Motif ID: EP300.p2

Z-value: 1.066


Transcription factors associated with EP300.p2:

Gene SymbolEntrez IDGene Name
Ep300 328572 E1A binding protein p300

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ep300chr15_+_81416643-0.424.6e-09Click!


Activity profile for motif EP300.p2.

activity profile for motif EP300.p2


Sorted Z-values histogram for motif EP300.p2

Sorted Z-values for motif EP300.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EP300.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_121426422 15.275 NM_010171
F3
coagulation factor III
chr2_+_32780021 8.437


chr7_+_69493148 8.359 NM_010882
Ndn
necdin
chr9_-_20781133 5.907 S1pr2
sphingosine-1-phosphate receptor 2
chr10_-_58684199 5.880 Sept10
septin 10
chr9_-_20781206 5.570 NM_010333
S1pr2
sphingosine-1-phosphate receptor 2
chr10_+_58684631 5.245 NM_172939
Ankrd57
ankyrin repeat domain 57
chr1_-_82287990 5.083 NM_010570
Irs1
insulin receptor substrate 1
chr1_-_79855177 5.061 Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chrX_+_33652066 5.009 NM_133990
Il13ra1
interleukin 13 receptor, alpha 1
chr2_+_164312023 4.967 Dbndd2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr4_+_104829963 4.784 Ppap2b
phosphatidic acid phosphatase type 2B
chr7_-_149838254 4.459 Igf2
insulin-like growth factor 2
chr12_-_102988596 4.400


chr1_-_79855209 4.381 Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr3_-_27609279 4.355 NM_173182
Fndc3b
fibronectin type III domain containing 3B
chr4_+_45985143 4.151 Tdrd7
tudor domain containing 7
chr2_-_91489909 4.137 NM_001033451
Zfp408
zinc finger protein 408
chr2_+_91096960 4.038 NM_030880
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr10_-_58684594 4.000 NM_001024910
NM_001024911
Sept10

septin 10

chr12_-_102988510 3.991 Fbln5
fibulin 5
chr7_-_30954705 3.910 NM_011980
Zfp146
zinc finger protein 146
chr3_+_90341208 3.905 S100a16
S100 calcium binding protein A16
chr2_+_91096984 3.901 Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chrX_-_130223380 3.888 NM_001105245
NM_001105246
Pcdh19

protocadherin 19

chr10_-_57252251 3.886 Serinc1
serine incorporator 1
chr5_-_77836974 3.807 Igfbp7
insulin-like growth factor binding protein 7
chr10_-_57252184 3.784 Serinc1
serine incorporator 1
chr1_-_79855229 3.724 NM_009255
Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr2_+_91490332 3.661 Arhgap1
Rho GTPase activating protein 1
chr11_+_100277007 3.647 NM_001163481
NM_010221
Fkbp10

FK506 binding protein 10

chr2_+_91490266 3.617 NM_001145902
Arhgap1
Rho GTPase activating protein 1
chr10_-_57252252 3.608 NM_019760
Serinc1
serine incorporator 1
chr8_-_87323958 3.583 Nfix
nuclear factor I/X
chr10_-_31329530 3.518 NM_001146349
Rnf217
ring finger protein 217
chr8_-_87323896 3.482 Nfix
nuclear factor I/X
chr10_+_40603330 3.467 NM_031877
Wasf1
WASP family 1
chr19_+_3708309 3.335 NM_028077
1810055G02Rik
RIKEN cDNA 1810055G02 gene
chr16_+_15887375 3.310 NM_007679
Cebpd
CCAAT/enhancer binding protein (C/EBP), delta
chr12_+_8778152 3.299 Sdc1
syndecan 1
chr1_+_62750471 3.291 Nrp2
neuropilin 2
chr2_+_33097791 3.280 Angptl2
angiopoietin-like 2
chr1_-_37486768 3.252 NM_198006
6330578E17Rik
RIKEN cDNA 6330578E17 gene
chr7_-_117129643 3.238 Tmem41b
transmembrane protein 41B
chr18_-_60760126 3.152 Synpo
synaptopodin
chr7_+_52825672 3.115 NM_009737
Bcat2
branched chain aminotransferase 2, mitochondrial
chr12_+_8778201 3.094 NM_011519
Sdc1
syndecan 1
chr2_-_155340538 3.086 NM_144786
Ggt7
gamma-glutamyltransferase 7
chr15_+_40486630 3.073 Zfpm2
zinc finger protein, multitype 2
chr1_-_194681914 3.069 NM_198247
Sertad4
SERTA domain containing 4
chr1_+_62749850 3.055 NM_001077403
NM_001077404
NM_001077405
NM_001077406
NM_001077407
NM_010939
Nrp2





