Motif ID: ESR1.p2

Z-value: 1.311


Transcription factors associated with ESR1.p2:

Gene SymbolEntrez IDGene Name
Esr1 13982 estrogen receptor 1 (alpha)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Esr1chr10_-_57344480.046.0e-01Click!


Activity profile for motif ESR1.p2.

activity profile for motif ESR1.p2


Sorted Z-values histogram for motif ESR1.p2

Sorted Z-values for motif ESR1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ESR1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr9_-_31019412 17.815 Aplp2
amyloid beta (A4) precursor-like protein 2
chr17_-_25981795 17.445 NM_145999
Rhot2
ras homolog gene family, member T2
chr9_+_69137694 14.819 Rora
RAR-related orphan receptor alpha
chr1_+_45402907 13.841 Col3a1
collagen, type III, alpha 1
chr9_+_69137659 13.780 Rora
RAR-related orphan receptor alpha
chr9_-_31019392 13.645 NM_001102455
NM_001102456
NM_009691
Aplp2


amyloid beta (A4) precursor-like protein 2


chr17_-_25981402 13.278 Rhot2
ras homolog gene family, member T2
chr9_-_31019234 12.739 Aplp2
amyloid beta (A4) precursor-like protein 2
chr5_-_77837037 12.535 NM_001159518
NM_008048
Igfbp7

insulin-like growth factor binding protein 7

chr1_+_137625754 11.460 NM_007791
Csrp1
cysteine and glycine-rich protein 1
chr14_-_76956445 11.381 NM_001160326
Serp2
stress-associated endoplasmic reticulum protein family member 2
chr4_+_137237557 11.198 NM_001081155
Rap1gap
Rap1 GTPase-activating protein
chr15_+_54402914 10.450 NM_178920
Mal2
mal, T-cell differentiation protein 2
chr15_+_54402988 10.334 Mal2
mal, T-cell differentiation protein 2
chr6_-_58857000 10.304 NM_021432
Nap1l5
nucleosome assembly protein 1-like 5
chr9_+_43875175 10.293 Usp2
ubiquitin specific peptidase 2
chr9_-_86589782 9.877 NM_008615
Me1
malic enzyme 1, NADP(+)-dependent, cytosolic
chr11_+_100436316 9.678 Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr18_+_24867945 9.458 NM_175276
Fhod3
formin homology 2 domain containing 3
chr8_+_71404491 9.307 Lpl
lipoprotein lipase
chr11_+_100436283 9.182 Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr9_-_50583599 9.121 1110032A03Rik
RIKEN cDNA 1110032A03 gene
chr11_-_83882063 9.096 Dusp14
dual specificity phosphatase 14
chr1_-_95532242 9.047 Stk25
serine/threonine kinase 25 (yeast)
chr2_-_130468507 8.801 NM_197945
Prosapip1
ProSAPiP1 protein
chr11_+_94808758 8.791 Col1a1
collagen, type I, alpha 1
chr1_-_95532270 8.767 Stk25
serine/threonine kinase 25 (yeast)
chr8_+_114464651 8.637


chr3_-_10208575 8.637 NM_024406
Fabp4
fatty acid binding protein 4, adipocyte
chr11_+_100436228 8.592 NM_009923
Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr1_-_95532227 8.541 Stk25
serine/threonine kinase 25 (yeast)
chr3_-_97672147 8.515 NM_177145
Pde4dip
phosphodiesterase 4D interacting protein (myomegalin)
chr7_+_71646515 8.476 NM_007461
Apba2
amyloid beta (A4) precursor protein-binding, family A, member 2
chr11_+_100436346 8.435 Cnp
2',3'-cyclic nucleotide 3' phosphodiesterase
chr9_+_43875103 8.414 NM_198092
Usp2
ubiquitin specific peptidase 2
chr1_-_95532278 8.380 NM_021537
Stk25
serine/threonine kinase 25 (yeast)
chr1_-_95532192 8.349 Stk25
serine/threonine kinase 25 (yeast)
chr1_-_63223287 8.325 Ndufs1
NADH dehydrogenase (ubiquinone) Fe-S protein 1
chr5_-_77836974 8.206 Igfbp7
insulin-like growth factor binding protein 7
chr11_-_53882433 8.196 NM_019417
Pdlim4
PDZ and LIM domain 4
chr8_+_120807621 8.134 NM_019707
Cdh13
cadherin 13
chr7_-_20281956 8.097


