Motif ID: FOX{F1,F2,J1}.p2

Z-value: 2.159


Transcription factors associated with FOX{F1,F2,J1}.p2:

Gene SymbolEntrez IDGene Name
Foxf1a 15227 forkhead box F1a
Foxf2 14238 forkhead box F2
Foxj1 15223 forkhead box J1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxf1achr8_+_1236082520.172.1e-02Click!
Foxf2chr13_+_317176030.082.9e-01Click!
Foxj1chr11_-_1161976940.064.0e-01Click!


Activity profile for motif FOX{F1,F2,J1}.p2.

activity profile for motif FOX{F1,F2,J1}.p2


Sorted Z-values histogram for motif FOX{F1,F2,J1}.p2

Sorted Z-values for motif FOX{F1,F2,J1}.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOX{F1,F2,J1}.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_104542598 113.295 Sparcl1
SPARC-like 1
chr5_-_104542751 91.210 Sparcl1
SPARC-like 1
chr5_-_104542729 90.794 Sparcl1
SPARC-like 1
chr5_-_104542641 88.504 Sparcl1
SPARC-like 1
chr15_+_91958558 74.364 NM_007727
Cntn1
contactin 1
chr16_-_34263047 61.502 Kalrn
kalirin, RhoGEF kinase
chr16_-_34263272 59.566 Kalrn
kalirin, RhoGEF kinase
chr14_-_52533114 56.817 NM_001145959
NM_013864
Ndrg2

N-myc downstream regulated gene 2

chr14_-_52533039 56.605 Ndrg2
N-myc downstream regulated gene 2
chr14_-_52532988 53.878 Ndrg2
N-myc downstream regulated gene 2
chr1_-_89470442 45.015 NM_001111314
Ngef
neuronal guanine nucleotide exchange factor
chr5_+_89012596 41.641 NM_027530
Rufy3
RUN and FYVE domain containing 3
chr12_-_85791928 37.865 Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr17_-_85461840 37.247 Prepl
prolyl endopeptidase-like
chr7_-_107805365 37.235 Plekhb1
pleckstrin homology domain containing, family B (evectins) member 1
chr5_+_89012537 37.007 Rufy3
RUN and FYVE domain containing 3
chr15_+_91991704 35.451 NM_001159647
Cntn1
contactin 1
chr2_+_71892681 33.985 Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr14_+_28689289 33.481 Erc2
ELKS/RAB6-interacting/CAST family member 2
chr12_-_85791897 33.281 NM_134042
Aldh6a1
aldehyde dehydrogenase family 6, subfamily A1
chr7_+_31076771 31.559 NM_001081114
Clip3
CAP-GLY domain containing linker protein 3
chr18_-_39078304 31.524 NM_010197
Fgf1
fibroblast growth factor 1
chr16_+_5885447 30.909 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr5_+_89012547 30.492 Rufy3
RUN and FYVE domain containing 3
chr15_-_88808967 30.225 NM_133241
Mlc1
megalencephalic leukoencephalopathy with subcortical cysts 1 homolog (human)
chr4_+_101180625 29.786 Dnajc6
DnaJ (Hsp40) homolog, subfamily C, member 6
chr2_+_20211539 29.099 NM_001081006
Etl4
enhancer trap locus 4
chr3_+_7366586 27.616 NM_008862
Pkia
protein kinase inhibitor, alpha
chr7_+_31076852 27.255 Clip3
CAP-GLY domain containing linker protein 3
chr13_+_59234737 26.264 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr14_-_71029960 26.161 NM_013514
Epb4.9
erythrocyte protein band 4.9
chr15_+_3220766 25.875 NM_001042613
NM_001042614
NM_009155
Sepp1


selenoprotein P, plasma, 1


chr2_+_73150702 24.570 NM_029022
Scrn3
secernin 3
chr5_-_53499398 24.520 Sel1l3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr4_-_117881591 24.366 Ptprf
protein tyrosine phosphatase, receptor type, F
chr8_+_46744023 24.198 Sorbs2
sorbin and SH3 domain containing 2
chr2_+_121184334 23.966 NM_009897
Ckmt1
creatine kinase, mitochondrial 1, ubiquitous
chr5_-_71233855 23.530 NM_010252
Gabrg1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr12_+_71008808 23.510 Atl1
atlastin GTPase 1
chr18_+_37089837 23.453 NM_054072
Pcdha1
protocadherin alpha 1
chrX_-_149078963 23.345 Shroom2
shroom family member 2
chr1_+_34068669 23.184 NM_133833
NM_134448
Dst