neuropilin 2





chr6_-_82724366 3.023 NM_013820
Hk2
hexokinase 2
chr7_-_151656610 3.005 NM_007803
Cttn
cortactin
chr18_+_61204798 3.003 NM_001146268
NM_008809
Pdgfrb

platelet derived growth factor receptor, beta polypeptide

chr17_-_46168654 2.982 Vegfa
vascular endothelial growth factor A
chr5_-_124981025 2.977 Rilpl1
Rab interacting lysosomal protein-like 1
chr11_+_53333270 2.968 NM_033144
Sept8
septin 8
chr18_-_60760086 2.942 Synpo
synaptopodin
chr3_+_121129396 2.940 NM_028044
Cnn3
calponin 3, acidic
chr3_+_121129502 2.925 Cnn3
calponin 3, acidic
chr2_+_109514856 2.923 NM_007540
Bdnf
brain derived neurotrophic factor
chr2_+_167514414 2.908 NM_009883
Cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr1_-_45559866 2.902 Col5a2
collagen, type V, alpha 2
chr10_-_79869505 2.881 NM_025650
Uqcr11
ubiquinol-cytochrome c reductase, complex III subunit XI
chr12_+_8778260 2.860 Sdc1
syndecan 1
chr19_-_4439350 2.832 NM_007485
Rhod
ras homolog gene family, member D
chrX_+_147481712 2.823 NM_008001
Fgd1
FYVE, RhoGEF and PH domain containing 1
chr14_+_103446193 2.800 Irg1
immunoresponsive gene 1
chr16_-_94748235 2.798 NM_007834
Dscr3
Down syndrome critical region gene 3
chr3_+_90346956 2.778 S100a16
S100 calcium binding protein A16
chr4_+_86221615 2.776 Rraga
Ras-related GTP binding A
chr18_-_16967100 2.774 Cdh2
cadherin 2
chr4_+_86221552 2.751 NM_178376
Rraga
Ras-related GTP binding A
chr9_-_29219382 2.748 Ntm
neurotrimin
chr2_+_83564553 2.741 NM_008402
Itgav
integrin alpha V
chr7_-_119301920 2.714 Dkk3
dickkopf homolog 3 (Xenopus laevis)
chr5_+_104864168 2.711 Spp1
secreted phosphoprotein 1
chr2_+_167514460 2.706 Cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr3_+_68272097 2.699 Schip1
schwannomin interacting protein 1
chr8_-_72425538 2.682 Ndufa13
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13
chr15_-_83002561 2.667 Cyb5r3
cytochrome b5 reductase 3
chr6_+_81991613 2.658 NM_145570
Fam176a
family with sequence similarity 176, member A
chr2_+_167514489 2.653 Cebpb
CCAAT/enhancer binding protein (C/EBP), beta
chr9_+_106356125 2.648 NM_021567
Pcbp4
poly(rC) binding protein 4
chr8_+_47556353 2.638 NM_007981
Acsl1
acyl-CoA synthetase long-chain family member 1
chr4_+_104829867 2.597 Ppap2b
phosphatidic acid phosphatase type 2B
chr5_-_5514787 2.573 NM_001193660
NM_001193659
NM_001193661
NM_022890
Cldn12



