Motif ID: GLI1..3.p2

Z-value: 1.522


Transcription factors associated with GLI1..3.p2:

Gene SymbolEntrez IDGene Name
Gli1 14632 GLI-Kruppel family member GLI1
Gli2 14633 GLI-Kruppel family member GLI2
Gli3 14634 GLI-Kruppel family member GLI3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gli2chr1_-_1209501110.231.5e-03Click!
Gli3chr13_+_155554830.222.7e-03Click!
Gli1chr10_-_126778634-0.083.1e-01Click!


Activity profile for motif GLI1..3.p2.

activity profile for motif GLI1..3.p2


Sorted Z-values histogram for motif GLI1..3.p2

Sorted Z-values for motif GLI1..3.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GLI1..3.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr17_+_37182910 30.573 NM_019439
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr8_+_56040193 26.057 Gpm6a
glycoprotein m6a
chr8_+_56040211 25.232 Gpm6a
glycoprotein m6a
chr8_+_56040553 23.678 Gpm6a
glycoprotein m6a
chr8_+_56040445 23.037 Gpm6a
glycoprotein m6a
chr8_+_56040080 22.776 NM_153581
Gpm6a
glycoprotein m6a
chr9_+_43875175 20.454 Usp2
ubiquitin specific peptidase 2
chr13_-_100286521 19.966 NM_008634
Mtap1b
microtubule-associated protein 1B
chr8_-_67171481 19.427 Cpe
carboxypeptidase E
chr7_-_82453216 19.062 NM_001109753
Sv2b
synaptic vesicle glycoprotein 2 b
chr8_-_67171692 18.864 Cpe
carboxypeptidase E
chr13_-_100286446 18.714 Mtap1b
microtubule-associated protein 1B
chr8_-_67171805 18.708 NM_013494
Cpe
carboxypeptidase E
chr9_+_43875103 18.139 NM_198092
Usp2
ubiquitin specific peptidase 2
chr1_-_137063881 17.999 Gpr37l1
G protein-coupled receptor 37-like 1
chr7_+_138122822 17.466 Htra1
HtrA serine peptidase 1
chr2_+_157385835 17.178 NM_010923
NM_180960
Nnat

neuronatin

chr13_-_78337844 17.102 Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr12_+_45429966 17.035 Nrcam
neuron-glia-CAM-related cell adhesion molecule
chr12_+_45429913 16.790 Nrcam
neuron-glia-CAM-related cell adhesion molecule
chr1_-_137064124 16.373 NM_134438
Gpr37l1
G protein-coupled receptor 37-like 1
chr10_-_61573705 16.228 NM_027251
2010107G23Rik
RIKEN cDNA 2010107G23 gene
chr19_-_5085487 15.647 Tmem151a
transmembrane protein 151A
chr7_-_82453166 15.580 Sv2b
synaptic vesicle glycoprotein 2 b
chr4_-_150482562 15.165 Camta1
calmodulin binding transcription activator 1
chr13_+_48356487 15.115 Id4
inhibitor of DNA binding 4
chr8_+_46744023 15.080 Sorbs2
sorbin and SH3 domain containing 2
chr13_+_48356795 14.916 NM_031166
Id4
inhibitor of DNA binding 4
chr11_-_41995688 14.835 Gabra1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr4_-_68615283 14.669 Dbc1
deleted in bladder cancer 1 (human)
chr16_+_18777032 14.654 Cldn5
claudin 5
chr11_-_41813792 14.530 NM_177408
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr15_+_91881593 14.517 NM_001159648
Cntn1
contactin 1
chr9_-_54509453 14.516 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr4_-_68615382 14.248 NM_019967
Dbc1
deleted in bladder cancer 1 (human)
chr9_-_54509658 14.190 NM_053178
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr1_-_175266945 14.146 Cadm3
cell adhesion molecule 3
chr13_+_46597271 14.082 NM_026056
Cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr16_-_28445276 13.584 NM_183064
Fgf12
fibroblast growth factor 12
chr11_+_68505612 13.321 Myh10
myosin, heavy polypeptide 10, non-muscle
chr7_-_74879894 13.262 Synm
synemin, intermediate filament protein
chr3_-_117063090 13.197 D3Bwg0562e
DNA segment, Chr 3, Brigham & Women's Genetics 0562 expressed
chr11_+_68505616 13.164 Myh10
myosin, heavy polypeptide 10, non-muscle
chr19_+_4711207 13.155 Spnb3
spectrin beta 3
chr13_+_46597461 13.124 Cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr4_-_4065585 13.026 NM_001002927
Penk
preproenkephalin
chr9_+_109834266 13.008 NM_008633
Mtap4
microtubule-associated protein 4
chr12_+_45429857 12.954 NM_001146031
NM_176930
Nrcam

