Motif ID: GUAACAG

Z-value: 0.840


Mature miRNA associated with seed GUAACAG:

NamemiRBase Accession
mmu-miR-194 MIMAT0000224



Activity profile for motif GUAACAG.

activity profile for motif GUAACAG


Sorted Z-values histogram for motif GUAACAG

Sorted Z-values for motif GUAACAG



Network of associatons between targets according to the STRING database.



First level regulatory network of GUAACAG

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_+_3806955 11.633 NM_007872
Dnmt3a
DNA methyltransferase 3A
chr17_-_51971946 11.048 NM_009122
Satb1
special AT-rich sequence binding protein 1
chr17_-_51951378 10.683 NM_001163630
Satb1
special AT-rich sequence binding protein 1
chr5_-_25004598 9.885 NM_001081383
Mll3
myeloid/lymphoid or mixed-lineage leukemia 3
chr2_+_92024338 9.814 NM_138755
Phf21a
PHD finger protein 21A
chr17_+_15841889 8.887 NM_007690
Chd1
chromodomain helicase DNA binding protein 1
chr8_+_81033220 8.590 NM_029736
Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr17_-_51972514 8.377 NM_001163632
Satb1
special AT-rich sequence binding protein 1
chr2_-_179711350 8.362 NM_001081092
Taf4a
TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr5_-_64360058 7.775 NM_145923
Rell1
RELT-like 1
chr18_+_64500017 7.749 NM_194268
Onecut2
one cut domain, family member 2
chr7_+_119822831 7.700 NM_001166584
NM_009346
Tead1

TEA domain family member 1

chr1_-_140071818 7.265 NM_001111316
NM_011210
Ptprc

protein tyrosine phosphatase, receptor type, C

chr2_+_4802609 7.226 NM_175400
Sephs1
selenophosphate synthetase 1
chr17_-_79420125 7.086 NM_001171004
NM_029239
Prkd3

protein kinase D3

chr17_-_51965912 6.619 NM_001163631
Satb1
special AT-rich sequence binding protein 1
chr12_-_85559793 6.535 NM_001163501
C130039O16Rik
RIKEN cDNA C130039O16 gene
chr3_+_52072251 6.457 NM_019739
Foxo1
forkhead box O1
chr11_-_100711785 6.454 NM_001113563
Stat5b
signal transducer and activator of transcription 5B
chr12_-_58647074 6.429 NM_008259
Foxa1
forkhead box A1
chr8_-_27229485 6.384 NM_207659
Hook3
hook homolog 3 (Drosophila)
chr15_+_37162790 6.340 NM_026496
Grhl2
grainyhead-like 2 (Drosophila)
chr1_+_92949986 6.198 NM_001111311
NM_008515
Lrrfip1

leucine rich repeat (in FLII) interacting protein 1

chr12_+_72116953 6.113 NM_001081195
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr17_-_79407844 5.872 NM_001171005
Prkd3
protein kinase D3
chr18_+_83080270 5.576 NM_183033
Zfp516
zinc finger protein 516
chr13_+_109106530 5.576 NM_178683
Depdc1b
DEP domain containing 1B
chr15_+_96117952 5.521 NM_175251
Arid2
AT rich interactive domain 2 (ARID, RFX-like)
chr10_+_39451923 5.486 NM_011264
Rev3l
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chr1_+_168931547 5.437 NM_001160261
NM_001160262
NM_175461
Fam78b


family with sequence similarity 78, member B


chr7_+_119902897 5.410 NM_001166585
Tead1
TEA domain family member 1
chr2_+_49307005 5.130 NM_172663
Epc2
enhancer of polycomb homolog 2 (Drosophila)
chr8_-_36558514 5.062 NM_026067
Eri1
exoribonuclease 1
chr4_+_134676559 5.028 NM_019732
Runx3
runt related transcription factor 3
chr15_-_50721552 4.869 NM_032000
Trps1
trichorhinophalangeal syndrome I (human)
chr7_-_107007359 4.838 NM_025668
Spcs2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr16_+_44139908 4.789 NM_028108
Naa50
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr5_-_145726643 4.759 NM_001038627
NM_029438
Smurf1

