Motif ID: GUCAGUU

Z-value: 1.118


Mature miRNA associated with seed GUCAGUU:

NamemiRBase Accession
mmu-miR-223 MIMAT0000665



Activity profile for motif GUCAGUU.

activity profile for motif GUCAGUU


Sorted Z-values histogram for motif GUCAGUU

Sorted Z-values for motif GUCAGUU



Network of associatons between targets according to the STRING database.



First level regulatory network of GUCAGUU

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_90252228 17.553 NM_172563
Hlf
hepatic leukemia factor
chr2_+_103809709 12.589 NM_001142336
Lmo2
LIM domain only 2
chr2_+_103798150 11.472 NM_001142337
Lmo2
LIM domain only 2
chr7_+_129432585 11.303 NM_008855
Prkcb
protein kinase C, beta
chr7_+_107376116 11.017 NM_027629
Pgm2l1
phosphoglucomutase 2-like 1
chr2_+_103810274 10.305 NM_001142335
NM_008505
Lmo2

LIM domain only 2

chr19_+_37509290 9.656 NM_008245
Hhex
hematopoietically expressed homeobox
chr1_+_37356722 9.581 NM_030266
Inpp4a
inositol polyphosphate-4-phosphatase, type I
chr10_+_92623587 8.694 NM_146239
Cdk17
cyclin-dependent kinase 17
chr1_+_162836541 8.265 NM_001024952
Rc3h1
RING CCCH (C3H) domains 1
chr3_+_84619399 8.135 NM_001177773
Fbxw7
F-box and WD-40 domain protein 7
chr3_+_84668066 7.707 NM_001177774
Fbxw7
F-box and WD-40 domain protein 7
chr2_+_127161893 6.833 NM_010090
Dusp2
dual specificity phosphatase 2
chr9_-_66767436 6.699 NM_173413
Rab8b
RAB8B, member RAS oncogene family
chr3_-_119486305 6.646 NM_019550
Ptbp2
polypyrimidine tract binding protein 2
chr2_-_7002344 6.511 NM_001110229
NM_001110230
NM_001160292
Celf2


CUGBP, Elav-like family member 2


chr2_-_73224394 6.274 NM_001080707
NM_001190297
Gpr155

G protein-coupled receptor 155

chr4_-_86876328 6.142 NM_172426
Slc24a2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr10_+_89336253 6.067 NM_001128086
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr4_+_122860705 5.815 NM_174998
Hpcal4
hippocalcin-like 4
chr5_+_97426665 5.696 NM_080708
Bmp2k
BMP2 inducible kinase
chr2_-_66278870 5.522 NM_018733
Scn1a
sodium channel, voltage-gated, type I, alpha
chr2_-_7317824 5.264 NM_001110231
Celf2
CUGBP, Elav-like family member 2
chr2_-_7317513 5.220 NM_001110232
Celf2
CUGBP, Elav-like family member 2
chr2_+_65508501 5.181 NM_001099298
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr9_+_109834266 5.123 NM_008633
Mtap4
microtubule-associated protein 4
chr8_+_90818102 5.059 NM_001037724
Adcy7
adenylate cyclase 7
chr2_+_4480799 5.036 NM_001177844
Frmd4a
FERM domain containing 4A
chr8_+_90812964 4.944 NM_001037723
Adcy7
adenylate cyclase 7
chr2_+_136539143 4.872 NM_011428
Snap25
synaptosomal-associated protein 25
chr1_+_176431933 4.822 NM_019445
Fmn2
formin 2
chr4_+_124419115 4.801 NM_008385
Inpp5b
inositol polyphosphate-5-phosphatase B
chr15_-_98638348 4.770 NM_001013741
Ddn
dendrin
chr8_+_90806890 4.760 NM_001109756
Adcy7
adenylate cyclase 7
chr6_+_65621583 4.729 NM_172399
A930038C07Rik
RIKEN cDNA A930038C07 gene
chr5_+_151476361 4.707 NM_175310
Pds5b
PDS5, regulator of cohesion maintenance, homolog B (S. cerevisiae)
chr1_-_25886551 4.634 NM_175642
Bai3
brain-specific angiogenesis inhibitor 3
chrX_+_45499599 4.618 NM_028773
Sash3
SAM and SH3 domain containing 3
chr8_+_13907735 4.561 NM_025785
Fbxo25
F-box protein 25
chr2_-_6805937 4.433 NM_001110228
NM_001160293
NM_010160
Celf2