claudin 12



chr3_-_102007885 2.562 NM_001165951
Vangl1
vang-like 1 (van gogh, Drosophila)
chr7_-_117129702 2.561 NM_153525
Tmem41b
transmembrane protein 41B
chr4_+_136025675 2.560 NM_024452
Luzp1
leucine zipper protein 1
chr7_-_126138572 2.547 Gprc5b
G protein-coupled receptor, family C, group 5, member B
chr7_-_107805365 2.544 Plekhb1
pleckstrin homology domain containing, family B (evectins) member 1
chr1_-_133421746 2.527 Srgap2
SLIT-ROBO Rho GTPase activating protein 2
chr8_-_87324043 2.520 NM_001081982
NM_010906
Nfix

nuclear factor I/X

chr10_+_38685309 2.516 NM_010681
Lama4
laminin, alpha 4
chr3_+_89222501 2.493 Shc1
src homology 2 domain-containing transforming protein C1
chr14_+_77556569 2.491 Enox1
ecto-NOX disulfide-thiol exchanger 1
chr10_-_70386552 2.476 Bicc1
bicaudal C homolog 1 (Drosophila)
chr7_-_107805466 2.469 NM_001163186
NM_001163187
Plekhb1

pleckstrin homology domain containing, family B (evectins) member 1

chr14_+_103446209 2.468 NM_008392
Irg1
immunoresponsive gene 1
chr4_+_86221626 2.463 Rraga
Ras-related GTP binding A
chr2_+_164312087 2.460 Dbndd2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr13_-_76081244 2.438 NM_028493
Rhobtb3
Rho-related BTB domain containing 3
chr9_-_119002601 2.438 NM_019676
Plcd1
phospholipase C, delta 1
chr9_-_110310638 2.433 NM_001081043
Ptpn23
protein tyrosine phosphatase, non-receptor type 23
chr5_-_5514729 2.416 Cldn12
claudin 12
chr15_-_102008126 2.415


chr7_+_150255257 2.413 NM_001115085
NM_020285
NM_138631
Tssc4


tumor-suppressing subchromosomal transferable fragment 4


chr18_-_34166105 2.407 Epb4.1l4a
erythrocyte protein band 4.1-like 4a
chr15_-_83002624 2.402 NM_029787
Cyb5r3
cytochrome b5 reductase 3
chr16_-_52452766 2.399 Alcam
activated leukocyte cell adhesion molecule
chr3_+_68298129 2.399 Schip1
schwannomin interacting protein 1
chr1_-_51972771 2.392 Myo1b
myosin IB
chr1_-_51972718 2.390 Myo1b
myosin IB
chr15_-_56526052 2.387 NM_008216
Has2
hyaluronan synthase 2
chr4_-_124527811 2.386 NM_001142727
1110065P20Rik
RIKEN cDNA 1110065P20 gene
chr12_-_102988893 2.381 Fbln5
fibulin 5
chr19_-_6984541 2.376 Prdx5
peroxiredoxin 5
chr11_-_101286641 2.372 NM_026865
1700113I22Rik
RIKEN cDNA 1700113I22 gene
chr1_-_51972816 2.355 NM_001161817
NM_010863
Myo1b

myosin IB

chr19_-_10599581 2.347 NM_025333
Sdhaf2
succinate dehydrogenase complex assembly factor 2
chr19_-_6984433 2.343 Prdx5
peroxiredoxin 5
chr4_+_80556574 2.338 NM_026821
D4Bwg0951e
DNA segment, Chr 4, Brigham & Women's Genetics 0951 expressed
chr9_+_55056740 2.329 NM_028049
Fbxo22
F-box protein 22
chr10_-_79869574 2.309 Uqcr11
ubiquinol-cytochrome c reductase, complex III subunit XI
chr17_+_80014532 2.300 Fam82a1
family with sequence similarity 82, member A1
chr18_-_25912453 2.299 NM_001146292
NM_001146293
NM_001146294
NM_001146295
NM_001174074
NM_133195
Celf4