neuron-glia-CAM-related cell adhesion molecule

chr12_+_75098739 12.617 NM_172804
Syt16
synaptotagmin XVI
chr2_-_80421054 12.585 NM_016965
Nckap1
NCK-associated protein 1
chr19_-_5085471 12.454 NM_001001885
Tmem151a
transmembrane protein 151A
chr7_-_88599560 12.375 NM_007755
Cpeb1
cytoplasmic polyadenylation element binding protein 1
chr2_+_28048511 12.297 Olfm1
olfactomedin 1
chr10_-_126700387 12.280 NM_001039000
NM_008447
Kif5a

kinesin family member 5A

chr4_-_4065205 12.233 Penk
preproenkephalin
chr13_+_46597448 12.121 Cap2
CAP, adenylate cyclase-associated protein, 2 (yeast)
chr9_+_109834324 11.978 Mtap4
microtubule-associated protein 4
chr7_+_25266986 11.870 NM_153112
Cadm4
cell adhesion molecule 4
chr2_+_49474775 11.690 NM_008449
Kif5c
kinesin family member 5C
chr12_-_112910475 11.678 NM_021273
Ckb
creatine kinase, brain
chr11_+_101107635 11.658 NM_019444
Ramp2
receptor (calcitonin) activity modifying protein 2
chr16_+_18776936 11.599 NM_013805
Cldn5
claudin 5
chr3_-_26230791 11.407 NM_138666
Nlgn1
neuroligin 1
chr10_+_68996455 11.403 NM_146005
NM_170688
NM_170689
NM_170690
NM_170728
NM_170729
NM_170730
Ank3






ankyrin 3, epithelial






chr7_-_52625929 11.322 NM_011698
Lin7b
lin-7 homolog B (C. elegans)
chr16_+_5884885 11.284 NM_021477
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr1_+_154802091 11.284 Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr3_+_68298129 11.262 Schip1
schwannomin interacting protein 1
chr2_+_49474840 11.241 Kif5c
kinesin family member 5C
chr4_+_43644806 11.061 NM_173788
Npr2
natriuretic peptide receptor 2
chr16_+_18776955 10.939 Cldn5
claudin 5
chr7_+_89319681 10.922 Sh3gl3
SH3-domain GRB2-like 3
chr12_+_3365295 10.857 Kif3c
kinesin family member 3C
chr5_+_89316245 10.678 NM_001136260
NM_001197147
NM_018760
Slc4a4


solute carrier family 4 (anion exchanger), member 4


chr11_-_41814008 10.637 NM_008073
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr11_+_68505416 10.617 NM_175260
Myh10
myosin, heavy polypeptide 10, non-muscle
chr6_-_124719465 10.601 NM_013509
Eno2
enolase 2, gamma neuronal
chr4_-_58566053 10.554 NM_172989
Lpar1
lysophosphatidic acid receptor 1
chr2_+_106533281 10.550 Mpped2
metallophosphoesterase domain containing 2
chr16_+_5885447 10.503 Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chrX_-_70905384 10.453 Pnck
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr19_+_4711220 10.448 NM_021287
Spnb3
spectrin beta 3
chr12_-_71448300 10.365 Trim9
tripartite motif-containing 9
chr1_+_50984361 10.312 NM_019790
Tmeff2
transmembrane protein with EGF-like and two follistatin-like domains 2
chr11_+_78312784 10.310 Vtn
vitronectin
chr9_+_43893029 10.304 Usp2
ubiquitin specific peptidase 2
chr13_+_93195850 10.172 NM_175455
Ankrd34b
ankyrin repeat domain 34B
chr6_+_107479719 10.149 NM_008516
Lrrn1
leucine rich repeat protein 1, neuronal
chr2_-_25324650 10.123 Ptgds
prostaglandin D2 synthase (brain)
chr2_+_157387284 10.069 Nnat
neuronatin
chrX_-_70905062 10.035 NM_012040
Pnck
pregnancy upregulated non-ubiquitously expressed CaM kinase
chr9_+_50560862 9.988 NM_009964
Cryab
crystallin, alpha B
chr18_-_70301202 9.946 NM_001082553
Rab27b
RAB27b, member RAS oncogene family
chr4_+_42929523 9.877 N28178
expressed sequence N28178
chr1_+_155747072 9.832 NM_008131
Glul
glutamate-ammonia ligase (glutamine synthetase)
chr15_-_94234778 9.829 NM_001164785
NM_001164786
NM_177431
Adamts20


