Motif ID: GUAGUGU

Z-value: 1.625


Mature miRNA associated with seed GUAGUGU:

NamemiRBase Accession
mmu-miR-142-3p MIMAT0000155



Activity profile for motif GUAGUGU.

activity profile for motif GUAGUGU


Sorted Z-values histogram for motif GUAGUGU

Sorted Z-values for motif GUAGUGU



Network of associatons between targets according to the STRING database.



First level regulatory network of GUAGUGU

PNG image of the network

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Top targets:


Showing 1 to 20 of 196 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_-_66489416 35.585 NM_139065
 Rbm47
RNA binding motif protein 47
chr2_-_169956719 32.621 NM_001033299
 Zfp217
zinc finger protein 217
chr8_+_74659107 32.344 NM_001001491
 Tpm4
tropomyosin 4
chr5_-_66543123 32.090 NM_001127382
 Rbm47
RNA binding motif protein 47
chr5_-_66542161 29.477 NM_178446
 Rbm47
RNA binding motif protein 47
chr15_-_99705812 27.293 NM_001113545
 Lima1
LIM domain and actin binding 1
chr10_-_36858671 26.848 NM_008538
 Marcks
myristoylated alanine rich protein kinase C substrate
chr15_-_99650502 26.790 NM_023063
 Lima1
LIM domain and actin binding 1
chr17_-_31992708 26.388 NM_010831
 Sik1
salt inducible kinase 1
chr7_+_52273317 26.080 NM_009101
 Rras
Harvey rat sarcoma oncogene, subgroup R
chr12_-_56087322 24.019 NM_013815
 Baz1a
bromodomain adjacent to zinc finger domain 1A
chr2_-_169968174 23.910 NM_001159683
 Zfp217
zinc finger protein 217
chr2_-_103143352 20.867 NM_007914
 Ehf
ets homologous factor
chr15_+_10106992 20.234 NM_011169
 Prlr
prolactin receptor
chr5_+_65361309 19.088 NM_026667
 Fam114a1
family with sequence similarity 114, member A1
chr11_+_115685365 18.401 NM_145438
 Llgl2
lethal giant larvae homolog 2 (Drosophila)
chr9_-_35007875 18.327 NM_001177845
 Tirap
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
chr9_-_35007458 16.785 NM_001177847
NM_001177846
NM_054096
 Tirap


toll-interleukin 1 receptor (TIR) domain-containing adaptor protein


chr13_-_114408704 16.770 NM_130796
 Snx18
sorting nexin 18
chr18_+_66618186 16.281 NM_021451
 Pmaip1
phorbol-12-myristate-13-acetate-induced protein 1

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 106 entries
Enrichment   P-value GO Accession GO Term
15.94 1.36e-02 GO:0043507 positive regulation of JUN kinase activity
12.55 4.46e-02 GO:0043506 regulation of JUN kinase activity
8.70 1.53e-02 GO:0070302 regulation of stress-activated protein kinase signaling cascade
8.10 2.43e-02 GO:0019221 cytokine-mediated signaling pathway
5.65 1.12e-02 GO:0043408 regulation of MAPKKK cascade
4.96 1.40e-02 GO:0033674 positive regulation of kinase activity
4.78 1.98e-02 GO:0051347 positive regulation of transferase activity
4.44 3.32e-03 GO:0010627 regulation of intracellular protein kinase cascade
4.31 1.04e-02 GO:0009725 response to hormone stimulus
4.27 5.23e-03 GO:0043549 regulation of kinase activity
4.21 1.35e-02 GO:0045859 regulation of protein kinase activity
4.17 1.48e-03 GO:0071310 cellular response to organic substance
4.16 1.46e-05 GO:0019220 regulation of phosphate metabolic process
4.16 1.46e-05 GO:0051174 regulation of phosphorus metabolic process
4.13 3.72e-05 GO:0042325 regulation of phosphorylation
4.09 8.52e-03 GO:0051338 regulation of transferase activity
4.07 3.99e-02 GO:0007167 enzyme linked receptor protein signaling pathway
4.03 1.01e-02 GO:0000122 negative regulation of transcription from RNA polymerase II promoter
3.87 9.33e-04 GO:0001932 regulation of protein phosphorylation
3.83 3.60e-02 GO:0009719 response to endogenous stimulus

Gene overrepresentation in compartment category:

Showing 1 to 20 of 22 entries
Enrichment   P-value GO Accession GO Term
78.63 3.18e-02 GO:0005900 oncostatin-M receptor complex
2.84 1.46e-03 GO:0005794 Golgi apparatus
2.45 2.92e-02 GO:0005654 nucleoplasm
2.31 5.60e-03 GO:0031981 nuclear lumen
2.28 3.67e-02 GO:0000267 cell fraction
2.15 1.01e-02 GO:0070013 intracellular organelle lumen
2.15 1.04e-02 GO:0043233 organelle lumen
2.10 1.50e-02 GO:0031974 membrane-enclosed lumen
1.84 9.82e-03 GO:0043234 protein complex
1.82 2.41e-06 GO:0005634 nucleus
1.74 1.11e-03 GO:0044446 intracellular organelle part
1.73 9.38e-04 GO:0044422 organelle part
1.58 2.74e-07 GO:0043231 intracellular membrane-bounded organelle
1.58 3.12e-07 GO:0043227 membrane-bounded organelle
1.57 1.43e-13 GO:0005622 intracellular
1.54 1.33e-11 GO:0044424 intracellular part
1.54 8.72e-08 GO:0043229 intracellular organelle
1.53 1.07e-07 GO:0043226 organelle
1.51 1.33e-02 GO:0044444 cytoplasmic part
1.47 1.88e-04 GO:0005737 cytoplasm

Gene overrepresentation in function category:

Showing 1 to 20 of 22 entries
Enrichment   P-value GO Accession GO Term
78.63 3.90e-02 GO:0004897 ciliary neurotrophic factor receptor activity
11.57 1.28e-02 GO:0004896 cytokine receptor activity
7.08 3.77e-02 GO:0019955 cytokine binding
5.17 1.80e-03 GO:0019901 protein kinase binding
4.33 9.30e-03 GO:0019900 kinase binding
4.10 1.59e-03 GO:0004674 protein serine/threonine kinase activity
3.57 2.67e-02 GO:0008289 lipid binding
3.44 3.22e-03 GO:0004672 protein kinase activity
3.06 7.89e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
2.99 1.76e-02 GO:0043565 sequence-specific DNA binding
2.90 5.74e-03 GO:0016301 kinase activity
2.74 2.93e-02 GO:0001071 nucleic acid binding transcription factor activity
2.74 2.93e-02 GO:0003700 sequence-specific DNA binding transcription factor activity
2.73 4.83e-02 GO:0046983 protein dimerization activity
2.69 9.85e-03 GO:0030528 transcription regulator activity
2.59 3.92e-02 GO:0019899 enzyme binding
2.48 4.31e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
2.25 8.40e-06 GO:0003676 nucleic acid binding
2.23 2.30e-03 GO:0003677 DNA binding
2.18 4.72e-02 GO:0008270 zinc ion binding