Motif ID: GATA1..3.p2

Z-value: 4.339


Transcription factors associated with GATA1..3.p2:

Gene SymbolEntrez IDGene Name
Gata1 14460 GATA binding protein 1
Gata2 14461 GATA binding protein 2
Gata3 14462 GATA binding protein 3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gata1chrX_-_7544940-0.503.8e-13Click!
Gata3chr2_-_9800211-0.198.5e-03Click!
Gata2chr6_+_88148657-0.181.4e-02Click!


Activity profile for motif GATA1..3.p2.

activity profile for motif GATA1..3.p2


Sorted Z-values histogram for motif GATA1..3.p2

Sorted Z-values for motif GATA1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GATA1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chrX_+_54043764 106.852 Fhl1
four and a half LIM domains 1
chrX_+_10062237 95.283 NM_019634
Tspan7
tetraspanin 7
chr1_+_34364633 86.449 Dst
dystonin
chr17_-_90487479 68.183 Nrxn1
neurexin I
chr15_-_98780503 67.583 Tuba1a
tubulin, alpha 1A
chr14_-_55735114 66.513 NM_177049
Jph4
junctophilin 4
chr17_+_37210011 65.968 Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr1_+_34356614 65.347 Dst
dystonin
chr13_+_59234737 64.916 Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr12_+_110798661 64.591 Meg3
maternally expressed 3
chr15_+_91991704 63.371 NM_001159647
Cntn1
contactin 1
chr9_+_50561092 58.788 Cryab
crystallin, alpha B
chr9_+_50561315 57.849 Cryab
crystallin, alpha B
chr9_+_50561121 55.565 Cryab
crystallin, alpha B
chr15_-_98781060 55.431 Tuba1a
tubulin, alpha 1A
chr14_+_84933363 55.177 Pcdh17
protocadherin 17
chr12_-_112907828 54.631 Ckb
creatine kinase, brain
chr9_+_50560862 54.252 NM_009964
Cryab
crystallin, alpha B
chr4_+_43644806 54.043 NM_173788
Npr2
natriuretic peptide receptor 2
chrX_+_139952975 52.904 NM_001195048
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr9_+_75192367 52.614 Gnb5
guanine nucleotide binding protein (G protein), beta 5
chr11_+_68505416 49.711 NM_175260
Myh10
myosin, heavy polypeptide 10, non-muscle
chr17_+_71168939 49.270 Dlgap1
discs, large (Drosophila) homolog-associated protein 1
chr1_+_160292470 48.309 NM_007495
Astn1
astrotactin 1
chr7_+_138087002 48.178 Htra1
HtrA serine peptidase 1
chr11_+_87574041 47.458 NM_172449
Bzrap1
benzodiazepine receptor associated protein 1
chr3_+_68376289 47.092 NM_013928
Schip1
schwannomin interacting protein 1
chr12_-_102988596 46.185


chr18_-_43219062 44.474 NM_028392
Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr15_+_97923019 44.457 NM_001163488
Pfkm
phosphofructokinase, muscle
chr9_+_43877511 44.197 NM_016808
Usp2
ubiquitin specific peptidase 2
chr12_+_91570569 43.662 Nrxn3
neurexin III
chr9_+_120864938 43.554 Ctnnb1
catenin (cadherin associated protein), beta 1
chr8_-_67071497 43.449


chr1_+_160292665 43.407 Astn1
astrotactin 1
chr11_+_68505612 42.294 Myh10
myosin, heavy polypeptide 10, non-muscle
chr10_-_108447894 42.101 Syt1
synaptotagmin I
chr9_-_29770699 41.879 NM_172290
Ntm
neurotrimin
chr11_+_68505616 41.816 Myh10
myosin, heavy polypeptide 10, non-muscle
chr15_-_98638230 41.021 Ddn
dendrin
chr2_-_73497987 40.852 Chn1
chimerin (chimaerin) 1
chr9_-_49311823 40.348 Ncam1
neural cell adhesion molecule 1
chr9_+_50561381 40.145 Cryab
crystallin, alpha B
chr1_-_137063881 39.902 Gpr37l1
G protein-coupled receptor 37-like 1
chr2_+_61884596 39.653 NM_033552
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr17_+_37187984 39.384 Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr19_+_4745119 37.904 Spnb3
spectrin beta 3
chr19_+_10525829 37.127


chr1_+_154802198 36.995 NM_175460
Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr18_-_25912171 36.700 Celf4
CUGBP, Elav-like family member 4
chr9_-_73781373 36.380 NM_001081153
Unc13c
unc-13 homolog C (C. elegans)
chr1_+_66515003 36.351 NM_175510
Unc80
unc-80 homolog (C. elegans)
chr3_+_68376319 36.201 Schip1
schwannomin interacting protein 1
chr16_+_6349108 36.136 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr7_-_112717810 35.729 Apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1
chr3_-_83967952 35.514 Trim2
tripartite motif-containing 2
chr2_+_158436493 35.500 NM_009508
Slc32a1
solute carrier family 32 (GABA vesicular transporter), member 1
chr1_-_134264461 35.087 Tmcc2
transmembrane and coiled-coil domains 2
chr7_-_82453216 34.962 NM_001109753
Sv2b
synaptic vesicle glycoprotein 2 b
chr15_+_89284625 34.925 Mapk8ip2
mitogen-activated protein kinase 8 interacting protein 2
chr11_+_78139476 34.911 Aldoc
aldolase C, fructose-bisphosphate
chr15_-_98637560 34.897 Ddn
dendrin
chr19_+_4711207 34.503 Spnb3
spectrin beta 3
chrX_+_140127827 34.053 NM_001195046
NM_001195047
Pak3

