Motif ID: GUGCAAA

Z-value: 1.334


Mature miRNA associated with seed GUGCAAA:

NamemiRBase Accession
mmu-miR-19a MIMAT0000651
mmu-miR-19b MIMAT0000513



Activity profile for motif GUGCAAA.

activity profile for motif GUGCAAA


Sorted Z-values histogram for motif GUGCAAA

Sorted Z-values for motif GUGCAAA



Network of associatons between targets according to the STRING database.



First level regulatory network of GUGCAAA

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr6_-_92517359 23.719 NM_001134461
Prickle2
prickle homolog 2 (Drosophila)
chr6_-_92656148 22.675 NM_001081146
Prickle2
prickle homolog 2 (Drosophila)
chr6_-_92484838 22.629 NM_001134459
Prickle2
prickle homolog 2 (Drosophila)
chr6_-_92431385 21.504 NM_001134460
Prickle2
prickle homolog 2 (Drosophila)
chr12_-_73337707 19.938 NM_001007596
Rtn1
reticulon 1
chr12_-_73509925 19.747 NM_153457
Rtn1
reticulon 1
chr7_-_119302546 16.096 NM_015814
Dkk3
dickkopf homolog 3 (Xenopus laevis)
chr3_-_55987612 16.022 NM_030595
Nbea
neurobeachin
chrX_+_78315963 14.958 NM_138751
Tmem47
transmembrane protein 47
chr3_-_88576415 14.489 NM_018804
Syt11
synaptotagmin XI
chr3_-_148617598 14.443 NM_001081298
Lphn2
latrophilin 2
chr4_+_115894518 13.765 NM_181585
Pik3r3
phosphatidylinositol 3 kinase, regulatory subunit, polypeptide 3 (p55)
chr8_-_48437701 13.637 NM_175162
Stox2
storkhead box 2
chr10_+_24315247 13.495 NM_010217
Ctgf
connective tissue growth factor
chr6_+_54402876 13.366 NM_001167860
NM_001167861
Wipf3

WAS/WASL interacting protein family, member 3

chr8_-_48374755 13.210 NM_001114311
Stox2
storkhead box 2
chr12_-_8506790 12.952 NM_007483
Rhob
ras homolog gene family, member B
chr19_-_59150558 12.700 NM_001114312
NM_175172
4930506M07Rik

RIKEN cDNA 4930506M07 gene

chr17_+_44215761 12.598 NM_032003
NM_001168620
Enpp5

ectonucleotide pyrophosphatase/phosphodiesterase 5

chr9_-_117539030 12.402 NM_001172121
Rbms3
RNA binding motif, single stranded interacting protein
chr12_+_30622876 12.327 NM_181395
Pxdn
peroxidasin homolog (Drosophila)
chr1_+_12682510 12.300 NM_001198565
NM_001198566
Sulf1

sulfatase 1

chr1_-_113761344 12.214 NM_001081316
Dsel
dermatan sulfate epimerase-like
chr6_+_118016385 12.100 NM_027526
Rasgef1a
RasGEF domain family, member 1A
chr9_-_117161564 12.017 NM_001172122
NM_001172123
NM_001172124
NM_001172126
NM_178660
Rbms3




RNA binding motif, single stranded interacting protein




chr2_+_92439758 11.937 NM_023850
Chst1
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr9_-_107134182 11.901 NM_153413
Dock3
dedicator of cyto-kinesis 3
chr1_-_174136874 11.604 NM_011063
Pea15a
phosphoprotein enriched in astrocytes 15A
chr6_-_113841356 11.454 NM_001036684
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr15_-_37722161 11.307 NM_134094
Ncald
neurocalcin delta
chr10_+_59747208 11.268 NM_001146124
Psap
prosaposin
chr5_+_67137054 11.183 NM_001001980
Limch1
LIM and calponin homology domains 1
chr2_+_145068346 10.907 NM_053195
Slc24a3
solute carrier family 24 (sodium/potassium/calcium exchanger), member 3
chr4_-_25727109 10.763 NM_010243
Fut9
fucosyltransferase 9
chr15_-_37721754 10.696 NM_001170866
Ncald
neurocalcin delta
chr2_+_91490266 10.664 NM_001145902
Arhgap1
Rho GTPase activating protein 1
chr19_-_46401618 10.645 NM_028627
Psd
pleckstrin and Sec7 domain containing
chr6_-_113991945 10.477 NM_009723
Atp2b2
ATPase, Ca++ transporting, plasma membrane 2
chr1_+_12708582 10.473 NM_172294
Sulf1
sulfatase 1
chr10_+_59740373 10.312 NM_001146120
NM_001146121
NM_001146122
NM_001146123
NM_011179
Psap




prosaposin




chr15_-_44619541 10.127 NM_001032727
NM_176998
Sybu

syntabulin (syntaxin-interacting)

chr2_+_145611851 10.063 NM_028724
Rin2
Ras and Rab interactor 2
chr12_+_83412335 10.016 NM_172579
Sipa1l1
signal-induced proliferation-associated 1 like 1
chr12_+_41172639 9.776 NM_172803
Dock4
dedicator of cytokinesis 4
chrX_+_70918446 9.741 NM_001142809
NM_001142810
NM_133987
Slc6a8


