Motif ID: GGAAUGU

Z-value: 1.474


Mature miRNA associated with seed GGAAUGU:

NamemiRBase Accession
mmu-miR-1a MIMAT0000123
mmu-miR-206 MIMAT0000239



Activity profile for motif GGAAUGU.

activity profile for motif GGAAUGU


Sorted Z-values histogram for motif GGAAUGU

Sorted Z-values for motif GGAAUGU



Network of associatons between targets according to the STRING database.



First level regulatory network of GGAAUGU

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_-_114358647 23.848 NM_011779
Coro1c
coronin, actin binding protein 1C
chr6_-_86743518 20.612 NM_013471
Anxa4
annexin A4
chr5_+_8046077 16.815 NM_025618
Sri
sorcin
chr5_-_38952777 16.311 NM_011715
Wdr1
WD repeat domain 1
chr9_+_69301471 16.080 NM_007585
Anxa2
annexin A2
chr14_+_79880952 15.615 NM_007920
Elf1
E74-like factor 1
chr7_-_152125823 15.353 NM_007631
Ccnd1
cyclin D1
chr17_-_43013320 15.332 NM_009847
Cd2ap
CD2-associated protein
chr10_+_87321789 14.941 NM_001111275
NM_010512
Igf1

insulin-like growth factor 1

chr15_-_94420206 14.710 NM_008971
Twf1
twinfilin, actin-binding protein, homolog 1 (Drosophila)
chr10_+_79317316 14.521 NM_001077363
NM_008956
Ptbp1

polypyrimidine tract binding protein 1

chr19_+_46697882 14.429 NM_001177813
D19Wsu162e
DNA segment, Chr 19, Wayne State University 162, expressed
chrX_-_71674499 14.272 NM_008062
G6pdx
glucose-6-phosphate dehydrogenase X-linked
chr8_+_74659107 14.242 NM_001001491
Tpm4
tropomyosin 4
chr18_+_53335981 13.323 NM_026386
Snx2
sorting nexin 2
chr7_+_148661138 13.200 NM_053082
Tspan4
tetraspanin 4
chr4_+_154936480 13.051 NM_138671
Nadk
NAD kinase
chr9_-_65427840 12.999 NM_153119
Plekho2
pleckstrin homology domain containing, family O member 2
chr10_-_117283020 12.336 NM_024457
Rap1b
RAS related protein 1b
chr5_+_8056508 12.181 NM_001080974
Sri
sorcin
chr6_-_99216494 11.739 NM_001197321
Foxp1
forkhead box P1
chr3_-_58329780 11.373 NM_030685
Serp1
stress-associated endoplasmic reticulum protein 1
chr6_-_98978185 11.211 NM_001197322
Foxp1
forkhead box P1
chr4_+_154937914 11.174 NM_001159637
Nadk
NAD kinase
chr3_-_104855832 10.915 NM_001163332
NM_001163333
NM_030249
Cttnbp2nl


CTTNBP2 N-terminal like


chr1_-_151808361 10.842 NM_008869
Pla2g4a
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chrX_-_163647088 10.630 NM_021278
Tmsb4x
thymosin, beta 4, X chromosome
chr4_-_133684599 10.628 NM_080559
Sh3bgrl3
SH3 domain binding glutamic acid-rich protein-like 3
chr10_+_87323855 10.368 NM_001111274
NM_001111276
NM_184052
Igf1


insulin-like growth factor 1


chr17_-_71200462 10.359 NM_009372
Tgif1
TGFB-induced factor homeobox 1
chr17_-_71202829 10.299 NM_001164074
Tgif1
TGFB-induced factor homeobox 1
chr3_-_146433200 10.129 NM_001164198
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr17_-_71196116 10.091 NM_001164077
Tgif1
TGFB-induced factor homeobox 1
chr2_+_117937623 9.823 NM_011580
Thbs1
thrombospondin 1
chr17_-_71201055 9.596 NM_001164075
Tgif1
TGFB-induced factor homeobox 1
chr17_-_71199129 9.559 NM_001164076
Tgif1
TGFB-induced factor homeobox 1
chr4_-_122563074 9.488 NM_007598
Cap1
CAP, adenylate cyclase-associated protein 1 (yeast)
chr6_-_99385338 9.479 NM_053202
Foxp1
forkhead box P1
chr18_+_44540137 9.006 NM_027490
Dcp2
DCP2 decapping enzyme homolog (S. cerevisiae)
chr15_-_38448923 8.843 NM_001102458
NM_018745
Azin1

