Motif ID: GFI1.p2

Z-value: 2.190


Transcription factors associated with GFI1.p2:

Gene SymbolEntrez IDGene Name
Gfi1 14581 growth factor independent 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gfi1chr5_-_1081533370.121.1e-01Click!


Activity profile for motif GFI1.p2.

activity profile for motif GFI1.p2


Sorted Z-values histogram for motif GFI1.p2

Sorted Z-values for motif GFI1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_86479405 71.292 NM_024184
 Asf1b
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr3_-_27052733 52.685 NM_001177625
NM_007900
 Ect2

ect2 oncogene

chr14_-_68333666 50.852 NM_001110162
 Cdca2
cell division cycle associated 2
chr3_-_27052794 45.522 NM_001177626
 Ect2
ect2 oncogene
chr11_-_98885428 41.405 NM_011623
 Top2a
topoisomerase (DNA) II alpha
chr14_-_68333897 41.092 NM_175384
 Cdca2
cell division cycle associated 2
chr2_+_164595415 36.748 NM_026785
 Ube2c
ubiquitin-conjugating enzyme E2C
chr16_-_18811669 36.287 NM_001161623
 Cdc45
cell division cycle 45 homolog (S. cerevisiae)
chr2_+_164595447 36.161 Ube2c
ubiquitin-conjugating enzyme E2C
chr2_-_172195998 35.553 NM_011497
 Aurka
aurora kinase A
chr2_+_164595389 35.147 Ube2c
ubiquitin-conjugating enzyme E2C
chr4_-_124614072 31.802 NM_026560
 Cdca8
cell division cycle associated 8
chr13_+_51740600 29.980 NM_025415
 Cks2
CDC28 protein kinase regulatory subunit 2
chr13_+_51740804 29.448 Cks2
CDC28 protein kinase regulatory subunit 2
chr11_+_86922732 26.792 NM_025377
 Fam33a
family with sequence similarity 33, member A
chr13_+_105019053 25.543 Cenpk
centromere protein K
chr17_-_34027575 25.005 NM_001195298
 Kifc1
kinesin family member C1
chr6_-_125141525 25.002 NM_146171
 Ncapd2
non-SMC condensin I complex, subunit D2
chr13_+_105019025 24.810 NM_181061
 Cenpk
centromere protein K
chr16_-_15637390 23.861 NM_008565
 Mcm4
minichromosome maintenance deficient 4 homolog (S. cerevisiae)

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 93 entries
Enrichment   P-value GO Accession GO Term
4.10 1.59e-02 GO:0030010 establishment of cell polarity
2.77 3.16e-06 GO:0006260 DNA replication
2.74 1.20e-09 GO:0000087 M phase of mitotic cell cycle
2.66 1.73e-08 GO:0000280 nuclear division
2.66 1.73e-08 GO:0007067 mitosis
2.63 3.60e-02 GO:0000075 cell cycle checkpoint
2.62 1.02e-02 GO:0006310 DNA recombination
2.55 9.67e-08 GO:0048285 organelle fission
2.51 1.71e-02 GO:0010639 negative regulation of organelle organization
2.50 3.95e-02 GO:0007059 chromosome segregation
2.44 1.72e-10 GO:0000279 M phase
2.41 7.74e-10 GO:0051301 cell division
2.28 1.13e-10 GO:0022403 cell cycle phase
2.26 4.30e-09 GO:0000278 mitotic cell cycle
2.25 1.49e-02 GO:0045786 negative regulation of cell cycle
2.24 3.53e-03 GO:0007346 regulation of mitotic cell cycle
2.17 1.36e-12 GO:0022402 cell cycle process
2.17 1.51e-03 GO:0010564 regulation of cell cycle process
2.12 1.32e-08 GO:0051726 regulation of cell cycle
2.12 2.73e-07 GO:0006974 response to DNA damage stimulus

Gene overrepresentation in compartment category:

Showing 1 to 20 of 36 entries
Enrichment   P-value GO Accession GO Term
3.33 4.35e-03 GO:0030496 midbody
3.18 1.48e-02 GO:0016363 nuclear matrix
3.14 3.04e-05 GO:0000776 kinetochore
2.39 1.49e-03 GO:0000775 chromosome, centromeric region
2.39 8.52e-03 GO:0005819 spindle
2.39 2.52e-02 GO:0000793 condensed chromosome
2.21 4.00e-10 GO:0044427 chromosomal part
2.18 1.29e-03 GO:0044454 nuclear chromosome part
2.16 4.04e-04 GO:0000228 nuclear chromosome
2.15 3.73e-10 GO:0005694 chromosome
1.98 8.48e-03 GO:0000785 chromatin
1.80 9.40e-12 GO:0005654 nucleoplasm
1.73 7.50e-15 GO:0031981 nuclear lumen
1.70 1.19e-02 GO:0005730 nucleolus
1.69 1.70e-05 GO:0044451 nucleoplasm part
1.66 2.44e-15 GO:0044428 nuclear part
1.60 9.16e-12 GO:0070013 intracellular organelle lumen
1.59 1.14e-11 GO:0043233 organelle lumen
1.57 6.38e-11 GO:0031974 membrane-enclosed lumen
1.48 4.42e-30 GO:0005634 nucleus

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
Enrichment   P-value GO Accession GO Term
3.47 1.47e-02 GO:0008094 DNA-dependent ATPase activity
2.20 3.72e-04 GO:0003682 chromatin binding
1.53 1.32e-09 GO:0003677 DNA binding
1.53 6.59e-03 GO:0003723 RNA binding
1.51 3.89e-14 GO:0003676 nucleic acid binding
1.48 3.04e-03 GO:0030528 transcription regulator activity
1.48 2.09e-02 GO:0001071 nucleic acid binding transcription factor activity
1.48 2.09e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
1.44 5.74e-05 GO:0005524 ATP binding
1.43 8.50e-05 GO:0032559 adenyl ribonucleotide binding
1.42 1.22e-04 GO:0030554 adenyl nucleotide binding
1.35 8.71e-04 GO:0032555 purine ribonucleotide binding
1.35 9.09e-04 GO:0032553 ribonucleotide binding
1.35 1.41e-03 GO:0035639 purine ribonucleoside triphosphate binding
1.34 1.43e-04 GO:0000166 nucleotide binding
1.34 1.17e-03 GO:0017076 purine nucleotide binding
1.22 1.16e-06 GO:0005515 protein binding
1.15 1.16e-10 GO:0005488 binding