Motif ID: GTF2A1,2.p2

Z-value: 1.335


Transcription factors associated with GTF2A1,2.p2:

Gene SymbolEntrez IDGene Name
Gtf2a1 83602 general transcription factor II A, 1
Gtf2a2 235459 general transcription factor II A, 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gtf2a2chr9_+_698604490.374.0e-07Click!
Gtf2a1chr12_-_928280180.231.5e-03Click!


Activity profile for motif GTF2A1,2.p2.

activity profile for motif GTF2A1,2.p2


Sorted Z-values histogram for motif GTF2A1,2.p2

Sorted Z-values for motif GTF2A1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of GTF2A1,2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_71470766 21.839 Flna
filamin, alpha
chr7_-_26262552 18.439 NM_001039185
NM_001039186
NM_001039187
NM_011926
 Ceacam1



carcinoembryonic antigen-related cell adhesion molecule 1



chr11_+_94797565 17.527 NM_007742
 Col1a1
collagen, type I, alpha 1
chr1_+_90062617 16.682 Ugt1a5
UDP glucuronosyltransferase 1 family, polypeptide A5
chr11_-_83391984 16.074 Ccl9
chemokine (C-C motif) ligand 9
chr19_+_9091248 14.911 Ahnak
AHNAK nucleoprotein (desmoyokin)
chr11_-_83392109 14.535 Ccl9
chemokine (C-C motif) ligand 9
chr1_+_132723258 13.630 NM_011082
 Pigr
polymeric immunoglobulin receptor
chr1_+_132723277 13.215 Pigr
polymeric immunoglobulin receptor
chr3_+_92019756 13.022 NM_001164787
NM_011468
 Sprr2a2
Sprr2a1
small proline-rich protein 2A2
small proline-rich protein 2A1
chr3_+_88128944 12.553 NM_020003
 0610031J06Rik
RIKEN cDNA 0610031J06 gene
chr3_-_88307198 12.398 Lmna
lamin A
chr2_+_117937623 11.910 NM_011580
 Thbs1
thrombospondin 1
chr6_-_82724366 11.767 NM_013820
 Hk2
hexokinase 2
chr3_-_88307253 11.505 NM_001002011
NM_001111102
 Lmna

lamin A

chr11_+_75469516 11.383 NM_001080775
 Myo1c
myosin IC
chr1_-_134036041 11.231 NM_008795
 Cdk18
cyclin-dependent kinase 18
chr2_+_35159780 10.881 Gsn
gelsolin
chr11_-_3429909 10.723 Smtn
smoothelin
chr7_-_52715059 10.720 NM_010240
 Gm15590
Ftl1
Ftl2
ferritin light chain 1 pseudogene
ferritin light chain 1
ferritin light chain 2

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 48 entries
Enrichment   P-value GO Accession GO Term
2.27 3.69e-03 GO:0001568 blood vessel development
2.10 3.98e-02 GO:0001701 in utero embryonic development
2.09 1.18e-04 GO:0009792 embryo development ending in birth or egg hatching
2.09 1.66e-04 GO:0043009 chordate embryonic development
2.08 2.94e-02 GO:0001944 vasculature development
2.04 4.40e-03 GO:0048870 cell motility
2.04 4.40e-03 GO:0051674 localization of cell
2.04 1.32e-02 GO:0016477 cell migration
1.99 1.17e-03 GO:0072358 cardiovascular system development
1.99 1.17e-03 GO:0072359 circulatory system development
1.95 1.39e-02 GO:0006928 cellular component movement
1.91 1.23e-03 GO:0040011 locomotion
1.86 1.78e-02 GO:0048646 anatomical structure formation involved in morphogenesis
1.76 4.20e-04 GO:0009888 tissue development
1.76 2.08e-02 GO:0012501 programmed cell death
1.75 1.75e-03 GO:0009790 embryo development
1.74 4.41e-02 GO:0006915 apoptosis
1.72 7.65e-03 GO:0045595 regulation of cell differentiation
1.71 3.73e-03 GO:0048468 cell development
1.70 3.93e-03 GO:2000026 regulation of multicellular organismal development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 33 entries
Enrichment   P-value GO Accession GO Term
7.80 1.91e-02 GO:0005583 fibrillar collagen
5.85 4.06e-03 GO:0005581 collagen
3.47 7.45e-03 GO:0001726 ruffle
3.34 6.71e-03 GO:0005604 basement membrane
3.32 1.16e-04 GO:0044420 extracellular matrix part
2.53 4.52e-03 GO:0031252 cell leading edge
2.30 7.76e-05 GO:0031012 extracellular matrix
2.26 8.03e-04 GO:0005578 proteinaceous extracellular matrix
2.22 1.79e-02 GO:0016323 basolateral plasma membrane
1.66 4.21e-04 GO:0044421 extracellular region part
1.59 5.57e-03 GO:0044430 cytoskeletal part
1.54 2.30e-04 GO:0005829 cytosol
1.52 5.73e-04 GO:0005856 cytoskeleton
1.49 6.59e-07 GO:0043228 non-membrane-bounded organelle
1.49 6.59e-07 GO:0043232 intracellular non-membrane-bounded organelle
1.48 3.78e-02 GO:0042995 cell projection
1.41 5.39e-03 GO:0005576 extracellular region
1.38 1.92e-08 GO:0044422 organelle part
1.38 4.63e-08 GO:0044446 intracellular organelle part
1.36 3.86e-11 GO:0044444 cytoplasmic part

Gene overrepresentation in function category:

Showing 1 to 11 of 11 entries
Enrichment   P-value GO Accession GO Term
12.68 9.52e-07 GO:0048407 platelet-derived growth factor binding
5.83 2.12e-03 GO:0005201 extracellular matrix structural constituent
3.76 8.56e-03 GO:0005178 integrin binding
3.22 1.76e-03 GO:0019838 growth factor binding
2.20 1.89e-03 GO:0003779 actin binding
1.83 6.09e-03 GO:0008092 cytoskeletal protein binding
1.68 3.46e-03 GO:0042802 identical protein binding
1.37 8.47e-12 GO:0005515 protein binding
1.34 3.73e-02 GO:0000166 nucleotide binding
1.25 8.48e-18 GO:0005488 binding
1.20 1.88e-02 GO:0003824 catalytic activity