antizyme inhibitor 1

chr1_+_174430359 8.833 NM_178598
Tagln2
transgelin 2
chr18_+_73732352 8.604 NM_001039214
Mex3c
mex3 homolog C (C. elegans)
chr19_+_41986360 8.478 NM_023418
Pgam1
phosphoglycerate mutase 1
chr3_+_95119155 8.340 NM_029789
Lass2
LAG1 homolog, ceramide synthase 2
chr2_-_84490827 8.305 NM_001085448
NM_001085449
NM_001085450
NM_007615
Ctnnd1



catenin (cadherin associated protein), delta 1



chr1_-_55144687 8.093 NM_010477
Hspd1
heat shock protein 1 (chaperonin)
chr5_+_115777174 8.085 NM_025573
Srsf9
serine/arginine-rich splicing factor 9
chr17_-_32525894 8.038 NM_011717
Wiz
widely-interspaced zinc finger motifs
chr1_-_180267913 8.007 NM_016805
Hnrnpu
heterogeneous nuclear ribonucleoprotein U
chr12_+_3806955 7.972 NM_007872
Dnmt3a
DNA methyltransferase 3A
chr8_+_109674517 7.889 NM_025558
Cyb5b
cytochrome b5 type B
chr19_+_9004106 7.850 NM_144872
Eml3
echinoderm microtubule associated protein like 3
chr11_+_97660946 7.817 NM_010688
Lasp1
LIM and SH3 protein 1
chr10_-_8605668 7.790 NM_175155
Sash1
SAM and SH3 domain containing 1
chr6_+_100783598 7.552 NM_182939
Ppp4r2
protein phosphatase 4, regulatory subunit 2
chr15_-_36724292 7.525 NM_011740
Ywhaz
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr2_-_84490666 7.499 NM_001085453
Ctnnd1
catenin (cadherin associated protein), delta 1
chr5_-_143668398 7.472 NM_007393
Actb
actin, beta
chr14_-_47809063 7.447 NM_008102
Gch1
GTP cyclohydrolase 1
chr13_-_97440734 7.324 NM_008255
Hmgcr
3-hydroxy-3-methylglutaryl-Coenzyme A reductase
chr5_-_137521896 7.257 NM_007457
Ap1s1
adaptor protein complex AP-1, sigma 1
chr10_+_17443024 7.212 NM_010828
Cited2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr12_-_78063011 7.107 NM_001146176
NM_008558
Max

Max protein

chr3_+_89876566 7.098 NM_022314
Tpm3
tropomyosin 3, gamma
chr3_-_146433544 7.055 NM_001164199
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr19_+_4148636 6.964 NM_011778
Coro1b
coronin, actin binding protein 1B
chr2_-_94278303 6.935 NM_007466
Api5
apoptosis inhibitor 5
chr9_-_61918412 6.885 NM_033320
Glce
glucuronyl C5-epimerase
chr3_+_89534639 6.796 NM_001146296
NM_019655
Adar

adenosine deaminase, RNA-specific

chr6_-_88468710 6.651 NM_016906
Sec61a1
Sec61 alpha 1 subunit (S. cerevisiae)
chr9_-_64869349 6.647 NM_021345
Ptplad1
protein tyrosine phosphatase-like A domain containing 1
chr4_+_46463917 6.605 NM_130889
Anp32b
acidic (leucine-rich) nuclear phosphoprotein 32 family, member B
chr11_+_121563691 6.563 NM_144797
Metrnl
meteorin, glial cell differentiation regulator-like
chr6_-_127100954 6.554 NM_009829
Ccnd2
cyclin D2
chr2_-_90420626 6.516 NM_008982
Ptprj
protein tyrosine phosphatase, receptor type, J
chr15_+_102236709 6.462 NM_013672
Sp1
trans-acting transcription factor 1
chr3_-_27609279 6.421 NM_173182
Fndc3b
fibronectin type III domain containing 3B
chr3_-_79371600 6.091 NM_001162999
Fnip2
folliculin interacting protein 2
chr2_+_57090045 6.062 NM_001145820
Gpd2
glycerol phosphate dehydrogenase 2, mitochondrial
chr4_-_126145660 6.024 NM_153403
Eif2c1
eukaryotic translation initiation factor 2C, 1
chr18_-_14841294 6.022 NM_001161369
NM_001161370
NM_001161371
NM_009280
Ss18



