Motif ID: EVI1.p2

Z-value: 1.425


Transcription factors associated with EVI1.p2:

Gene SymbolEntrez IDGene Name
Mecom 14013 MDS1 and EVI1 complex locus

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mecomchr3_-_304084080.191.1e-02Click!


Activity profile for motif EVI1.p2.

activity profile for motif EVI1.p2


Sorted Z-values histogram for motif EVI1.p2

Sorted Z-values for motif EVI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of EVI1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_134439804 44.396 NM_008400
Itgal
integrin alpha L
chr10_-_111434231 18.413 Glipr1
GLI pathogenesis-related 1 (glioma)
chr2_-_58012447 18.139 NM_139200
Cytip
cytohesin 1 interacting protein
chr10_-_111434265 17.862 NM_028608
Glipr1
GLI pathogenesis-related 1 (glioma)
chr6_+_48626133 16.196 NM_174960
Gimap9
GTPase, IMAP family member 9
chr4_-_60675161 14.638 NM_001164526
NM_001134644
NM_001045550
NM_008647
Mup10
Mup11
LOC100048885
Mup19
Mup1
Mup2

major urinary protein 10
major urinary protein 11
major urinary protein LOC100048885
major urinary protein 19
major urinary protein 1
major urinary protein 2

chr1_-_175465858 14.478 BC094916
cDNA sequence BC094916
chr11_-_82834223 14.047 NM_001167743
NM_181545
Slfn8

schlafen 8

chr5_-_88956788 13.477 NM_152839
Igj
immunoglobulin joining chain
chr4_-_60083171 13.401 Mup7
Mup1
major urinary protein 7
major urinary protein 1
chr4_-_61179982 13.392 Mup1
major urinary protein 1
chr4_-_60594469 13.249 Mup1
major urinary protein 1
chr4_-_60594496 13.015 Mup1
major urinary protein 1
chr5_-_138299171 12.636 NM_133209
Pilrb1
paired immunoglobin-like type 2 receptor beta 1
chr17_-_32557916 12.503 NM_021319
Pglyrp2
peptidoglycan recognition protein 2
chr4_-_61335031 11.994 Mup10
LOC100048884
Mup19
Mup1
Mup2
major urinary protein 10
novel member of the major urinary protein (Mup) gene family
major urinary protein 19
major urinary protein 1
major urinary protein 2
chr2_+_103809709 11.655 NM_001142336
Lmo2
LIM domain only 2
chr4_-_60434715 11.553 NM_001126319
Mup9
Mup10
LOC100048884
Mup19
Mup1
Mup2
major urinary protein 9
major urinary protein 10
novel member of the major urinary protein (Mup) gene family
major urinary protein 19
major urinary protein 1
major urinary protein 2
chr17_-_32557807 11.403 Pglyrp2
peptidoglycan recognition protein 2
chr5_+_34868420 11.180 NM_011893
Sh3bp2
SH3-domain binding protein 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 14 of 14 entries
Enrichment   P-value GO Accession GO Term
7.83 1.01e-03 GO:0035456 response to interferon-beta
7.83 1.01e-03 GO:0035458 cellular response to interferon-beta
5.10 2.78e-02 GO:0006805 xenobiotic metabolic process
5.10 2.78e-02 GO:0071466 cellular response to xenobiotic stimulus
5.08 1.05e-02 GO:0009410 response to xenobiotic stimulus
3.01 1.42e-03 GO:0050670 regulation of lymphocyte proliferation
2.98 1.66e-03 GO:0032944 regulation of mononuclear cell proliferation
2.93 2.27e-03 GO:0070663 regulation of leukocyte proliferation
2.29 2.26e-02 GO:0051249 regulation of lymphocyte activation
2.22 1.00e-02 GO:0050778 positive regulation of immune response
2.17 3.88e-02 GO:0002694 regulation of leukocyte activation
2.03 2.64e-03 GO:0006955 immune response
1.92 1.72e-02 GO:0002684 positive regulation of immune system process
1.81 3.31e-06 GO:0002376 immune system process

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
9.24 2.30e-02 GO:0042101 T cell receptor complex
1.74 2.21e-04 GO:0005615 extracellular space
1.60 6.43e-04 GO:0044421 extracellular region part
1.47 5.88e-05 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 2 of 2 entries
Enrichment   P-value GO Accession GO Term
5.14 4.50e-02 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NADH or NADPH as one donor, and incorporation of one atom of oxygen
2.64 8.90e-03 GO:0004497 monooxygenase activity