CUGBP, Elav-like family member 4





chr2_+_83564607 2.292 Itgav
integrin alpha V
chr3_+_129235284 2.277 NM_130450
Elovl6
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr10_+_110357230 2.276 NM_007792
Csrp2
cysteine and glycine-rich protein 2
chr2_-_152657392 2.275 Bcl2l1
BCL2-like 1
chr9_-_119002573 2.261 Plcd1
phospholipase C, delta 1
chr13_-_19711409 2.244 NM_134065
Epdr1
ependymin related protein 1 (zebrafish)
chr4_+_149611305 2.239 NM_023119
Eno1
enolase 1, alpha non-neuron
chr2_+_32631305 2.234 NM_178595
Ptrh1
peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae)
chr2_+_118752232 2.232 NM_028117
Chst14
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 14
chr19_-_30249899 2.223 NM_138595
Gldc
glycine decarboxylase
chr15_-_66801093 2.221 Ndrg1
N-myc downstream regulated gene 1
chr13_-_115249048 2.215 Fst
follistatin
chr15_+_78859949 2.208


chr14_+_77556622 2.205 NM_172813
Enox1
ecto-NOX disulfide-thiol exchanger 1
chrX_+_69062091 2.204 NM_001081356
Vma21
VMA21 vacuolar H+-ATPase homolog (S. cerevisiae)
chr5_-_136387191 2.178 Ywhag
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma polypeptide
chr15_+_78860043 2.165 H1f0
H1 histone family, member 0
chr5_-_4757914 2.157 Fzd1
frizzled homolog 1 (Drosophila)
chr18_-_13100228 2.156 NM_207530
Osbpl1a
oxysterol binding protein-like 1A
chr16_-_85080242 2.156 App
amyloid beta (A4) precursor protein
chr13_-_100286521 2.152 NM_008634
Mtap1b
microtubule-associated protein 1B
chr10_+_38685424 2.147 Lama4
laminin, alpha 4
chr14_-_63796620 2.126 NM_010191
Fdft1
farnesyl diphosphate farnesyl transferase 1
chr2_-_80421054 2.122 NM_016965
Nckap1
NCK-associated protein 1
chr7_-_126138689 2.121 NM_001195774
NM_022420
Gprc5b

G protein-coupled receptor, family C, group 5, member B

chr6_-_124867962 2.120 NM_026988
Ptms
parathymosin
chr5_-_123064483 2.120 NM_009879
Ift81
intraflagellar transport 81 homolog (Chlamydomonas)
chr11_+_5855721 2.113 NM_019661
Ykt6
YKT6 homolog (S. Cerevisiae)
chr17_+_87153083 2.112 NM_010137
Epas1
endothelial PAS domain protein 1
chr16_-_94747998 2.105 Dscr3
Down syndrome critical region gene 3
chr3_+_126300163 2.105 Camk2d
calcium/calmodulin-dependent protein kinase II, delta
chr3_+_55046548 2.099 Dclk1
doublecortin-like kinase 1
chr3_+_89195758 2.098


chr1_-_165242552 2.096 Prrx1
paired related homeobox 1
chr6_-_29559792 2.089 Tnpo3
transportin 3
chr3_+_89222458 2.085 NM_011368
Shc1
src homology 2 domain-containing transforming protein C1
chr8_-_26127376 2.084 NM_007404
Adam9
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr16_+_16213397 2.062 Pkp2
plakophilin 2
chr1_-_121318824 2.058 NM_008381
Inhbb
inhibin beta-B
chr10_-_126626878 2.056 NM_001166413
NM_028027
Arhgef25

Rho guanine nucleotide exchange factor (GEF) 25

chr8_-_94325138 2.052 NM_008393
Irx3
Iroquois related homeobox 3 (Drosophila)
chr11_-_120593289 2.043 Cbr2
carbonyl reductase 2
chr15_+_6336747 2.040 NM_001037905
NM_001102400
NM_023118
Dab2


disabled homolog 2 (Drosophila)


chr8_+_116159485 2.039 NM_001048143
NM_173015
Mon1b

MON1 homolog b (yeast)

chr2_-_30758745 2.034 Ptges
prostaglandin E synthase
chr8_-_108489925 2.033 NM_009195
Slc12a4
solute carrier family 12, member 4
chr6_+_5675638 2.033 NM_001191023
NM_001191025
NM_001191026
NM_001191027
NM_010063
Dync1i1