chr1_-_63223190 8.094 Ndufs1
NADH dehydrogenase (ubiquinone) Fe-S protein 1
chr3_+_52845429 7.964 NM_175386
Lhfp
lipoma HMGIC fusion partner
chr8_+_11312828 7.932 NM_009932
Col4a2
collagen, type IV, alpha 2
chr2_+_25251393 7.870 NM_009849
Entpd2
ectonucleoside triphosphate diphosphohydrolase 2
chr8_+_14095873 7.822 NM_001145965
NM_172910
Dlgap2

discs, large (Drosophila) homolog-associated protein 2

chr18_-_13100228 7.718 NM_207530
Osbpl1a
oxysterol binding protein-like 1A
chr18_+_74602260 7.541 NM_201600
Myo5b
myosin VB
chr11_-_83881811 7.520 NM_019819
Dusp14
dual specificity phosphatase 14
chr1_-_63223345 7.475 NM_001160038
NM_001160039
NM_001160040
NM_145518
Ndufs1



NADH dehydrogenase (ubiquinone) Fe-S protein 1



chr9_+_20970150 7.439 NM_183408
Pde4a
phosphodiesterase 4A, cAMP specific
chr8_+_14095884 7.384 Dlgap2
discs, large (Drosophila) homolog-associated protein 2
chr13_-_69878721 7.352 NM_001145162
Ube2ql1
ubiquitin-conjugating enzyme E2Q family-like 1
chr14_+_3049284 7.272 NM_001177715
NM_001177714
Gm2897

predicted gene 2897

chr1_+_66221851 7.122 NM_001039934
NM_008632
Mtap2

microtubule-associated protein 2

chr14_-_7937970 7.025 NM_001024712
Gm3696
predicted gene 3696
chr19_-_43598949 6.962 NM_010324
Got1
glutamate oxaloacetate transaminase 1, soluble
chr1_+_91351435 6.945 Agap1
ArfGAP with GTPase domain, ankyrin repeat and PH domain 1
chr4_+_149022081 6.775 Clstn1
calsyntenin 1
chr3_+_52845510 6.687 Lhfp
lipoma HMGIC fusion partner
chr7_-_133942767 6.663 NM_007438
Aldoa
aldolase A, fructose-bisphosphate
chr13_-_34437042 6.643 NM_001033167
Slc22a23
solute carrier family 22, member 23
chr11_+_68902025 6.546 NM_009497
Vamp2
vesicle-associated membrane protein 2
chr1_-_75188496 6.504 NM_001003917
Atg9a
autophagy-related 9A (yeast)
chr6_+_4483741 6.353 Col1a2
collagen, type I, alpha 2
chr14_-_8491067 6.293 Gm2897
predicted gene 2897
chr16_-_4419805 6.259 Adcy9
adenylate cyclase 9
chr4_+_149022266 6.217


chr8_+_11313002 6.214 Col4a2
collagen, type IV, alpha 2
chr13_-_24923190 6.164 Acot13
acyl-CoA thioesterase 13
chr18_-_46756837 6.128 NM_025698
Tmed7
transmembrane emp24 protein transport domain containing 7
chr9_-_56008595 6.092 Tspan3
tetraspanin 3
chr1_-_95531961 6.086 Stk25
serine/threonine kinase 25 (yeast)
chr14_-_7859962 6.079 NM_001164727
Gm10406
predicted gene 10406
chr19_+_10463540 6.014 NM_018801
NM_173067
NM_173068
Syt7