synovial sarcoma translocation, Chromosome 18



chr10_-_86168115 5.951 NM_011631
Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr8_+_130882920 5.852 NM_008737
Nrp1
neuropilin 1
chr2_-_103637096 5.763 NM_001111289
NM_001111290
NM_001111292
Caprin1


cell cycle associated protein 1


chr15_+_58247016 5.748 NM_145959
D15Ertd621e
DNA segment, Chr 15, ERATO Doi 621, expressed
chr11_+_120810346 5.693 NM_001038653
NM_001038654
Slc16a3

solute carrier family 16 (monocarboxylic acid transporters), member 3

chr15_-_50721552 5.692 NM_032000
Trps1
trichorhinophalangeal syndrome I (human)
chr2_-_169956719 5.645 NM_001033299
Zfp217
zinc finger protein 217
chr14_-_46008425 5.644 NM_019425
Gnpnat1
glucosamine-phosphate N-acetyltransferase 1
chr17_+_29627950 5.548 NM_008842
Pim1
proviral integration site 1
chr17_-_84587278 5.546 NM_001001806
Zfp36l2
zinc finger protein 36, C3H type-like 2
chr11_+_120809797 5.530 NM_030696
Slc16a3
solute carrier family 16 (monocarboxylic acid transporters), member 3
chr4_+_62021728 5.436 NM_175090
Slc31a1
solute carrier family 31, member 1
chr10_+_25128177 5.431 NM_013511
Epb4.1l2
erythrocyte protein band 4.1-like 2
chr12_-_81213930 5.394 NM_007564
Zfp36l1
zinc finger protein 36, C3H type-like 1
chr2_+_130275977 5.387 NM_001163688
NM_008980
Ptpra

protein tyrosine phosphatase, receptor type, A

chr12_+_33505175 5.340 NM_021524
Nampt
nicotinamide phosphoribosyltransferase
chr5_+_117583596 5.333 NM_001081308
Taok3
TAO kinase 3
chr1_-_133423902 5.271 NM_001081011
Srgap2
SLIT-ROBO Rho GTPase activating protein 2
chr6_+_17413930 5.263 NM_008591
Met
met proto-oncogene
chr6_-_87759747 5.238 NM_133717
Rab43
RAB43, member RAS oncogene family
chr19_+_46673553 5.164 NM_001177812
NM_146099
D19Wsu162e

DNA segment, Chr 19, Wayne State University 162, expressed

chr8_+_81033220 5.147 NM_029736
Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr12_+_101437735 5.141 NM_009790
Calm1
calmodulin 1
chr8_+_108583449 5.087 NM_010901
Nfatc3
nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 3
chr10_+_87841876 5.054 NM_001004164
Gnptab
N-acetylglucosamine-1-phosphate transferase, alpha and beta subunits
chr2_+_109516053 5.048 NM_001048139
Bdnf
brain derived neurotrophic factor
chr3_+_89518943 5.024 NM_001038587
Adar
adenosine deaminase, RNA-specific
chr4_-_133843139 4.991 NM_001163794
Pdik1l
PDLIM1 interacting kinase 1 like
chr4_+_6292817 4.938 NM_001098227
NM_016807
Sdcbp

syndecan binding protein

chr4_-_53172748 4.922 NM_013454
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr1_+_62749850 4.893 NM_001077403
NM_001077404
NM_001077405
NM_001077406
NM_001077407
NM_010939
Nrp2