a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 20


chr1_+_75542840 9.805 NM_009208
Slc4a3
solute carrier family 4 (anion exchanger), member 3
chr2_+_106533615 9.778 NM_001143683
Mpped2
metallophosphoesterase domain containing 2
chr6_+_124959207 9.763 Zfp384
zinc finger protein 384
chr4_-_154273134 9.710 NM_025582
2810405K02Rik
RIKEN cDNA 2810405K02 gene
chrX_+_78316003 9.547 Tmem47
transmembrane protein 47
chr9_+_106366204 9.465


chr4_-_58566362 9.424 NM_010336
Lpar1
lysophosphatidic acid receptor 1
chr7_-_125591493 9.343 Syt17
synaptotagmin XVII
chr17_+_27792587 9.242 NM_011861
Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr5_+_130924661 9.215 NM_021371
Caln1
calneuron 1
chr3_+_115710360 9.203 NM_001163515
NM_021388
Extl2

exostoses (multiple)-like 2

chr2_+_164312023 9.004 Dbndd2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr11_+_101107726 8.936 Ramp2
receptor (calcitonin) activity modifying protein 2
chr7_+_89319717 8.873 NM_017400
Sh3gl3
SH3-domain GRB2-like 3
chr7_-_125587065 8.780 NM_138649
Syt17
synaptotagmin XVII
chr2_+_90729768 8.763 C1qtnf4
C1q and tumor necrosis factor related protein 4
chr6_+_41555460 8.682 NM_001146351
NM_007680
Ephb6

Eph receptor B6

chr5_-_133018212 8.647 NM_177047
Auts2
autism susceptibility candidate 2
chr4_-_86876328 8.565 NM_172426
Slc24a2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr13_-_78338131 8.541 NM_010151
Nr2f1
nuclear receptor subfamily 2, group F, member 1
chr12_+_30687597 8.402 Pxdn
peroxidasin homolog (Drosophila)
chr11_-_4847968 8.332 NM_010904
Nefh
neurofilament, heavy polypeptide
chr7_+_53693190 8.309 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chrX_-_91787338 8.280 Maged1
melanoma antigen, family D, 1
chr14_-_21613162 8.141 NM_001039138
NM_001039139
NM_178597
Camk2g


calcium/calmodulin-dependent protein kinase II gamma


chr2_-_151458299 8.095 Snph
syntaphilin
chr3_+_7503409 8.066 NM_173181
Fam164a
family with sequence similarity 164, member A
chr17_-_24826873 8.038 NM_011522
Syngr3
synaptogyrin 3
chrX_+_78315963 8.027 NM_138751
Tmem47
transmembrane protein 47
chr9_-_103125934 8.021 Trf
transferrin
chr2_-_53937785 8.019 NM_023396
Rprm
reprimo, TP53 dependent G2 arrest mediator candidate
chr6_+_108163089 8.010 NM_010585
Itpr1
inositol 1,4,5-triphosphate receptor 1
chr2_+_169459145 7.982 NM_080455
Tshz2
teashirt zinc finger family member 2
chr6_+_117961386 7.977 Rasgef1a
RasGEF domain family, member 1A
chr14_+_70930768 7.969 Lgi3
leucine-rich repeat LGI family, member 3
chr2_-_91771919 7.963 NM_001012336
Mdk
midkine
chr14_+_70930491 7.959 NM_145219
Lgi3
leucine-rich repeat LGI family, member 3
chr9_+_43892984 7.926 NM_198091
Usp2
ubiquitin specific peptidase 2
chr2_-_91771836 7.830 NM_001012335
Mdk
midkine
chr2_-_91771882 7.774 Mdk
midkine
chr3_+_90341208 7.704 S100a16
S100 calcium binding protein A16
chrX_-_91787317 7.702 Maged1
melanoma antigen, family D, 1
chr7_+_31844947 7.702 NM_144556
Lgi4
leucine-rich repeat LGI family, member 4
chr5_+_34064954 7.650 NM_001163216
NM_001163217
Fgfr3