synaptotagmin VII


chr17_-_24987239 5.973 NM_023480
Fahd1
fumarylacetoacetate hydrolase domain containing 1
chr6_-_127718746 5.929 NM_201371
Prmt8
protein arginine N-methyltransferase 8
chr10_+_59740373 5.929 NM_001146120
NM_001146121
NM_001146122
NM_001146123
NM_011179
Psap




prosaposin




chr8_-_87323958 5.854 Nfix
nuclear factor I/X
chr9_-_21889810 5.815 NM_012029
Ecsit
ECSIT homolog (Drosophila)
chr8_+_11443165 5.809 Col4a2
collagen, type IV, alpha 2
chr13_-_24923314 5.790 NM_025790
Acot13
acyl-CoA thioesterase 13
chr10_+_59740430 5.771 Psap
prosaposin
chr7_-_4610179 5.769 Ppp6r1
protein phosphatase 6, regulatory subunit 1
chr11_+_68901989 5.739 Vamp2
vesicle-associated membrane protein 2
chr15_-_89255772 5.727 Cpt1b
carnitine palmitoyltransferase 1b, muscle
chr7_+_133415982 5.686 NM_145587
Sbk1
SH3-binding kinase 1
chr8_+_114464639 5.685 Gabarapl2
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2
chr9_-_56008770 5.656 Tspan3
tetraspanin 3
chr7_-_133942605 5.655 NM_001177307
Aldoa
aldolase A, fructose-bisphosphate
chr5_-_124981025 5.614 Rilpl1
Rab interacting lysosomal protein-like 1
chr17_-_24987230 5.613 Fahd1
fumarylacetoacetate hydrolase domain containing 1
chr8_-_87323896 5.556 Nfix
nuclear factor I/X
chr8_-_112692071 5.529 NM_007586
Calb2
calbindin 2
chr10_+_93977597 5.492 NM_172051
Tmcc3
transmembrane and coiled coil domains 3
chr18_-_10706693 5.464 NM_134130
Abhd3
abhydrolase domain containing 3
chr9_-_21889841 5.401 Ecsit
ECSIT homolog (Drosophila)
chr15_-_76648532 5.350 NM_001168288
NM_198420
Arhgap39

Rho GTPase activating protein 39

chr9_-_56008819 5.317 Tspan3
tetraspanin 3
chr11_+_78002309 5.253 Rab34
RAB34, member of RAS oncogene family
chr4_+_42962733 5.227 Dnajb5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr9_-_107571294 5.207 Slc38a3
solute carrier family 38, member 3
chr1_-_71699671 5.142 NM_010233
Fn1
fibronectin 1
chr11_+_94811409 5.141 Col1a1
collagen, type I, alpha 1
chr6_+_138089041 5.120 NM_019946
Mgst1
microsomal glutathione S-transferase 1
chr14_+_66587319 4.973 NM_013492
Clu
clusterin
chr19_-_7292009 4.962 Cox8a
cytochrome c oxidase, subunit VIIIa
chr8_+_114464581 4.914 NM_026693
Gabarapl2
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 2
chr12_-_46175433 4.892 NM_144552
Stxbp6
syntaxin binding protein 6 (amisyn)
chr9_-_56008828 4.869 NM_019793
Tspan3
tetraspanin 3
chr9_-_107569654 4.861 NM_023805
Slc38a3
solute carrier family 38, member 3
chr11_+_78002249 4.825 NM_033475
Rab34
RAB34, member of RAS oncogene family
chr10_-_76086045 4.820 Col6a2
collagen, type VI, alpha 2
chr1_-_137271539 4.815 NM_175259
Shisa4
shisa homolog 4 (Xenopus laevis)
chr6_+_29867012 4.792 NM_001037740
NM_177204
Fam40b