neuropilin 2





chr18_+_83084023 4.853 NM_001177464
Zfp516
zinc finger protein 516
chr14_-_73109722 4.832 NM_207636
Fndc3a
fibronectin type III domain containing 3A
chr19_+_37000568 4.771 NM_001080706
Btaf1
BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, (Mot1 homolog, S. cerevisiae)
chr5_-_5380077 4.688 NM_011074
Cdk14
cyclin-dependent kinase 14
chr7_-_71083734 4.688 NM_021366
Klf13
Kruppel-like factor 13
chr15_-_93105514 4.683 NM_001033275
Gxylt1
glucoside xylosyltransferase 1
chr2_-_143836838 4.656 NM_024281
NM_133626
Rrbp1

ribosome binding protein 1

chr15_-_58913543 4.624 NM_001146180
NM_144800
Mtss1

metastasis suppressor 1

chr4_-_133843746 4.596 NM_146156
Pdik1l
PDLIM1 interacting kinase 1 like
chr11_+_87861165 4.546 NM_001078167
NM_173374
Srsf1

serine/arginine-rich splicing factor 1

chrX_-_13423666 4.507 NM_009806
Cask
calcium/calmodulin-dependent serine protein kinase (MAGUK family)
chr2_-_169968174 4.499 NM_001159683
Zfp217
zinc finger protein 217
chr2_-_180976728 4.490 NM_183162
BC006779
cDNA sequence BC006779
chr9_-_59334089 4.489 NM_019927
Arih1
ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)
chr7_-_140206929 4.357 NM_001170744
Ctbp2
C-terminal binding protein 2
chr18_+_83080270 4.251 NM_183033
Zfp516
zinc finger protein 516
chr8_+_71612616 4.228 NM_007509
Atp6v1b2
ATPase, H+ transporting, lysosomal V1 subunit B2
chr14_-_51550327 4.178 NM_001033271
Tmem55b
transmembrane protein 55b
chr1_-_46910333 4.138 NM_172653
Slc39a10
solute carrier family 39 (zinc transporter), member 10
chr16_+_4594703 4.120 NM_031184
Glis2
GLIS family zinc finger 2
chr2_+_162843196 4.072 NM_172150
Ift52
intraflagellar transport 52 homolog (Chlamydomonas)
chr9_-_21918612 4.056 NM_170777
Elof1
elongation factor 1 homolog (ELF1, S. cerevisiae)
chr16_+_27388907 4.053 NM_001025615
NM_026202
Ccdc50

coiled-coil domain containing 50

chr18_+_56722222 3.996 NM_001162989
Phax
phosphorylated adaptor for RNA export
chr3_+_27883092 3.995 NM_008875
Pld1
phospholipase D1
chrX_+_7339786 3.989 NM_001105196
NM_172472
Tcfe3

transcription factor E3

chr11_+_35582969 3.946 NM_145962
Pank3
pantothenate kinase 3
chr6_-_35489875 3.913 NM_008098
Mtpn
myotrophin
chr1_+_55144949 3.913 NM_008303
Hspe1
heat shock protein 1 (chaperonin 10)
chr2_+_156665812 3.903 NM_173396
Tgif2
TGFB-induced factor homeobox 2
chr3_-_89018256 3.899 NM_001161824
NM_013604
Mtx1

metaxin 1

chr1_-_174136874 3.896 NM_011063
Pea15a
phosphoprotein enriched in astrocytes 15A
chr12_-_60320438 3.880 NM_001033156
Fbxo33
F-box protein 33
chr9_-_70351520 3.869 NM_033604
Rnf111
ring finger 111
chr2_-_103637795 3.858 NM_001111291
NM_016739
Caprin1

cell cycle associated protein 1

chr15_-_80935436 3.827 NM_153049
Mkl1
MKL (megakaryoblastic leukemia)/myocardin-like 1
chr11_+_29072836 3.821 NM_134034
Smek2
SMEK homolog 2, suppressor of mek1 (Dictyostelium)
chr9_-_56265833 3.816 NM_172924
C230081A13Rik
RIKEN cDNA C230081A13 gene
chr15_+_103070840 3.760 NM_001039129
NM_010447
Hnrnpa1