fibroblast growth factor receptor 3

chr6_+_30688050 7.628 NM_008590
Mest
mesoderm specific transcript
chr11_-_119903061 7.521 NM_001198787
Aatk
apoptosis-associated tyrosine kinase
chr1_-_166387998 7.451 Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr17_+_27792487 7.433 Pacsin1
protein kinase C and casein kinase substrate in neurons 1
chr1_+_154802144 7.413 Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr2_-_92274110 7.404 NM_001113333
NM_009963
Cry2

cryptochrome 2 (photolyase-like)

chr18_+_40416615 7.400 2900055J20Rik
RIKEN cDNA 2900055J20 gene
chrX_-_91787353 7.327 Maged1
melanoma antigen, family D, 1
chr15_-_95359136 7.306 NM_016743
Nell2
NEL-like 2 (chicken)
chr7_+_52960585 7.184 NM_016974
Dbp
D site albumin promoter binding protein
chr3_+_45182311 7.167 NM_001098170
NM_001098171
NM_001098172
NM_011043
Pcdh10



protocadherin 10



chr6_-_88824037 7.157 NM_176973
Podxl2
podocalyxin-like 2
chr7_-_6683113 7.060 NM_008817
Peg3
paternally expressed 3
chr3_+_62142698 6.999 NM_001081295
Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr7_+_64846558 6.978 Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr5_-_8622882 6.975 NM_198620
Rundc3b
RUN domain containing 3B
chr7_+_134094045 6.911 NM_144926
Sez6l2
seizure related 6 homolog like 2
chr7_-_126127713 6.747 Gprc5b
G protein-coupled receptor, family C, group 5, member B
chr14_+_60997104 6.676 NM_001164705
NM_028113
Fam123a

family with sequence similarity 123, member A

chr13_-_92901406 6.670 NM_009027
Rasgrf2
RAS protein-specific guanine nucleotide-releasing factor 2
chr17_-_25036364 6.622 Mapk8ip3
mitogen-activated protein kinase 8 interacting protein 3
chr6_-_115201866 6.600 NM_080639
Timp4
tissue inhibitor of metalloproteinase 4
chr7_+_52960702 6.586 Dbp
D site albumin promoter binding protein
chrX_-_91787351 6.579 Maged1
melanoma antigen, family D, 1
chr17_+_25707771 6.572 2810468N07Rik
RIKEN cDNA 2810468N07 gene
chr4_+_117507993 6.560 Slc6a9
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr5_-_118694869 6.488 NM_172998
NM_001109902
Rnft2

ring finger protein, transmembrane 2

chr1_+_12682510 6.470 NM_001198565
NM_001198566
Sulf1

sulfatase 1

chr2_+_164312087 6.470 Dbndd2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr1_-_95532227 6.460 Stk25
serine/threonine kinase 25 (yeast)
chr7_-_25857275 6.449 NM_008168
Grik5
glutamate receptor, ionotropic, kainate 5 (gamma 2)
chr9_+_108192759 6.439 NM_025449
Nicn1
nicolin 1
chr2_-_151458256 6.381 NM_198214
Snph
syntaphilin
chr1_-_95532270 6.355 Stk25
serine/threonine kinase 25 (yeast)
chr1_-_95532192 6.322 Stk25
serine/threonine kinase 25 (yeast)
chr11_-_78059124 6.315 NM_009297
Supt6h
suppressor of Ty 6 homolog (S. cerevisiae)
chr9_-_45714487 6.305 Rnf214
ring finger protein 214
chr14_-_37911383 6.168 NM_130878
Cdhr1
cadherin-related family member 1
chrX_+_97963061 6.147 NM_001177778
NM_016747
Dlg3

discs, large homolog 3 (Drosophila)

chr17_-_24826812 6.144 Syngr3
synaptogyrin 3
chr2_+_164312376 6.101 NM_001048228
Dbndd2
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr9_-_83699706 6.098 NM_001145974
NM_148941
Elovl4

elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 4

chr1_-_95532242 6.083 Stk25
serine/threonine kinase 25 (yeast)
chr4_-_128798939 6.082 NM_001130419
Hpca
hippocalcin
chr9_+_120213190 6.068 NM_144557
Myrip
myosin VIIA and Rab interacting protein
chr9_+_69137659 6.063 Rora
RAR-related orphan receptor alpha
chr8_+_121970569 6.007 NM_054095
Necab2
N-terminal EF-hand calcium binding protein 2
chr17_+_25864702 6.006 Rpusd1
RNA pseudouridylate synthase domain containing 1
chr18_+_37303622 5.999 NM_001003672
Pcdhac2
protocadherin alpha subfamily C, 2
chr9_+_110148568 5.994 Cspg5
chondroitin sulfate proteoglycan 5
chr15_-_75397243 5.974 NM_001135688
Ly6h
lymphocyte antigen 6 complex, locus H
chr1_+_154802198 5.959 NM_175460
Nmnat2
nicotinamide nucleotide adenylyltransferase 2
chr1_-_95531961 5.876 Stk25
serine/threonine kinase 25 (yeast)
chr7_-_149558139 5.876 NM_177265
6330512M04Rik
RIKEN cDNA 6330512M04 gene
chr9_-_79641131 5.862 Tmem30a
transmembrane protein 30A
chr1_-_95532278 5.843 NM_021537
Stk25
serine/threonine kinase 25 (yeast)
chr4_-_128798481 5.815 NM_010471
Hpca
hippocalcin
chr9_-_103118185 5.808 Trf
transferrin
chr11_+_115281434 5.804 NM_183285
Kctd2
potassium channel tetramerisation domain containing 2
chr9_-_108363229 5.787 Klhdc8b
kelch domain containing 8B

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.73 9.25e-07 GO:0032879 regulation of localization
1.59 1.56e-06 GO:0023051 regulation of signaling
2.30 4.85e-06 GO:0019226 transmission of nerve impulse
2.30 4.85e-06 GO:0035637 multicellular organismal signaling
1.63 1.01e-05 GO:0007399 nervous system development
1.35 1.08e-05 GO:0032502 developmental process
1.36 2.73e-05 GO:0007275 multicellular organismal development
2.40 2.76e-05 GO:0007268 synaptic transmission
1.40 5.08e-05 GO:0048731 system development
1.75 1.24e-04 GO:0051049 regulation of transport
1.70 1.64e-04 GO:0051128 regulation of cellular component organization
1.60 2.11e-04 GO:0010646 regulation of cell communication
1.55 3.55e-04 GO:0009966 regulation of signal transduction
1.34 4.61e-04 GO:0048856 anatomical structure development
1.97 6.06e-04 GO:0007267 cell-cell signaling
2.00 1.16e-03 GO:0051960 regulation of nervous system development
1.71 2.91e-03 GO:0007154 cell communication
1.32 3.47e-03 GO:0006810 transport
1.87 3.47e-03 GO:0055082 cellular chemical homeostasis
1.31 6.30e-03 GO:0051234 establishment of localization
1.85 6.40e-03 GO:0006873 cellular ion homeostasis
1.61 9.18e-03 GO:0048699 generation of neurons
1.97 1.24e-02 GO:0040012 regulation of locomotion
1.27 1.33e-02 GO:0051179 localization
1.78 1.40e-02 GO:0050801 ion homeostasis
1.58 1.43e-02 GO:0022008 neurogenesis
1.94 1.77e-02 GO:0031175 neuron projection development
1.92 2.06e-02 GO:0007420 brain development
2.43 2.49e-02 GO:0006813 potassium ion transport
1.34 2.52e-02 GO:0048869 cellular developmental process
1.83 2.60e-02 GO:0060284 regulation of cell development
2.63 2.66e-02 GO:0006887 exocytosis
1.72 3.74e-02 GO:0030001 metal ion transport
2.40 4.24e-02 GO:0010769 regulation of cell morphogenesis involved in differentiation
2.40 4.24e-02 GO:0022604 regulation of cell morphogenesis
2.28 4.43e-02 GO:0042391 regulation of membrane potential
2.02 4.94e-02 GO:0048812 neuron projection morphogenesis