family with sequence similarity 40, member B

chr6_-_124867872 4.785 Ptms
parathymosin
chr10_-_76086144 4.763 NM_146007
Col6a2
collagen, type VI, alpha 2
chr1_+_36748331 4.725 NM_009942
Cox5b
cytochrome c oxidase, subunit Vb
chr9_-_54407955 4.716 Cib2
calcium and integrin binding family member 2
chr10_-_79602040 4.701 Dos
downstream of Stk11
chr11_+_83223154 4.697 Rasl10b
RAS-like, family 10, member B
chr3_-_107320881 4.649 NM_172271
Slc6a17
solute carrier family 6 (neurotransmitter transporter), member 17
chr19_-_7292057 4.636 Cox8a
cytochrome c oxidase, subunit VIIIa
chr7_+_19609771 4.606 Sympk
symplekin
chr16_+_33829715 4.591 NM_001145884
NM_010580
Itgb5

integrin beta 5

chr16_-_4419586 4.575 NM_009624
Adcy9
adenylate cyclase 9
chr4_+_155205723 4.553 NM_025338
Aurkaip1
aurora kinase A interacting protein 1
chr5_+_135485575 4.550 Abhd11
abhydrolase domain containing 11
chr1_-_16509276 4.514 NM_001111272
NM_025303
Stau2

staufen (RNA binding protein) homolog 2 (Drosophila)

chr1_+_36748379 4.491 Cox5b
cytochrome c oxidase, subunit Vb
chr19_-_7292086 4.465 NM_007750
Cox8a
cytochrome c oxidase, subunit VIIIa
chr9_-_79607490 4.442 Cox7a2
cytochrome c oxidase, subunit VIIa 2
chr7_-_86887849 4.385 NM_011068
Pex11a
peroxisomal biogenesis factor 11 alpha
chr7_+_125856066 4.385 NM_182995
6330503K22Rik
RIKEN cDNA 6330503K22 gene
chr18_+_64425037 4.381 St8sia3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3
chr7_-_86887995 4.360 Pex11a
peroxisomal biogenesis factor 11 alpha
chr7_+_19996439 4.353 NM_007710
Ckm
creatine kinase, muscle
chr11_-_102268716 4.348 Slc25a39
solute carrier family 25, member 39
chr5_-_45841382 4.306 NM_024236
Qdpr
quinoid dihydropteridine reductase
chr16_+_18066571 4.283 Dgcr6
DiGeorge syndrome critical region gene 6
chr5_-_124981292 4.207 NM_021430
Rilpl1
Rab interacting lysosomal protein-like 1
chr6_-_38825815 4.162 Hipk2
homeodomain interacting protein kinase 2
chr14_+_47451832 4.143 Cgrrf1
cell growth regulator with ring finger domain 1
chr10_+_59754384 4.138 Psap
prosaposin
chr9_+_43893029 4.125 Usp2
ubiquitin specific peptidase 2
chr5_-_45841351 4.096 Qdpr
quinoid dihydropteridine reductase
chr14_-_24824081 4.094 Kcnma1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr10_+_69488049 4.062 Ank3
ankyrin 3, epithelial
chr6_+_83085799 4.043 NM_001136227
Rtkn
rhotekin
chr3_+_102538849 4.030 Tspan2
tetraspanin 2
chr16_+_18066494 3.990 Dgcr6
DiGeorge syndrome critical region gene 6
chr18_+_53405363 3.949 Snx24
sorting nexing 24
chr1_+_74760162 3.929 Cyp27a1
cytochrome P450, family 27, subfamily a, polypeptide 1
chr7_-_150646758 3.908 Cdkn1c
cyclin-dependent kinase inhibitor 1C (P57)
chr7_-_4610551 3.895 NM_172894
Ppp6r1
protein phosphatase 6, regulatory subunit 1
chr11_+_98603186 3.881 NM_178060
Thra
thyroid hormone receptor alpha
chr10_-_8605668 3.846 NM_175155
Sash1
SAM and SH3 domain containing 1
chr10_+_18246228 3.841 Nhsl1
NHS-like 1
chr7_+_19609725 3.840 NM_026605
Sympk
symplekin
chr3_-_69402739 3.827 NM_020026
B3galnt1
UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1
chr12_-_77923303 3.805 NM_134050
Rab15
RAB15, member RAS oncogene family
chr18_+_53405310 3.786 NM_029394
Snx24
sorting nexing 24
chrX_+_7215705 3.777 NM_009305
Syp
synaptophysin
chr5_+_27588579 3.766 Dpp6
dipeptidylpeptidase 6
chr15_-_63891810 3.765 NM_144846
Fam49b
family with sequence similarity 49, member B
chr11_+_115626816 3.757 2310067B10Rik
RIKEN cDNA 2310067B10 gene
chr15_+_34236408 3.756 NM_016762
Matn2
matrilin 2
chr14_-_35315715 3.718 NM_009758
Bmpr1a
bone morphogenetic protein receptor, type 1A
chr9_-_86775282 3.696 Snap91
synaptosomal-associated protein 91
chr9_-_103125934 3.690 Trf
transferrin
chr16_-_97832640 3.689 Tmprss2
transmembrane protease, serine 2
chr9_+_54547344 3.680 NM_021422
Dnaja4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr10_-_87966607 3.661 NM_001146690
NM_144807
Chpt1