dynein cytoplasmic 1 intermediate chain 1




chr11_-_50641191 2.029 NM_013922
Zfp354c
zinc finger protein 354C
chr1_+_51346086 2.023 Sdpr
serum deprivation response
chr2_+_25258653 2.022 Npdc1
neural proliferation, differentiation and control gene 1
chr13_-_53568111 2.018 NM_013601
Msx2
homeobox, msh-like 2
chr5_-_124981292 2.013 NM_021430
Rilpl1
Rab interacting lysosomal protein-like 1
chr16_-_94748040 2.012 Dscr3
Down syndrome critical region gene 3
chr5_+_104864136 2.011 NM_009263
Spp1
secreted phosphoprotein 1
chr1_+_89991575 2.010 NM_201642
Ugt1a7c
UDP glucuronosyltransferase 1 family, polypeptide A7C
chr2_-_152657417 2.006 NM_009743
Bcl2l1
BCL2-like 1
chr12_+_86940000 2.005 Jdp2
Jun dimerization protein 2
chr1_+_51346108 1.988 Sdpr
serum deprivation response
chr11_+_76015590 1.988 Fam57a
family with sequence similarity 57, member A
chr16_+_6349108 1.983 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr8_-_26127211 1.976 Adam9
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr13_+_31898612 1.956 Foxc1
forkhead box C1
chr11_+_66915650 1.949


chr17_-_78817348 1.941 NM_199448
Fez2
fasciculation and elongation protein zeta 2 (zygin II)
chr6_+_15670660 1.941 NM_175088
Mdfic
MyoD family inhibitor domain containing
chr17_-_25981402 1.933 Rhot2
ras homolog gene family, member T2
chr17_+_80014390 1.925 Fam82a1
family with sequence similarity 82, member A1
chr18_-_60783946 1.920 NM_177340
Synpo
synaptopodin
chr11_+_5761862 1.918 NM_009636
Aebp1
AE binding protein 1
chr16_-_46496886 1.917 NM_021495
NM_021496
NM_021497
Pvrl3


poliovirus receptor-related 3


chr8_+_26629214 1.916 NM_001079908
NM_001079909
NM_010206
Fgfr1


fibroblast growth factor receptor 1


chr7_-_126138646 1.907 Gprc5b
G protein-coupled receptor, family C, group 5, member B
chr11_-_120588536 1.902 NM_026428
Dcxr
dicarbonyl L-xylulose reductase

