Motif ID: GUAACAG

Z-value: 0.840


Mature miRNA associated with seed GUAACAG:

NamemiRBase Accession
mmu-miR-194 MIMAT0000224



Activity profile for motif GUAACAG.

activity profile for motif GUAACAG


Sorted Z-values histogram for motif GUAACAG

Sorted Z-values for motif GUAACAG



Network of associatons between targets according to the STRING database.



First level regulatory network of GUAACAG

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr12_+_3806955 11.633 NM_007872
 Dnmt3a
DNA methyltransferase 3A
chr17_-_51971946 11.048 NM_009122
 Satb1
special AT-rich sequence binding protein 1
chr17_-_51951378 10.683 NM_001163630
 Satb1
special AT-rich sequence binding protein 1
chr5_-_25004598 9.885 NM_001081383
 Mll3
myeloid/lymphoid or mixed-lineage leukemia 3
chr2_+_92024338 9.814 NM_138755
 Phf21a
PHD finger protein 21A
chr17_+_15841889 8.887 NM_007690
 Chd1
chromodomain helicase DNA binding protein 1
chr8_+_81033220 8.590 NM_029736
 Slc10a7
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr17_-_51972514 8.377 NM_001163632
 Satb1
special AT-rich sequence binding protein 1
chr2_-_179711350 8.362 NM_001081092
 Taf4a
TAF4A RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr5_-_64360058 7.775 NM_145923
 Rell1
RELT-like 1
chr18_+_64500017 7.749 NM_194268
 Onecut2
one cut domain, family member 2
chr7_+_119822831 7.700 NM_001166584
NM_009346
 Tead1

TEA domain family member 1

chr1_-_140071818 7.265 NM_001111316
NM_011210
 Ptprc

protein tyrosine phosphatase, receptor type, C

chr2_+_4802609 7.226 NM_175400
 Sephs1
selenophosphate synthetase 1
chr17_-_79420125 7.086 NM_001171004
NM_029239
 Prkd3

protein kinase D3

chr17_-_51965912 6.619 NM_001163631
 Satb1
special AT-rich sequence binding protein 1
chr12_-_85559793 6.535 NM_001163501
 C130039O16Rik
RIKEN cDNA C130039O16 gene
chr3_+_52072251 6.457 NM_019739
 Foxo1
forkhead box O1
chr11_-_100711785 6.454 NM_001113563
 Stat5b
signal transducer and activator of transcription 5B
chr12_-_58647074 6.429 NM_008259
 Foxa1
forkhead box A1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 105 entries
Enrichment   P-value GO Accession GO Term
60.61 9.91e-03 GO:0003339 regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis
14.43 2.41e-02 GO:0030856 regulation of epithelial cell differentiation
9.78 3.52e-02 GO:0016458 gene silencing
6.65 8.07e-09 GO:0016568 chromatin modification
5.80 1.06e-07 GO:0006325 chromatin organization
5.27 1.26e-08 GO:0051276 chromosome organization
4.92 1.68e-02 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway
4.69 2.82e-05 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
4.37 9.29e-04 GO:0009968 negative regulation of signal transduction
4.29 8.95e-12 GO:0006357 regulation of transcription from RNA polymerase II promoter
4.14 4.09e-07 GO:2000113 negative regulation of cellular macromolecule biosynthetic process
4.01 2.91e-03 GO:0023057 negative regulation of signaling
4.00 3.00e-03 GO:0010648 negative regulation of cell communication
3.98 9.84e-07 GO:0010558 negative regulation of macromolecule biosynthetic process
3.93 2.43e-05 GO:0051253 negative regulation of RNA metabolic process
3.91 6.31e-06 GO:0010629 negative regulation of gene expression
3.86 9.36e-03 GO:0060429 epithelium development
3.85 2.01e-06 GO:0031327 negative regulation of cellular biosynthetic process
3.82 8.35e-05 GO:0045892 negative regulation of transcription, DNA-dependent
3.78 4.70e-02 GO:0007167 enzyme linked receptor protein signaling pathway

Gene overrepresentation in compartment category:

Showing 1 to 19 of 19 entries
Enrichment   P-value GO Accession GO Term
4.31 1.48e-03 GO:0005667 transcription factor complex
3.42 6.87e-05 GO:0044451 nucleoplasm part
2.93 4.07e-05 GO:0005654 nucleoplasm
2.63 9.92e-06 GO:0031981 nuclear lumen
2.39 2.23e-05 GO:0044428 nuclear part
2.35 1.11e-04 GO:0070013 intracellular organelle lumen
2.34 1.16e-04 GO:0043233 organelle lumen
2.30 1.89e-04 GO:0031974 membrane-enclosed lumen
1.90 4.01e-09 GO:0005634 nucleus
1.57 1.83e-02 GO:0044446 intracellular organelle part
1.54 3.15e-02 GO:0044422 organelle part
1.53 2.96e-07 GO:0043231 intracellular membrane-bounded organelle
1.53 3.41e-07 GO:0043227 membrane-bounded organelle
1.47 4.20e-07 GO:0043226 organelle
1.47 7.96e-07 GO:0043229 intracellular organelle
1.43 3.34e-08 GO:0044424 intracellular part
1.42 3.18e-08 GO:0005622 intracellular
1.15 3.65e-02 GO:0005623 cell
1.15 3.65e-02 GO:0044464 cell part

Gene overrepresentation in function category:

Showing 1 to 13 of 13 entries
Enrichment   P-value GO Accession GO Term
5.81 4.63e-07 GO:0016564 transcription repressor activity
5.22 3.21e-02 GO:0004721 phosphoprotein phosphatase activity
4.98 7.23e-03 GO:0003682 chromatin binding
4.60 2.17e-04 GO:0016563 transcription activator activity
4.01 3.67e-08 GO:0001071 nucleic acid binding transcription factor activity
4.01 3.67e-08 GO:0003700 sequence-specific DNA binding transcription factor activity
3.83 3.65e-06 GO:0043565 sequence-specific DNA binding
3.46 5.71e-07 GO:0030528 transcription regulator activity
2.92 8.76e-10 GO:0003677 DNA binding
2.54 2.54e-10 GO:0003676 nucleic acid binding
2.10 4.28e-02 GO:0008270 zinc ion binding
1.80 1.40e-08 GO:0005515 protein binding
1.43 3.06e-08 GO:0005488 binding