choline phosphotransferase 1

chr3_-_10208480 3.656 Fabp4
Fabp9
fatty acid binding protein 4, adipocyte
fatty acid binding protein 9, testis
chr9_-_86775154 3.639 NM_013669
Snap91
synaptosomal-associated protein 91
chr9_+_46036703 3.636 NM_009692
Apoa1
apolipoprotein A-I
chr10_-_70807521 3.635 NM_134007
Cisd1
CDGSH iron sulfur domain 1
chr5_-_148537561 3.634 NM_010228
Flt1
FMS-like tyrosine kinase 1
chr10_-_77626157 3.604 D10Jhu81e
DNA segment, Chr 10, Johns Hopkins University 81 expressed
chr11_-_120442889 3.591 NM_133796
Arhgdia
Rho GDP dissociation inhibitor (GDI) alpha
chr19_+_23216035 3.575 Klf9
Kruppel-like factor 9
chr1_+_94803538 3.571 NM_175118
Dusp28
dual specificity phosphatase 28
chr5_-_137521896 3.514 NM_007457
Ap1s1
adaptor protein complex AP-1, sigma 1
chr10_-_42893894 3.513 Sobp
sine oculis-binding protein homolog (Drosophila)
chr5_+_67698177 3.506 NM_178651
Slc30a9
solute carrier family 30 (zinc transporter), member 9
chr14_-_66743271 3.504 NM_007940
Ephx2
epoxide hydrolase 2, cytoplasmic
chr13_-_56397521 3.501 Cxcl14
chemokine (C-X-C motif) ligand 14
chr10_+_79605038 3.500 NM_025313
Atp5d
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr17_-_66450782 3.482 NM_028388
Ndufv2
NADH dehydrogenase (ubiquinone) flavoprotein 2
chr12_+_109572514 3.450 NM_010010
Cyp46a1
cytochrome P450, family 46, subfamily a, polypeptide 1
chr5_-_31247757 3.435 NM_001160149
NM_026770
Cgref1

cell growth regulator with EF hand domain 1

chr2_-_32837527 3.433 NM_019488
Slc2a8
solute carrier family 2, (facilitated glucose transporter), member 8
chr2_+_22477837 3.425 NM_008078
Gad2
glutamic acid decarboxylase 2
chr19_+_7631935 3.416 NM_139269
Pla2g16
phospholipase A2, group XVI
chr11_+_54128404 3.414 NM_001033599
Acsl6
acyl-CoA synthetase long-chain family member 6
chr16_+_95924069 3.408 Ets2
E26 avian leukemia oncogene 2, 3' domain
chr15_+_89284554 3.379 Mapk8ip2
mitogen-activated protein kinase 8 interacting protein 2
chr8_-_11312729 3.369 NM_009931
Col4a1
collagen, type IV, alpha 1
chr9_+_80012837 3.364 NM_001039546
Myo6
myosin VI