heterogeneous nuclear ribonucleoprotein A1

chr1_+_191552133 3.740 NM_008976
Ptpn14
protein tyrosine phosphatase, non-receptor type 14
chr15_-_81021165 3.723 NM_001082536
Mkl1
MKL (megakaryoblastic leukemia)/myocardin-like 1
chr7_-_96487247 3.713 NM_028343
Tmem135
transmembrane protein 135
chr17_-_87846158 3.700 NM_007589
Calm2
calmodulin 2
chr1_+_88423310 3.690 NM_008972
Ptma
prothymosin alpha
chr3_-_19211000 3.687 NM_001122759
Pde7a
phosphodiesterase 7A
chr15_-_98593505 3.671 NM_007478
Arf3
ADP-ribosylation factor 3
chr10_+_82448214 3.623 NM_021439
Chst11
carbohydrate sulfotransferase 11
chr13_+_76522408 3.615 NM_030174
Mctp1
multiple C2 domains, transmembrane 1
chrX_+_12164878 3.608 NM_027439
Atp6ap2
ATPase, H+ transporting, lysosomal accessory protein 2
chrX_-_90877453 3.576 NM_008892
Pola1
polymerase (DNA directed), alpha 1
chrX_-_101609169 3.557 NM_009592
Abcb7
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr2_-_91790504 3.545 NM_001166597
Dgkz
diacylglycerol kinase zeta
chr13_+_113254277 3.514 NM_010560
Il6st
interleukin 6 signal transducer
chr18_-_3281709 3.486 NM_001110854
NM_001110855
Crem

cAMP responsive element modulator

chr10_+_89207730 3.481 NM_029166
Uhrf1bp1l
UHRF1 (ICBP90) binding protein 1-like
chr14_+_27457610 3.480 NM_007479
Arf4
ADP-ribosylation factor 4
chr4_-_26273772 3.465 NM_172865
Manea
mannosidase, endo-alpha
chr6_+_126889979 3.425 NM_138594
D6Wsu163e
DNA segment, Chr 6, Wayne State University 163, expressed
chr7_-_121398132 3.400 NM_033370
Copb1
coatomer protein complex, subunit beta 1
chr17_-_57170896 3.378 NM_010613
Khsrp
KH-type splicing regulatory protein
chr8_-_112261607 3.366 NM_001080930
Atxn1l
ataxin 1-like
chr15_+_84753817 3.343 NM_016714
Nup50
nucleoporin 50
chrX_+_12858142 3.301 NM_010028
Ddx3x
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 3, X-linked
chr5_-_114830457 3.298 NM_001159941
NM_026145
Kctd10

potassium channel tetramerisation domain containing 10

chr8_+_87561055 3.255 NM_001122843
Tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr3_-_146444377 3.243 NM_001164200
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr7_-_123586952 3.239 NM_011083
Pik3c2a
phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide
chr8_+_112392441 3.229 NM_001122594
Phlpp2
PH domain and leucine rich repeat protein phosphatase 2
chr2_-_166539288 3.177 NM_177782
Prex1
phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
chr6_-_30193802 3.113 NM_001169577
Ube2h
ubiquitin-conjugating enzyme E2H
chr7_+_133903118 3.110 NM_011952
Mapk3
mitogen-activated protein kinase 3
chr12_+_72932064 3.050 NM_026102
NM_172464
Daam1

