Motif ID: ESRRA.p2

Z-value: 2.822


Transcription factors associated with ESRRA.p2:

Gene SymbolEntrez IDGene Name
Esrra 26379 estrogen related receptor, alpha

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Esrrachr19_-_69860370.372.3e-07Click!


Activity profile for motif ESRRA.p2.

activity profile for motif ESRRA.p2


Sorted Z-values histogram for motif ESRRA.p2

Sorted Z-values for motif ESRRA.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of ESRRA.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr2_-_180891448 61.984 Eef1a2
eukaryotic translation elongation factor 1 alpha 2
chr19_-_43598949 58.446 NM_010324
Got1
glutamate oxaloacetate transaminase 1, soluble
chr15_-_83936038 53.731 Sult4a1
sulfotransferase family 4A, member 1
chr12_+_110783593 52.262 Meg3
maternally expressed 3
chr7_-_148615247 48.880 NM_021316
Cend1
cell cycle exit and neuronal differentiation 1
chr12_+_110783786 47.848 Meg3
maternally expressed 3
chr2_+_121183509 44.872 Ckmt1
creatine kinase, mitochondrial 1, ubiquitous
chr9_-_107571294 43.687 Slc38a3
solute carrier family 38, member 3
chr10_+_75398588 43.653 Chchd10
coiled-coil-helix-coiled-coil-helix domain containing 10
chr7_-_31840594 39.712 Fxyd1
FXYD domain-containing ion transport regulator 1
chr2_+_121184334 39.566 NM_009897
Ckmt1
creatine kinase, mitochondrial 1, ubiquitous
chr7_-_31840647 39.110 NM_019503
NM_052992
Fxyd1

FXYD domain-containing ion transport regulator 1

chr2_-_181049204 38.189 NM_009133
Stmn3
stathmin-like 3
chr6_+_48487648 37.385 Atp6v0e2
ATPase, H+ transporting, lysosomal V0 subunit E2
chr15_-_83936183 37.123 NM_013873
Sult4a1
sulfotransferase family 4A, member 1
chr6_+_48487567 36.151 NM_133764
Atp6v0e2
ATPase, H+ transporting, lysosomal V0 subunit E2
chr6_-_142456402 35.512 NM_008492
Ldhb
lactate dehydrogenase B
chr11_-_3995299 35.489 NM_026443
Mtfp1
mitochondrial fission process 1
chr2_+_177876635 33.395 NM_028806
Phactr3
phosphatase and actin regulator 3
chr12_+_103793130 32.860 NM_007693
Chga
chromogranin A
chr9_-_69989168 32.813 Fam81a
family with sequence similarity 81, member A
chr3_+_68376319 32.739 Schip1
schwannomin interacting protein 1
chr15_+_68758773 31.396 NM_010158
Khdrbs3
KH domain containing, RNA binding, signal transduction associated 3
chr2_+_177876710 31.328 Phactr3
phosphatase and actin regulator 3
chr3_-_97628441 31.205 NM_001110163
Pde4dip
phosphodiesterase 4D interacting protein (myomegalin)
chr5_-_139606339 30.643 Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr3_+_68376289 29.095 NM_013928
Schip1
schwannomin interacting protein 1
chr19_-_47165086 28.463 NM_023211
Usmg5
upregulated during skeletal muscle growth 5
chrX_+_162782484 28.380 NM_001177955
NM_001177956
NM_001177957
NM_001177958
NM_001177959
NM_001177960
Gpm6b