SMAD specific E3 ubiquitin protein ligase 1

chr18_+_83084023 4.592 NM_001177464
Zfp516
zinc finger protein 516
chr3_+_88336316 4.514 NM_001029890
Mex3a
mex3 homolog A (C. elegans)
chr3_+_58219610 4.490 NM_001081229
Tsc22d2
TSC22 domain family, member 2
chr2_+_92025639 4.404 NM_001109691
Phf21a
PHD finger protein 21A
chr17_-_71202829 4.321 NM_001164074
Tgif1
TGFB-induced factor homeobox 1
chr2_+_112106470 4.292 NM_133649
Slc12a6
solute carrier family 12, member 6
chr12_-_85534964 4.273 NM_001163502
C130039O16Rik
RIKEN cDNA C130039O16 gene
chr7_-_141416778 4.259 NM_007400
Adam12
a disintegrin and metallopeptidase domain 12 (meltrin alpha)
chr1_-_45982242 4.252 NM_016917
Slc40a1
solute carrier family 40 (iron-regulated transporter), member 1
chr6_+_125045998 4.215 NM_145979
Chd4
chromodomain helicase DNA binding protein 4
chr1_+_193730645 4.092 NM_009579
Slc30a1
solute carrier family 30 (zinc transporter), member 1
chr7_+_75097142 4.036 NM_010513
Igf1r
insulin-like growth factor I receptor
chr7_-_123182257 3.982 NM_001025559
Sox6
SRY-box containing gene 6
chrX_+_82819294 3.924 NM_025729
Tab3
TGF-beta activated kinase 1/MAP3K7 binding protein 3
chr6_-_39156706 3.833 NM_001033430
Jhdm1d
jumonji C domain-containing histone demethylase 1 homolog D (S. cerevisiae)
chr7_+_28390872 3.790 NM_007434
Akt2
thymoma viral proto-oncogene 2
chr17_-_71200462 3.752 NM_009372
Tgif1
TGFB-induced factor homeobox 1
chr9_-_71440061 3.706 NM_001033208
Gcom1
GRINL1A complex locus
chr8_+_109817355 3.706 NM_018823
NM_133957
Nfat5

nuclear factor of activated T-cells 5

chr17_-_71201055 3.686 NM_001164075
Tgif1
TGFB-induced factor homeobox 1
chr19_+_21346734 3.661 NM_009551
Zfand5
zinc finger, AN1-type domain 5
chr19_+_57435498 3.658 NM_145505
Fam160b1
family with sequence similarity 160, member B1
chr19_+_55816299 3.655 NM_001142918
NM_001142919
NM_001142920
NM_001142921
NM_001142922
NM_001142923
NM_009333
Tcf7l2






transcription factor 7-like 2, T-cell specific, HMG-box






chr4_-_126145660 3.637 NM_153403
Eif2c1
eukaryotic translation initiation factor 2C, 1
chr7_+_134628622 3.600 NM_010183
Fbrs
fibrosin
chr17_-_71196116 3.584 NM_001164077
Tgif1
TGFB-induced factor homeobox 1
chr19_+_55969810 3.580 NM_001142924
Tcf7l2
transcription factor 7-like 2, T-cell specific, HMG-box
chr1_+_133807034 3.569 NM_001145804
NM_175294
Nucks1