dishevelled associated activator of morphogenesis 1

chrX_+_39502588 3.041 NM_001077712
Stag2
stromal antigen 2
chr2_+_109731003 3.027 NM_011699
Lin7c
lin-7 homolog C (C. elegans)
chrX_+_138662725 3.019 NM_172782
Nxt2
nuclear transport factor 2-like export factor 2
chr2_+_109514856 3.015 NM_007540
Bdnf
brain derived neurotrophic factor
chr4_-_128925666 3.007 NM_001033189
C77080
expressed sequence C77080
chr1_+_157005804 3.007 NM_021433
Stx6
syntaxin 6
chr1_+_187156018 3.007 NM_011794
Bpnt1
bisphosphate 3'-nucleotidase 1
chr16_-_17928270 2.968 NM_153150
Slc25a1
solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
chr7_-_133343904 2.967 NM_028816
Xpo6
exportin 6
chr8_-_8660610 2.928 NM_010111
Efnb2
ephrin B2
chr3_-_105604199 2.878 NM_145541
Rap1a
RAS-related protein-1a
chr2_-_165710128 2.873 NM_027230
Zmynd8
zinc finger, MYND-type containing 8
chr3_-_78949796 2.872 NM_001099624
Rapgef2
Rap guanine nucleotide exchange factor (GEF) 2
chr10_-_75384293 2.864 NM_001161853
NM_011418
Smarcb1

SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1

chr2_+_181255209 2.756 NM_016775
Dnajc5
DnaJ (Hsp40) homolog, subfamily C, member 5
chr7_+_46843887 2.729 NM_001170345
Gm2058
predicted gene 2058