glycoprotein m6b





chr9_-_107571304 28.219 Slc38a3
solute carrier family 38, member 3
chr18_-_60783889 27.873 Synpo
synaptopodin
chr14_+_14117313 27.357 Synpr
synaptoporin
chr9_+_54434140 25.885 NM_029573
Idh3a
isocitrate dehydrogenase 3 (NAD+) alpha
chr17_-_23908488 25.565 NM_153791
Flywch1
FLYWCH-type zinc finger 1
chr5_+_118477803 25.522 NM_021344
Tesc
tescalcin
chr4_-_104782337 25.486 Prkaa2
protein kinase, AMP-activated, alpha 2 catalytic subunit
chr16_+_5884885 25.315 NM_021477
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr5_-_108978950 25.146 NM_007756
Cplx1
complexin 1
chr19_-_47165137 24.380 Usmg5
upregulated during skeletal muscle growth 5
chr12_-_112910475 23.907 NM_021273
Ckb
creatine kinase, brain
chr11_+_68901989 23.692 Vamp2
vesicle-associated membrane protein 2
chr8_-_107995252 23.478 Tppp3
tubulin polymerization-promoting protein family member 3
chr9_+_57758783 23.235 NM_001122873
NM_027086
Ubl7

ubiquitin-like 7 (bone marrow stromal cell-derived)

chr11_+_54117299 23.108 NM_001033598
Acsl6
acyl-CoA synthetase long-chain family member 6
chr12_+_118754951 23.064 NM_175930
Rapgef5
Rap guanine nucleotide exchange factor (GEF) 5
chr6_+_91106773 22.782 NM_144919
Hdac11
histone deacetylase 11
chr6_-_113991945 22.689 NM_009723
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr1_-_169323901 22.684 NM_025569
Mgst3
microsomal glutathione S-transferase 3
chr8_+_97296066 22.484 NM_009142
Cx3cl1
chemokine (C-X3-C motif) ligand 1
chr9_-_44728790 22.467 NM_013795
Atp5l
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g
chr9_-_44728786 22.455 Atp5l
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g
chr5_+_64040341 22.324 NM_177006
3110047P20Rik
RIKEN cDNA 3110047P20 gene
chr1_-_137268058 22.002 Shisa4
shisa homolog 4 (Xenopus laevis)
chr3_-_87804277 21.921 NM_001109758
NM_007529
Bcan

brevican

chr13_+_118391270 21.808 Hcn1
hyperpolarization-activated, cyclic nucleotide-gated K+ 1
chr8_-_107995282 21.520 NM_026481
Tppp3
tubulin polymerization-promoting protein family member 3
chr19_-_3912710 21.344 NM_144870
Ndufs8
NADH dehydrogenase (ubiquinone) Fe-S protein 8
chr12_+_62625477 21.050 NM_178714
Lrfn5
leucine rich repeat and fibronectin type III domain containing 5
chr9_+_109834266 21.041 NM_008633
Mtap4
microtubule-associated protein 4
chr9_+_50412002 20.827 NM_013897
Timm8b
translocase of inner mitochondrial membrane 8 homolog b (yeast)
chr4_+_84851440 20.628 Sh3gl2
SH3-domain GRB2-like 2
chr3_+_14886681 20.532 Car2
carbonic anhydrase 2
chr11_+_68902025 20.525 NM_009497
Vamp2
vesicle-associated membrane protein 2
chr11_+_42233258 20.477 NM_008070
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr4_+_99602038 20.437 NM_028132
Pgm2
phosphoglucomutase 2
chr13_+_9275741 20.207 NM_001081426
Dip2c
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr2_+_26483976 19.871 NM_019833
Fam69b
family with sequence similarity 69, member B
chr7_+_4071087 19.858 NM_001001454
NM_001109765
NM_021324
Ttyh1


tweety homolog 1 (Drosophila)


chr6_-_5446277 19.380 NM_013743
Pdk4
pyruvate dehydrogenase kinase, isoenzyme 4
chr14_-_13655558 19.378 Cadps
Ca2+-dependent secretion activator
chr10_-_70807521 19.373 NM_134007
Cisd1
CDGSH iron sulfur domain 1
chr6_-_124764170 19.347 Tpi1
triosephosphate isomerase 1
chr4_-_147533696 19.208 NM_001161851
Fbxo44
F-box protein 44
chr8_+_98226914 19.085 NM_001195006
NM_145602
Ndrg4

