Motif ID: GFI1B.p2

Z-value: 1.303


Transcription factors associated with GFI1B.p2:

Gene SymbolEntrez IDGene Name
Gfi1b 14582 growth factor independent 1B

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gfi1bchr2_-_28477437-0.492.2e-12Click!


Activity profile for motif GFI1B.p2.

activity profile for motif GFI1B.p2


Sorted Z-values histogram for motif GFI1B.p2

Sorted Z-values for motif GFI1B.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GFI1B.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr10_+_96945972 51.205 Dcn
decorin
chr5_-_104542751 40.270 Sparcl1
SPARC-like 1
chr5_-_104542729 38.630 Sparcl1
SPARC-like 1
chr5_-_104542641 38.283 Sparcl1
SPARC-like 1
chr5_-_104542598 32.939 Sparcl1
SPARC-like 1
chr1_-_45559904 26.642 Col5a2
collagen, type V, alpha 2
chr19_+_38598686 23.576 NM_019588
Plce1
phospholipase C, epsilon 1
chr16_+_45094196 23.153 Ccdc80
coiled-coil domain containing 80
chr16_+_45094163 23.030 NM_026439
Ccdc80
coiled-coil domain containing 80
chr16_+_45093784 22.852 Ccdc80
coiled-coil domain containing 80
chr1_-_45559866 22.694 Col5a2
collagen, type V, alpha 2
chr5_+_44053634 22.058 NM_172274
Cc2d2a
coiled-coil and C2 domain containing 2A
chr4_-_60235470 18.527 NM_001134676
Mup8
major urinary protein 8
chr13_+_23663264 17.730 NM_178196
Hist1h2bg
histone cluster 1, H2bg
chr12_+_77182878 17.383 Syne2
synaptic nuclear envelope 2
chr3_+_137940628 15.756 Adh1
alcohol dehydrogenase 1 (class I)
chr8_-_67071497 14.783


chr1_-_45559700 14.751 Col5a2
collagen, type V, alpha 2
chr1_-_45560001 14.280 NM_007737
Col5a2
collagen, type V, alpha 2
chr1_-_142079842 12.699 NM_009888
Cfh
complement component factor h
chr2_+_74536030 12.569 Hoxd9
homeobox D9
chr16_+_92498378 12.216 NM_172469
Clic6
chloride intracellular channel 6
chr18_+_44493726 11.828 NM_001033621
Myot
myotilin
chr18_-_35881144 11.536 NM_001033141
Ecscr
endothelial cell-specific chemotaxis regulator
chr5_-_44485951 11.398 NM_001163578
NM_001163581
NM_001163582
NM_001163583
NM_001163584
NM_001163585
Prom1





prominin 1





chrX_+_160811667 11.382 Figf
c-fos induced growth factor
chr10_+_12810593 10.915 NM_009538
Plagl1
pleiomorphic adenoma gene-like 1
chr8_-_64069935 10.485 Palld
palladin, cytoskeletal associated protein
chr19_+_23240506 10.267 Klf9
Kruppel-like factor 9
chr3_+_54165028 10.150 NM_001198765
NM_001198766
NM_015784
Postn


periostin, osteoblast specific factor


chr1_+_155756310 10.114 Glul
glutamate-ammonia ligase (glutamine synthetase)
chr2_+_143741050 9.998 NM_019771
Dstn
destrin
chr10_+_21712008 9.772 NM_001161849
Sgk1
serum/glucocorticoid regulated kinase 1
chr16_+_34995000 9.528 Mylk
myosin, light polypeptide kinase
chr18_+_23468585 9.346 Dtna
dystrobrevin alpha
chr16_+_45093816 9.259 Ccdc80
coiled-coil domain containing 80
chr3_-_113277601 9.199 NM_007446
Amy1
amylase 1, salivary
chr8_+_46593141 9.053 NM_172752
Sorbs2
sorbin and SH3 domain containing 2
chr16_-_84955488 8.909 App
amyloid beta (A4) precursor protein
chr15_-_3329691 8.523