dystonin

chr18_+_37152024 22.888 NM_201243
Pcdha8
protocadherin alpha 8
chr15_+_3220994 22.710 Sepp1
selenoprotein P, plasma, 1
chr1_+_7162595 22.640 Pcmtd1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 1
chr1_+_34356614 22.355 Dst
dystonin
chr10_+_111708176 21.637 NM_001025581
Kcnc2
potassium voltage gated channel, Shaw-related subfamily, member 2
chr5_-_104543106 21.631 NM_010097
Sparcl1
SPARC-like 1
chrX_+_7496899 21.426 NM_013892
Pcsk1n
proprotein convertase subtilisin/kexin type 1 inhibitor
chr19_-_38199737 21.420 NM_001159487
Rbp4
retinol binding protein 4, plasma
chr5_-_139606339 20.478 Prkar1b
protein kinase, cAMP dependent regulatory, type I beta
chr15_+_3220999 20.160 Sepp1
selenoprotein P, plasma, 1
chr5_+_90890764 19.560 Alb
albumin
chr5_-_122906470 19.437 Atp2a2
ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr18_+_37133455 19.335 NM_009957
Pcdha7
protocadherin alpha 7
chr12_-_113749363 18.979 NM_178915
Tmem179
transmembrane protein 179
chr10_+_5151833 18.683 NM_001079686
Syne1
synaptic nuclear envelope 1
chr1_+_9591492 18.418 3110035E14Rik
RIKEN cDNA 3110035E14 gene
chr7_+_137720997 18.316 NM_001004468
NM_206856
Tacc2

transforming, acidic coiled-coil containing protein 2

chr3_+_62142698 18.130 NM_001081295
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr13_+_97837240 17.946 NM_001146045
Fam169a
family with sequence similarity 169, member A
chr1_+_21208679 17.712 NM_029398
Tmem14a
transmembrane protein 14A
chr19_-_58529766 17.656 Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr9_+_47338431 17.388 NM_001025600
NM_018770
NM_207675
NM_207676
Cadm1



cell adhesion molecule 1



chr18_+_23468655 17.388 Dtna
dystrobrevin alpha
chrX_-_72823561 17.337 Rab39b
RAB39B, member RAS oncogene family
chr9_+_47338255 17.150 Cadm1
cell adhesion molecule 1
chrX_+_7299358 16.877 NM_172372
Wdr45
WD repeat domain 45
chr6_-_148392841 16.817 NM_198967
Tmtc1
transmembrane and tetratricopeptide repeat containing 1
chr6_+_129483238 16.755 Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr13_+_109444370 16.714 NM_011056
Pde4d
phosphodiesterase 4D, cAMP specific
chr6_+_129483295 16.668 Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr2_-_73498303 16.461 NM_001166604
NM_175752
Chn1

chimerin (chimaerin) 1

chr4_+_101180580 16.244 NM_001164584
NM_001164585
Dnajc6

DnaJ (Hsp40) homolog, subfamily C, member 6

chr9_-_49311823 16.227 Ncam1
neural cell adhesion molecule 1
chr1_-_134603848 15.948 NM_001160318
Nfasc
neurofascin
chr16_+_29209780 15.573 NM_013751
Hrasls
HRAS-like suppressor
chr1_-_173126368 15.566 NM_025557
Pcp4l1
Purkinje cell protein 4-like 1
chr7_-_107805466 15.562 NM_001163186
NM_001163187
Plekhb1