nuclear casein kinase and cyclin-dependent kinase substrate 1

chr6_+_38383918 3.555 NM_177185
Ubn2
ubinuclein 2
chr10_+_66590005 3.510 NM_207221
Jmjd1c
jumonji domain containing 1C
chr10_+_7552260 3.509 NM_172785
Zc3h12d
zinc finger CCCH type containing 12D
chr1_+_52176281 3.484 NM_009283
Stat1
signal transducer and activator of transcription 1
chr8_-_82581887 3.453 NM_020259
Hhip
Hedgehog-interacting protein
chr17_-_71199129 3.433 NM_001164076
Tgif1
TGFB-induced factor homeobox 1
chr5_-_123438517 3.413 NM_001005866
Kdm2b
lysine (K)-specific demethylase 2B
chr2_+_112124767 3.337 NM_133648
Slc12a6
solute carrier family 12, member 6
chr16_-_32079317 3.323 NM_177326
Pak2
p21 protein (Cdc42/Rac)-activated kinase 2
chr5_-_108561512 3.298 NM_028876
Tmed5
transmembrane emp24 protein transport domain containing 5
chr5_-_123439064 3.249 NM_001003953
Kdm2b
lysine (K)-specific demethylase 2B
chr3_-_51129908 3.224 NM_023502
Elf2
E74-like factor 2
chr6_-_13627853 3.186 NM_175312
B630005N14Rik
RIKEN cDNA B630005N14 gene
chrX_-_71330931 3.124 NM_010788
NM_001081979
Mecp2

methyl CpG binding protein 2

chr6_-_72849854 3.049 NM_019715
Kcmf1
potassium channel modulatory factor 1
chr5_+_137960107 3.017 NM_031408
Gigyf1
GRB10 interacting GYF protein 1
chr12_+_72932064 3.006 NM_026102
NM_172464
Daam1

dishevelled associated activator of morphogenesis 1

chr6_+_120314116 2.939 NM_145997
Kdm5a
lysine (K)-specific demethylase 5A
chr19_+_47654508 2.929 NM_001164639
NM_009289
Slk

STE20-like kinase (yeast)

chr11_+_4167080 2.926 NM_001039537
Lif
leukemia inhibitory factor
chr11_+_4157570 2.915 NM_008501
Lif
leukemia inhibitory factor
chr6_+_8459595 2.874 NM_133236
Glcci1
glucocorticoid induced transcript 1
chr13_-_30077931 2.858 NM_010093
E2f3
E2F transcription factor 3
chr12_+_3891743 2.794 NM_153743
Dnmt3a
DNA methyltransferase 3A
chr5_-_123350242 2.761 NM_013910
Kdm2b
lysine (K)-specific demethylase 2B
chr7_-_118226515 2.710 NM_001040131
NM_013507
Eif4g2

eukaryotic translation initiation factor 4, gamma 2

chr13_+_55694491 2.654 NM_026211
Tmed9
transmembrane emp24 protein transport domain containing 9
chr1_-_84835871 2.650 NM_133975
Trip12
thyroid hormone receptor interactor 12
chr11_-_82684653 2.648 NM_001007465
NM_001164569
NM_001164571
Rffl


ring finger and FYVE like domain containing protein


chr15_+_38837839 2.576 NM_008056
Fzd6
frizzled homolog 6 (Drosophila)
chr3_+_61168428 2.550 NM_028712
Rap2b
RAP2B, member of RAS oncogene family
chr2_-_35960774 2.536 NM_001083125
NM_008500
Lhx6

LIM homeobox protein 6

chr1_+_191552133 2.526 NM_008976
Ptpn14
protein tyrosine phosphatase, non-receptor type 14
chr11_-_115397455 2.505 NM_133354
Sumo2
SMT3 suppressor of mif two 3 homolog 2 (yeast)
chr1_+_140860285 2.493 NM_001166501
Dennd1b
DENN/MADD domain containing 1B
chr11_-_120852609 2.488 NM_027874
NM_139059
Csnk1d

casein kinase 1, delta

chr12_+_4924157 2.459 NM_001099628
Atad2b
ATPase family, AAA domain containing 2B
chr19_+_53674862 2.382 NM_007790
Smc3
structural maintenace of chromosomes 3
chr6_+_83276009 2.333 NM_145571
Mobkl1b
MOB1, Mps One Binder kinase activator-like 1B (yeast)
chr10_-_94878845 2.333 NM_001168655
Socs2
suppressor of cytokine signaling 2
chr2_+_29917543 2.308 NM_023871
Set
SET nuclear oncogene
chr12_-_21379292 2.292 NM_009615
Adam17
a disintegrin and metallopeptidase domain 17
chr5_-_92739036 2.228 NM_172713
Sdad1
SDA1 domain containing 1
chr3_-_116126932 2.221 NM_001080818
NM_001173553
Cdc14a