chr4_-_147247909 8.074


chr2_-_34916915 8.033 NM_010406
Hc
hemolytic complement
chr10_+_94038001 7.789 NM_001168684
Tmcc3
transmembrane and coiled coil domains 3
chr18_+_44166024 7.773 Spink5
serine peptidase inhibitor, Kazal type 5
chr7_+_30969184 7.757 NM_009944
Cox7a1
cytochrome c oxidase, subunit VIIa 1
chr6_-_92431385 7.369 NM_001134460
Prickle2
prickle homolog 2 (Drosophila)
chr5_-_51945054 7.315 NM_008904
Ppargc1a
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr6_+_121956815 7.183 NM_008646
Mug2
murinoglobulin 2
chr6_+_121788537 7.107 NM_008645
Mug1
murinoglobulin 1
chr6_+_122463595 7.051 Mfap5
microfibrillar associated protein 5
chr6_+_121788594 6.687 Mug1
murinoglobulin 1
chr4_-_60889249 6.609 NM_001134674
Mup13
Mup19
Mup1
major urinary protein 13
major urinary protein 19
major urinary protein 1
chr5_-_17355533 6.407 NM_001159556
NM_001159557
Cd36

CD36 antigen

chr8_+_71404491 6.349 Lpl
lipoprotein lipase
chr13_+_42396844 6.319 Edn1
endothelin 1
chr14_+_120724380 6.274 Mbnl2
muscleblind-like 2
chr10_+_12810660 6.229 Plagl1
pleiomorphic adenoma gene-like 1
chr3_+_137949734 6.197 Adh1
alcohol dehydrogenase 1 (class I)
chr5_+_15440508 6.193 NM_001110843
NM_001110844
NM_001110845
NM_001110846
NM_009784
Cacna2d1




calcium channel, voltage-dependent, alpha2/delta subunit 1




chr8_-_81923366 6.072 NM_008539
Smad1
MAD homolog 1 (Drosophila)
chr11_+_112643501 6.067 NM_011448
Sox9
SRY-box containing gene 9
chr2_-_85359091 6.031 NM_001081664
4833423E24Rik
RIKEN cDNA 4833423E24 gene
chr18_+_23468655 6.009 Dtna
dystrobrevin alpha
chr10_+_18189773 5.963 NM_001163592
Nhsl1
NHS-like 1
chr1_+_74589461 5.864 NM_001081456
Plcd4
phospholipase C, delta 4
chr12_+_110783593 5.802 Meg3
maternally expressed 3
chr8_-_120197535 5.744 Sdr42e1
short chain dehydrogenase/reductase family 42E, member 1
chr16_+_45094214 5.631 Ccdc80
coiled-coil domain containing 80
chr4_-_60083171 5.627 Mup7
Mup1
major urinary protein 7
major urinary protein 1
chr11_+_75275123 5.578 2210403K04Rik
RIKEN cDNA 2210403K04 gene
chr4_-_60083321 5.360 NM_001134675
Mup7
major urinary protein 7
chr9_+_75192367 5.244 Gnb5
guanine nucleotide binding protein (G protein), beta 5
chr4_-_60675161 5.049 NM_001164526
NM_001134644
NM_001045550
NM_008647
Mup10
Mup11
LOC100048885
Mup19
Mup1
Mup2

major urinary protein 10
major urinary protein 11
major urinary protein LOC100048885
major urinary protein 19
major urinary protein 1
major urinary protein 2

chr15_-_103395483 5.027 NM_008134
Glycam1
glycosylation dependent cell adhesion molecule 1
chr18_+_23656024 5.018 Dtna
dystrobrevin alpha
chr10_-_61693914 4.850 Tspan15
tetraspanin 15
chr15_-_96861590 4.750 Slc38a4
solute carrier family 38, member 4
chr14_-_104243474 4.731 Ednrb
endothelin receptor type B
chr7_-_109082300 4.692 NM_001162973
NM_027053
Lrrc51