pleckstrin homology domain containing, family B (evectins) member 1

chrX_+_7299332 15.447 Wdr45
WD repeat domain 45
chr15_-_66801093 15.396 Ndrg1
N-myc downstream regulated gene 1
chr12_+_85792371 15.204 NM_173756
Lin52
lin-52 homolog (C. elegans)
chr11_+_78137699 14.948 NM_009657
Aldoc
aldolase C, fructose-bisphosphate
chr19_-_4012698 14.923 NM_133666
Ndufv1
NADH dehydrogenase (ubiquinone) flavoprotein 1
chr19_-_4012654 14.862 Ndufv1
NADH dehydrogenase (ubiquinone) flavoprotein 1
chr1_+_173155414 14.849 Apoa2
apolipoprotein A-II
chr14_+_120674921 14.636 Mbnl2
muscleblind-like 2
chr11_+_69435553 14.527 NM_026991
Sat2
spermidine/spermine N1-acetyl transferase 2
chr18_-_13021181 14.508 Osbpl1a
oxysterol binding protein-like 1A
chr14_+_120674939 14.488 Mbnl2
muscleblind-like 2
chr18_+_23468585 14.374 Dtna
dystrobrevin alpha
chr14_+_120674933 14.351 Mbnl2
muscleblind-like 2
chr10_+_28931448 14.349 NM_001162537
9330159F19Rik
RIKEN cDNA 9330159F19 gene
chr6_+_4853319 14.218 NM_181595
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr6_+_96063137 14.167 NM_182808
Fam19a1
family with sequence similarity 19, member A1
chr2_+_67955769 14.155 NM_020283
B3galt1
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr2_+_158201373 14.081 NM_175692
Snhg11
small nucleolar RNA host gene 11
chr9_-_102256962 13.949 NM_001168296
NM_173447
Ephb1

Eph receptor B1

chr14_+_112074336 13.907 NM_198865
Slitrk5
SLIT and NTRK-like family, member 5
chr5_-_103640272 13.886 NM_001081567
NM_009158
Mapk10

mitogen-activated protein kinase 10

chr18_+_37854011 13.857 NM_033588
Pcdhga5
protocadherin gamma subfamily A, 5
chr10_-_57252251 13.690 Serinc1
serine incorporator 1
chr18_+_37112301 13.681 NM_001174154
NM_007766
Pcdha4-g
Pcdha4
protocadherin alpha 4-gamma
protocadherin alpha 4
chr7_-_147268395 13.655 NM_001190385
NM_026769
Caly

calcyon neuron-specific vesicular protein

chr6_+_141472906 13.345 NM_001177772
NM_021471
Slco1c1

solute carrier organic anion transporter family, member 1c1

chr1_+_181476534 13.119 NM_146105
Cnst
consortin, connexin sorting protein
chr14_-_122097583 13.056 NM_001081039
Dock9
dedicator of cytokinesis 9
chr1_-_42749940 12.924 2610017I09Rik
RIKEN cDNA 2610017I09 gene
chr16_+_31422377 12.838 NM_175177
Bdh1
3-hydroxybutyrate dehydrogenase, type 1
chr12_+_110834872 12.751 1110006E14Rik
RIKEN cDNA 1110006E14 gene
chr10_+_122701051 12.675 NM_182807
Fam19a2
family with sequence similarity 19, member A2
chr1_+_133737686 12.584 Slc41a1
solute carrier family 41, member 1
chr14_+_69984344 12.480 Entpd4
ectonucleoside triphosphate diphosphohydrolase 4
chr14_+_120674913 12.457 Mbnl2
muscleblind-like 2
chr2_-_148701164 12.408 Cst3
cystatin C
chr15_-_66801198 12.367 NM_008681
Ndrg1
N-myc downstream regulated gene 1
chr1_+_169548381 12.344 NM_001159731
Rxrg
retinoid X receptor gamma
chr5_+_89012600 12.301 Rufy3
RUN and FYVE domain containing 3
chr15_+_88890519 12.050 Panx2
pannexin 2
chr7_+_52104591 11.944 NM_026270
Akt1s1
AKT1 substrate 1 (proline-rich)
chr6_-_113841356 11.908 NM_001036684
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr8_-_127093601 11.871 NM_007428
Agt
angiotensinogen (serpin peptidase inhibitor, clade A, member 8)
chr6_+_129483215 11.852 Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr6_+_22825464 11.837 NM_001081306
Ptprz1
protein tyrosine phosphatase, receptor type Z, polypeptide 1
chr11_+_31900378 11.787 NM_008741
Nsg2
neuron specific gene family member 2
chr15_+_99223377 11.786 NM_001171034
NM_001171036
NM_026669
Tmbim6