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.49 2.56e-16 GO:0043005 neuron projection
2.57 2.75e-15 GO:0045202 synapse
1.87 9.65e-12 GO:0042995 cell projection
1.24 1.43e-11 GO:0005737 cytoplasm
1.41 2.19e-11 GO:0071944 cell periphery
2.81 2.67e-11 GO:0030425 dendrite
2.60 1.33e-10 GO:0044456 synapse part
2.83 1.95e-10 GO:0030424 axon
1.39 7.90e-10 GO:0005886 plasma membrane
3.51 3.15e-09 GO:0019717 synaptosome
2.30 6.04e-09 GO:0044463 cell projection part
3.42 2.53e-08 GO:0033267 axon part
2.37 5.96e-08 GO:0044297 cell body
2.41 6.17e-08 GO:0043025 neuronal cell body
1.47 4.82e-06 GO:0044459 plasma membrane part
1.59 9.33e-06 GO:0000267 cell fraction
1.67 2.67e-05 GO:0005624 membrane fraction
1.12 2.99e-05 GO:0005622 intracellular
1.80 3.32e-05 GO:0030054 cell junction
3.26 3.80e-05 GO:0008021 synaptic vesicle
1.12 4.74e-05 GO:0044424 intracellular part
1.64 4.81e-05 GO:0005626 insoluble fraction
2.65 8.39e-05 GO:0045211 postsynaptic membrane
1.21 1.03e-04 GO:0044444 cytoplasmic part
1.58 3.29e-04 GO:0005794 Golgi apparatus
8.21 1.68e-03 GO:0030673 axolemma
1.96 1.80e-03 GO:0031012 extracellular matrix
2.48 2.66e-03 GO:0030136 clathrin-coated vesicle
2.65 3.64e-03 GO:0044420 extracellular matrix part
1.58 4.22e-03 GO:0031982 vesicle
2.33 4.36e-03 GO:0030135 coated vesicle
4.58 4.70e-03 GO:0044304 main axon
1.58 6.29e-03 GO:0031410 cytoplasmic vesicle
1.70 6.49e-03 GO:0016023 cytoplasmic membrane-bounded vesicle
1.95 7.12e-03 GO:0005578 proteinaceous extracellular matrix
2.92 7.23e-03 GO:0030427 site of polarized growth
2.98 8.93e-03 GO:0043679 axon terminus
1.66 1.08e-02 GO:0031988 membrane-bounded vesicle
2.87 1.54e-02 GO:0030426 growth cone
1.12 2.25e-02 GO:0016020 membrane
2.77 2.56e-02 GO:0044306 neuron projection terminus
2.83 4.86e-02 GO:0043197 dendritic spine

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.29 9.51e-10 GO:0005515 protein binding
1.13 1.26e-05 GO:0005488 binding
2.76 4.66e-04 GO:0022843 voltage-gated cation channel activity
2.14 5.17e-04 GO:0022836 gated channel activity
2.11 2.82e-03 GO:0005261 cation channel activity
1.65 2.86e-03 GO:0015075 ion transmembrane transporter activity
1.73 4.10e-03 GO:0008092 cytoskeletal protein binding
1.87 4.57e-03 GO:0005216 ion channel activity
1.75 4.77e-03 GO:0008324 cation transmembrane transporter activity
2.29 5.30e-03 GO:0005244 voltage-gated ion channel activity
2.29 5.30e-03 GO:0022832 voltage-gated channel activity
2.05 7.43e-03 GO:0005083 small GTPase regulator activity
1.83 8.55e-03 GO:0022838 substrate-specific channel activity
1.55 1.24e-02 GO:0022891 substrate-specific transmembrane transporter activity
1.79 1.39e-02 GO:0030695 GTPase regulator activity
1.77 1.65e-02 GO:0060589 nucleoside-triphosphatase regulator activity
2.50 1.67e-02 GO:0005267 potassium channel activity
2.20 1.75e-02 GO:0005543 phospholipid binding
1.78 2.08e-02 GO:0015267 channel activity
1.77 2.23e-02 GO:0022803 passive transmembrane transporter activity
1.52 2.83e-02 GO:0016301 kinase activity
2.73 3.32e-02 GO:0005249 voltage-gated potassium channel activity
1.47 4.25e-02 GO:0022892 substrate-specific transporter activity