N-myc downstream regulated gene 4

chr15_+_30102306 18.938 NM_008729
Ctnnd2
catenin (cadherin associated protein), delta 2
chr6_-_124764313 18.834 NM_009415
Tpi1
triosephosphate isomerase 1
chr6_-_124764137 18.637 Tpi1
triosephosphate isomerase 1
chrX_-_50946805 18.224 NM_024170
Cxx1a
CAAX box 1 homolog A (human)
chr16_-_84835213 18.212 Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chrX_-_50973482 18.209 NM_001018063
Cxx1b
CAAX box 1 homolog B (human)
chr14_-_52532988 18.208 Ndrg2
N-myc downstream regulated gene 2
chr9_-_44728745 18.084 Atp5l
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit g
chr12_+_62624880 18.023 Lrfn5
leucine rich repeat and fibronectin type III domain containing 5
chrX_+_154137193 17.698 Smpx
small muscle protein, X-linked
chr4_+_140517161 17.685 NM_023374
Sdhb
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr3_+_14886253 17.598 NM_009801
Car2
carbonic anhydrase 2
chrX_+_154137114 17.514 Smpx
small muscle protein, X-linked
chr13_+_83663817 17.405 Mef2c
myocyte enhancer factor 2C
chr19_-_3912727 17.251 Ndufs8
NADH dehydrogenase (ubiquinone) Fe-S protein 8
chr8_+_97296110 17.183 Cx3cl1
chemokine (C-X3-C motif) ligand 1
chr1_+_74331503 17.139 NM_001039509
NM_025580
Pnkd

paroxysmal nonkinesiogenic dyskinesia

chr2_+_121121189 17.108 NM_001173506
Mtap1a
microtubule-associated protein 1 A
chr3_+_32635988 17.094 Ndufb5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5
chr10_+_93661746 17.082 NM_025551
Ndufa12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr1_+_75542840 17.024 NM_009208
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr7_+_112702873 16.864 NM_011421
Smpd1
sphingomyelin phosphodiesterase 1, acid lysosomal
chr9_+_50412050 16.830 Timm8b
translocase of inner mitochondrial membrane 8 homolog b (yeast)
chr7_-_88851823 16.703 Homer2
homer homolog 2 (Drosophila)
chr9_-_42924626 16.687 NM_001034863
Tmem136
transmembrane protein 136
chr19_+_7070609 16.618 NM_153597
Trpt1
tRNA phosphotransferase 1
chr7_+_4071171 16.560 Ttyh1
tweety homolog 1 (Drosophila)
chr8_-_13494457 16.555 NM_019521
Gas6
growth arrest specific 6
chr8_+_97296093 16.472 Cx3cl1
chemokine (C-X3-C motif) ligand 1
chr17_-_24987038 16.459 Fahd1
fumarylacetoacetate hydrolase domain containing 1
chr18_+_32091098 16.437 NM_144862
Lims2
LIM and senescent cell antigen like domains 2
chr1_+_36748331 16.424 NM_009942
Cox5b
cytochrome c oxidase, subunit Vb
chr11_-_30119771 16.329 NM_175836
Spnb2
spectrin beta 2
chr2_-_155755765 16.293 Uqcc
ubiquinol-cytochrome c reductase complex chaperone, CBP3 homolog (yeast)
chr10_+_93661777 16.191 Ndufa12
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 12
chr17_-_24987063 16.146 Fahd1
fumarylacetoacetate hydrolase domain containing 1
chr17_-_26005680 16.098 NM_026633
Fam195a
family with sequence similarity 195, member A
chr2_+_151931424 15.938 Srxn1
sulfiredoxin 1 homolog (S. cerevisiae)
chr4_-_41720928 15.935 NM_001164045
NM_001048179
NM_001164044
Ccl27a


chemokine (C-C motif) ligand 27A


chr14_-_52533039 15.873 Ndrg2
N-myc downstream regulated gene 2
chr9_-_121701480 15.838 NM_029095
Hhatl
hedgehog acyltransferase-like
chr14_-_13655592 15.818 NM_001042617
NM_012061
Cadps