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.49 8.96e-08 GO:0051179 localization
1.53 3.15e-07 GO:0051234 establishment of localization
1.53 3.72e-07 GO:0006810 transport
2.06 6.79e-07 GO:0045184 establishment of protein localization
1.82 1.82e-06 GO:0033036 macromolecule localization
1.87 5.49e-06 GO:0008104 protein localization
2.00 6.33e-06 GO:0015031 protein transport
2.64 1.02e-04 GO:0007264 small GTPase mediated signal transduction
1.62 2.64e-04 GO:0023051 regulation of signaling
1.53 7.06e-04 GO:0065008 regulation of biological quality
1.77 1.22e-03 GO:0042592 homeostatic process
1.94 1.54e-03 GO:0016192 vesicle-mediated transport
1.38 1.78e-03 GO:0016043 cellular component organization
1.37 2.10e-03 GO:0071840 cellular component organization or biogenesis
1.56 2.22e-03 GO:0065009 regulation of molecular function
1.67 3.39e-03 GO:0035556 intracellular signal transduction
1.68 3.70e-03 GO:0051641 cellular localization
1.19 5.35e-03 GO:0008152 metabolic process
1.66 5.38e-03 GO:0032879 regulation of localization
1.59 1.00e-02 GO:0050790 regulation of catalytic activity
1.49 1.03e-02 GO:0044281 small molecule metabolic process
1.59 1.08e-02 GO:0009966 regulation of signal transduction
1.85 1.35e-02 GO:0046907 intracellular transport
1.91 1.43e-02 GO:0019725 cellular homeostasis
1.38 1.74e-02 GO:0048731 system development
1.83 1.75e-02 GO:0048878 chemical homeostasis
1.70 1.88e-02 GO:0051128 regulation of cellular component organization
1.35 2.67e-02 GO:0048856 anatomical structure development
1.20 3.18e-02 GO:0044237 cellular metabolic process
1.32 3.47e-02 GO:0007275 multicellular organismal development
1.97 4.09e-02 GO:0016044 cellular membrane organization
1.51 4.18e-02 GO:0009653 anatomical structure morphogenesis
1.60 4.30e-02 GO:0006796 phosphate metabolic process
1.96 4.60e-02 GO:0061024 membrane organization
1.60 4.63e-02 GO:0006793 phosphorus metabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.46 4.85e-30 GO:0005737 cytoplasm
1.31 1.29e-24 GO:0005622 intracellular
1.56 2.06e-24 GO:0044444 cytoplasmic part
1.30 3.02e-22 GO:0044424 intracellular part
1.16 2.22e-16 GO:0005623 cell
1.16 2.22e-16 GO:0044464 cell part
1.29 2.80e-15 GO:0043229 intracellular organelle
1.29 5.80e-15 GO:0043226 organelle
1.30 8.85e-13 GO:0043227 membrane-bounded organelle
1.30 9.37e-13 GO:0043231 intracellular membrane-bounded organelle
1.80 3.13e-09 GO:0005739 mitochondrion
1.86 2.60e-08 GO:0031090 organelle membrane
2.30 4.89e-08 GO:0043005 neuron projection
2.83 2.59e-07 GO:0030425 dendrite
2.55 1.97e-06 GO:0044297 cell body
1.36 3.65e-06 GO:0044446 intracellular organelle part
1.35 4.61e-06 GO:0044422 organelle part
1.74 4.74e-06 GO:0000267 cell fraction
1.76 8.59e-06 GO:0042995 cell projection
2.50 1.09e-05 GO:0043025 neuronal cell body
1.54 4.14e-05 GO:0044459 plasma membrane part
1.79 5.24e-05 GO:0005626 insoluble fraction
2.08 1.38e-04 GO:0045202 synapse
1.19 1.89e-04 GO:0016020 membrane
1.76 2.25e-04 GO:0005624 membrane fraction
1.79 3.73e-04 GO:0012505 endomembrane system
1.70 5.84e-04 GO:0005794 Golgi apparatus
2.33 6.08e-04 GO:0048471 perinuclear region of cytoplasm
5.00 1.08e-03 GO:0005905 coated pit
2.08 1.12e-03 GO:0031966 mitochondrial membrane
2.06 1.45e-03 GO:0044463 cell projection part
1.90 1.93e-03 GO:0044429 mitochondrial part
1.30 2.42e-03 GO:0005886 plasma membrane
1.29 2.65e-03 GO:0071944 cell periphery
2.14 3.33e-03 GO:0044456 synapse part
1.99 3.48e-03 GO:0005740 mitochondrial envelope
1.80 4.44e-03 GO:0031967 organelle envelope
1.49 4.93e-03 GO:0005829 cytosol
3.75 6.30e-03 GO:0030662 coated vesicle membrane
1.58 6.53e-03 GO:0005783 endoplasmic reticulum
2.66 6.61e-03 GO:0044433 cytoplasmic vesicle part
1.77 6.85e-03 GO:0031975 envelope
2.49 9.11e-03 GO:0045121 membrane raft
1.29 1.16e-02 GO:0032991 macromolecular complex
2.63 1.23e-02 GO:0000139 Golgi membrane
2.49 1.91e-02 GO:0012506 vesicle membrane
2.29 2.01e-02 GO:0016323 basolateral plasma membrane
2.03 2.83e-02 GO:0005743 mitochondrial inner membrane
2.08 2.99e-02 GO:0044431 Golgi apparatus part
1.30 3.52e-02 GO:0043234 protein complex
1.98 3.60e-02 GO:0019866 organelle inner membrane
2.51 3.66e-02 GO:0030659 cytoplasmic vesicle membrane
5.17 3.88e-02 GO:0030120 vesicle coat
2.07 4.11e-02 GO:0015629 actin cytoskeleton
3.16 4.52e-02 GO:0042383 sarcolemma