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.04 1.80e-14 GO:0019222 regulation of metabolic process
2.09 2.34e-13 GO:0080090 regulation of primary metabolic process
2.11 3.58e-13 GO:0060255 regulation of macromolecule metabolic process
2.08 4.06e-13 GO:0031323 regulation of cellular metabolic process
1.69 9.84e-13 GO:0044237 cellular metabolic process
1.35 1.70e-11 GO:0009987 cellular process
2.20 3.53e-11 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.18 6.75e-11 GO:0051171 regulation of nitrogen compound metabolic process
2.19 8.97e-11 GO:0010468 regulation of gene expression
1.63 1.06e-10 GO:0044238 primary metabolic process
2.04 1.96e-10 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.79 2.51e-10 GO:0044260 cellular macromolecule metabolic process
2.17 7.31e-10 GO:0010556 regulation of macromolecule biosynthetic process
2.17 1.27e-09 GO:2000112 regulation of cellular macromolecule biosynthetic process
1.92 1.31e-09 GO:0006807 nitrogen compound metabolic process
2.09 2.13e-09 GO:0009889 regulation of biosynthetic process
2.09 2.64e-09 GO:0031326 regulation of cellular biosynthetic process
1.92 3.30e-09 GO:0034641 cellular nitrogen compound metabolic process
2.18 8.06e-09 GO:0016070 RNA metabolic process
2.16 1.28e-08 GO:0051252 regulation of RNA metabolic process
1.66 3.03e-08 GO:0043170 macromolecule metabolic process
2.09 3.30e-08 GO:0048522 positive regulation of cellular process
1.50 3.43e-08 GO:0008152 metabolic process
2.60 9.41e-08 GO:0031325 positive regulation of cellular metabolic process
2.53 1.16e-07 GO:0009893 positive regulation of metabolic process
2.10 2.06e-07 GO:0006355 regulation of transcription, DNA-dependent
1.98 2.91e-07 GO:0090304 nucleic acid metabolic process
1.95 5.15e-07 GO:0048518 positive regulation of biological process
2.81 8.72e-07 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.80 9.33e-07 GO:0009891 positive regulation of biosynthetic process
2.50 1.26e-06 GO:0010604 positive regulation of macromolecule metabolic process
2.24 1.36e-06 GO:0032774 RNA biosynthetic process
2.79 1.65e-06 GO:0031328 positive regulation of cellular biosynthetic process
2.86 2.03e-06 GO:0010557 positive regulation of macromolecule biosynthetic process
2.01 2.72e-06 GO:0048519 negative regulation of biological process
3.64 3.25e-06 GO:0060548 negative regulation of cell death
2.21 3.29e-06 GO:0006351 transcription, DNA-dependent
2.06 3.89e-06 GO:0048523 negative regulation of cellular process
3.67 5.40e-06 GO:0043069 negative regulation of programmed cell death
2.38 6.88e-06 GO:0009653 anatomical structure morphogenesis
1.82 7.89e-06 GO:0044249 cellular biosynthetic process
2.83 1.15e-05 GO:0010628 positive regulation of gene expression
1.94 1.50e-05 GO:0048731 system development
1.79 1.57e-05 GO:0009058 biosynthetic process
1.78 1.58e-05 GO:0032502 developmental process
3.58 1.68e-05 GO:0043066 negative regulation of apoptosis
1.40 2.18e-05 GO:0050794 regulation of cellular process
1.89 2.27e-05 GO:0010467 gene expression
2.86 2.33e-05 GO:0015031 protein transport
5.76 2.95e-05 GO:0006916 anti-apoptosis
2.79 4.15e-05 GO:0045184 establishment of protein localization
2.85 4.22e-05 GO:0045893 positive regulation of transcription, DNA-dependent
1.37 5.26e-05 GO:0050789 regulation of biological process
2.80 6.13e-05 GO:0051254 positive regulation of RNA metabolic process
1.83 6.87e-05 GO:0048856 anatomical structure development
1.88 1.04e-04 GO:0009059 macromolecule biosynthetic process
3.11 1.06e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.77 1.15e-04 GO:0007275 multicellular organismal development
2.62 1.34e-04 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.79 1.54e-04 GO:0016071 mRNA metabolic process
1.87 1.63e-04 GO:0034645 cellular macromolecule biosynthetic process
2.05 1.73e-04 GO:0048513 organ development
1.34 2.18e-04 GO:0065007 biological regulation
2.56 2.49e-04 GO:0051173 positive regulation of nitrogen compound metabolic process
2.30 3.38e-04 GO:0033036 macromolecule localization
3.03 8.67e-04 GO:0008284 positive regulation of cell proliferation
2.72 1.10e-03 GO:0010629 negative regulation of gene expression
2.03 1.20e-03 GO:0048583 regulation of response to stimulus
2.34 1.48e-03 GO:0008104 protein localization
1.66 1.49e-03 GO:0051179 localization
4.05 1.73e-03 GO:0010608 posttranscriptional regulation of gene expression
2.20 2.00e-03 GO:0009966 regulation of signal transduction
2.33 2.30e-03 GO:0010605 negative regulation of macromolecule metabolic process
3.58 2.60e-03 GO:0051270 regulation of cellular component movement
3.54 3.14e-03 GO:0040012 regulation of locomotion
3.52 3.45e-03 GO:0001944 vasculature development
2.74 3.51e-03 GO:0046907 intracellular transport
2.57 3.64e-03 GO:0010558 negative regulation of macromolecule biosynthetic process
2.39 3.71e-03 GO:0009888 tissue development
2.51 4.02e-03 GO:0009890 negative regulation of biosynthetic process
2.58 4.78e-03 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
2.47 5.62e-03 GO:0045595 regulation of cell differentiation
2.21 5.74e-03 GO:0009892 negative regulation of metabolic process
2.23 6.53e-03 GO:0050793 regulation of developmental process
2.85 6.67e-03 GO:0072358 cardiovascular system development
2.85 6.67e-03 GO:0072359 circulatory system development
2.48 7.02e-03 GO:0031327 negative regulation of cellular biosynthetic process
2.32 7.37e-03 GO:0042127 regulation of cell proliferation
2.26 8.78e-03 GO:0032268 regulation of cellular protein metabolic process
3.56 9.92e-03 GO:0006397 mRNA processing
3.52 1.14e-02 GO:0030334 regulation of cell migration
2.33 1.21e-02 GO:0051649 establishment of localization in cell
2.20 1.23e-02 GO:0010941 regulation of cell death
1.67 1.25e-02 GO:0006810 transport
3.48 1.37e-02 GO:2000145 regulation of cell motility
2.57 1.71e-02 GO:0009887 organ morphogenesis
2.19 1.72e-02 GO:0043067 regulation of programmed cell death
3.27 1.73e-02 GO:0006886 intracellular protein transport
1.64 2.21e-02 GO:0051234 establishment of localization
3.68 2.33e-02 GO:0048514 blood vessel morphogenesis
3.07 2.40e-02 GO:0048729 tissue morphogenesis
2.12 2.61e-02 GO:0051246 regulation of protein metabolic process
2.43 3.02e-02 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.66 3.16e-02 GO:0051094 positive regulation of developmental process
2.15 3.36e-02 GO:0031324 negative regulation of cellular metabolic process
2.52 3.56e-02 GO:0045892 negative regulation of transcription, DNA-dependent
5.80 3.63e-02 GO:0045787 positive regulation of cell cycle
1.91 3.92e-02 GO:0023051 regulation of signaling
2.40 3.94e-02 GO:0051172 negative regulation of nitrogen compound metabolic process
2.45 3.99e-02 GO:0019220 regulation of phosphate metabolic process
2.45 3.99e-02 GO:0051174 regulation of phosphorus metabolic process
2.48 4.58e-02 GO:0051253 negative regulation of RNA metabolic process
3.04 4.67e-02 GO:0007167 enzyme linked receptor protein signaling pathway