CDC14 cell division cycle 14 homolog A (S. cerevisiae)

chrX_-_50723622 2.213 NM_027409
Mospd1
motile sperm domain containing 1
chr4_-_107704544 2.207 NM_172874
Podn
podocan
chr10_-_117283020 2.192 NM_024457
Rap1b
RAS related protein 1b
chr13_+_55311142 2.183 NM_008739
Nsd1
nuclear receptor-binding SET-domain protein 1
chr9_+_70390659 2.168 NM_025690
Sltm
SAFB-like, transcription modulator
chr7_-_107128967 2.061 NM_175388
Rnf169
ring finger protein 169
chr1_-_64784316 2.043 NM_001042659
NM_022721
Fzd5

frizzled homolog 5 (Drosophila)

chr2_+_92061718 2.043 NM_001109690
Phf21a
PHD finger protein 21A
chr9_+_72655019 2.037 NM_175485
Prtg
protogenin homolog (Gallus gallus)
chr9_-_114753191 2.021 NM_027294
Cmtm8
CKLF-like MARVEL transmembrane domain containing 8
chr15_-_38008565 1.977 NM_001081359
NM_001112721
Ubr5

ubiquitin protein ligase E3 component n-recognin 5

chr5_+_124889925 1.958 NM_030241
Setd8
SET domain containing (lysine methyltransferase) 8
chr12_-_53072250 1.946 NM_177171
Heatr5a
HEAT repeat containing 5A
chr11_-_100683830 1.897 NM_011489
Stat5b
signal transducer and activator of transcription 5B
chrX_-_6765768 1.855 NM_016691
Clcn5
chloride channel 5
chr14_+_13116681 1.812 NM_146051
NM_178141
3830406C13Rik

RIKEN cDNA 3830406C13 gene

chr11_+_83664370 1.757 NM_009330
Hnf1b
HNF1 homeobox B
chr17_-_46419939 1.745 NM_028751
Tjap1
tight junction associated protein 1
chr18_-_36675458 1.736 NM_010415
Hbegf
heparin-binding EGF-like growth factor
chr9_+_118515769 1.702 NM_133721
Itga9
integrin alpha 9
chr1_+_140864297 1.677 NM_181347
Dennd1b
DENN/MADD domain containing 1B
chr7_+_28376578 1.668 NM_001110208
Akt2
thymoma viral proto-oncogene 2
chr11_-_77421308 1.660 NM_144825
Taok1
TAO kinase 1
chr4_-_41045132 1.644 NM_016689
Aqp3
aquaporin 3
chrX_+_70884742 1.635 NM_029352
Dusp9
dual specificity phosphatase 9
chr15_+_38837818 1.631 NM_001162494
Fzd6
frizzled homolog 6 (Drosophila)
chr11_-_82684245 1.621 NM_001164570
Rffl
ring finger and FYVE like domain containing protein
chr14_+_65977510 1.617 NM_199029
Zfp395
zinc finger protein 395
chr7_-_123174560 1.589 NM_001025560
Sox6
SRY-box containing gene 6
chr17_+_4995073 1.561 NM_001085355
Arid1b
AT rich interactive domain 1B (SWI-like)
chr15_+_80541675 1.555 NM_144812
Tnrc6b
trinucleotide repeat containing 6b
chr8_+_111238543 1.496 NM_007496
Zfhx3
zinc finger homeobox 3
chr2_-_35959513 1.494 NM_001083126
NM_001083127
Lhx6