CUGBP, Elav-like family member 2


chr14_+_61253517 4.432 NM_001033272
Spata13
spermatogenesis associated 13
chr6_-_112897259 4.413 NM_080448
Srgap3
SLIT-ROBO Rho GTPase activating protein 3
chr6_-_57485419 4.391 NM_175523
Ppm1k
protein phosphatase 1K (PP2C domain containing)
chr2_+_6243767 4.390 NM_001080548
Usp6nl
USP6 N-terminal like
chr10_+_90039435 4.375 NM_001177396
NM_001177398
NM_181398
Ipw
Anks1b


imprinted gene in the Prader-Willi syndrome region
ankyrin repeat and sterile alpha motif domain containing 1B


chr10_+_90038471 4.335 NM_001177397
Anks1b
ankyrin repeat and sterile alpha motif domain containing 1B
chr17_+_78599556 4.316 NM_015800
Crim1
cysteine rich transmembrane BMP regulator 1 (chordin like)
chr6_+_53989925 4.301 NM_001163640
Chn2
chimerin (chimaerin) 2
chr10_+_52410306 4.286 NM_178675
Slc35f1
solute carrier family 35, member F1
chr8_+_90796301 4.283 NM_007406
Adcy7
adenylate cyclase 7
chr2_+_6273778 4.258 NM_181399
Usp6nl
USP6 N-terminal like
chr6_-_58857000 4.246 NM_021432
Nap1l5
nucleosome assembly protein 1-like 5
chr13_+_83643032 4.225 NM_001170537
NM_025282
Mef2c

myocyte enhancer factor 2C

chr2_-_65405546 4.222 NM_018732
Scn3a
sodium channel, voltage-gated, type III, alpha
chr11_-_4847968 4.167 NM_010904
Nefh
neurofilament, heavy polypeptide
chr11_-_88579517 4.164 NM_054043
Msi2
Musashi homolog 2 (Drosophila)
chr2_+_4073908 4.097 NM_172475
Frmd4a
FERM domain containing 4A
chr18_+_5591869 4.083 NM_011546
Zeb1
zinc finger E-box binding homeobox 1
chr2_-_104250490 4.078 NM_001033347
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr1_-_158869401 4.046 NM_001159966
Ralgps2
Ral GEF with PH domain and SH3 binding motif 2
chr9_+_64658817 4.010 NM_001162917
Dennd4a
DENN/MADD domain containing 4A
chr6_-_24905939 4.000 NM_177013
Tmem229a
transmembrane protein 229A
chr13_+_109444370 3.945 NM_011056
Pde4d
phosphodiesterase 4D, cAMP specific
chr15_+_66409094 3.942 NM_001081409
Phf20l1
PHD finger protein 20-like 1
chr12_+_56256090 3.892 NM_001100109
Srp54b
signal recognition particle 54B
chr11_+_59356187 3.847 NM_145827
Nlrp3
NLR family, pyrin domain containing 3
chr2_+_4322020 3.792 NM_001177843
Frmd4a
FERM domain containing 4A
chr2_-_72818502 3.755 NM_001018042
Sp3
trans-acting transcription factor 3
chr2_+_48805027 3.683 NM_029924
Mbd5
methyl-CpG binding domain protein 5
chr18_-_70212948 3.652 NM_030554
Rab27b
RAB27b, member RAS oncogene family
chr6_+_54222814 3.602 NM_023543
Chn2
chimerin (chimaerin) 2
chr4_-_86873866 3.579 NM_001110240
Slc24a2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr13_+_91600662 3.448 NM_024186
NM_024272
Ssbp2

single-stranded DNA binding protein 2

chr2_+_119722957 3.416 NM_001164274
NM_013720
Mga

MAX gene associated

chr2_-_13715101 3.364 NM_145838
St8sia6
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr12_+_90191833 3.304 NM_172544
Nrxn3
neurexin III
chr19_+_4154645 3.291 NM_016933
Ptprcap
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr18_-_70301202 3.275 NM_001082553
Rab27b
RAB27b, member RAS oncogene family
chr6_+_108163089 3.274 NM_010585
Itpr1
inositol 1,4,5-triphosphate receptor 1
chr7_-_88974235 3.232 NM_146193
Btbd1
BTB (POZ) domain containing 1
chr6_+_71657791 3.152 NM_178608
Reep1
receptor accessory protein 1
chr19_-_7180162 3.145 NM_201411
Flrt1
fibronectin leucine rich transmembrane protein 1
chr14_-_73725576 3.126 NM_009029
Rb1
retinoblastoma 1
chr15_-_86016336 3.092 NM_145475
Cerk
ceramide kinase
chrX_+_162676870 3.068 NM_001177961
NM_001177962
NM_023122
Gpm6b


glycoprotein m6b


chr17_+_48439264 3.053 NM_001033405
Treml2
triggering receptor expressed on myeloid cells-like 2
chr13_+_9093121 3.023 NM_172585
Larp4b
La ribonucleoprotein domain family, member 4B
chr7_+_128061257 3.023 NM_001164096
NM_025298
Polr3e

polymerase (RNA) III (DNA directed) polypeptide E

chr13_+_58907953 3.019 NM_008745
Ntrk2
neurotrophic tyrosine kinase, receptor, type 2
chr1_-_158869650 3.017 NM_001159965
NM_001159967
NM_001159968
NM_023884
Ralgps2