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.58 7.35e-28 GO:0044424 intracellular part
1.56 3.51e-27 GO:0005622 intracellular
1.64 1.28e-23 GO:0043226 organelle
1.64 2.57e-23 GO:0043229 intracellular organelle
1.63 3.28e-18 GO:0043227 membrane-bounded organelle
1.63 6.82e-18 GO:0043231 intracellular membrane-bounded organelle
1.89 2.58e-15 GO:0005634 nucleus
1.25 9.05e-14 GO:0005623 cell
1.25 9.05e-14 GO:0044464 cell part
1.54 1.88e-12 GO:0005737 cytoplasm
1.69 3.66e-07 GO:0044422 organelle part
1.68 1.04e-06 GO:0044446 intracellular organelle part
2.15 1.50e-06 GO:0044428 nuclear part
1.72 1.29e-05 GO:0032991 macromolecular complex
2.17 2.44e-05 GO:0005829 cytosol
1.76 6.52e-05 GO:0043234 protein complex
2.27 7.51e-05 GO:0000267 cell fraction
2.08 1.94e-04 GO:0031981 nuclear lumen
2.25 8.57e-04 GO:0005654 nucleoplasm
1.42 9.42e-04 GO:0044444 cytoplasmic part
2.24 2.41e-03 GO:0005626 insoluble fraction
1.84 4.50e-03 GO:0070013 intracellular organelle lumen
1.84 4.73e-03 GO:0043233 organelle lumen
1.80 8.05e-03 GO:0031974 membrane-enclosed lumen
3.01 8.27e-03 GO:0005625 soluble fraction
2.07 3.36e-02 GO:0005624 membrane fraction
1.58 3.75e-02 GO:0043228 non-membrane-bounded organelle
1.58 3.75e-02 GO:0043232 intracellular non-membrane-bounded organelle
3.71 4.67e-02 GO:0031252 cell leading edge

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.48 2.70e-18 GO:0005488 binding
1.70 1.67e-11 GO:0005515 protein binding
2.12 7.36e-10 GO:0003676 nucleic acid binding
2.29 4.26e-08 GO:0003677 DNA binding
2.65 1.12e-04 GO:0001071 nucleic acid binding transcription factor activity
2.65 1.12e-04 GO:0003700 sequence-specific DNA binding transcription factor activity
2.78 1.37e-04 GO:0043565 sequence-specific DNA binding
1.86 1.63e-04 GO:0000166 nucleotide binding
2.42 5.30e-04 GO:0019899 enzyme binding
2.03 1.42e-03 GO:0008270 zinc ion binding
1.92 1.52e-03 GO:0046914 transition metal ion binding
2.48 2.09e-03 GO:0003723 RNA binding
2.21 5.38e-03 GO:0030528 transcription regulator activity
5.87 6.52e-03 GO:0047485 protein N-terminus binding
2.55 1.81e-02 GO:0008092 cytoskeletal protein binding
3.63 1.93e-02 GO:0000975 regulatory region DNA binding
3.63 1.93e-02 GO:0001067 regulatory region nucleic acid binding
3.63 1.93e-02 GO:0044212 transcription regulatory region DNA binding
3.00 2.88e-02 GO:0016564 transcription repressor activity
2.21 4.26e-02 GO:0046983 protein dimerization activity
3.57 4.26e-02 GO:0010843 promoter binding