LIM homeobox protein 6

chr15_+_7760845 1.481 NM_010275
Gdnf
glial cell line derived neurotrophic factor
chr6_+_91423694 1.471 NM_028766
Tmem43
transmembrane protein 43
chr5_-_52581705 1.470 NM_001042620
NM_007839
Dhx15

DEAH (Asp-Glu-Ala-His) box polypeptide 15

chr19_-_23522811 1.468 NM_174857
Mamdc2
MAM domain containing 2
chr2_-_72817311 1.465 NM_001098425
Sp3
trans-acting transcription factor 3
chr10_+_127176590 1.441 NM_198035
Zbtb39
zinc finger and BTB domain containing 39
chr15_+_80629020 1.395 NM_177124
Tnrc6b
trinucleotide repeat containing 6b
chr5_+_124990703 1.358 NM_019770
Tmed2
transmembrane emp24 domain trafficking protein 2
chr7_-_54263783 1.356 NM_175318
Spty2d1
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr16_+_33185137 1.346 NM_176840
Osbpl11
oxysterol binding protein-like 11
chr9_-_70504934 1.329 NM_172772
Fam63b
family with sequence similarity 63, member B
chr5_-_20561610 1.299 NM_011203
Ptpn12
protein tyrosine phosphatase, non-receptor type 12
chr10_-_23069692 1.279 NM_010167
Eya4
eyes absent 4 homolog (Drosophila)
chr6_+_146837012 1.271 NM_001170433
NM_026221
Ppfibp1

PTPRF interacting protein, binding protein 1 (liprin beta 1)

chr7_+_19679892 1.251 NM_011383
Six5
sine oculis-related homeobox 5 homolog (Drosophila)
chr14_-_70919994 1.223 NM_009755
Bmp1
bone morphogenetic protein 1
chr2_-_156005873 1.199 NM_133242
Rbm39
RNA binding motif protein 39
chr9_-_86465373 1.193 NM_001163746
NM_028352
Pgm3

phosphoglucomutase 3

chr11_+_87881747 1.175 NM_016686
Vezf1
vascular endothelial zinc finger 1
chr12_+_60230704 1.124 NM_001165254
NM_146034
Ctage5

CTAGE family, member 5

chr7_-_135034440 1.122 NM_001081268
Prss53
protease, serine, 53
chr11_+_59953583 1.099 NM_001037764
Rai1
retinoic acid induced 1
chr14_-_98568744 1.085 NM_001038610
NM_007826
Dach1

dachshund 1 (Drosophila)

chr10_-_94877824 1.042 NM_001168657
Socs2
suppressor of cytokine signaling 2
chr4_-_135129534 1.039 NM_001013756
Grhl3
grainyhead-like 3 (Drosophila)
chr11_-_82642528 1.032 NM_026097
Rffl
ring finger and FYVE like domain containing protein
chr10_-_94879435 1.025 NM_007706
Socs2
suppressor of cytokine signaling 2
chr12_+_60232417 1.023 NM_001165253
Ctage5
CTAGE family, member 5
chr2_-_180655611 1.007 NM_173761
Ythdf1
YTH domain family 1
chr18_+_35758269 0.991 NM_026420
Paip2
polyadenylate-binding protein-interacting protein 2
chr13_-_46060325 0.972 NM_009124
Atxn1
ataxin 1
chr1_+_185858324 0.960 NM_022019
Dusp10
dual specificity phosphatase 10
chr13_-_47025086 0.931 NM_010617
Kif13a
kinesin family member 13A
chr19_+_45005608 0.919 NM_001081225
Fam178a
family with sequence similarity 178, member A
chr7_-_123138599 0.915 NM_011445
Sox6
SRY-box containing gene 6
chr14_-_52857246 0.900 NM_201637
Chd8
chromodomain helicase DNA binding protein 8
chr1_-_16609325 0.892 NM_025773
Ube2w
ubiquitin-conjugating enzyme E2W (putative)
chr2_-_60560659 0.880 NM_001159564
Itgb6
integrin beta 6
chrX_-_45816308 0.877 NM_019680
Elf4
E74-like factor 4 (ets domain transcription factor)
chr2_-_160934743 0.863 NM_173368
Chd6
chromodomain helicase DNA binding protein 6
chr2_-_39046224 0.863 NM_178778
Scai
suppressor of cancer cell invasion
chr18_+_5591869 0.849 NM_011546
Zeb1
zinc finger E-box binding homeobox 1
chrX_-_138825032 0.824 NM_001033600
NM_019477
NM_207625
Acsl4