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.48 1.04e-20 GO:0051179 localization
1.51 3.13e-19 GO:0006810 transport
1.50 1.13e-18 GO:0051234 establishment of localization
1.50 1.06e-15 GO:0048731 system development
1.45 4.58e-15 GO:0048856 anatomical structure development
1.47 1.57e-14 GO:0048522 positive regulation of cellular process
1.43 8.76e-14 GO:0048518 positive regulation of biological process
1.41 1.29e-13 GO:0007275 multicellular organismal development
1.38 2.34e-13 GO:0032502 developmental process
1.48 1.46e-12 GO:0048523 negative regulation of cellular process
1.68 1.63e-12 GO:0007399 nervous system development
1.44 6.26e-12 GO:0048519 negative regulation of biological process
1.71 7.93e-12 GO:0051641 cellular localization
1.39 1.24e-11 GO:0016043 cellular component organization
1.77 2.20e-11 GO:0051649 establishment of localization in cell
1.58 9.03e-11 GO:0009653 anatomical structure morphogenesis
1.36 1.28e-10 GO:0071840 cellular component organization or biogenesis
1.90 1.70e-10 GO:0046907 intracellular transport
1.44 8.21e-10 GO:0048869 cellular developmental process
1.29 2.16e-09 GO:0019222 regulation of metabolic process
1.44 3.20e-09 GO:0030154 cell differentiation
1.20 8.98e-09 GO:0044237 cellular metabolic process
1.83 1.02e-08 GO:0016192 vesicle-mediated transport
1.30 1.07e-08 GO:0031323 regulation of cellular metabolic process
1.11 1.24e-08 GO:0009987 cellular process
1.18 3.26e-08 GO:0008152 metabolic process
1.29 4.29e-08 GO:0080090 regulation of primary metabolic process
1.44 6.66e-08 GO:0048513 organ development
1.51 1.40e-07 GO:0031325 positive regulation of cellular metabolic process
1.47 7.15e-07 GO:0009893 positive regulation of metabolic process
1.18 9.98e-07 GO:0044238 primary metabolic process
1.62 1.49e-06 GO:0022008 neurogenesis
1.64 1.73e-06 GO:0048699 generation of neurons
1.27 3.67e-06 GO:0060255 regulation of macromolecule metabolic process
1.58 5.19e-06 GO:0009888 tissue development
1.44 5.40e-06 GO:0023051 regulation of signaling
1.46 6.68e-06 GO:0010604 positive regulation of macromolecule metabolic process
1.59 7.99e-06 GO:0051128 regulation of cellular component organization
1.38 8.78e-06 GO:0065008 regulation of biological quality
1.34 1.11e-05 GO:0071842 cellular component organization at cellular level
1.51 2.32e-05 GO:0032879 regulation of localization
1.46 2.70e-05 GO:0033036 macromolecule localization
1.49 3.41e-05 GO:0010646 regulation of cell communication
1.41 3.65e-05 GO:0065009 regulation of molecular function
1.45 5.35e-05 GO:0009966 regulation of signal transduction
1.32 5.35e-05 GO:0071841 cellular component organization or biogenesis at cellular level
1.70 6.00e-05 GO:0010647 positive regulation of cell communication
1.64 6.52e-05 GO:0042325 regulation of phosphorylation
1.69 8.32e-05 GO:0023056 positive regulation of signaling
1.50 9.04e-05 GO:0032268 regulation of cellular protein metabolic process
1.62 9.72e-05 GO:0019220 regulation of phosphate metabolic process
1.62 9.72e-05 GO:0051174 regulation of phosphorus metabolic process
1.38 1.02e-04 GO:0048583 regulation of response to stimulus
1.57 1.03e-04 GO:0031399 regulation of protein modification process
1.78 1.09e-04 GO:0016044 cellular membrane organization
1.63 1.13e-04 GO:0009887 organ morphogenesis
1.48 1.26e-04 GO:0008104 protein localization
1.53 1.31e-04 GO:0048468 cell development
1.77 1.39e-04 GO:0061024 membrane organization
1.51 1.54e-04 GO:0042127 regulation of cell proliferation
1.55 1.69e-04 GO:0015031 protein transport
1.48 2.46e-04 GO:0009891 positive regulation of biosynthetic process
2.54 3.33e-04 GO:0048193 Golgi vesicle transport
1.73 3.51e-04 GO:0007417 central nervous system development
1.63 3.56e-04 GO:0001932 regulation of protein phosphorylation
1.46 3.91e-04 GO:0050793 regulation of developmental process
1.53 4.09e-04 GO:0045184 establishment of protein localization