Ral GEF with PH domain and SH3 binding motif 2



chr10_+_20760625 2.993 NM_001177776
Ahi1
Abelson helper integration site 1
chrX_+_162782484 2.978 NM_001177955
NM_001177956
NM_001177957
NM_001177958
NM_001177959
NM_001177960
Gpm6b





glycoprotein m6b





chrX_+_133584130 2.968 NM_146261
Fam199x
family with sequence similarity 199, X-linked
chr1_-_162281701 2.957 NM_001038621
Rabgap1l
RAB GTPase activating protein 1-like
chr6_+_4853319 2.944 NM_181595
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr8_-_113917651 2.942 NM_178086
Fa2h
fatty acid 2-hydroxylase
chr1_+_78654399 2.903 NM_001001981
NM_001033606
NM_001136222
NM_028817
Utp14b
Acsl3


UTP14, U3 small nucleolar ribonucleoprotein, homolog B (yeast)
acyl-CoA synthetase long-chain family member 3


chr4_+_84530230 2.902 NM_175275
NM_177385
Cntln

centlein, centrosomal protein

chr1_+_138027943 2.892 NM_001039472
Kif21b
kinesin family member 21B
chr1_+_181476534 2.873 NM_146105
Cnst
consortin, connexin sorting protein
chr1_-_38721799 2.802 NM_010678
Aff3
AF4/FMR2 family, member 3
chr15_-_99358387 2.743 NM_001038658
NM_028224
Faim2

Fas apoptotic inhibitory molecule 2

chr11_+_4136787 2.741 NM_001013365
Osm
oncostatin M
chr13_-_94269616 2.695 NM_021310
Jmy
junction-mediating and regulatory protein
chr12_-_71448600 2.691 NM_001110202
NM_001110203
NM_053167
Trim9


tripartite motif-containing 9


chr14_+_120877548 2.686 NM_029519
Rap2a
RAS related protein 2a
chr5_+_22252006 2.667 NM_001081231
NM_029990
Lhfpl3

lipoma HMGIC fusion partner-like 3

chr16_-_78576898 2.630 NM_025967
D16Ertd472e
DNA segment, Chr 16, ERATO Doi 472, expressed
chr2_-_51790163 2.627 NM_001141982
Rbm43
RNA binding motif protein 43
chr16_+_17489743 2.607 NM_175178
Aifm3
apoptosis-inducing factor, mitochondrion-associated 3
chr2_-_51790406 2.544 NM_001141981
NM_030243
Rbm43

RNA binding motif protein 43

chr5_+_35104373 2.544 NM_010414
Htt
huntingtin
chr15_-_84388245 2.540 NM_177630
Ldoc1l
leucine zipper, down-regulated in cancer 1-like
chr1_-_74590801 2.536 NM_176972
Usp37
ubiquitin specific peptidase 37
chr3_-_36589048 2.534 NM_019510
Trpc3
transient receptor potential cation channel, subfamily C, member 3
chr2_+_49921978 2.525 NM_177139
Lypd6
LY6/PLAUR domain containing 6
chr8_+_90723069 2.506 NM_001164497
NM_001164498
NM_001164499
Papd5


PAP associated domain containing 5


chr9_-_54509658 2.496 NM_053178
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr4_+_138011061 2.478 NM_025451
Camk2n1
calcium/calmodulin-dependent protein kinase II inhibitor 1
chr16_+_13358513 2.454 NM_153588
Mkl2
MKL/myocardin-like 2
chr6_-_28781687 2.431 NM_138682
Lrrc4
leucine rich repeat containing 4
chr15_+_99532698 2.408 NM_031842
Smarcd1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 1
chr18_-_66129715 2.403 NM_145493
Cplx4
complexin 4
chr13_-_111070392 2.371 NM_023852
Rab3c
RAB3C, member RAS oncogene family
chr1_+_132613903 2.349 NM_178691
Yod1
YOD1 OTU deubiquitinating enzyme 1 homologue (S. cerevisiae)
chr1_-_171677653 2.306 NM_009062
Rgs4
regulator of G-protein signaling 4
chr8_-_63462080 2.296 NM_007711
NM_173873
NM_173874
Clcn3