leucine rich repeat containing 51

chr16_+_34994935 4.609 Mylk
myosin, light polypeptide kinase
chr7_-_28122694 4.531 Ltbp4
latent transforming growth factor beta binding protein 4
chr10_-_75243786 4.442 Gstt3
glutathione S-transferase, theta 3
chr14_-_104243541 4.437 Ednrb
endothelin receptor type B
chr5_-_67009992 4.405 Apbb2
amyloid beta (A4) precursor protein-binding, family B, member 2
chr4_+_100449274 4.389 NM_198037
Cachd1
cache domain containing 1
chr16_-_85056592 4.321 App
amyloid beta (A4) precursor protein
chr11_+_62364951 4.278 NM_011664
Ubb
ubiquitin B
chr1_-_36756687 4.258 Actr1b
ARP1 actin-related protein 1 homolog B, centractin beta (yeast)
chr12_+_32123083 4.242 NM_021353
Slc26a3
solute carrier family 26, member 3
chr2_-_110145819 4.239 Bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr4_-_61443185 4.227 NM_001135127
Mup10
LOC100048884
Mup19
Mup1
major urinary protein 10
novel member of the major urinary protein (Mup) gene family
major urinary protein 19
major urinary protein 1
chr7_-_28122615 4.177 NM_175641
Ltbp4
latent transforming growth factor beta binding protein 4
chr1_-_170362298 4.158 Pbx1
pre B-cell leukemia transcription factor 1
chr10_-_70386552 4.151 Bicc1
bicaudal C homolog 1 (Drosophila)
chr18_+_61265225 4.118 NM_001037859
Csf1r
colony stimulating factor 1 receptor
chr4_-_60434715 4.030 NM_001126319
Mup9
Mup10
LOC100048884
Mup19
Mup1
Mup2
major urinary protein 9
major urinary protein 10
novel member of the major urinary protein (Mup) gene family
major urinary protein 19
major urinary protein 1
major urinary protein 2
chr7_-_106501584 3.913 Serpinh1
serine (or cysteine) peptidase inhibitor, clade H, member 1
chr4_-_61335031 3.887 Mup10
LOC100048884
Mup19
Mup1
Mup2
major urinary protein 10
novel member of the major urinary protein (Mup) gene family
major urinary protein 19
major urinary protein 1
major urinary protein 2
chr1_+_108757767 3.870 Serpinb5
serine (or cysteine) peptidase inhibitor, clade B, member 5
chr6_-_72312366 3.836 NM_025607
Rnf181
ring finger protein 181
chr12_+_110784600 3.800 Meg3
maternally expressed 3
chr10_-_116729893 3.767 NM_013590
Lyz1
lysozyme 1
chr8_-_87417792 3.734 NM_001044744
NM_008097
Gcdh

glutaryl-Coenzyme A dehydrogenase

chr19_+_29999624 3.716 Il33
interleukin 33
chr9_-_101154160 3.654 NM_001161362
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr11_-_65601657 3.631 Map2k4
mitogen-activated protein kinase kinase 4
chr3_-_107746550 3.624 NM_008184
Gstm6
glutathione S-transferase, mu 6
chr6_-_58974400 3.601 NM_153574
Fam13a
family with sequence similarity 13, member A
chr7_-_147268395 3.568 NM_001190385
NM_026769
Caly

calcyon neuron-specific vesicular protein

chr14_-_104243379 3.549 NM_001136061
Ednrb
endothelin receptor type B
chr3_+_59885811 3.548 Sucnr1
succinate receptor 1
chr19_+_29999596 3.545 NM_133775
Il33
interleukin 33
chr9_-_117161564 3.543 NM_001172122
NM_001172123
NM_001172124
NM_001172126
NM_178660
Rbms3




RNA binding motif, single stranded interacting protein




chr4_-_60594959 3.446 NM_001122647
Mup10
LOC100048884
Mup1
major urinary protein 10
novel member of the major urinary protein (Mup) gene family
major urinary protein 1
chr9_+_72596925 3.405 Nedd4
neural precursor cell expressed, developmentally down-regulated 4
chr17_-_35309483 3.381 Aif1
allograft inflammatory factor 1
chr2_-_110145870 3.378 NM_130452
Bbox1
butyrobetaine (gamma), 2-oxoglutarate dioxygenase 1 (gamma-butyrobetaine hydroxylase)
chr8_-_81923238 3.346 Smad1
MAD homolog 1 (Drosophila)
chr4_+_53556496 3.333 Slc44a1
solute carrier family 44, member 1
chr5_-_17341534 3.329 Cd36
CD36 antigen
chr1_-_171677653 3.275 NM_009062
Rgs4
regulator of G-protein signaling 4
chr1_+_10983542 3.233 NM_029525
Prex2
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2
chr4_-_60152702 3.212 NM_001045550
NM_008647
Mup1
Mup2