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.19 1.29e-08 GO:0005488 binding
1.32 7.92e-08 GO:0005515 protein binding
1.45 5.60e-04 GO:0000166 nucleotide binding
2.17 1.45e-03 GO:0032403 protein complex binding
3.05 4.26e-03 GO:0005516 calmodulin binding
1.23 6.44e-03 GO:0003824 catalytic activity
1.66 7.43e-03 GO:0019899 enzyme binding
9.37 8.68e-03 GO:0048407 platelet-derived growth factor binding
1.78 2.42e-02 GO:0004672 protein kinase activity
1.84 2.48e-02 GO:0008324 cation transmembrane transporter activity
2.39 2.60e-02 GO:0022890 inorganic cation transmembrane transporter activity
1.40 2.77e-02 GO:0032553 ribonucleotide binding
1.92 2.86e-02 GO:0060589 nucleoside-triphosphatase regulator activity
1.93 3.10e-02 GO:0030695 GTPase regulator activity
1.40 3.90e-02 GO:0035639 purine ribonucleoside triphosphate binding
1.39 4.09e-02 GO:0032555 purine ribonucleotide binding
2.16 4.54e-02 GO:0005083 small GTPase regulator activity
1.77 4.76e-02 GO:0008092 cytoskeletal protein binding
1.39 4.89e-02 GO:0017076 purine nucleotide binding