acyl-CoA synthetase long-chain family member 4


chr2_+_173902521 0.821 NM_001102423
NM_001102424
NM_001102425
NM_172675
Stx16



syntaxin 16



chr5_+_135625533 0.807 NM_013763
Tbl2
transducin (beta)-like 2
chr1_-_157820378 0.792 NM_001039184
Cep350
centrosomal protein 350
chr8_+_93352723 0.790 NM_177224
Chd9
chromodomain helicase DNA binding protein 9
chr8_-_8660610 0.774 NM_010111
Efnb2
ephrin B2
chr2_-_173102033 0.741 NM_022995
Pmepa1
prostate transmembrane protein, androgen induced 1
chr1_-_37592976 0.707 NM_173870
Mgat4a
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr11_-_100334076 0.705 NM_172565
Klhl11
kelch-like 11 (Drosophila)
chr13_+_97312572 0.683 NM_001164222
NM_023420
Col4a3bp

collagen, type IV, alpha 3 (Goodpasture antigen) binding protein

chr10_-_94878117 0.677 NM_001168656
Socs2
suppressor of cytokine signaling 2
chr2_-_72818502 0.672 NM_001018042
Sp3
trans-acting transcription factor 3
chr1_-_183950050 0.668 NM_001083120
NM_001083121
NM_008680
NM_010135
Enah



enabled homolog (Drosophila)



chr2_-_60511707 0.617 NM_021359
Itgb6
integrin beta 6
chr19_-_28085534 0.575 NM_011265
Rfx3
regulatory factor X, 3 (influences HLA class II expression)