p21 protein (Cdc42/Rac)-activated kinase 3

chr2_-_115890747 33.967 NM_001136072
NM_001159567
NM_001159568
NM_010825
Meis2



Meis homeobox 2



chr15_-_75920355 33.810 NM_144847
Nrbp2
nuclear receptor binding protein 2
chr10_-_108447674 33.376 NM_009306
Syt1
synaptotagmin I
chr3_-_81878554 32.807 NM_001161796
NM_017469
Gucy1b3

guanylate cyclase 1, soluble, beta 3

chr1_-_36758359 32.709 Actr1b
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr1_-_72905107 32.228 Igfbp5
insulin-like growth factor binding protein 5
chr2_-_25325248 32.016 NM_008963
Ptgds
prostaglandin D2 synthase (brain)
chr4_-_126427788 31.965 Ncdn
neurochondrin
chr16_-_45724422 31.888 NM_019754
Tagln3
transgelin 3
chr1_-_170361525 31.786 Pbx1
pre B-cell leukemia transcription factor 1
chr11_-_55233581 31.543 NM_009242
Sparc
secreted acidic cysteine rich glycoprotein
chr14_+_19103655 31.014 NM_023526
Nkiras1
NFKB inhibitor interacting Ras-like protein 1
chr2_-_25325196 30.731 Ptgds
prostaglandin D2 synthase (brain)
chr14_-_46149660 30.699 NM_146054
Fermt2
fermitin family homolog 2 (Drosophila)
chr10_-_108448003 30.672 Syt1
synaptotagmin I
chr17_-_25073897 30.549 NM_001163447
NM_001163448
NM_001163449
NM_001163450
NM_001163451
NM_001163453
NM_013931
Mapk8ip3






mitogen-activated protein kinase 8 interacting protein 3






chr4_-_61179982 30.518 Mup1
major urinary protein 1
chr2_+_49474775 30.274 NM_008449
Kif5c
kinesin family member 5C
chr2_+_28048511 30.223 Olfm1
olfactomedin 1
chr6_-_126658429 30.049


chr9_-_60535699 29.468 Lrrc49
leucine rich repeat containing 49
chr5_-_74464390 29.373 NM_177561
Usp46
ubiquitin specific peptidase 46
chr1_-_174221511 29.313 Atp1a2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr3_+_17954324 29.001 NM_021560
Bhlhe22
basic helix-loop-helix family, member e22
chr4_-_126430511 28.873 NM_011986
Ncdn
neurochondrin
chr17_-_25073798 28.851 Mapk8ip3
mitogen-activated protein kinase 8 interacting protein 3
chr11_+_87394609 28.811 NM_011129
Sept4
septin 4
chr9_+_27598853 28.614 NM_177906
Opcml
opioid binding protein/cell adhesion molecule-like
chr14_+_14286471 28.342 NM_001163032
Synpr
synaptoporin
chr15_+_34167908 28.254 Laptm4b
lysosomal-associated protein transmembrane 4B
chr2_+_28048779 27.984 Olfm1
olfactomedin 1
chr2_+_49474840 27.958 Kif5c
kinesin family member 5C
chr3_-_103541882 27.779 NM_133859
Olfml3
olfactomedin-like 3
chr11_+_94797565 27.674 NM_007742
Col1a1
collagen, type I, alpha 1
chr6_-_124414668 27.663 NM_153508
Clstn3
calsyntenin 3
chr19_+_25484006 27.444 Kank1
KN motif and ankyrin repeat domains 1
chr11_+_87394647 27.442 Sept4
septin 4
chr8_+_11443165 27.301 Col4a2
collagen, type IV, alpha 2
chr11_+_54128404 27.243 NM_001033599
Acsl6
acyl-CoA synthetase long-chain family member 6
chr8_-_85982247 27.189 NM_001039137
Scoc
short coiled-coil protein
chr2_+_136539143 26.963 NM_011428
Snap25
synaptosomal-associated protein 25
chr7_-_82453166 26.944 Sv2b
synaptic vesicle glycoprotein 2 b
chr15_+_89284341 26.712 NM_021921
Mapk8ip2
mitogen-activated protein kinase 8 interacting protein 2
chr15_+_34167780 26.683 NM_033521
Laptm4b
lysosomal-associated protein transmembrane 4B
chrX_+_162782484 26.555 NM_001177955
NM_001177956
NM_001177957
NM_001177958
NM_001177959
NM_001177960
Gpm6b





glycoprotein m6b





chr4_+_126872429 26.402 Dlgap3
discs, large (Drosophila) homolog-associated protein 3
chr10_+_90039435 26.341 NM_001177396
NM_001177398
NM_181398
Ipw
Anks1b


imprinted gene in the Prader-Willi syndrome region
ankyrin repeat and sterile alpha motif domain containing 1B