1.45 4.46e-04 GO:0051246 regulation of protein metabolic process
1.53 5.07e-04 GO:0044093 positive regulation of molecular function
2.20 5.30e-04 GO:0051493 regulation of cytoskeleton organization
1.18 6.23e-04 GO:0044260 cellular macromolecule metabolic process
1.48 1.01e-03 GO:0010557 positive regulation of macromolecule biosynthetic process
1.75 1.07e-03 GO:0090066 regulation of anatomical structure size
1.48 1.11e-03 GO:2000026 regulation of multicellular organismal development
1.68 1.16e-03 GO:0070727 cellular macromolecule localization
2.04 1.17e-03 GO:0044087 regulation of cellular component biogenesis
1.46 1.25e-03 GO:0031328 positive regulation of cellular biosynthetic process
1.63 1.44e-03 GO:0072358 cardiovascular system development
1.63 1.44e-03 GO:0072359 circulatory system development
1.66 1.48e-03 GO:0009967 positive regulation of signal transduction
1.36 1.53e-03 GO:0051239 regulation of multicellular organismal process
1.25 1.55e-03 GO:0009889 regulation of biosynthetic process
1.67 1.62e-03 GO:0034613 cellular protein localization
1.51 1.84e-03 GO:0051049 regulation of transport
1.16 2.00e-03 GO:0043170 macromolecule metabolic process
1.64 2.45e-03 GO:0030030 cell projection organization
1.61 2.74e-03 GO:0051094 positive regulation of developmental process
1.45 3.19e-03 GO:0051173 positive regulation of nitrogen compound metabolic process
1.72 3.90e-03 GO:0051960 regulation of nervous system development
1.77 4.06e-03 GO:0032535 regulation of cellular component size
1.45 4.84e-03 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.66 5.10e-03 GO:0060341 regulation of cellular localization
1.84 5.51e-03 GO:0045664 regulation of neuron differentiation
1.24 6.04e-03 GO:0031326 regulation of cellular biosynthetic process
1.75 6.52e-03 GO:0006886 intracellular protein transport
1.75 6.52e-03 GO:0050767 regulation of neurogenesis
2.14 7.12e-03 GO:0042692 muscle cell differentiation
1.94 7.14e-03 GO:0071495 cellular response to endogenous stimulus
1.74 7.28e-03 GO:0007420 brain development
1.75 8.28e-03 GO:0031175 neuron projection development
1.23 8.98e-03 GO:0051171 regulation of nitrogen compound metabolic process
2.77 1.03e-02 GO:0051494 negative regulation of cytoskeleton organization
1.73 1.04e-02 GO:0035295 tube development
1.79 1.05e-02 GO:0048568 embryonic organ development
3.35 1.06e-02 GO:0043242 negative regulation of protein complex disassembly
1.77 1.06e-02 GO:0001568 blood vessel development
1.60 1.21e-02 GO:0071310 cellular response to organic substance
1.69 1.22e-02 GO:0008285 negative regulation of cell proliferation
1.23 1.32e-02 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.73 1.32e-02 GO:0001944 vasculature development
3.07 1.34e-02 GO:0043244 regulation of protein complex disassembly
2.73 1.37e-02 GO:0071383 cellular response to steroid hormone stimulus
1.46 1.74e-02 GO:0048584 positive regulation of response to stimulus
2.21 1.80e-02 GO:0043410 positive regulation of MAPKKK cascade
1.55 1.87e-02 GO:0030182 neuron differentiation
1.45 1.87e-02 GO:0051254 positive regulation of RNA metabolic process
3.64 2.40e-02 GO:0006888 ER to Golgi vesicle-mediated transport
1.38 2.53e-02 GO:0010941 regulation of cell death
1.44 2.66e-02 GO:0045595 regulation of cell differentiation
1.71 2.97e-02 GO:0046903 secretion
1.79 3.12e-02 GO:0061061 muscle structure development
1.22 3.29e-02 GO:0010556 regulation of macromolecule biosynthetic process
1.82 3.45e-02 GO:0032880 regulation of protein localization
1.61 3.56e-02 GO:0009719 response to endogenous stimulus
2.65 3.81e-02 GO:0009755 hormone-mediated signaling pathway
1.90 3.85e-02 GO:0032870 cellular response to hormone stimulus
2.96 4.18e-02 GO:0043401 steroid hormone mediated signaling pathway
1.42 4.57e-02 GO:0009790 embryo development
1.60 4.73e-02 GO:0048666 neuron development
1.47 4.75e-02 GO:0007154 cell communication
1.34 4.79e-02 GO:0050790 regulation of catalytic activity