major urinary protein 1
major urinary protein 2

chr5_-_114881393 3.206


chr11_-_61058671 3.143


chr7_+_27904997 3.132 Cyp2f2
cytochrome P450, family 2, subfamily f, polypeptide 2
chr7_-_26324847 3.112 NM_001113368
NM_001113369
NM_007543
Ceacam2


carcinoembryonic antigen-related cell adhesion molecule 2


chr17_+_44090139 3.086 NM_030598
Rcan2
regulator of calcineurin 2
chr19_+_3205598 3.082


chr14_+_28051224 3.077 NM_027871
Arhgef3
Rho guanine nucleotide exchange factor (GEF) 3
chr6_+_17256415 3.066 Cav1
caveolin 1, caveolae protein
chrX_+_97963061 3.003 NM_001177778
NM_016747
Dlg3

discs, large homolog 3 (Drosophila)

chr12_-_103677867 2.892 NM_011175
Lgmn
legumain
chr6_+_122463663 2.866 NM_015776
Mfap5
microfibrillar associated protein 5
chr7_-_125849255 2.837 Gde1
glycerophosphodiester phosphodiesterase 1
chr13_+_113657736 2.815


chr16_-_26371711 2.810 NM_016674
Cldn1
claudin 1
chr13_+_42396638 2.786 NM_010104
Edn1
endothelin 1
chr14_-_124026357 2.772 NM_177393
Nalcn
sodium leak channel, non-selective
chr15_-_58010344 2.750


chr5_-_93611701 2.741


chr5_-_65844386 2.668 1110003E01Rik
RIKEN cDNA 1110003E01 gene
chr14_+_76354807 2.645 NM_026214
Kctd4
potassium channel tetramerisation domain containing 4
chr9_+_44850616 2.638 Mpzl2
myelin protein zero-like 2
chr4_+_116269256 2.623 Ccdc17
coiled-coil domain containing 17
chr19_-_20802015 2.620 NM_011921
Aldh1a7
aldehyde dehydrogenase family 1, subfamily A7
chr4_-_60736086 2.593 Mup10
Mup1
major urinary protein 10
major urinary protein 1
chr7_+_20074404 2.582 Exoc3l2
exocyst complex component 3-like 2
chr7_-_125849230 2.571 NM_019580
Gde1
glycerophosphodiester phosphodiesterase 1
chr15_-_99609351 2.561 Lima1
LIM domain and actin binding 1
chr19_+_25746900 2.560 NM_145831
Dmrt2
doublesex and mab-3 related transcription factor 2
chr17_+_44090341 2.559 Rcan2
regulator of calcineurin 2
chr5_-_93612145 2.545 Ccni
cyclin I
chr4_-_60514761 2.511 NM_001163010
NM_001163011
NM_031188
Mup1


major urinary protein 1


chr5_+_65590925 2.509 NM_153391
Wdr19
WD repeat domain 19
chr4_-_61100653 2.462 NM_001045550
NM_008647
Mup2

major urinary protein 2

chr2_-_150277200 2.459 NM_001177550
Zfp442
zinc finger protein 442
chr5_+_125048757 2.394 NM_026486
Tctn2
tectonic family member 2
chr1_-_31006599 2.367 NM_011200
Ptp4a1
protein tyrosine phosphatase 4a1
chr7_-_29965655 2.365 NM_026545
Psmd8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 8
chr19_-_34952377 2.332 NM_023792
Pank1
pantothenate kinase 1
chr12_+_37040755 2.329 NM_025312
Sostdc1
sclerostin domain containing 1
chr14_-_69151731 2.322 NM_007402
Adam7
a disintegrin and metallopeptidase domain 7
chr7_+_31337558 2.311 Hspb6
heat shock protein, alpha-crystallin-related, B6
chr16_-_32868355 2.290 NM_172615
1700021K19Rik
RIKEN cDNA 1700021K19 gene
chr16_+_25683848 2.247 NM_001127259
NM_001127260
NM_001127261
Trp63


