component biogenesis
8.29	8.81e-04	GO:0007062	sister chromatid cohesion
2.44	1.08e-03	GO:0018193	peptidyl-amino acid modification
4.87	1.33e-03	GO:0051053	negative regulation of DNA metabolic process
3.54	1.55e-03	GO:0007126	meiosis
3.54	1.55e-03	GO:0051327	M phase of meiotic cell cycle
1.42	1.61e-03	GO:0048731	system development
6.82	1.76e-03	GO:0033261	regulation of S phase
2.75	3.94e-03	GO:0007346	regulation of mitotic cell cycle
1.74	6.35e-03	GO:0009790	embryo development
3.83	6.92e-03	GO:0050657	nucleic acid transport
3.83	6.92e-03	GO:0050658	RNA transport
3.83	6.92e-03	GO:0051236	establishment of RNA localization
4.00	7.75e-03	GO:0006401	RNA catabolic process
4.52	8.33e-03	GO:0000082	G1/S transition of mitotic cell cycle
3.60	8.36e-03	GO:0040029	regulation of gene expression, epigenetic
11.05	1.00e-02	GO:0000084	S phase of mitotic cell cycle
11.05	1.00e-02	GO:0006268	DNA unwinding involved in replication
1.83	1.05e-02	GO:0043933	macromolecular complex subunit organization
3.68	1.17e-02	GO:0006403	RNA localization
7.37	1.18e-02	GO:0032392	DNA geometric change
2.56	1.50e-02	GO:0071843	cellular component biogenesis at cellular level
2.60	1.68e-02	GO:0022613	ribonucleoprotein complex biogenesis
18.42	1.97e-02	GO:0019985	translesion synthesis
13.15	2.04e-02	GO:0000731	DNA synthesis involved in DNA repair
10.05	2.10e-02	GO:0051320	S phase
3.22	2.27e-02	GO:0006310	DNA recombination
1.82	2.93e-02	GO:0065003	macromolecular complex assembly
1.98	2.98e-02	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
4.71	3.02e-02	GO:0000956	nuclear-transcribed mRNA catabolic process
1.51	3.17e-02	GO:0009653	anatomical structure morphogenesis
3.79	3.18e-02	GO:0000377	RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
3.79	3.18e-02	GO:0000398	nuclear mRNA splicing, via spliceosome
1.95	3.36e-02	GO:0007417	central nervous system development
3.74	3.79e-02	GO:0000375	RNA splicing, via transesterification reactions
3.74	3.79e-02	GO:0051028	mRNA transport
1.59	3.85e-02	GO:0050793	regulation of developmental process
4.17	4.73e-02	GO:0006402	mRNA catabolic process

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
2.28	1.12e-105	GO:0005634	nucleus
1.69	6.69e-73	GO:0043227	membrane-bounded organelle
1.69	7.52e-73	GO:0043231	intracellular membrane-bounded organelle
1.61	8.75e-72	GO:0043226	organelle
1.61	1.90e-71	GO:0043229	intracellular organelle
3.04	2.86e-66	GO:0044428	nuclear part
1.49	4.71e-64	GO:0044424	intracellular part
1.47	2.56e-62	GO:0005622	intracellular
3.05	2.89e-53	GO:0031981	nuclear lumen
3.41	1.25e-47	GO:0005654	nucleoplasm
2.75	3.80e-47	GO:0070013	intracellular organelle lumen
2.74	5.35e-47	GO:0043233	organelle lumen
2.71	1.73e-46	GO:0031974	membrane-enclosed lumen
1.90	3.94e-41	GO:0044446	intracellular organelle part
1.88	8.18e-40	GO:0044422	organelle part
3.20	2.77e-26	GO:0044451	nucleoplasm part
3.69	6.61e-25	GO:0005694	chromosome
1.77	4.54e-23	GO:0032991	macromolecular complex
3.59	2.02e-21	GO:0044427	chromosomal part
1.85	6.19e-19	GO:0043228	non-membrane-bounded organelle
1.85	6.19e-19	GO:0043232	intracellular non-membrane-bounded organelle
1.64	7.69e-13	GO:0043234	protein complex
3.86	2.38e-12	GO:0000785	chromatin
2.75	5.94e-12	GO:0030529	ribonucleoprotein complex
3.83	6.67e-12	GO:0000228	nuclear chromosome
1.13	7.46e-12	GO:0005623	cell
1.13	7.46e-12	GO:0044464	cell part
3.97	3.17e-11	GO:0044454	nuclear chromosome part
4.26	1.54e-09	GO:0005681	spliceosomal complex
3.98	2.19e-08	GO:0016604	nuclear body