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.76 3.44e-18 GO:0060255 regulation of macromolecule metabolic process
3.15 1.55e-17 GO:2000112 regulation of cellular macromolecule biosynthetic process
3.07 6.62e-17 GO:0010556 regulation of macromolecule biosynthetic process
2.64 1.44e-16 GO:0080090 regulation of primary metabolic process
2.62 2.31e-16 GO:0031323 regulation of cellular metabolic process
2.97 4.18e-16 GO:0010468 regulation of gene expression
2.45 1.09e-15 GO:0019222 regulation of metabolic process
2.90 1.68e-15 GO:0031326 regulation of cellular biosynthetic process
2.86 3.46e-15 GO:0009889 regulation of biosynthetic process
3.10 4.57e-15 GO:0006355 regulation of transcription, DNA-dependent
3.04 1.29e-14 GO:0051252 regulation of RNA metabolic process
3.44 7.07e-14 GO:0006351 transcription, DNA-dependent
2.80 7.64e-14 GO:0019219 regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
3.43 7.67e-14 GO:0032774 RNA biosynthetic process
2.77 1.34e-13 GO:0051171 regulation of nitrogen compound metabolic process
4.29 8.95e-12 GO:0006357 regulation of transcription from RNA polymerase II promoter
2.75 1.17e-10 GO:0016070 RNA metabolic process
2.58 1.31e-10 GO:0090304 nucleic acid metabolic process
2.66 5.13e-10 GO:0009059 macromolecule biosynthetic process
2.80 5.18e-10 GO:0048523 negative regulation of cellular process
2.69 5.49e-10 GO:0048519 negative regulation of biological process
2.04 6.06e-10 GO:0044260 cellular macromolecule metabolic process
2.63 1.24e-09 GO:0034645 cellular macromolecule biosynthetic process
2.34 1.26e-09 GO:0006139 nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.94 1.64e-09 GO:0043170 macromolecule metabolic process
2.51 6.20e-09 GO:0010467 gene expression
6.65 8.07e-09 GO:0016568 chromatin modification
5.27 1.26e-08 GO:0051276 chromosome organization
3.32 1.48e-08 GO:0010604 positive regulation of macromolecule metabolic process
2.15 4.83e-08 GO:0034641 cellular nitrogen compound metabolic process
2.12 5.82e-08 GO:0006807 nitrogen compound metabolic process
1.72 9.97e-08 GO:0044238 primary metabolic process
5.80 1.06e-07 GO:0006325 chromatin organization
3.06 1.76e-07 GO:0009893 positive regulation of metabolic process
4.14 4.09e-07 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
3.98 9.84e-07 GO:0010558 negative regulation of macromolecule biosynthetic process
3.31 1.25e-06 GO:0009892 negative regulation of metabolic process
3.01 1.46e-06 GO:0031325 positive regulation of cellular metabolic process
3.85 2.01e-06 GO:0031327 negative regulation of cellular biosynthetic process
1.54 2.69e-06 GO:0050789 regulation of biological process
3.37 2.85e-06 GO:0010605 negative regulation of macromolecule metabolic process
3.76 3.33e-06 GO:0009890 negative regulation of biosynthetic process
1.55 4.77e-06 GO:0050794 regulation of cellular process
1.51 4.93e-06 GO:0065007 biological regulation
3.91 6.31e-06 GO:0010629 negative regulation of gene expression
2.09 8.81e-06 GO:0044249 cellular biosynthetic process
3.27 1.02e-05 GO:0031324 negative regulation of cellular metabolic process
2.07 1.03e-05 GO:0009058 biosynthetic process
3.42 1.31e-05 GO:0045935 positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.64 1.38e-05 GO:0044237 cellular metabolic process
2.10 1.41e-05 GO:0007275 multicellular organismal development
3.59 1.76e-05 GO:0051254 positive regulation of RNA metabolic process
3.47 1.82e-05 GO:0010628 positive regulation of gene expression
3.34 2.24e-05 GO:0051173 positive regulation of nitrogen compound metabolic process
3.93 2.43e-05 GO:0051253 negative regulation of RNA metabolic process
4.69 2.82e-05 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
3.73 3.19e-05 GO:0045934 negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
2.50 3.76e-05 GO:0048513 organ development
3.67 4.24e-05 GO:0051172 negative regulation of nitrogen compound metabolic process
2.00 4.72e-05 GO:0032502 developmental process
3.40 5.11e-05 GO:0009790 embryo development
3.50 5.43e-05 GO:0045893 positive regulation of transcription, DNA-dependent
3.25 6.95e-05 GO:0010557 positive regulation of macromolecule biosynthetic process
3.14 8.19e-05 GO:0031328 positive regulation of cellular biosynthetic process
3.82 8.35e-05 GO:0045892 negative regulation of transcription, DNA-dependent
2.19 8.39e-05 GO:0048731 system development
3.08 1.23e-04 GO:0009891 positive regulation of biosynthetic process
1.50 2.95e-04 GO:0008152 metabolic process
2.55 4.34e-04 GO:0023051 regulation of signaling
2.01 4.46e-04 GO:0048518 positive regulation of biological process
2.16 4.71e-04 GO:0071841 cellular component organization or biogenesis at cellular level
3.70 5.55e-04 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
2.18 7.61e-04 GO:0071842 cellular component organization at cellular level
4.37 9.29e-04 GO:0009968 negative regulation of signal transduction
2.00 9.35e-04 GO:0048856 anatomical structure development
2.53 1.18e-03 GO:0009653 anatomical structure morphogenesis
2.02 1.68e-03 GO:0048522 positive regulation of cellular process
3.75 1.71e-03 GO:0009792 embryo development ending in birth or egg hatching
2.62 1.99e-03 GO:0009966 regulation of signal transduction
2.71 2.45e-03 GO:0010646 regulation of cell communication
2.91 2.85e-03 GO:0009888 tissue development
4.01 2.91e-03 GO:0023057 negative regulation of signaling
4.00 3.00e-03 GO:0010648 negative regulation of cell communication
2.41 3.32e-03 GO:0006996 organelle organization
2.56 4.76e-03 GO:0007399 nervous system development
3.60 5.94e-03 GO:0048585 negative regulation of response to stimulus
3.48 9.14e-03 GO:0072358 cardiovascular system development
3.48 9.14e-03 GO:0072359 circulatory system development
3.86 9.36e-03 GO:0060429 epithelium development
2.86 9.70e-03 GO:0022008 neurogenesis
60.61 9.91e-03 GO:0003339 regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
3.43 1.10e-02 GO:0048646 anatomical structure formation involved in morphogenesis
2.92 1.19e-02 GO:0048699 generation of neurons
4.92 1.68e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
1.81 1.76e-02 GO:0071840 cellular component organization or biogenesis
2.15 2.34e-02 GO:0006464 protein modification process
3.39 2.38e-02 GO:0043009 chordate embryonic development
14.43 2.41e-02 GO:0030856 regulation of epithelial cell differentiation
1.81 2.52e-02 GO:0016043 cellular component organization
2.11 2.56e-02 GO:0043412 macromolecule modification
2.69 2.58e-02 GO:2000026 regulation of multicellular organismal development
2.15 3.26e-02 GO:0048583 regulation of response to stimulus
9.78 3.52e-02 GO:0016458 gene silencing
3.78 4.70e-02 GO:0007167 enzyme linked receptor protein signaling pathway
1.97 4.76e-02 GO:0048869 cellular developmental process

