Motif ID: GAGGUAG

Z-value: 1.288


Mature miRNA associated with seed GAGGUAG:

NamemiRBase Accession
mmu-let-7a MIMAT0000521
mmu-let-7b MIMAT0000522
mmu-let-7c MIMAT0000523
mmu-let-7d MIMAT0000383
mmu-let-7e MIMAT0000524
mmu-let-7f MIMAT0000525
mmu-let-7g MIMAT0000121
mmu-let-7i MIMAT0000122
mmu-miR-1961 MIMAT0009434
mmu-miR-98 MIMAT0000545



Activity profile for motif GAGGUAG.

activity profile for motif GAGGUAG


Sorted Z-values histogram for motif GAGGUAG

Sorted Z-values for motif GAGGUAG



Network of associatons between targets according to the STRING database.



First level regulatory network of GAGGUAG

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr16_-_22163264 10.476 NM_183029
Igf2bp2
insulin-like growth factor 2 mRNA binding protein 2
chr18_+_66618186 9.718 NM_021451
Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1
chr6_-_49164952 9.558 NM_023670
Igf2bp3
insulin-like growth factor 2 mRNA binding protein 3
chr17_+_33692639 9.364 NM_053214
Myo1f
myosin IF
chr3_+_30993952 8.902 NM_001039090
NM_011386
Skil

SKI-like

chr7_-_36370556 8.396 NM_145840
Rgs9bp
regulator of G-protein signalling 9 binding protein
chr6_-_47544925 8.283 NM_001146689
NM_007971
Ezh2

enhancer of zeste homolog 2 (Drosophila)

chr16_+_87699143 8.251 NM_007520
Bach1
BTB and CNC homology 1
chr5_+_30339682 8.070 NM_031168
Il6
interleukin 6
chr14_-_70999625 7.855 NM_194345
Fam160b2
family with sequence similarity 160, member B2
chr1_+_39957733 7.849 NM_008696
Map4k4
mitogen-activated protein kinase kinase kinase kinase 4
chr6_-_82724366 7.811 NM_013820
Hk2
hexokinase 2
chr10_-_18731766 7.708 NM_001166402
Tnfaip3
tumor necrosis factor, alpha-induced protein 3
chr2_+_167906462 7.683 NM_021409
Pard6b
par-6 (partitioning defective 6) homolog beta (C. elegans)
chr5_-_67819037 7.641 NM_001164806
Bend4
BEN domain containing 4
chr11_-_95867076 7.562 NM_009951
Igf2bp1
insulin-like growth factor 2 mRNA binding protein 1
chr6_-_38249209 7.300 NM_172467
Zc3hav1l
zinc finger CCCH-type, antiviral 1-like
chr16_-_19983049 7.299 NM_183390
Klhl6
kelch-like 6 (Drosophila)
chr13_-_64230610 7.244 NM_001001321
Slc35d2
solute carrier family 35, member D2
chr16_+_17233664 7.137 NM_178922
Hic2
hypermethylated in cancer 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 98 entries
Enrichment   P-value GO Accession GO Term
29.73 4.43e-03 GO:0035278 negative regulation of translation involved in gene silencing by miRNA
29.73 4.43e-03 GO:0040033 negative regulation of translation, ncRNA-mediated
29.73 4.43e-03 GO:0045974 regulation of translation, ncRNA-mediated
14.45 4.20e-04 GO:0035195 gene silencing by miRNA
13.69 6.50e-04 GO:0016441 posttranscriptional gene silencing
13.69 6.50e-04 GO:0035194 posttranscriptional gene silencing by RNA
10.14 2.60e-04 GO:0051897 positive regulation of protein kinase B signaling cascade
7.65 4.89e-02 GO:0031047 gene silencing by RNA
7.60 3.67e-03 GO:0051896 regulation of protein kinase B signaling cascade
5.11 1.64e-02 GO:0006403 RNA localization
5.08 1.09e-05 GO:0006417 regulation of translation
3.48 4.13e-04 GO:0010608 posttranscriptional regulation of gene expression
2.81 1.67e-03 GO:0009968 negative regulation of signal transduction
2.75 1.07e-03 GO:0010648 negative regulation of cell communication
2.72 1.63e-04 GO:0048585 negative regulation of response to stimulus
2.70 5.75e-03 GO:0010627 regulation of intracellular protein kinase cascade
2.67 3.11e-03 GO:0023057 negative regulation of signaling
2.47 4.24e-02 GO:0032583 regulation of gene-specific transcription
2.29 3.18e-02 GO:0008284 positive regulation of cell proliferation
2.28 1.17e-03 GO:0010558 negative regulation of macromolecule biosynthetic process

Gene overrepresentation in compartment category:

Showing 1 to 11 of 11 entries
Enrichment   P-value GO Accession GO Term
5.91 3.62e-02 GO:0005643 nuclear pore
1.58 1.52e-02 GO:0044428 nuclear part
1.51 3.32e-08 GO:0005634 nucleus
1.32 5.48e-07 GO:0043227 membrane-bounded organelle
1.32 7.31e-07 GO:0043231 intracellular membrane-bounded organelle
1.30 7.62e-08 GO:0043226 organelle
1.30 9.07e-08 GO:0043229 intracellular organelle
1.28 4.37e-10 GO:0005622 intracellular
1.28 2.01e-09 GO:0044424 intracellular part
1.13 8.49e-05 GO:0005623 cell
1.13 8.49e-05 GO:0044464 cell part

Gene overrepresentation in function category:

Showing 1 to 19 of 19 entries
Enrichment   P-value GO Accession GO Term
6.33 1.16e-02 GO:0004702 receptor signaling protein serine/threonine kinase activity
4.89 1.27e-02 GO:0005057 receptor signaling protein activity
3.30 3.61e-03 GO:0003682 chromatin binding
2.24 5.64e-03 GO:0004672 protein kinase activity
2.02 5.07e-03 GO:0016301 kinase activity
1.98 3.71e-02 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.95 2.23e-07 GO:0003677 DNA binding
1.95 4.66e-03 GO:0030528 transcription regulator activity
1.93 3.23e-02 GO:0001071 nucleic acid binding transcription factor activity
1.93 3.23e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.91 8.73e-05 GO:0008270 zinc ion binding
1.85 1.99e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.76 1.51e-07 GO:0003676 nucleic acid binding
1.76 4.50e-04 GO:0046914 transition metal ion binding
1.48 5.05e-04 GO:0046872 metal ion binding
1.47 9.37e-04 GO:0043169 cation binding
1.46 1.13e-03 GO:0043167 ion binding
1.36 1.65e-04 GO:0005515 protein binding
1.26 3.90e-08 GO:0005488 binding