Ca2+-dependent secretion activator

chr11_+_6963421 15.791 NM_009622
Adcy1
adenylate cyclase 1
chr18_-_42900793 15.790 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr8_-_87461220 15.657 Mast1
microtubule associated serine/threonine kinase 1
chr2_+_151931465 15.448 NM_029688
Srxn1
sulfiredoxin 1 homolog (S. cerevisiae)
chr1_-_79855177 15.292 Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr9_+_109834324 15.227 Mtap4
microtubule-associated protein 4
chr9_-_35018518 15.191 Foxred1
FAD-dependent oxidoreductase domain containing 1
chr3_+_32635972 14.985 NM_025316
Ndufb5
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5
chr11_-_69373707 14.983 NM_007911
Efnb3
ephrin B3
chr9_-_35018552 14.878 Foxred1
FAD-dependent oxidoreductase domain containing 1
chr16_+_17276384 14.745 NM_177473
Tmem191c
transmembrane protein 191C
chr15_+_85565935 14.744 NM_001113418
Ppara
peroxisome proliferator activated receptor alpha
chr15_+_79921725 14.711 NM_009303
NM_207708
Syngr1

synaptogyrin 1

chr7_+_17530050 14.586 Pnmal2
PNMA-like 2
chr14_-_21613162 14.507 NM_001039138
NM_001039139
NM_178597
Camk2g


calcium/calmodulin-dependent protein kinase II gamma


chr2_+_143371807 14.393 NM_008792
Pcsk2
proprotein convertase subtilisin/kexin type 2
chr7_-_133606617 14.139 Atp2a1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr9_-_121766670 14.053 Higd1a
HIG1 domain family, member 1A
chrX_-_68745773 14.052 NM_138309
Cd99l2
CD99 antigen-like 2
chr13_+_83803830 13.870 Mef2c
myocyte enhancer factor 2C
chr1_-_75274890 13.744 Resp18
regulated endocrine-specific protein 18
chr1_-_133964541 13.627 NM_001114662
NM_172510
Mfsd4

major facilitator superfamily domain containing 4

chr1_+_34858612 13.535 Arhgef4
Rho guanine nucleotide exchange factor (GEF) 4
chr11_-_63892874 13.309 NM_178379
Cox10
COX10 homolog, cytochrome c oxidase assembly protein, heme A: farnesyltransferase (yeast)
chr5_-_130363128 13.259 Chchd2
coiled-coil-helix-coiled-coil-helix domain containing 2
chr17_-_25922419 13.254 Haghl
hydroxyacylglutathione hydrolase-like
chr2_-_73749317 12.940 NM_175015
Atp5g3
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)
chr9_-_69989285 12.867 NM_029784
Fam81a
family with sequence similarity 81, member A
chr5_-_23950969 12.776 NM_023229
Fastk
Fas-activated serine/threonine kinase
chr15_+_85566055 12.623 Ppara
peroxisome proliferator activated receptor alpha
chr18_-_61173753 12.611 NM_201353
Slc6a7
solute carrier family 6 (neurotransmitter transporter, L-proline), member 7
chr19_-_37281951 12.606 Cpeb3
cytoplasmic polyadenylation element binding protein 3
chr12_-_17183693 12.532 NM_201531
Kcnf1
potassium voltage-gated channel, subfamily F, member 1
chr7_-_56099011 12.506 NM_013808
Csrp3
cysteine and glycine-rich protein 3
chr2_+_32251776 12.292 Ptges2
prostaglandin E synthase 2
chr7_-_133606586 12.198 NM_007504
Atp2a1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr9_+_43901941 12.092 Usp2
ubiquitin specific peptidase 2
chr4_-_8166157 12.049 Car8
carbonic anhydrase 8
chr2_-_102913613 11.948 NM_175094
Pdhx
pyruvate dehydrogenase complex, component X
chr5_-_30481492 11.876 NM_178878
Hadha
hydroxyacyl-Coenzyme A dehydrogenase/3-ketoacyl-Coenzyme A thiolase/enoyl-Coenzyme A hydratase (trifunctional protein), alpha subunit
chr4_-_117881591 11.819 Ptprf
protein tyrosine phosphatase, receptor type, F
chr4_+_155590035 11.800 NM_172417
2310042D19Rik
RIKEN cDNA 2310042D19 gene
chr5_-_134932407 11.788 NM_001081462
NM_001081463
NM_001081464
NM_001081466
NM_001081467
NM_001081468
NM_001081469
NM_001081470
NM_020331
Gtf2ird1