chrX_+_155897056 26.216 Mtap7d2
MAP7 domain containing 2
chr14_+_68701838 26.190 NM_010910
Nefl
neurofilament, light polypeptide
chr8_-_87296172 26.177 Nfix
nuclear factor I/X
chr2_-_52414072 26.161 NM_146123
Cacnb4
calcium channel, voltage-dependent, beta 4 subunit
chr2_+_136539202 26.132 Snap25
synaptosomal-associated protein 25
chr4_-_108311676 26.045


chr10_-_57252251 26.043 Serinc1
serine incorporator 1
chr2_-_79969095 26.002 NM_016744
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr1_-_45559866 25.979 Col5a2
collagen, type V, alpha 2
chr2_+_72018059 25.781 Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr1_+_9591492 25.735 3110035E14Rik
RIKEN cDNA 3110035E14 gene
chr8_-_48437701 25.734 NM_175162
Stox2
storkhead box 2
chr10_-_57252184 25.701 Serinc1
serine incorporator 1
chr19_-_42160732 25.663 NM_198108
Morn4
MORN repeat containing 4
chr9_-_95307645 25.488 NM_018763
Chst2
carbohydrate sulfotransferase 2
chr11_-_58768012 25.209 NM_206882
Hist3h2bb-ps
histone cluster 3, H2bb, pseudogene
chr13_+_23838602 25.192 NM_175664
Hist1h2bb
histone cluster 1, H2bb
chr1_-_36756687 25.055 Actr1b
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr1_-_164408008 24.848 Dnm3
dynamin 3
chr11_+_87394543 24.800 Sept4
septin 4
chr9_+_108382180 24.728 NM_008483
Lamb2
laminin, beta 2
chr1_-_45559904 24.647 Col5a2
collagen, type V, alpha 2
chr4_-_41717062 24.501 NM_011336
Ccl27a
chemokine (C-C motif) ligand 27A
chr4_-_41586992 24.501 Enho
energy homeostasis associated
chr2_+_177876635 24.254 NM_028806
Phactr3
phosphatase and actin regulator 3
chr1_+_87804443 24.244 Itm2c
integral membrane protein 2C
chr10_+_80643263 24.034 Eef2
eukaryotic translation elongation factor 2
chr9_-_83699706 23.886 NM_001145974
NM_148941
Elovl4

elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4

chr10_-_57252252 23.800 NM_019760
Serinc1
serine incorporator 1
chr14_+_56130147 23.664 NM_009947
Cpne6
copine VI
chr18_-_25912453 23.609 NM_001146292
NM_001146293
NM_001146294
NM_001146295
NM_001174074
NM_133195
Celf4





CUGBP, Elav-like family member 4





chr11_+_102466556 23.531 Fzd2
frizzled homolog 2 (Drosophila)
chrX_-_22797942 23.522 Klhl13
kelch-like 13 (Drosophila)
chr15_+_89284554 23.497 Mapk8ip2
mitogen-activated protein kinase 8 interacting protein 2
chr9_-_60535274 23.492 NM_001146047
Lrrc49
leucine rich repeat containing 49
chr14_-_76956445 23.463 NM_001160326
Serp2
stress-associated endoplasmic reticulum protein family member 2
chr10_-_108447996 23.447 Syt1
synaptotagmin I
chr11_-_55208276 23.391


chrX_+_45872593 23.305 NM_011228
Rab33a
RAB33A, member of RAS oncogene family
chr9_-_21822333 23.172 Elavl3
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
chr7_+_19661811 23.035 Dmwd
dystrophia myotonica-containing WD repeat motif
chr12_-_5091185 22.836 Klhl29
kelch-like 29 (Drosophila)
chr1_-_164408133 22.787 NM_001038619
NM_172646
Dnm3

dynamin 3

chr2_-_92232506 22.694 Mapk8ip1
mitogen-activated protein kinase 8 interacting protein 1
chr16_-_18622083 22.514


chr12_-_102988510 22.346 Fbln5
fibulin 5
chr1_+_12682572 22.296 Sulf1
sulfatase 1
chr16_+_41532938 22.227 Lsamp
limbic system-associated membrane protein
chr13_+_49704471 22.218 Ogn
osteoglycin
chr7_+_133966816 22.059 NM_029978
Fam57b
family with sequence similarity 57, member B
chr8_+_56122680 22.036 Gpm6a
glycoprotein m6a
chr7_+_134094045 22.026 NM_144926
Sez6l2
seizure related 6 homolog like 2
chr5_+_18732863 21.788 NM_001170746
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr1_+_45402907 21.689 Col3a1
collagen, type III, alpha 1
chr3_+_113733590 21.639 Col11a1
collagen, type XI, alpha 1
chr2_-_80421054 21.622 NM_016965
Nckap1
NCK-associated protein 1
chr3_-_103541868 21.568 Olfml3
olfactomedin-like 3
chr7_-_108025317 21.357 Arhgef17
Rho guanine nucleotide exchange factor (GEF) 17
chr2_+_65508501 21.321 NM_001099298
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chrX_+_38754480 21.321 NM_016886
Gria3
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr8_+_46593141 21.301 NM_172752
Sorbs2
sorbin and SH3 domain containing 2
chr11_+_97702591 21.270 B230217C12Rik
RIKEN cDNA B230217C12 gene
chr12_+_81619976 21.233 NM_001081421
Galntl1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase-like 1
chr14_-_94289847 21.187 Pcdh9
protocadherin 9
chr13_+_42961598 21.172 Phactr1
phosphatase and actin regulator 1
chr1_+_184695026 21.165 NM_144796
Susd4
sushi domain containing 4
chr9_+_108197453 21.138