chloride channel 3


chr5_-_100588826 2.289 NM_182841
Tmem150c
transmembrane protein 150C
chr2_-_136213509 2.287 NM_172858
Pak7
p21 protein (Cdc42/Rac)-activated kinase 7
chr2_+_28048592 2.285 NM_001038613
NM_001038614
Olfm1

olfactomedin 1

chr19_+_12873063 2.282 NM_134152
Lpxn
leupaxin
chr12_-_4038848 2.267 NM_001082483
Efr3b
EFR3 homolog B (S. cerevisiae)
chr7_+_107855215 2.256 NM_178764
Fam168a
family with sequence similarity 168, member A
chr5_-_87174825 2.248 NM_172880
Tmprss11e
transmembrane protease, serine 11e
chr1_+_148342795 2.240 NM_153539
Fam5c
family with sequence similarity 5, member C
chr6_+_134590957 2.204 NM_026371
Loh12cr1
loss of heterozygosity, 12, chromosomal region 1 homolog (human)
chr2_+_13995715 2.202 NM_011484
Stam
signal transducing adaptor molecule (SH3 domain and ITAM motif) 1
chr10_-_88720534 2.174 NM_178773
Ano4
anoctamin 4
chr5_+_123300153 2.173 NM_030564
Rnf34
ring finger protein 34
chr6_+_86354212 2.168 NM_001164078
NM_001164079
NM_011585
Tia1


cytotoxic granule-associated RNA binding protein 1


chr15_+_81767188 2.145 NM_145473
Csdc2
cold shock domain containing C2, RNA binding
chr19_-_19185685 2.145 NM_001043354
Rorb
RAR-related orphan receptor beta
chr10_+_20672352 2.142 NM_026203
Ahi1
Abelson helper integration site 1
chr2_-_72817311 2.141 NM_001098425
Sp3
trans-acting transcription factor 3
chr6_-_91465788 2.140 NM_009531
Xpc
xeroderma pigmentosum, complementation group C
chr13_+_41701584 2.127 NM_001163572
Tmem170b
transmembrane protein 170B
chr6_+_125095236 2.126 NM_178787
NM_001039669
Iffo1

intermediate filament family orphan 1

chrX_+_83115611 2.118 NM_001163539
5430427O19Rik
RIKEN cDNA 5430427O19 gene
chr5_-_25004598 2.115 NM_001081383
Mll3
myeloid/lymphoid or mixed-lineage leukemia 3
chr3_-_9833502 2.099 NM_001195031
NM_053182
Pag1

phosphoprotein associated with glycosphingolipid microdomains 1

chr8_-_63433528 2.097 NM_173876
Clcn3
chloride channel 3
chrX_+_103222548 2.096 NM_001109757
NM_009726
Atp7a

ATPase, Cu++ transporting, alpha polypeptide

chr5_+_30559138 2.089 NM_027652
Ept1
ethanolaminephosphotransferase 1 (CDP-ethanolamine-specific)
chr1_+_108068405 2.074 NM_133821
Phlpp1
PH domain and leucine rich repeat protein phosphatase 1
chr4_+_154338216 2.066 NM_172990
Pank4
pantothenate kinase 4
chr4_+_154624074 2.058 NM_001190445
2610002J02Rik
RIKEN cDNA 2610002J02 gene
chr8_+_23970006 2.038 NM_001081149
Myst3
MYST histone acetyltransferase (monocytic leukemia) 3
chr13_-_14615371 2.035 NM_001081348
Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr18_+_42435006 2.031 NM_172626
Rbm27
RNA binding motif protein 27
chr13_-_52626065 2.017 NM_001024474
Diras2
DIRAS family, GTP-binding RAS-like 2
chr5_-_100468240 2.015 NM_016690
Hnrpdl
heterogeneous nuclear ribonucleoprotein D-like
chr13_+_93195850 2.006 NM_175455
Ankrd34b
ankyrin repeat domain 34B
chr18_+_33098694 1.993 NM_009793
Camk4
calcium/calmodulin-dependent protein kinase IV
chr5_-_118694869 1.989 NM_172998
NM_001109902
Rnft2

ring finger protein, transmembrane 2

chr1_+_129670740 1.988 NM_028399
Ccnt2
cyclin T2
chr11_+_93857338 1.959 NM_027569
Spag9
sperm associated antigen 9
chr2_+_31428244 1.952 NM_001033389
Fubp3
far upstream element (FUSE) binding protein 3
chr2_+_158235580 1.944 NM_177658
Ralgapb
Ral GTPase activating protein, beta subunit (non-catalytic)
chr11_+_68902025 1.943 NM_009497
Vamp2
vesicle-associated membrane protein 2
chr15_+_6658368 1.940 NM_030168
Rictor
RPTOR independent companion of MTOR, complex 2
chr1_-_94998418 1.920 NM_001110315
NM_008440
Kif1a