general transcription factor II I repeat domain-containing 1








chr1_+_78306890 11.720 NM_001004173
Sgpp2
sphingosine-1-phosphate phosphotase 2
chr5_+_130231000 11.704 Gbas
glioblastoma amplified sequence
chr11_-_73137838 11.672 Aspa
aspartoacylase
chr16_+_17276434 11.650 Tmem191c
transmembrane protein 191C
chr5_+_130230969 11.644 Gbas
glioblastoma amplified sequence
chr2_-_119488522 11.582 NM_027175
Ndufaf1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1
chr10_+_127631656 11.538 NM_001033264
Gls2
glutaminase 2 (liver, mitochondrial)
chr7_-_88851798 11.534 NM_001164086
NM_011983
Homer2

homer homolog 2 (Drosophila)

chr8_-_75877407 11.529 Large
like-glycosyltransferase
chr19_-_5085487 11.375 Tmem151a
transmembrane protein 151A
chr11_-_116060026 11.164 Acox1
acyl-Coenzyme A oxidase 1, palmitoyl
chr19_+_10271150 11.149 Fads1
fatty acid desaturase 1
chr7_+_17529961 11.121 NM_001099636
Pnmal2
PNMA-like 2
chr9_-_35018470 11.082 NM_172291
Foxred1
FAD-dependent oxidoreductase domain containing 1
chr7_-_31699850 11.060 NM_010758
Mag
myelin-associated glycoprotein
chr3_-_51212856 11.052 NM_025523
Ndufc1
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1
chr15_-_35867898 11.003 NM_053071
Cox6c
cytochrome c oxidase, subunit VIc
chr5_+_130231003 10.937 Gbas
glioblastoma amplified sequence
chr17_-_85189893 10.899 Lrpprc
leucine-rich PPR-motif containing
chr1_-_137210293 10.865 NM_011590
Timm17a
translocase of inner mitochondrial membrane 17a
chr13_-_74487687 10.840 NM_023281
Sdha
succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
chr5_+_130230890 10.676 NM_008095
Gbas
glioblastoma amplified sequence
chr7_-_134195490 10.645 NM_026918
Zg16
zymogen granule protein 16
chr11_-_32109606 10.624


chr6_+_39542563 10.588 NM_026612
Ndufb2
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr6_+_38613031 10.576 NM_001101507
Clec2l
C-type lectin domain family, member L
chr8_+_11448095 10.555 Col4a2
collagen, type IV, alpha 2
chr5_+_23899973 10.541 NM_029020
Abcb8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr10_-_88720534 10.413 NM_178773
Ano4
anoctamin 4
chr9_+_74918979 10.409 NM_010864
Myo5a
myosin VA
chr17_-_25922267 10.369 NM_026897
Haghl
hydroxyacylglutathione hydrolase-like
chr2_-_73749080 10.341 Atp5g3
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)
chr7_+_96781228 10.338 Me3
malic enzyme 3, NADP(+)-dependent, mitochondrial
chr12_-_16596573 10.312 NM_001130412
NM_015763
NM_172950
Lpin1


lipin 1


chr12_-_16596567 10.303 Lpin1
lipin 1
chr6_+_83087016 10.259 NM_009106
NM_133641
Rtkn