chr1_+_45368443 21.087 Col3a1
collagen, type III, alpha 1
chr6_+_4471231 21.079 Col1a2
collagen, type I, alpha 2
chr6_+_88674821 21.069 Mgll
monoglyceride lipase
chr18_+_82723907 20.986 Mbp
myelin basic protein
chr3_+_115710360 20.974 NM_001163515
NM_021388
Extl2

exostoses (multiple)-like 2

chr18_+_82723854 20.960 NM_001025251
NM_001025255
NM_001025256
NM_001025258
NM_001025259
NM_001025254
Mbp





myelin basic protein





chrX_+_133357268 20.766 NM_011123
Plp1
proteolipid protein (myelin) 1
chr1_-_134287712 20.714 NM_178874
Tmcc2
transmembrane and coiled-coil domains 2
chr18_+_37921454 20.561 NM_033580
Pcdhgb8
protocadherin gamma subfamily B, 8
chr5_+_104888468 20.513 NM_008861
Pkd2
polycystic kidney disease 2
chr4_+_129985957 20.486 NM_010174
Fabp3
fatty acid binding protein 3, muscle and heart
chr6_-_58857000 20.478 NM_021432
Nap1l5
nucleosome assembly protein 1-like 5
chr9_+_68501551 20.430 NM_013646
Rora
RAR-related orphan receptor alpha
chr11_-_20729367 20.369 1110067D22Rik
RIKEN cDNA 1110067D22 gene
chr11_+_58762401 20.296 NM_030082
Hist3h2ba
histone cluster 3, H2ba
chr17_-_85489544 20.235 NM_001163622
NM_001163623
NM_145984
NM_001163624
Prepl



prolyl endopeptidase-like



chr9_+_21742717 20.198 NM_144935
BC018242
cDNA sequence BC018242
chr10_-_36855668 20.181 Marcks
myristoylated alanine rich protein kinase C substrate
chr14_-_109313298 20.125 Slitrk1
SLIT and NTRK-like family, member 1
chr4_+_126291095 20.073 5730409E04Rik
RIKEN cDNA 5730409E04Rik gene
chr7_-_74879894 20.027 Synm
synemin, intermediate filament protein
chr7_-_133938863 19.942



Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.45 7.38e-24 GO:0051179 localization
1.48 4.85e-22 GO:0006810 transport
1.48 6.87e-22 GO:0051234 establishment of localization
1.72 4.56e-19 GO:0007399 nervous system development
1.46 3.09e-15 GO:0071842 cellular component organization at cellular level
1.39 4.36e-15 GO:0016043 cellular component organization
1.44 6.30e-15 GO:0071841 cellular component organization or biogenesis at cellular level
1.37 1.92e-14 GO:0071840 cellular component organization or biogenesis
1.84 2.63e-13 GO:0007154 cell communication
2.17 1.52e-12 GO:0019226 transmission of nerve impulse
2.17 1.52e-12 GO:0035637 multicellular organismal signaling
1.37 1.92e-12 GO:0048856 anatomical structure development
1.38 1.09e-11 GO:0048731 system development
1.32 2.10e-11 GO:0032502 developmental process
1.69 2.82e-11 GO:0022008 neurogenesis
1.99 4.41e-11 GO:0007267 cell-cell signaling
2.00 5.51e-11 GO:0044057 regulation of system process
1.32 9.28e-11 GO:0007275 multicellular organismal development
1.11 1.79e-10 GO:0009987 cellular process
2.21 3.57e-10 GO:0007268 synaptic transmission
1.19 9.20e-10 GO:0044237 cellular metabolic process
1.67 1.07e-09 GO:0048699 generation of neurons
1.63 1.33e-09 GO:0048468 cell development
1.46 3.53e-09 GO:0023051 regulation of signaling
1.55 7.16e-09 GO:0051641 cellular localization
1.40 7.67e-09 GO:0065008 regulation of biological quality
1.60 9.53e-09 GO:0022607 cellular component assembly
1.60 2.06e-08 GO:0051128 regulation of cellular component organization
1.43 6.74e-08 GO:0006996 organelle organization
1.32 9.46e-08 GO:0048519 negative regulation of biological process
1.83 1.08e-07 GO:0048666 neuron development
1.52 1.27e-07 GO:0044085 cellular component biogenesis
1.69 1.51e-07 GO:0006812 cation transport
1.93 2.35e-07 GO:0031175 neuron projection development
1.51 2.53e-07 GO:0008104 protein localization
2.13 2.67e-07 GO:0031644 regulation of neurological system process
1.75 2.76e-07 GO:0030030 cell projection organization
1.33 3.18e-07 GO:0048523 negative regulation of cellular process
1.57 3.31e-07 GO:0006811 ion transport
1.16 5.52e-07 GO:0044238 primary metabolic process
1.49 6.32e-07 GO:0035556 intracellular signal transduction
2.15 6.45e-07 GO:0051969 regulation of transmission of nerve impulse
1.84 6.55e-07 GO:0007610 behavior
1.77 6.91e-07 GO:0007010 cytoskeleton organization
1.72 9.06e-07 GO:0030001 metal ion transport
1.86 9.23e-07 GO:0006163 purine nucleotide metabolic process
1.80 1.05e-06 GO:0060284 regulation of cell development
2.19 1.11e-06 GO:0050804 regulation of synaptic transmission
1.14 1.13e-06 GO:0008152 metabolic process
1.98 1.28e-06 GO:0045664 regulation of neuron differentiation
2.64 1.34e-06 GO:0006936 muscle contraction
1.66 1.36e-06 GO:0071844 cellular component assembly at cellular level
1.53 1.67e-06 GO:0051649 establishment of localization in cell
1.91 1.78e-06 GO:0015672 monovalent inorganic cation transport
1.39 2.33e-06 GO:0065009 regulation of molecular function
1.46 2.55e-06 GO:0010646 regulation of cell communication
2.04 3.35e-06 GO:0030029 actin filament-based process
1.61 4.46e-06 GO:0007155 cell adhesion
2.12 4.62e-06 GO:0031344 regulation of cell projection organization
1.38 5.20e-06 GO:0051239 regulation of multicellular organismal process
1.66 5.44e-06 GO:0030182 neuron differentiation
1.80 5.75e-06 GO:0051960 regulation of nervous system development
1.46 7.07e-06 GO:0032879 regulation of localization
2.05 7.69e-06 GO:0030036 actin cytoskeleton organization
1.60 8.19e-06 GO:0022610 biological adhesion
1.55 8.39e-06 GO:0051049 regulation of transport
1.76 8.78e-06 GO:0072521 purine-containing compound metabolic process
1.41 1.04e-05 GO:0009056 catabolic process
1.99 1.28e-05 GO:0007017 microtubule-based process
1.83 1.35e-05 GO:0050767 regulation of neurogenesis
2.03 1.61e-05 GO:0007409 axonogenesis
2.40 1.83e-05 GO:0003012 muscle system process
1.41 2.03e-05 GO:0033036 macromolecule localization
1.52 2.14e-05 GO:0015031 protein transport
1.60 2.26e-05 GO:0065003 macromolecular complex assembly
1.30 2.34e-05 GO:0048869 cellular developmental process
1.20 2.68e-05 GO:0019222 regulation of metabolic process
1.67 2.90e-05 GO:0032989 cellular component morphogenesis
1.59 2.97e-05 GO:0016192 vesicle-mediated transport
1.41 3.10e-05 GO:0050790 regulation of catalytic activity
2.47 3.44e-05 GO:0003001 generation of a signal involved in cell-cell signaling
2.47 3.44e-05 GO:0023061 signal release
1.30 3.86e-05 GO:0030154 cell differentiation
1.50 4.07e-05 GO:0045184 establishment of protein localization
1.83 4.11e-05 GO:0048858 cell projection morphogenesis
1.68 4.45e-05 GO:0055082 cellular chemical homeostasis
1.37 5.07e-05 GO:0009653 anatomical structure morphogenesis
2.48 6.33e-05 GO:0030534 adult behavior
2.12 6.34e-05 GO:0010975 regulation of neuron projection development
2.12 6.34e-05 GO:0042391 regulation of membrane potential
1.28 6.47e-05 GO:0044267 cellular protein metabolic process
1.68 7.72e-05 GO:0006873 cellular ion homeostasis
1.25 8.21e-05 GO:0019538 protein metabolic process
1.55 8.59e-05 GO:0043933 macromolecular complex subunit organization
2.73 8.96e-05 GO:0048167 regulation of synaptic plasticity
1.39 8.96e-05 GO:0009966 regulation of signal transduction
