Motif ID: FOSL2.p2

Z-value: 1.492


Transcription factors associated with FOSL2.p2:

Gene SymbolEntrez IDGene Name
Fosl2 14284 fos-like antigen 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Fosl2chr5_+_324382190.298.3e-05Click!


Activity profile for motif FOSL2.p2.

activity profile for motif FOSL2.p2


Sorted Z-values histogram for motif FOSL2.p2

Sorted Z-values for motif FOSL2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOSL2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr19_+_5637712 31.362 Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr7_+_135273060 30.352 NM_021334
 Itgax
integrin alpha X
chr7_+_133728451 29.840 Apobr
apolipoprotein B receptor
chr1_+_175560938 26.821 NM_175026
 Pyhin1
pyrin and HIN domain family, member 1
chr5_-_135422730 26.029 Cldn4
claudin 4
chr7_+_133728483 25.539 NM_138310
 Apobr
apolipoprotein B receptor
chr5_-_135422780 24.154 Cldn4
claudin 4
chr19_+_5637741 23.631 Rela
v-rel reticuloendotheliosis viral oncogene homolog A (avian)
chr1_+_175561105 23.200 Pyhin1
pyrin and HIN domain family, member 1
chr11_-_69479553 22.095 NM_009853
 Cd68
CD68 antigen
chr6_+_48986501 21.486 NM_053110
 Gpnmb
glycoprotein (transmembrane) nmb
chr5_-_135422795 20.836 NM_009903
 Cldn4
claudin 4
chr2_-_34813680 19.744 Traf1
TNF receptor-associated factor 1
chr2_-_34813633 19.297 Traf1
TNF receptor-associated factor 1
chr14_+_79915429 19.142 Elf1
E74-like factor 1
chr17_+_45692647 18.782 NM_008690
 Nfkbie
nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, epsilon
chr7_-_53176218 18.514 NM_001146346
 Emp3
epithelial membrane protein 3
chr7_-_53176582 17.411 NM_010129
 Emp3
epithelial membrane protein 3
chr7_+_86058817 16.859 Isg20
interferon-stimulated protein
chr16_+_36935029 16.809 NM_008225
 Hcls1
hematopoietic cell specific Lyn substrate 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 65 entries
Enrichment   P-value GO Accession GO Term
4.45 2.23e-02 GO:0071222 cellular response to lipopolysaccharide
3.93 4.20e-02 GO:0050871 positive regulation of B cell activation
3.87 2.40e-02 GO:0051092 positive regulation of NF-kappaB transcription factor activity
3.61 5.60e-04 GO:0032496 response to lipopolysaccharide
3.52 4.60e-04 GO:0051091 positive regulation of sequence-specific DNA binding transcription factor activity
3.35 6.27e-04 GO:0002237 response to molecule of bacterial origin
3.35 1.11e-03 GO:0090047 positive regulation of transcription regulator activity
3.19 1.69e-04 GO:0001819 positive regulation of cytokine production
3.07 5.45e-03 GO:0043388 positive regulation of DNA binding
3.03 8.63e-04 GO:0051251 positive regulation of lymphocyte activation
2.84 8.11e-03 GO:0071345 cellular response to cytokine stimulus
2.83 5.27e-03 GO:0002764 immune response-regulating signaling pathway
2.79 2.88e-03 GO:0050867 positive regulation of cell activation
2.79 4.44e-03 GO:0002696 positive regulation of leukocyte activation
2.73 8.67e-05 GO:0051090 regulation of sequence-specific DNA binding transcription factor activity
2.68 3.34e-04 GO:0051249 regulation of lymphocyte activation
2.68 3.42e-02 GO:0002757 immune response-activating signal transduction
2.67 1.59e-04 GO:0090046 regulation of transcription regulator activity
2.65 2.81e-02 GO:0051099 positive regulation of binding
2.57 5.83e-05 GO:0001817 regulation of cytokine production

Gene overrepresentation in compartment category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
1.68 3.25e-03 GO:0005615 extracellular space
1.59 2.77e-03 GO:0044421 extracellular region part
1.45 3.77e-04 GO:0005576 extracellular region
1.24 2.62e-02 GO:0005886 plasma membrane
1.23 4.40e-02 GO:0071944 cell periphery

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
Enrichment   P-value GO Accession GO Term
3.41 2.04e-03 GO:0070851 growth factor receptor binding
2.94 1.81e-02 GO:0019955 cytokine binding
2.72 4.39e-04 GO:0005126 cytokine receptor binding
1.67 1.10e-04 GO:0005102 receptor binding
1.60 2.62e-02 GO:0001071 nucleic acid binding transcription factor activity
1.60 2.62e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.31 1.41e-08 GO:0005515 protein binding
1.17 3.00e-07 GO:0005488 binding