2.62	6.94e-08	GO:0005730	nucleolus
4.37	5.29e-07	GO:0000790	nuclear chromatin
7.48	1.55e-06	GO:0005657	replication fork
4.60	2.31e-06	GO:0071013	catalytic step 2 spliceosome
3.55	5.18e-06	GO:0000775	chromosome, centromeric region
3.87	2.64e-05	GO:0000793	condensed chromosome
2.48	2.79e-05	GO:0005667	transcription factor complex
4.68	5.91e-05	GO:0000792	heterochromatin
4.60	7.48e-05	GO:0000123	histone acetyltransferase complex
18.42	1.66e-04	GO:0042555	MCM complex
2.77	3.28e-04	GO:0005635	nuclear envelope
4.37	8.43e-04	GO:0034708	methyltransferase complex
4.37	8.43e-04	GO:0035097	histone methyltransferase complex
11.05	1.56e-03	GO:0005652	nuclear lamina
3.64	2.16e-03	GO:0016585	chromatin remodeling complex
3.99	5.58e-03	GO:0034399	nuclear periphery
1.15	8.50e-03	GO:0005737	cytoplasm
3.33	1.27e-02	GO:0031965	nuclear membrane
2.93	1.30e-02	GO:0005819	spindle
6.79	1.37e-02	GO:0031519	PcG protein complex
10.23	1.74e-02	GO:0035098	ESC/E(Z) complex
4.39	2.26e-02	GO:0016605	PML body
6.91	4.48e-02	GO:0043596	nuclear replication fork

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
2.46	7.52e-57	GO:0003676	nucleic acid binding
2.58	9.99e-42	GO:0003677	DNA binding
1.35	2.58e-31	GO:0005488	binding
2.54	1.50e-15	GO:0001071	nucleic acid binding transcription factor activity
2.54	1.50e-15	GO:0003700	sequence-specific DNA binding transcription factor activity
2.29	1.50e-13	GO:0030528	transcription regulator activity
1.75	7.66e-13	GO:0000166	nucleotide binding
2.39	7.96e-12	GO:0003723	RNA binding
3.79	5.17e-11	GO:0043566	structure-specific DNA binding
3.10	1.41e-10	GO:0008134	transcription factor binding
1.36	4.51e-10	GO:0005515	protein binding
3.63	4.74e-10	GO:0003682	chromatin binding
2.27	4.67e-09	GO:0043565	sequence-specific DNA binding
1.78	6.17e-08	GO:0008270	zinc ion binding
16.11	5.26e-06	GO:0070888	E-box binding
7.62	6.85e-06	GO:0003887	DNA-directed DNA polymerase activity
1.60	1.00e-05	GO:0046914	transition metal ion binding
6.91	2.56e-05	GO:0034061	DNA polymerase activity
3.27	7.60e-05	GO:0003690	double-stranded DNA binding
2.41	8.16e-05	GO:0016564	transcription repressor activity
2.72	1.94e-04	GO:0000975	regulatory region DNA binding
2.72	1.94e-04	GO:0001067	regulatory region nucleic acid binding
2.72	1.94e-04	GO:0044212	transcription regulatory region DNA binding
1.58	2.13e-04	GO:0005524	ATP binding
1.57	2.32e-04	GO:0030554	adenyl nucleotide binding
2.58	2.94e-04	GO:0003712	transcription cofactor activity
1.56	3.09e-04	GO:0032559	adenyl ribonucleotide binding
2.56	3.25e-04	GO:0000989	transcription factor binding transcription factor activity
2.29	3.39e-04	GO:0016563	transcription activator activity
1.51	3.40e-04	GO:0035639	purine ribonucleoside triphosphate binding
2.53	4.33e-04	GO:0000988	protein binding transcription factor activity
1.49	4.78e-04	GO:0017076	purine nucleotide binding
1.49	6.24e-04	GO:0032555	purine ribonucleotide binding
1.49	6.45e-04	GO:0032553	ribonucleotide binding
4.79	9.07e-04	GO:0003697	single-stranded DNA binding
3.56	1.12e-03	GO:0003714	transcription corepressor activity
1.48	1.17e-03	GO:0016740	transferase activity
1.61	9.65e-03	GO:0016772	transferase activity, transferring phosphorus-containing groups
2.43	1.27e-02	GO:0010843	promoter binding
1.28	1.50e-02	GO:0046872	metal ion binding
3.44	2.25e-02	GO:0042393	histone binding
1.27	2.29e-02	GO:0043169	cation binding
2.98	2.45e-02	GO:0016779	nucleotidyltransferase activity
1.27	2.89e-02	GO:0043167	ion binding
1.76	4.81e-02	GO:0019904	protein domain specific binding