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.90 4.01e-09 GO:0005634 nucleus
1.42 3.18e-08 GO:0005622 intracellular
1.43 3.34e-08 GO:0044424 intracellular part
1.53 2.96e-07 GO:0043231 intracellular membrane-bounded organelle
1.53 3.41e-07 GO:0043227 membrane-bounded organelle
1.47 4.20e-07 GO:0043226 organelle
1.47 7.96e-07 GO:0043229 intracellular organelle
2.63 9.92e-06 GO:0031981 nuclear lumen
2.39 2.23e-05 GO:0044428 nuclear part
2.93 4.07e-05 GO:0005654 nucleoplasm
3.42 6.87e-05 GO:0044451 nucleoplasm part
2.35 1.11e-04 GO:0070013 intracellular organelle lumen
2.34 1.16e-04 GO:0043233 organelle lumen
2.30 1.89e-04 GO:0031974 membrane-enclosed lumen
4.31 1.48e-03 GO:0005667 transcription factor complex
1.57 1.83e-02 GO:0044446 intracellular organelle part
1.54 3.15e-02 GO:0044422 organelle part
1.15 3.65e-02 GO:0005623 cell
1.15 3.65e-02 GO:0044464 cell part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
2.54 2.54e-10 GO:0003676 nucleic acid binding
2.92 8.76e-10 GO:0003677 DNA binding
1.80 1.40e-08 GO:0005515 protein binding
1.43 3.06e-08 GO:0005488 binding
4.01 3.67e-08 GO:0001071 nucleic acid binding transcription factor activity
4.01 3.67e-08 GO:0003700 sequence-specific DNA binding transcription factor activity
5.81 4.63e-07 GO:0016564 transcription repressor activity
3.46 5.71e-07 GO:0030528 transcription regulator activity
3.83 3.65e-06 GO:0043565 sequence-specific DNA binding
4.60 2.17e-04 GO:0016563 transcription activator activity
4.98 7.23e-03 GO:0003682 chromatin binding
5.22 3.21e-02 GO:0004721 phosphoprotein phosphatase activity
2.10 4.28e-02 GO:0008270 zinc ion binding