transmembrane BAX inhibitor motif containing 6


chr4_-_118162354 11.773 Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr2_-_127481868 11.717 Mal
myelin and lymphocyte protein, T-cell differentiation protein
chr18_-_12978106 11.601 Osbpl1a
oxysterol binding protein-like 1A
chr4_-_118162385 11.583 NM_011587
Tie1
tyrosine kinase with immunoglobulin-like and EGF-like domains 1
chr4_-_62815137 11.543 NM_007443
Ambp
alpha 1 microglobulin/bikunin
chr2_+_26828935 11.386 NM_001001322
Adamts13
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13
chr1_+_9591550 11.249 3110035E14Rik
RIKEN cDNA 3110035E14 gene
chr6_+_129483154 11.180 Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr9_-_107571294 11.159 Slc38a3
solute carrier family 38, member 3
chr13_-_111070225 11.052 Rab3c
RAB3C, member RAS oncogene family
chr10_+_94038001 10.985 NM_001168684
Tmcc3
transmembrane and coiled coil domains 3
chr3_-_97692613 10.950 NM_001039376
Pde4dip
phosphodiesterase 4D interacting protein (myomegalin)
chr6_-_60779848 10.950 NM_009221
Snca
synuclein, alpha
chr16_+_42955690 10.934 BC002163
NADH dehydrogenase Fe-S protein 5 pseudogene
chr2_-_71205805 10.927 Slc25a12
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr14_-_104243541 10.795 Ednrb
endothelin receptor type B
chr8_+_73051625 10.713 NM_001111066
NM_010223
Fkbp8

FK506 binding protein 8

chr7_-_125263314 10.653 Arl6ip1
ADP-ribosylation factor-like 6 interacting protein 1
chr15_-_63891810 10.597 NM_144846
Fam49b
family with sequence similarity 49, member B
chr7_+_148817700 10.536 Ap2a2
adaptor protein complex AP-2, alpha 2 subunit
chr10_-_57252252 10.399 NM_019760
Serinc1
serine incorporator 1
chr15_+_97942484 10.355 NM_021514
Pfkm
phosphofructokinase, muscle
chr6_+_49773596 10.275 Npy
neuropeptide Y
chr3_+_105916283 10.214 NM_023186
Chia
chitinase, acidic
chr9_-_107571304 10.201 Slc38a3
solute carrier family 38, member 3
chr8_-_87297283 10.200 Nfix
nuclear factor I/X
chr7_-_93924317 10.171 NM_001159706
NM_016770
Folh1

folate hydrolase

chr19_+_53403902 10.100 NM_010847
Mxi1
Max interacting protein 1
chr11_-_97372344 10.045 Srcin1
SRC kinase signaling inhibitor 1
chr7_-_26460180 9.971 NM_177102
Tmem91
transmembrane protein 91
chr2_-_91019477 9.915 NM_001177720
Madd
MAP-kinase activating death domain
chr9_-_73781373 9.897 NM_001081153
Unc13c
unc-13 homolog C (C. elegans)
chr14_-_94287950 9.887 NM_001081377
Pcdh9
protocadherin 9
chr19_-_29101759 9.880


chr1_-_182126032 9.774 NM_023341
Adck3
aarF domain containing kinase 3
chr8_+_73051648 9.725 Fkbp8
FK506 binding protein 8
chr12_+_105576693 9.674 NM_011458
Serpina3k
serine (or cysteine) peptidase inhibitor, clade A, member 3K
chr6_+_129483206 9.670 NM_020590
Gabarapl1
gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1
chr5_-_113709569 9.636 Sgsm1
small G protein signaling modulator 1
chr8_+_73051651 9.580 Fkbp8
FK506 binding protein 8
chr11_-_107209443 9.567 Pitpnc1
phosphatidylinositol transfer protein, cytoplasmic 1
chr17_+_75835208 9.435 NM_001166493
Rasgrp3
RAS, guanyl releasing protein 3
chr9_+_47338449 9.373 Cadm1
cell adhesion molecule 1
chr6_-_113841295 9.254 Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr12_+_105644917 9.216 NM_009252
Serpina3n
serine (or cysteine) peptidase inhibitor, clade A, member 3N
chr9_+_46036788 9.204 Apoa1
apolipoprotein A-I
chr7_+_107423813 9.171 Pgm2l1
phosphoglucomutase 2-like 1
chr15_+_99223622 9.069 NM_001171035
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr7_-_26460133 9.066 Tmem91
transmembrane protein 91
chr18_+_37844927 9.040 NM_033587
Pcdhga4
protocadherin gamma subfamily A, 4
chr1_-_94538517 8.984 NM_001163425
Myeov2
myeloma overexpressed 2
chr19_-_42160732 8.973 NM_198108
Morn4
MORN repeat containing 4
chr11_-_103733519 8.830 Nsf
N-ethylmaleimide sensitive fusion protein
chr17_+_24546733 8.733 Abca3
ATP-binding cassette, sub-family A (ABC1), member 3
chr3_-_146432922 8.713 Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr7_-_52104247 8.646 Tbc1d17
TBC1 domain family, member 17
chr5_-_138181225 8.595 NM_175521
6430598A04Rik
RIKEN cDNA 6430598A04 gene
chr11_+_69867869 8.551 NM_009714
Asgr1
asialoglycoprotein receptor 1
chr2_+_164311755 8.547 NM_026797
Dbndd2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr19_-_21467250 8.539 Gda
guanine deaminase
chr1_+_91351373 8.401 NM_001037136
NM_178119
Agap1