1.90 9.35e-05 GO:0048812 neuron projection morphogenesis
1.79 1.10e-04 GO:0032990 cell part morphogenesis
1.44 1.15e-04 GO:0032268 regulation of cellular protein metabolic process
1.90 1.62e-04 GO:0048667 cell morphogenesis involved in neuron differentiation
1.64 1.67e-04 GO:0034613 cellular protein localization
1.42 1.67e-04 GO:0044248 cellular catabolic process
1.24 2.02e-04 GO:0048518 positive regulation of biological process
1.63 2.45e-04 GO:0070727 cellular macromolecule localization
1.40 2.82e-04 GO:0051246 regulation of protein metabolic process
1.64 3.34e-04 GO:0000902 cell morphogenesis
2.55 3.90e-04 GO:0007018 microtubule-based movement
1.85 4.13e-04 GO:0032269 negative regulation of cellular protein metabolic process
1.81 4.22e-04 GO:0009144 purine nucleoside triphosphate metabolic process
1.61 4.41e-04 GO:0050801 ion homeostasis
1.76 4.87e-04 GO:0000904 cell morphogenesis involved in differentiation
1.77 6.26e-04 GO:0009150 purine ribonucleotide metabolic process
1.75 6.59e-04 GO:0034220 ion transmembrane transport
1.80 6.64e-04 GO:0007264 small GTPase mediated signal transduction
1.88 7.38e-04 GO:0051129 negative regulation of cellular component organization
1.80 7.58e-04 GO:0009205 purine ribonucleoside triphosphate metabolic process
1.96 8.11e-04 GO:0043269 regulation of ion transport
1.52 8.59e-04 GO:0046907 intracellular transport
1.59 9.01e-04 GO:0006753 nucleoside phosphate metabolic process
1.59 9.01e-04 GO:0009117 nucleotide metabolic process
1.46 1.02e-03 GO:0031399 regulation of protein modification process
1.55 1.02e-03 GO:0019725 cellular homeostasis
1.79 1.04e-03 GO:0009199 ribonucleoside triphosphate metabolic process
1.19 1.07e-03 GO:0031323 regulation of cellular metabolic process
1.74 1.17e-03 GO:0009259 ribonucleotide metabolic process
1.61 1.18e-03 GO:0006461 protein complex assembly
1.55 1.20e-03 GO:0055086 nucleobase, nucleoside and nucleotide metabolic process
1.23 1.26e-03 GO:0048522 positive regulation of cellular process
2.40 1.36e-03 GO:0034765 regulation of ion transmembrane transport
1.82 1.41e-03 GO:0051056 regulation of small GTPase mediated signal transduction
1.59 1.42e-03 GO:0071822 protein complex subunit organization
1.76 1.48e-03 GO:0009141 nucleoside triphosphate metabolic process
1.60 1.51e-03 GO:0070271 protein complex biogenesis
2.11 1.51e-03 GO:0007626 locomotory behavior
2.07 1.57e-03 GO:0006813 potassium ion transport
1.99 1.94e-03 GO:0006605 protein targeting
1.77 2.49e-03 GO:0051248 negative regulation of protein metabolic process
1.96 2.58e-03 GO:0043062 extracellular structure organization
1.76 2.96e-03 GO:0006511 ubiquitin-dependent protein catabolic process
1.79 3.63e-03 GO:0006195 purine nucleotide catabolic process
1.45 3.77e-03 GO:0055085 transmembrane transport
1.77 4.35e-03 GO:0072523 purine-containing compound catabolic process
2.04 4.53e-03 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.04 4.53e-03 GO:0022604 regulation of cell morphogenesis
1.64 4.55e-03 GO:0009628 response to abiotic stimulus
1.42 5.23e-03 GO:0045595 regulation of cell differentiation
2.53 6.39e-03 GO:0008344 adult locomotory behavior
2.98 6.96e-03 GO:0007269 neurotransmitter secretion
1.73 7.14e-03 GO:0009166 nucleotide catabolic process
1.72 7.20e-03 GO:0019941 modification-dependent protein catabolic process
1.79 7.24e-03 GO:0009261 ribonucleotide catabolic process
1.74 8.00e-03 GO:0061061 muscle structure development
1.57 8.01e-03 GO:0023057 negative regulation of signaling
1.81 8.03e-03 GO:0009207 purine ribonucleoside triphosphate catabolic process
1.79 8.26e-03 GO:0009154 purine ribonucleotide catabolic process
2.07 8.39e-03 GO:0072522 purine-containing compound biosynthetic process
1.47 8.86e-03 GO:0046483 heterocycle metabolic process
1.57 8.98e-03 GO:0010648 negative regulation of cell communication
1.39 9.07e-03 GO:2000026 regulation of multicellular organismal development
1.64 9.29e-03 GO:0006886 intracellular protein transport
1.80 9.43e-03 GO:0009203 ribonucleoside triphosphate catabolic process
1.71 9.58e-03 GO:0043632 modification-dependent macromolecule catabolic process
1.69 9.64e-03 GO:0034655 nucleobase, nucleoside, nucleotide and nucleic acid catabolic process
1.69 9.64e-03 GO:0034656 nucleobase, nucleoside and nucleotide catabolic process
2.10 1.01e-02 GO:0006164 purine nucleotide biosynthetic process
4.14 1.02e-02 GO:0001578 microtubule bundle formation
2.56 1.17e-02 GO:0050680 negative regulation of epithelial cell proliferation
2.51 1.20e-02 GO:0007156 homophilic cell adhesion
1.66 1.25e-02 GO:0034621 cellular macromolecular complex subunit organization
1.70 1.27e-02 GO:0034622 cellular macromolecular complex assembly
1.78 1.30e-02 GO:0009146 purine nucleoside triphosphate catabolic process
1.27 1.47e-02 GO:0048583 regulation of response to stimulus
1.84 1.49e-02 GO:0033365 protein localization to organelle
2.65 1.50e-02 GO:0006754 ATP biosynthetic process
1.64 1.60e-02 GO:0046903 secretion
1.17 1.70e-02 GO:0080090 regulation of primary metabolic process
1.09 1.80e-02 GO:0065007 biological regulation
1.90 1.88e-02 GO:0031400 negative regulation of protein modification process
1.45 1.89e-02 GO:0048878 chemical homeostasis
1.34 1.98e-02 GO:0050793 regulation of developmental process
