Motif ID: ELF1,2,4.p2

Z-value: 3.557


Transcription factors associated with ELF1,2,4.p2:

Gene SymbolEntrez IDGene Name
Elf1 13709 E74-like factor 1
Elf2 69257 E74-like factor 2
Elf4 56501 E74-like factor 4 (ets domain transcription factor)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Elf1chr14_+_798809520.802.8e-41Click!
Elf2chr3_-_511299080.721.6e-30Click!
Elf4chrX_-_458163080.485.5e-12Click!


Activity profile for motif ELF1,2,4.p2.

activity profile for motif ELF1,2,4.p2


Sorted Z-values histogram for motif ELF1,2,4.p2

Sorted Z-values for motif ELF1,2,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ELF1,2,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_73367455 41.375 NM_153138
 Wipf1
WAS/WASL interacting protein family, member 1
chr8_+_72332573 37.251 NM_198101
 Gmip
Gem-interacting protein
chr9_+_107885355 35.134 NM_177090
 Cdh29
Uba7
cadherin-like 29
ubiquitin-like modifier activating enzyme 7
chr7_+_50692442 33.118 NM_024253
 Nkg7
natural killer cell group 7 sequence
chr4_-_123427465 31.214 NM_023423
 Akirin1
akirin 1
chrX_-_90877453 29.872 NM_008892
 Pola1
polymerase (DNA directed), alpha 1
chr16_+_48994292 29.248 NM_172616
 C330027C09Rik
RIKEN cDNA C330027C09 gene
chr11_+_117061031 29.133 Sept9
septin 9
chr16_-_19983049 28.924 NM_183390
 Klhl6
kelch-like 6 (Drosophila)
chr6_-_87788752 28.750 NM_133934
 Isy1
ISY1 splicing factor homolog (S. cerevisiae)
chr6_+_117856781 28.570 NM_001166430
NM_001166431
NM_133834
 Hnrnpf


heterogeneous nuclear ribonucleoprotein F


chr9_-_32348863 28.493 NM_008026
 Fli1
Friend leukemia integration 1
chr2_-_25052245 28.309 NM_146115
 A830007P12Rik
RIKEN cDNA A830007P12 gene
chr15_+_78730168 27.759 NM_009164
 Sh3bp1
SH3-domain binding protein 1
chr6_+_119429620 27.539 NM_133940
 Fbxl14
F-box and leucine-rich repeat protein 14
chr12_-_32893074 27.460 NM_001146201
NM_020272
NM_001146200
 Pik3cg


phosphoinositide-3-kinase, catalytic, gamma polypeptide


chr1_+_89110855 27.412 Eif4e2
eukaryotic translation initiation factor 4E member 2
chr7_-_133512962 27.046 NM_010689
 Lat
linker for activation of T cells
chr8_+_86479405 26.879 NM_024184
 Asf1b
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr6_-_87788729 26.727 Isy1
ISY1 splicing factor homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 249 entries
Enrichment   P-value GO Accession GO Term
3.08 4.21e-02 GO:0045577 regulation of B cell differentiation
2.82 3.90e-13 GO:0006414 translational elongation
2.68 7.47e-04 GO:0043966 histone H3 acetylation
2.60 1.94e-10 GO:0006364 rRNA processing
2.58 1.01e-14 GO:0042254 ribosome biogenesis
2.57 2.02e-02 GO:0000819 sister chromatid segregation
2.53 1.82e-04 GO:0050871 positive regulation of B cell activation
2.52 1.23e-09 GO:0016072 rRNA metabolic process
2.52 3.41e-06 GO:0000377 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile
2.52 3.41e-06 GO:0000398 nuclear mRNA splicing, via spliceosome
2.49 1.38e-19 GO:0022613 ribonucleoprotein complex biogenesis
2.49 6.12e-06 GO:0000375 RNA splicing, via transesterification reactions
2.49 6.12e-06 GO:0016573 histone acetylation
2.46 2.96e-29 GO:0006412 translation
2.42 1.87e-05 GO:0006475 internal protein amino acid acetylation
2.42 1.87e-05 GO:0018393 internal peptidyl-lysine acetylation
2.40 6.14e-26 GO:0008380 RNA splicing
2.40 1.93e-18 GO:0071843 cellular component biogenesis at cellular level
2.40 2.15e-02 GO:0030183 B cell differentiation
2.40 2.15e-02 GO:0045582 positive regulation of T cell differentiation

Gene overrepresentation in compartment category:

Showing 1 to 20 of 68 entries
Enrichment   P-value GO Accession GO Term
2.97 1.03e-14 GO:0071013 catalytic step 2 spliceosome
2.93 3.39e-03 GO:0005689 U12-type spliceosomal complex
2.82 6.21e-22 GO:0005681 spliceosomal complex
2.80 2.92e-02 GO:0015030 Cajal body
2.72 7.37e-04 GO:0022627 cytosolic small ribosomal subunit
2.67 1.09e-02 GO:0000781 chromosome, telomeric region
2.61 5.48e-03 GO:0005657 replication fork
2.54 9.19e-07 GO:0000123 histone acetyltransferase complex
2.53 1.81e-04 GO:0022626 cytosolic ribosome
2.51 1.28e-04 GO:0016363 nuclear matrix
2.40 2.90e-03 GO:0005643 nuclear pore
2.39 9.22e-05 GO:0034708 methyltransferase complex
2.39 9.22e-05 GO:0035097 histone methyltransferase complex
2.39 3.12e-02 GO:0015934 large ribosomal subunit
2.37 4.45e-05 GO:0000792 heterochromatin
2.33 1.61e-03 GO:0015935 small ribosomal subunit
2.27 5.96e-04 GO:0034399 nuclear periphery
2.23 2.68e-37 GO:0030529 ribonucleoprotein complex
2.14 9.17e-11 GO:0005840 ribosome
2.08 3.31e-02 GO:0016607 nuclear speck

Gene overrepresentation in function category:

Showing 1 to 20 of 68 entries
Enrichment   P-value GO Accession GO Term
2.83 3.37e-03 GO:0003678 DNA helicase activity
2.71 2.34e-10 GO:0008026 ATP-dependent helicase activity
2.71 2.34e-10 GO:0070035 purine NTP-dependent helicase activity
2.41 4.88e-04 GO:0004527 exonuclease activity
2.39 3.58e-03 GO:0004812 aminoacyl-tRNA ligase activity
2.39 3.58e-03 GO:0016875 ligase activity, forming carbon-oxygen bonds
2.39 3.58e-03 GO:0016876 ligase activity, forming aminoacyl-tRNA and related compounds
2.32 3.36e-07 GO:0008135 translation factor activity, nucleic acid binding
2.31 6.55e-04 GO:0003743 translation initiation factor activity
2.29 4.24e-09 GO:0003735 structural constituent of ribosome
2.23 2.78e-09 GO:0004386 helicase activity
2.06 4.12e-42 GO:0003723 RNA binding
2.05 5.23e-04 GO:0047485 protein N-terminus binding
2.00 2.38e-06 GO:0004518 nuclease activity
1.97 7.96e-07 GO:0008168 methyltransferase activity
1.95 1.10e-06 GO:0016741 transferase activity, transferring one-carbon groups
1.92 1.82e-02 GO:0004519 endonuclease activity
1.84 2.19e-03 GO:0016853 isomerase activity
1.84 9.98e-03 GO:0016779 nucleotidyltransferase activity
1.75 1.06e-08 GO:0008134 transcription factor binding