Motif ID: FEV.p2

Z-value: 2.872


Transcription factors associated with FEV.p2:

Gene SymbolEntrez IDGene Name
Fev 260298 FEV (ETS oncogene family)

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fevchr1_-_74931895-0.027.5e-01Click!


Activity profile for motif FEV.p2.

activity profile for motif FEV.p2


Sorted Z-values histogram for motif FEV.p2

Sorted Z-values for motif FEV.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FEV.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_140071818 52.296 NM_001111316
NM_011210
 Ptprc

protein tyrosine phosphatase, receptor type, C

chr12_-_32893074 48.741 NM_001146201
NM_020272
NM_001146200
 Pik3cg


phosphoinositide-3-kinase, catalytic, gamma polypeptide


chr16_+_36935029 48.285 NM_008225
 Hcls1
hematopoietic cell specific Lyn substrate 1
chr17_+_34726750 45.211 NM_134116
 Gpsm3
G-protein signalling modulator 3 (AGS3-like, C. elegans)
chr6_-_136889984 44.145 Arhgdib
Rho, GDP dissociation inhibitor (GDI) beta
chr14_+_75576599 43.386 Lcp1
lymphocyte cytosolic protein 1
chr17_+_34727032 42.010 Gpsm3
G-protein signalling modulator 3 (AGS3-like, C. elegans)
chr16_-_19983049 40.609 NM_183390
 Klhl6
kelch-like 6 (Drosophila)
chr15_+_78075220 39.981 NM_008677
 Ncf4
neutrophil cytosolic factor 4
chrX_-_98463514 39.767 NM_013563
 Il2rg
interleukin 2 receptor, gamma chain
chr11_-_83462722 35.304 NM_011337
 Ccl3
chemokine (C-C motif) ligand 3
chr7_-_52494453 34.614 Cd37
CD37 antigen
chr9_-_123883223 33.858 Ccr1
chemokine (C-C motif) receptor 1
chrX_+_45499599 32.852 NM_028773
 Sash3
SAM and SH3 domain containing 3
chr9_+_107885355 32.330 NM_177090
 Cdh29
Uba7
cadherin-like 29
ubiquitin-like modifier activating enzyme 7
chr11_-_69479553 32.025 NM_009853
 Cd68
CD68 antigen
chr4_-_63064369 32.021 NM_001045514
 Akna
AT-hook transcription factor
chr1_-_133173495 31.909 Ikbke
inhibitor of kappaB kinase epsilon
chr5_+_34886013 31.568 NM_001145858
 Sh3bp2
SH3-domain binding protein 2
chr2_+_90936845 31.304 NM_011355
 Sfpi1
SFFV proviral integration 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 229 entries
Enrichment   P-value GO Accession GO Term
3.09 3.72e-05 GO:0030888 regulation of B cell proliferation
3.02 8.32e-07 GO:0002768 immune response-regulating cell surface receptor signaling pathway
2.97 2.06e-04 GO:0007249 I-kappaB kinase/NF-kappaB cascade
2.96 1.19e-04 GO:0050851 antigen receptor-mediated signaling pathway
2.95 9.87e-03 GO:0001776 leukocyte homeostasis
2.95 1.72e-02 GO:0002260 lymphocyte homeostasis
2.95 1.72e-02 GO:0030890 positive regulation of B cell proliferation
2.89 2.28e-05 GO:0002429 immune response-activating cell surface receptor signaling pathway
2.79 3.33e-04 GO:0050871 positive regulation of B cell activation
2.72 2.61e-02 GO:0043409 negative regulation of MAPKKK cascade
2.67 1.37e-02 GO:0002687 positive regulation of leukocyte migration
2.57 6.38e-05 GO:0050864 regulation of B cell activation
2.56 3.29e-02 GO:0050729 positive regulation of inflammatory response
2.54 9.67e-03 GO:0002274 myeloid leukocyte activation
2.53 1.67e-02 GO:0042108 positive regulation of cytokine biosynthetic process
2.48 2.49e-02 GO:0032675 regulation of interleukin-6 production
2.45 2.14e-02 GO:0002263 cell activation involved in immune response
2.45 2.14e-02 GO:0002366 leukocyte activation involved in immune response
2.40 8.33e-09 GO:0002764 immune response-regulating signaling pathway
2.34 2.40e-04 GO:0006364 rRNA processing

Gene overrepresentation in compartment category:

Showing 1 to 20 of 44 entries
Enrichment   P-value GO Accession GO Term
5.58 1.88e-02 GO:0070761 pre-snoRNP complex
2.49 1.14e-02 GO:0022626 cytosolic ribosome
2.30 5.19e-04 GO:0071013 catalytic step 2 spliceosome
2.21 1.77e-06 GO:0005681 spliceosomal complex
2.17 5.27e-05 GO:0044445 cytosolic part
2.17 2.56e-03 GO:0030027 lamellipodium
2.02 3.88e-06 GO:0031252 cell leading edge
1.80 2.22e-11 GO:0030529 ribonucleoprotein complex
1.77 3.38e-04 GO:0009897 external side of plasma membrane
1.72 5.02e-07 GO:0005730 nucleolus
1.71 8.93e-03 GO:0005635 nuclear envelope
1.66 2.11e-11 GO:0044451 nucleoplasm part
1.64 1.26e-30 GO:0044428 nuclear part
1.64 2.74e-16 GO:0005654 nucleoplasm
1.62 2.10e-23 GO:0031981 nuclear lumen
1.61 9.22e-04 GO:0005667 transcription factor complex
1.58 9.25e-21 GO:0005829 cytosol
1.57 8.66e-03 GO:0015629 actin cytoskeleton
1.56 1.81e-22 GO:0043233 organelle lumen
1.56 2.24e-22 GO:0070013 intracellular organelle lumen

Gene overrepresentation in function category:

Showing 1 to 20 of 47 entries
Enrichment   P-value GO Accession GO Term
2.58 4.64e-02 GO:0042379 chemokine receptor binding
2.26 1.07e-03 GO:0005099 Ras GTPase activator activity
1.90 2.15e-05 GO:0005096 GTPase activator activity
1.73 3.09e-04 GO:0005083 small GTPase regulator activity
1.72 2.41e-05 GO:0008047 enzyme activator activity
1.71 1.97e-02 GO:0004842 ubiquitin-protein ligase activity
1.70 1.19e-02 GO:0019787 small conjugating protein ligase activity
1.68 1.67e-02 GO:0043566 structure-specific DNA binding
1.65 1.02e-05 GO:0030695 GTPase regulator activity
1.64 4.89e-02 GO:0010843 promoter binding
1.62 4.90e-02 GO:0000975 regulatory region DNA binding
1.62 4.90e-02 GO:0001067 regulatory region nucleic acid binding
1.62 4.90e-02 GO:0044212 transcription regulatory region DNA binding
1.61 3.33e-05 GO:0060589 nucleoside-triphosphatase regulator activity
1.60 1.31e-09 GO:0003723 RNA binding
1.60 1.73e-02 GO:0019901 protein kinase binding
1.55 9.53e-03 GO:0016564 transcription repressor activity
1.54 8.51e-03 GO:0016563 transcription activator activity
1.53 3.27e-02 GO:0019900 kinase binding
1.50 5.56e-07 GO:0001071 nucleic acid binding transcription factor activity