rhotekin

chr6_+_115085096 10.238 Syn2
synapsin II
chr9_-_57315800 10.186 NM_020270
Scamp5
secretory carrier membrane protein 5
chr15_-_35867884 10.167 Cox6c
cytochrome c oxidase, subunit VIc
chr12_-_16596537 10.145 Lpin1
lipin 1
chr11_+_3889935 10.025 NM_001177691
Gal3st1
galactose-3-O-sulfotransferase 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
4.71 6.33e-16 GO:0006091 generation of precursor metabolites and energy
1.83 3.67e-15 GO:0006810 transport
1.80 2.33e-14 GO:0051234 establishment of localization
1.68 9.18e-13 GO:0051179 localization
5.71 1.77e-10 GO:0022900 electron transport chain
2.32 1.84e-08 GO:0055114 oxidation-reduction process
2.28 2.02e-08 GO:0006811 ion transport
1.85 2.08e-08 GO:0044281 small molecule metabolic process
2.45 2.83e-08 GO:0042180 cellular ketone metabolic process
2.49 6.15e-08 GO:0006812 cation transport
2.40 1.92e-07 GO:0019752 carboxylic acid metabolic process
2.40 1.92e-07 GO:0043436 oxoacid metabolic process
2.35 5.03e-07 GO:0006082 organic acid metabolic process
13.92 2.71e-05 GO:0015985 energy coupled proton transport, down electrochemical gradient
13.92 2.71e-05 GO:0015986 ATP synthesis coupled proton transport
2.08 7.21e-05 GO:0055085 transmembrane transport
4.15 1.03e-04 GO:0015980 energy derivation by oxidation of organic compounds
2.68 1.41e-04 GO:0032787 monocarboxylic acid metabolic process
6.79 1.67e-04 GO:0006084 acetyl-CoA metabolic process
2.62 3.63e-04 GO:0015672 monovalent inorganic cation transport
2.95 5.61e-04 GO:0051186 cofactor metabolic process
5.11 7.15e-04 GO:0045333 cellular respiration
3.42 1.47e-03 GO:0007005 mitochondrion organization
5.16 1.64e-03 GO:0006754 ATP biosynthetic process
8.62 3.13e-03 GO:0046356 acetyl-CoA catabolic process
3.06 3.24e-03 GO:0006732 coenzyme metabolic process
2.08 3.26e-03 GO:0019725 cellular homeostasis
7.27 3.64e-03 GO:0009109 coenzyme catabolic process
2.13 3.91e-03 GO:0044282 small molecule catabolic process
1.21 3.94e-03 GO:0008152 metabolic process
2.15 6.86e-03 GO:0044283 small molecule biosynthetic process
2.17 7.36e-03 GO:0006873 cellular ion homeostasis
2.07 7.99e-03 GO:0030001 metal ion transport
1.63 9.58e-03 GO:0009056 catabolic process
4.39 1.13e-02 GO:0009206 purine ribonucleoside triphosphate biosynthetic process
2.08 1.17e-02 GO:0050801 ion homeostasis
2.31 1.31e-02 GO:0044271 cellular nitrogen compound biosynthetic process
4.33 1.34e-02 GO:0009145 purine nucleoside triphosphate biosynthetic process
4.33 1.34e-02 GO:0009201 ribonucleoside triphosphate biosynthetic process
2.11 1.37e-02 GO:0055082 cellular chemical homeostasis
2.61 1.39e-02 GO:0006631 fatty acid metabolic process
7.24 1.42e-02 GO:0009060 aerobic respiration
6.17 1.66e-02 GO:0051187 cofactor catabolic process
4.20 1.87e-02 GO:0009142 nucleoside triphosphate biosynthetic process
4.38 2.63e-02 GO:0015992 proton transport
7.92 2.74e-02 GO:0006099 tricarboxylic acid cycle
1.76 2.81e-02 GO:0006629 lipid metabolic process
4.70 2.98e-02 GO:0006839 mitochondrial transport
4.31 3.12e-02 GO:0006818 hydrogen transport
2.22 4.02e-02 GO:0019226 transmission of nerve impulse
2.22 4.02e-02 GO:0035637 multicellular organismal signaling
5.50 4.58e-02 GO:0031110 regulation of microtubule polymerization or depolymerization

