Motif ID: FOXL1.p2

Z-value: 1.606


Transcription factors associated with FOXL1.p2:

Gene SymbolEntrez IDGene Name
Foxl1 14241 forkhead box L1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Foxl1chr8_+_123651742-0.199.8e-03Click!


Activity profile for motif FOXL1.p2.

activity profile for motif FOXL1.p2


Sorted Z-values histogram for motif FOXL1.p2

Sorted Z-values for motif FOXL1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of FOXL1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr13_+_49704471 35.230 Ogn
osteoglycin
chr1_+_45402907 34.804 Col3a1
collagen, type III, alpha 1
chr10_+_97028134 29.635 NM_008524
 Lum
lumican
chr10_+_97028409 27.064 Lum
lumican
chr10_+_97028456 25.576 Lum
lumican
chr17_-_46155601 25.212 Vegfa
vascular endothelial growth factor A
chr7_-_125629996 24.952 Itpripl2
inositol 1,4,5-triphosphate receptor interacting protein-like 2
chr19_+_9092973 24.576 Ahnak
AHNAK nucleoprotein (desmoyokin)
chr6_-_14705104 23.724 NM_080464
 Ppp1r3a
protein phosphatase 1, regulatory (inhibitor) subunit 3A
chr6_+_4465627 22.035 Col1a2
collagen, type I, alpha 2
chr1_+_92100572 21.972 NM_007722
 Cxcr7
chemokine (C-X-C motif) receptor 7
chr16_+_45093784 21.497 Ccdc80
coiled-coil domain containing 80
chr14_+_102239673 21.398 Lmo7
LIM domain only 7
chr1_+_59543450 21.129


chr16_-_85862579 19.548 Adamts5
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
chr13_+_49639847 19.540 Aspn
asporin
chr13_+_49639799 18.274 NM_001172481
NM_025711
 Aspn

asporin

chr14_-_104213981 17.953


chr8_+_55635683 15.470 NM_029569
 Asb5
ankyrin repeat and SOCs box-containing 5
chr11_+_67013553 15.243 NM_030679
 Myh1
myosin, heavy polypeptide 1, skeletal muscle, adult

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 88 entries
Enrichment   P-value GO Accession GO Term
19.80 3.82e-02 GO:0043589 skin morphogenesis
12.15 3.72e-05 GO:0030239 myofibril assembly
11.88 1.16e-02 GO:0045214 sarcomere organization
10.24 4.13e-05 GO:0031032 actomyosin structure organization
7.65 8.49e-08 GO:0055002 striated muscle cell development
6.81 8.86e-04 GO:0048747 muscle fiber development
6.73 7.55e-07 GO:0055001 muscle cell development
6.73 3.04e-04 GO:0010906 regulation of glucose metabolic process
6.52 1.48e-02 GO:0035051 cardiac cell differentiation
6.42 5.38e-10 GO:0051146 striated muscle cell differentiation
6.16 3.31e-06 GO:0007519 skeletal muscle tissue development
5.94 5.94e-06 GO:0060538 skeletal muscle organ development
5.66 2.23e-03 GO:0010675 regulation of cellular carbohydrate metabolic process
5.57 2.67e-03 GO:0006109 regulation of carbohydrate metabolic process
5.55 8.51e-07 GO:0006936 muscle contraction
5.51 3.27e-10 GO:0042692 muscle cell differentiation
5.31 2.78e-07 GO:0003012 muscle system process
5.29 3.65e-10 GO:0060537 muscle tissue development
5.12 1.43e-08 GO:0014706 striated muscle tissue development
4.92 1.45e-08 GO:0007517 muscle organ development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 56 entries
Enrichment   P-value GO Accession GO Term
13.71 6.02e-04 GO:0005583 fibrillar collagen
9.90 2.91e-02 GO:0005865 striated muscle thin filament
9.90 2.91e-02 GO:0031672 A band
9.14 4.35e-04 GO:0005581 collagen
8.32 4.05e-03 GO:0031984 organelle subcompartment
7.43 9.14e-03 GO:0009925 basal plasma membrane
7.43 3.44e-02 GO:0031985 Golgi cisterna
6.78 7.86e-10 GO:0030017 sarcomere
6.47 2.04e-12 GO:0043292 contractile fiber
6.25 1.43e-10 GO:0030016 myofibril
6.22 1.49e-09 GO:0044449 contractile fiber part
6.12 3.48e-02 GO:0045178 basal part of cell
6.08 5.76e-07 GO:0042383 sarcolemma
6.05 4.46e-04 GO:0030018 Z disc
5.66 2.04e-02 GO:0016529 sarcoplasmic reticulum
5.48 4.53e-04 GO:0031674 I band
5.33 9.77e-08 GO:0044420 extracellular matrix part
5.17 4.01e-02 GO:0016528 sarcoplasm
5.12 6.37e-03 GO:0005901 caveola
4.86 2.52e-02 GO:0016459 myosin complex

Gene overrepresentation in function category:

Showing 1 to 12 of 12 entries
Enrichment   P-value GO Accession GO Term
10.24 8.75e-06 GO:0005200 structural constituent of cytoskeleton
8.49 2.24e-02 GO:0001968 fibronectin binding
5.38 8.75e-07 GO:0019838 growth factor binding
2.58 4.55e-06 GO:0008092 cytoskeletal protein binding
2.46 3.22e-02 GO:0046982 protein heterodimerization activity
2.39 3.46e-03 GO:0005198 structural molecule activity
2.38 3.83e-02 GO:0003779 actin binding
2.38 3.83e-02 GO:0019900 kinase binding
1.88 4.60e-03 GO:0019899 enzyme binding
1.74 3.34e-02 GO:XXXXXXX unannotated
1.56 1.87e-15 GO:0005515 protein binding
1.23 1.64e-07 GO:0005488 binding