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.27 1.78e-50 GO:0005622 intracellular
1.28 6.20e-49 GO:0044424 intracellular part
1.35 3.97e-45 GO:0005737 cytoplasm
1.40 8.30e-32 GO:0044444 cytoplasmic part
1.26 8.76e-32 GO:0043226 organelle
1.26 1.36e-31 GO:0043229 intracellular organelle
1.25 4.60e-24 GO:0043231 intracellular membrane-bounded organelle
1.25 4.72e-24 GO:0043227 membrane-bounded organelle
1.11 4.53e-21 GO:0005623 cell
1.11 4.53e-21 GO:0044464 cell part
1.28 3.78e-10 GO:0044446 intracellular organelle part
1.35 5.32e-10 GO:0043234 protein complex
1.27 1.83e-09 GO:0044422 organelle part
1.49 2.29e-09 GO:0005739 mitochondrion
1.30 5.85e-09 GO:0032991 macromolecular complex
1.48 9.55e-09 GO:0005856 cytoskeleton
1.48 1.26e-08 GO:0005829 cytosol
1.56 1.88e-08 GO:0042995 cell projection
1.86 2.52e-08 GO:0045202 synapse
1.58 1.10e-07 GO:0044430 cytoskeletal part
1.50 1.95e-07 GO:0000267 cell fraction
1.99 2.79e-07 GO:0044456 synapse part
1.69 4.97e-07 GO:0030054 cell junction
1.24 3.92e-06 GO:0071944 cell periphery
1.35 8.57e-06 GO:0044459 plasma membrane part
1.44 1.21e-05 GO:0031090 organelle membrane
2.43 1.66e-05 GO:0019717 synaptosome
1.50 1.76e-05 GO:0005626 insoluble fraction
1.23 2.68e-05 GO:0005886 plasma membrane
1.51 2.87e-05 GO:0005624 membrane fraction
1.52 6.68e-05 GO:0012505 endomembrane system
1.81 7.37e-05 GO:0044297 cell body
1.61 9.21e-05 GO:0043005 neuron projection
1.27 1.62e-04 GO:0043228 non-membrane-bounded organelle
1.27 1.62e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.44 2.83e-04 GO:0005794 Golgi apparatus
1.57 8.17e-04 GO:0044429 mitochondrial part
1.75 8.39e-04 GO:0043025 neuronal cell body
1.51 1.69e-03 GO:0031975 envelope
2.05 2.27e-03 GO:0045211 postsynaptic membrane
2.53 2.41e-03 GO:0014069 postsynaptic density
1.99 3.09e-03 GO:0031252 cell leading edge
1.49 3.93e-03 GO:0031967 organelle envelope
1.75 4.01e-03 GO:0015629 actin cytoskeleton
1.60 4.12e-03 GO:0005740 mitochondrial envelope
1.61 4.54e-03 GO:0031966 mitochondrial membrane
1.50 6.94e-03 GO:0015630 microtubule cytoskeleton
1.14 8.30e-03 GO:0005634 nucleus
1.70 1.26e-02 GO:0030425 dendrite
1.68 1.36e-02 GO:0048471 perinuclear region of cytoplasm
1.35 1.41e-02 GO:0005783 endoplasmic reticulum
2.60 1.84e-02 GO:0030117 membrane coat
2.60 1.84e-02 GO:0048475 coated membrane
1.68 1.94e-02 GO:0044431 Golgi apparatus part
1.90 2.78e-02 GO:0030135 coated vesicle
1.62 3.65e-02 GO:0005743 mitochondrial inner membrane

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.39 1.47e-31 GO:0005515 protein binding
1.20 2.07e-25 GO:0005488 binding
1.94 1.67e-10 GO:0008092 cytoskeletal protein binding
1.62 3.33e-06 GO:0046983 protein dimerization activity
1.94 4.39e-05 GO:0046982 protein heterodimerization activity
1.83 4.16e-04 GO:0003779 actin binding
1.40 1.91e-03 GO:0005102 receptor binding
2.25 6.02e-03 GO:0015631 tubulin binding
1.66 6.53e-03 GO:0032403 protein complex binding
1.44 6.98e-03 GO:0001071 nucleic acid binding transcription factor activity
1.44 6.98e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.40 1.33e-02 GO:0019899 enzyme binding
1.53 2.50e-02 GO:0042803 protein homodimerization activity
2.39 2.70e-02 GO:0008017 microtubule binding