ArfGAP with GTPase domain, ankyrin repeat and PH domain 1

chr3_+_88373199 8.349 Ubqln4
ubiquilin 4
chr12_+_38607291 8.298 NM_178681
Dgkb
diacylglycerol kinase, beta
chr6_+_38484796 8.294 NM_025363
1110001J03Rik
RIKEN cDNA 1110001J03 gene
chr10_-_57252184 8.284 Serinc1
serine incorporator 1
chr1_-_170085798 8.230 Pbx1
pre B-cell leukemia transcription factor 1
chr1_-_174128558 8.217 Pea15a
phosphoprotein enriched in astrocytes 15A
chr8_-_47209499 8.045 NM_207213
Snx25
sorting nexin 25
chr8_+_96334879 8.029 Gnao1
guanine nucleotide binding protein, alpha O
chr2_-_32702729 8.027 NM_009295
NM_001113569
Stxbp1

syntaxin binding protein 1

chr11_+_16157685 7.953 NM_145967
Vstm2a
V-set and transmembrane domain containing 2A
chr16_+_7409879 7.927 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr7_-_52104448 7.814 NM_001042655
Tbc1d17
TBC1 domain family, member 17
chr9_+_46036799 7.772 Apoa1
apolipoprotein A-I

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.90 6.07e-05 GO:0032879 regulation of localization
1.44 1.56e-04 GO:0051179 localization
1.48 3.24e-04 GO:0051234 establishment of localization
1.45 1.32e-03 GO:0006810 transport
1.94 1.81e-03 GO:0051049 regulation of transport
2.36 3.54e-03 GO:0051050 positive regulation of transport
4.52 8.83e-03 GO:0043270 positive regulation of ion transport
5.82 1.03e-02 GO:0061041 regulation of wound healing
3.07 2.58e-02 GO:0050878 regulation of body fluid levels

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.35 2.69e-07 GO:0044444 cytoplasmic part
1.90 4.81e-07 GO:0000267 cell fraction
1.96 6.22e-06 GO:0005626 insoluble fraction
2.10 6.85e-06 GO:0005615 extracellular space
1.97 9.91e-06 GO:0005624 membrane fraction
1.39 4.86e-05 GO:0071944 cell periphery
1.22 8.62e-05 GO:0005737 cytoplasm
1.81 2.39e-04 GO:0044421 extracellular region part
1.36 3.42e-04 GO:0005886 plasma membrane
1.67 1.03e-03 GO:0031090 organelle membrane
1.68 8.61e-03 GO:0005794 Golgi apparatus
2.13 4.68e-02 GO:0005792 microsome

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
2.29 7.20e-04 GO:0008289 lipid binding
11.65 2.34e-03 GO:0015248 sterol transporter activity
11.65 2.34e-03 GO:0017127 cholesterol transporter activity
1.63 1.93e-02 GO:0005215 transporter activity
4.27 2.19e-02 GO:0005496 steroid binding
2.78 2.76e-02 GO:0004866 endopeptidase inhibitor activity
2.68 4.57e-02 GO:0061135 endopeptidase regulator activity