transformation related protein 63


chr7_-_67149962 2.244 NM_013670
NM_033174
Snrpn
Snurf
small nuclear ribonucleoprotein N
SNRPN upstream reading frame
chr15_+_3230053 2.235


chrX_-_100381973 2.220 NM_008671
Nap1l2
nucleosome assembly protein 1-like 2
chr11_-_96680500 2.220 Nfe2l1
nuclear factor, erythroid derived 2,-like 1
chr8_-_42300477 2.184 Fgl1
fibrinogen-like protein 1
chr14_+_120724163 2.172 Mbnl2
muscleblind-like 2
chr12_+_109661287 2.148 Eml1
echinoderm microtubule associated protein like 1
chr11_+_76718046 2.135 NM_025655
Tmigd1
transmembrane and immunoglobulin domain containing 1
chr8_+_56040080 2.129 NM_153581
Gpm6a
glycoprotein m6a
chr16_+_92292580 2.085 NM_134110
Kcne2
potassium voltage-gated channel, Isk-related subfamily, gene 2
chr8_-_49760037 2.071 NM_001145937
NM_011857
Odz3

odd Oz/ten-m homolog 3 (Drosophila)

chr9_+_44048807 2.065 Ccdc153
coiled-coil domain containing 153
chr12_+_8928112 2.065 NM_008640
Laptm4a
lysosomal-associated protein transmembrane 4A
chr16_+_38089607 2.044 Gsk3b
glycogen synthase kinase 3 beta
chr3_-_88905775 1.986 NM_134469
Fdps
farnesyl diphosphate synthetase
chr18_+_69843730 1.982 Tcf4
transcription factor 4
chrX_+_140100287 1.961 NM_001195049
Pak3
p21 protein (Cdc42/Rac)-activated kinase 3
chr2_-_58368568 1.956 Acvr1
activin A receptor, type 1
chr9_+_44850426 1.946 NM_007962
Mpzl2
myelin protein zero-like 2
chrX_-_100381703 1.917 Nap1l2
nucleosome assembly protein 1-like 2
chr3_+_151100845 1.909 NM_133222
Eltd1
EGF, latrophilin seven transmembrane domain containing 1
chr15_+_6395311 1.903 NM_013485
C9
complement component 9
chr7_-_147268150 1.894 NM_001190386
Caly
calcyon neuron-specific vesicular protein
chr18_+_25224729 1.892 Fhod3
formin homology 2 domain containing 3
chr2_-_127555628 1.878 NM_145532
Mall
mal, T-cell differentiation protein-like
chr14_+_61386970 1.866 NM_183175
C1qtnf9
C1q and tumor necrosis factor related protein 9
chr7_-_125849167 1.858 Gde1
glycerophosphodiester phosphodiesterase 1
chr17_+_44090222 1.844 Rcan2
regulator of calcineurin 2
chr1_-_171899278 1.826 Hsd17b7
hydroxysteroid (17-beta) dehydrogenase 7
chr13_-_35118959 1.823


chr3_+_68376289 1.807 NM_013928
Schip1
schwannomin interacting protein 1
chr1_-_99873795 1.807 Pam
peptidylglycine alpha-amidating monooxygenase
chr14_+_84843366 1.768 NM_001013753
Pcdh17
protocadherin 17
chr8_-_42300504 1.747 NM_145594
Fgl1
fibrinogen-like protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.40 1.16e-02 GO:0006629 lipid metabolic process
1.84 2.56e-02 GO:0065008 regulation of biological quality
5.14 3.29e-02 GO:0030198 extracellular matrix organization
3.02 4.37e-02 GO:0090066 regulation of anatomical structure size

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.20 3.91e-03 GO:0044421 extracellular region part
2.30 1.54e-02 GO:0005615 extracellular space
1.26 2.41e-02 GO:0005737 cytoplasm
1.73 2.74e-02 GO:0005576 extracellular region

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
4.06 4.94e-02 GO:0001871 pattern binding
4.06 4.94e-02 GO:0030247 polysaccharide binding