2.54 2.21e-02 GO:0070588 calcium ion transmembrane transport
2.23 2.44e-02 GO:0006836 neurotransmitter transport
1.66 2.49e-02 GO:0044257 cellular protein catabolic process
1.66 2.50e-02 GO:0051603 proteolysis involved in cellular protein catabolic process
1.74 2.79e-02 GO:0009143 nucleoside triphosphate catabolic process
1.74 2.79e-02 GO:0032940 secretion by cell
1.62 3.09e-02 GO:0030163 protein catabolic process
3.01 3.44e-02 GO:0035303 regulation of dephosphorylation
2.73 3.57e-02 GO:0003231 cardiac ventricle development
1.76 3.60e-02 GO:0046578 regulation of Ras protein signal transduction
1.42 3.85e-02 GO:0019220 regulation of phosphate metabolic process
1.42 3.85e-02 GO:0051174 regulation of phosphorus metabolic process
2.33 3.92e-02 GO:0001505 regulation of neurotransmitter levels
2.41 4.15e-02 GO:0009145 purine nucleoside triphosphate biosynthetic process
1.47 4.16e-02 GO:0072358 cardiovascular system development
1.47 4.16e-02 GO:0072359 circulatory system development
2.21 4.33e-02 GO:0006414 translational elongation
2.07 4.52e-02 GO:0051640 organelle localization
1.49 4.53e-02 GO:0044282 small molecule catabolic process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.34 1.26e-52 GO:0005737 cytoplasm
1.24 5.12e-48 GO:0005622 intracellular
1.24 6.41e-46 GO:0044424 intracellular part
2.42 2.32e-34 GO:0043005 neuron projection
1.36 1.53e-32 GO:0044444 cytoplasmic part
1.90 1.76e-28 GO:0042995 cell projection
1.11 1.28e-27 GO:0005623 cell
1.11 1.28e-27 GO:0044464 cell part
1.22 2.02e-27 GO:0043226 organelle
1.22 2.14e-27 GO:0043229 intracellular organelle
2.32 1.62e-25 GO:0045202 synapse
1.42 1.04e-22 GO:0032991 macromolecular complex
2.58 1.61e-20 GO:0030425 dendrite
2.46 2.67e-20 GO:0043025 neuronal cell body
1.44 3.55e-20 GO:0043234 protein complex
2.27 4.42e-20 GO:0044463 cell projection part
2.41 8.79e-20 GO:0044297 cell body
1.69 7.03e-19 GO:0000267 cell fraction
2.57 1.71e-18 GO:0030424 axon
2.32 2.45e-17 GO:0044456 synapse part
1.74 3.84e-16 GO:0005626 insoluble fraction
1.74 1.61e-15 GO:0005624 membrane fraction
1.54 2.17e-14 GO:0005856 cytoskeleton
1.17 3.04e-14 GO:0043227 membrane-bounded organelle
1.17 3.59e-14 GO:0043231 intracellular membrane-bounded organelle
1.30 1.34e-13 GO:0071944 cell periphery
1.29 1.34e-12 GO:0005886 plasma membrane
1.49 6.72e-12 GO:0005829 cytosol
2.83 7.22e-12 GO:0033267 axon part
1.37 9.28e-12 GO:0043228 non-membrane-bounded organelle
1.37 9.28e-12 GO:0043232 intracellular non-membrane-bounded organelle
2.75 3.47e-11 GO:0019717 synaptosome
1.25 2.22e-10 GO:0044446 intracellular organelle part
1.24 3.86e-10 GO:0044422 organelle part
1.70 1.88e-09 GO:0030054 cell junction
1.39 2.04e-09 GO:0044459 plasma membrane part
1.56 3.00e-09 GO:0044430 cytoskeletal part
2.97 3.37e-08 GO:0030427 site of polarized growth
2.92 1.98e-07 GO:0030426 growth cone
2.77 1.94e-06 GO:0014069 postsynaptic density
2.20 3.19e-06 GO:0045211 postsynaptic membrane
2.80 6.39e-06 GO:0044309 neuron spine
2.11 8.93e-06 GO:0031252 cell leading edge
2.79 1.23e-05 GO:0043197 dendritic spine
2.46 1.33e-05 GO:0034703 cation channel complex
1.80 1.87e-05 GO:0048471 perinuclear region of cytoplasm
1.38 2.27e-05 GO:0031090 organelle membrane
3.81 3.02e-05 GO:0044304 main axon
1.76 3.91e-04 GO:0005874 microtubule
2.35 5.12e-04 GO:0030017 sarcomere
1.64 5.42e-04 GO:0005625 soluble fraction
2.99 5.43e-04 GO:0016528 sarcoplasm
1.73 5.50e-04 GO:0015629 actin cytoskeleton
1.49 7.90e-04 GO:0015630 microtubule cytoskeleton
1.37 8.06e-04 GO:0005794 Golgi apparatus
1.91 1.16e-03 GO:0034702 ion channel complex
2.45 1.36e-03 GO:0005875 microtubule associated complex
1.64 1.43e-03 GO:0031012 extracellular matrix
3.11 1.68e-03 GO:0043198 dendritic shaft
1.50 1.72e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
2.13 1.86e-03 GO:0030016 myofibril
1.49 1.94e-03 GO:0031988 membrane-bounded vesicle
2.97 2.11e-03 GO:0016529 sarcoplasmic reticulum
2.06 2.43e-03 GO:0043292 contractile fiber
1.39 2.71e-03 GO:0012505 endomembrane system
1.41 2.98e-03 GO:0031410 cytoplasmic vesicle
2.12 4.86e-03 GO:0044449 contractile fiber part
2.26 5.48e-03 GO:0044306 neuron projection terminus
1.64 6.50e-03 GO:0005578 proteinaceous extracellular matrix
1.26 7.13e-03 GO:0005739 mitochondrion
6.56 7.23e-03 GO:0031512 motile primary cilium
2.12 9.22e-03 GO:0008021 synaptic vesicle
2.02 9.64e-03 GO:0044420 extracellular matrix part
1.37 1.06e-02 GO:0031982 vesicle
1.33 1.13e-02 GO:0044421 extracellular region part
1.82 1.50e-02 GO:0030135 coated vesicle
1.84 1.65e-02 GO:0030659 cytoplasmic vesicle membrane
1.82 1.71e-02 GO:0044433 cytoplasmic vesicle part
1.49 1.79e-02 GO:0005740 mitochondrial envelope
4.77 1.79e-02 GO:0060076 excitatory synapse
1.08 1.80e-02 GO:0016020 membrane
1.98 1.99e-02 GO:0044445 cytosolic part
2.16 2.08e-02 GO:0030027 lamellipodium
3.86 2.67e-02 GO:0005871 kinesin complex
1.84 2.89e-02 GO:0030136 clathrin-coated vesicle
2.19 3.10e-02 GO:0043679 axon terminus
1.29 3.42e-02 GO:0005783 endoplasmic reticulum
1.57 4.13e-02 GO:0044431 Golgi apparatus part
1.47 4.20e-02 GO:0031966 mitochondrial membrane
1.74 4.54e-02 GO:0012506 vesicle membrane
3.44 4.67e-02 GO:0034704 calcium channel complex
6.56 4.75e-02 GO:0033268 node of Ranvier