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
3.15 3.62e-48 GO:0005739 mitochondrion
1.80 1.64e-39 GO:0044444 cytoplasmic part
4.07 2.88e-30 GO:0044429 mitochondrial part
4.51 1.75e-28 GO:0031966 mitochondrial membrane
4.38 7.37e-28 GO:0005740 mitochondrial envelope
4.90 7.28e-26 GO:0005743 mitochondrial inner membrane
1.47 1.37e-25 GO:0005737 cytoplasm
4.65 2.00e-24 GO:0019866 organelle inner membrane
2.53 9.96e-21 GO:0031090 organelle membrane
3.24 2.30e-20 GO:0031975 envelope
3.25 3.27e-20 GO:0031967 organelle envelope
6.37 1.56e-13 GO:0044455 mitochondrial membrane part
1.25 3.07e-13 GO:0005622 intracellular
1.25 4.89e-13 GO:0044424 intracellular part
8.64 1.81e-12 GO:0070469 respiratory chain
1.29 5.40e-12 GO:0043229 intracellular organelle
1.32 8.02e-12 GO:0043231 intracellular membrane-bounded organelle
1.28 9.71e-12 GO:0043226 organelle
1.31 1.18e-11 GO:0043227 membrane-bounded organelle
7.70 2.43e-08 GO:0005746 mitochondrial respiratory chain
3.99 2.18e-07 GO:0005759 mitochondrial matrix
1.24 3.82e-06 GO:0016020 membrane
1.11 5.01e-06 GO:0005623 cell
1.11 5.01e-06 GO:0044464 cell part
12.06 2.18e-05 GO:0045259 proton-transporting ATP synthase complex
1.36 3.05e-05 GO:0044422 organelle part
13.20 6.65e-05 GO:0005753 mitochondrial proton-transporting ATP synthase complex
6.91 8.14e-05 GO:0005747 mitochondrial respiratory chain complex I
6.91 8.14e-05 GO:0030964 NADH dehydrogenase complex
6.91 8.14e-05 GO:0045271 respiratory chain complex I
2.18 1.97e-04 GO:0045202 synapse
1.32 6.06e-04 GO:0044446 intracellular organelle part
2.00 1.09e-03 GO:0043005 neuron projection
1.68 6.20e-03 GO:0005794 Golgi apparatus
5.50 7.97e-03 GO:0016469 proton-transporting two-sector ATPase complex
1.59 8.32e-03 GO:0000267 cell fraction
1.61 9.16e-03 GO:0042995 cell projection
15.08 1.68e-02 GO:0045261 proton-transporting ATP synthase complex, catalytic core F(1)
4.85 2.34e-02 GO:0000313 organellar ribosome
4.85 2.34e-02 GO:0005761 mitochondrial ribosome
2.11 2.55e-02 GO:0044456 synapse part
2.19 2.80e-02 GO:0044431 Golgi apparatus part
2.26 2.95e-02 GO:0030424 axon

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
2.24 2.98e-09 GO:0022857 transmembrane transporter activity
2.30 5.43e-09 GO:0022891 substrate-specific transmembrane transporter activity
2.19 7.38e-09 GO:0022892 substrate-specific transporter activity
2.07 9.77e-09 GO:0005215 transporter activity
2.37 1.96e-08 GO:0015075 ion transmembrane transporter activity
1.38 9.30e-08 GO:0003824 catalytic activity
2.50 4.52e-07 GO:0008324 cation transmembrane transporter activity
2.11 8.23e-06 GO:0016491 oxidoreductase activity
3.23 2.26e-05 GO:0022890 inorganic cation transmembrane transporter activity
4.64 1.28e-04 GO:0015078 hydrogen ion transmembrane transporter activity
3.39 2.77e-04 GO:0015077 monovalent inorganic cation transmembrane transporter activity
2.66 5.67e-04 GO:0048037 cofactor binding
5.22 1.10e-03 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
22.62 2.01e-03 GO:0000104 succinate dehydrogenase activity
22.62 2.01e-03 GO:0004111 creatine kinase activity
2.77 8.26e-03 GO:0050662 coenzyme binding
1.41 1.69e-02 GO:0000166 nucleotide binding
2.11 1.94e-02 GO:0005216 ion channel activity
2.06 2.99e-02 GO:0022838 substrate-specific channel activity
5.66 3.05e-02 GO:0035254 glutamate receptor binding
7.54 4.57e-02 GO:0000062 fatty-acyl-CoA binding