kinesin family member 1A

chr7_-_88837850 1.918 NM_001164087
Homer2
homer homolog 2 (Drosophila)
chr17_+_47748530 1.910 NM_020048
Med20
mediator complex subunit 20
chr2_+_28061156 1.901 NM_001038612
NM_019498
Olfm1

olfactomedin 1

chr9_-_123883398 1.895 NM_009912
Ccr1
chemokine (C-C motif) receptor 1
chrX_+_97972559 1.892 NM_001177780
Dlg3
discs, large homolog 3 (Drosophila)
chr1_+_148344816 1.888 NM_001145807
Fam5c
family with sequence similarity 5, member C
chr7_+_63023547 1.887 NM_178706
Siglech
sialic acid binding Ig-like lectin H
chr9_+_104472090 1.878 NM_028719
Cpne4
copine IV
chr3_-_30868320 1.868 NM_001165954
NM_001165955
NM_001165956
NM_153421
Phc3



polyhomeotic-like 3 (Drosophila)



chr7_+_91040481 1.842 NM_023403
Mesdc2
mesoderm development candidate 2
chrX_+_97963061 1.841 NM_001177778
NM_016747
Dlg3

discs, large homolog 3 (Drosophila)

chr17_+_26852581 1.840 NM_029870
A930001N09Rik
RIKEN cDNA A930001N09 gene
chr10_+_122701051 1.837 NM_182807
Fam19a2
family with sequence similarity 19, member A2
chr15_+_81633102 1.833 NM_153484
Tef
thyrotroph embryonic factor
chr5_-_90312358 1.831 NM_001081401
NM_177872
Adamts3

a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 3

chr11_-_61668486 1.786 NM_013881
Ulk2
Unc-51 like kinase 2 (C. elegans)
chr12_+_89961317 1.782 NM_001198587
Nrxn3
neurexin III
chr6_-_77929660 1.778 NM_001109764
NM_009819
NM_145732
Ctnna2


catenin (cadherin associated protein), alpha 2


chr7_+_104480819 1.766 NM_001039039
Kctd21
potassium channel tetramerisation domain containing 21
chr12_+_112088488 1.760 NM_028365
Zfp839
zinc finger protein 839
chr9_+_66561492 1.760 NM_178396
Car12
carbonic anyhydrase 12
chr1_-_173164404 1.720 NM_010185
Fcer1g
Fc receptor, IgE, high affinity I, gamma polypeptide
chr16_+_45610535 1.718 NM_001159297
NM_008099
Gcet2

germinal center expressed transcript 2

chr2_-_180444687 1.718 NM_177852
Dido1
death inducer-obliterator 1
chr3_-_87734096 1.677 NM_153562
Rrnad1
ribosomal RNA adenine dimethylase domain containing 1
chr2_-_162486882 1.660 NM_021464
Ptprt
protein tyrosine phosphatase, receptor type, T
chr7_+_134439804 1.653 NM_008400
Itgal
integrin alpha L
chr1_+_179374783 1.651 NM_001012330
Zfp238
zinc finger protein 238
chr6_+_134589529 1.635 NM_001170479
Loh12cr1
loss of heterozygosity, 12, chromosomal region 1 homolog (human)

Gene Ontology Analysis

Nothing significant found in process category.

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
22.23 2.68e-04 GO:0001518 voltage-gated sodium channel complex
1.21 3.79e-04 GO:0005622 intracellular
17.10 1.29e-03 GO:0034706 sodium channel complex
1.19 5.85e-03 GO:0044424 intracellular part
1.11 1.41e-02 GO:0005623 cell
1.11 1.41e-02 GO:0044464 cell part
1.33 2.11e-02 GO:0005634 nucleus
26.67 2.27e-02 GO:0033268 node of Ranvier
1.19 3.93e-02 GO:0043229 intracellular organelle
2.24 4.57e-02 GO:0045202 synapse
1.19 4.81e-02 GO:0043226 organelle

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.24 2.07e-05 GO:0005488 binding
18.52 1.16e-03 GO:0005248 voltage-gated sodium channel activity
22.23 4.91e-03 GO:0031402 sodium ion binding
1.32 9.52e-03 GO:0005515 protein binding
2.67 3.17e-02 GO:0042578 phosphoric ester hydrolase activity