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.36 3.57e-35 GO:0005515 protein binding
1.20 1.62e-30 GO:0005488 binding
1.81 3.51e-10 GO:0008092 cytoskeletal protein binding
1.74 9.96e-08 GO:0008324 cation transmembrane transporter activity
1.54 1.71e-07 GO:0022857 transmembrane transporter activity
1.48 2.20e-07 GO:0005215 transporter activity
2.22 3.56e-07 GO:0005244 voltage-gated ion channel activity
2.22 3.56e-07 GO:0022832 voltage-gated channel activity
2.45 4.17e-07 GO:0022843 voltage-gated cation channel activity
1.59 5.61e-07 GO:0015075 ion transmembrane transporter activity
1.51 7.40e-07 GO:0022892 substrate-specific transporter activity
1.78 7.92e-07 GO:0005198 structural molecule activity
1.93 9.55e-07 GO:0022836 gated channel activity
1.30 1.66e-06 GO:0000166 nucleotide binding
1.53 2.71e-06 GO:0022891 substrate-specific transmembrane transporter activity
1.32 6.49e-06 GO:0032553 ribonucleotide binding
1.63 7.94e-06 GO:0005509 calcium ion binding
1.32 8.90e-06 GO:0032555 purine ribonucleotide binding
1.32 1.36e-05 GO:0035639 purine ribonucleoside triphosphate binding
1.31 1.41e-05 GO:0017076 purine nucleotide binding
1.70 2.65e-05 GO:0015267 channel activity
1.70 3.05e-05 GO:0022803 passive transmembrane transporter activity
1.60 3.46e-05 GO:0019904 protein domain specific binding
1.72 4.52e-05 GO:0032403 protein complex binding
1.52 5.23e-05 GO:0016818 hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
1.71 5.28e-05 GO:0005216 ion channel activity
1.52 5.81e-05 GO:0016817 hydrolase activity, acting on acid anhydrides
1.67 6.03e-05 GO:0060589 nucleoside-triphosphatase regulator activity
1.52 6.66e-05 GO:0016462 pyrophosphatase activity
1.86 8.00e-05 GO:0005261 cation channel activity
1.53 8.04e-05 GO:0017111 nucleoside-triphosphatase activity
1.67 1.59e-04 GO:0022838 substrate-specific channel activity
1.65 1.78e-04 GO:0030695 GTPase regulator activity
1.42 4.13e-04 GO:0030234 enzyme regulator activity
1.80 4.63e-04 GO:0005083 small GTPase regulator activity
1.67 4.78e-04 GO:0019001 guanyl nucleotide binding
1.67 4.78e-04 GO:0032561 guanyl ribonucleotide binding
2.17 5.50e-04 GO:0005267 potassium channel activity
1.40 1.03e-03 GO:0019899 enzyme binding
2.00 1.61e-03 GO:0003924 GTPase activity
1.65 1.62e-03 GO:0005525 GTP binding
5.37 1.77e-03 GO:0046933 hydrogen ion transporting ATP synthase activity, rotational mechanism
1.18 2.91e-03 GO:0046872 metal ion binding
3.28 4.17e-03 GO:0035254 glutamate receptor binding
3.94 5.74e-03 GO:0045309 protein phosphorylated amino acid binding
1.64 6.34e-03 GO:0003779 actin binding
1.17 7.77e-03 GO:0043167 ion binding
1.16 9.91e-03 GO:0043169 cation binding
1.92 1.09e-02 GO:0015077 monovalent inorganic cation transmembrane transporter activity
2.02 1.64e-02 GO:0003774 motor activity
4.22 4.16e-02 GO:0019894 kinesin binding