solute carrier family 6 (neurotransmitter transporter, creatine), member 8


chr4_-_76240202 9.566 NM_011211
Ptprd
protein tyrosine phosphatase, receptor type, D
chr15_-_44584003 9.514 NM_178765
Sybu
syntabulin (syntaxin-interacting)
chr11_+_53380870 9.499 NM_008443
Kif3a
kinesin family member 3A
chr18_+_4634926 9.123 NM_001081963
9430020K01Rik
RIKEN cDNA 9430020K01 gene
chr3_-_115417932 9.068 NM_007901
S1pr1
sphingosine-1-phosphate receptor 1
chr10_+_56097078 9.021 NM_010288
Gja1
gap junction protein, alpha 1
chr15_-_37389073 8.927 NM_001170867
NM_001170868
Ncald

neurocalcin delta

chr18_-_23197156 8.833 NM_001161483
Nol4
nucleolar protein 4
chr3_+_121426422 8.823 NM_010171
F3
coagulation factor III
chr4_-_154735351 8.770 NM_008860
Prkcz
protein kinase C, zeta
chr10_+_21712008 8.725 NM_001161849
Sgk1
serum/glucocorticoid regulated kinase 1
chr9_-_54349409 8.696 NM_172771
Dmxl2
Dmx-like 2
chr18_+_37089837 8.582 NM_054072
Pcdha1
protocadherin alpha 1
chr2_-_151458256 8.559 NM_198214
Snph
syntaphilin
chr5_+_102194126 8.534 NM_173370
Cds1
CDP-diacylglycerol synthase 1
chr18_+_37120093 8.531 NM_009959
Pcdha5
protocadherin alpha 5
chr18_+_37179802 8.463 NM_138663
Pcdha12
protocadherin alpha 12
chr18_+_37098858 8.442 NM_198117
Pcdha2
protocadherin alpha 2
chr11_-_11927973 8.425 NM_001177629
Grb10
growth factor receptor bound protein 10
chr4_-_75779379 8.408 NM_001014288
Ptprd
protein tyrosine phosphatase, receptor type, D
chr10_+_21698470 8.345 NM_001161847
Sgk1
serum/glucocorticoid regulated kinase 1
chr14_+_12386043 8.316 NM_008981
Ptprg
protein tyrosine phosphatase, receptor type, G
chr10_-_108447674 8.313 NM_009306
Syt1
synaptotagmin I
chr18_+_37157533 8.298 NM_138661
Pcdha9
protocadherin alpha 9
chr2_+_106535757 8.155 NM_029837
Mpped2
metallophosphoesterase domain containing 2
chr3_-_32264572 8.127 NM_009517
Zmat3
zinc finger matrin type 3
chr18_+_37127284 7.990 NM_007767
Pcdha6
protocadherin alpha 6
chr11_-_61393108 7.908 NM_010148
Epn2
epsin 2
chr3_+_102538692 7.881 NM_027533
Tspan2
tetraspanin 2
chr18_+_37105758 7.860 NM_138662
Pcdha3
protocadherin alpha 3
chr10_+_21705909 7.774 NM_001161848
Sgk1
serum/glucocorticoid regulated kinase 1
chrX_+_100551808 7.745 NM_009767
Chic1
cysteine-rich hydrophobic domain 1
chr8_-_74195650 7.666 NM_001029873
Unc13a
unc-13 homolog A (C. elegans)
chr4_-_53172748 7.604 NM_013454
Abca1
ATP-binding cassette, sub-family A (ABC1), member 1
chr10_+_21714471 7.551 NM_011361
Sgk1
serum/glucocorticoid regulated kinase 1
chr18_+_37152024 7.463 NM_201243
Pcdha8
protocadherin alpha 8
chr18_+_37133455 7.453 NM_009957
Pcdha7
protocadherin alpha 7
chr7_-_31911884 7.386 NM_011322
Scn1b
sodium channel, voltage-gated, type I, beta
chr6_+_72047563 7.320 NM_001035228
NM_011375
St3gal5

ST3 beta-galactoside alpha-2,3-sialyltransferase 5

chr4_-_91038729 7.309 NM_010486
NM_207686
Elavl2

ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)

chr10_+_21601968 7.036 NM_001161845
Sgk1
serum/glucocorticoid regulated kinase 1
chr10_+_21713669 6.867 NM_001161850
Sgk1
serum/glucocorticoid regulated kinase 1
chr4_+_34011567 6.816 NM_007726
Cnr1
cannabinoid receptor 1 (brain)
chr10_+_52410306 6.801 NM_178675
Slc35f1
solute carrier family 35, member F1
chr2_+_106533615 6.789 NM_001143683
Mpped2
metallophosphoesterase domain containing 2
chr4_-_154719834 6.764 NM_001039079
Prkcz
protein kinase C, zeta
chr9_-_42913797 6.759 NM_027144
Arhgef12
Rho guanine nucleotide exchange factor (GEF) 12
chrX_+_109714134 6.732 NM_177747
Zfp711
zinc finger protein 711
chr12_+_83271002 6.623 NM_001167983
Sipa1l1
signal-induced proliferation-associated 1 like 1
chr4_-_91042997 6.617 NM_001177883
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr11_+_6963421 6.542 NM_009622
Adcy1
adenylate cyclase 1
chr12_-_112615921 6.451 NM_183016
Cdc42bpb
CDC42 binding protein kinase beta
chr17_+_72131286 6.396 NM_030179
Clip4
CAP-GLY domain containing linker protein family, member 4
chr11_+_78002249 6.382 NM_033475
Rab34
RAB34, member of RAS oncogene family
chr2_+_22923653 6.373 NM_001102436
NM_028793
Acbd5

acyl-Coenzyme A binding domain containing 5

chr13_+_113254277 6.343 NM_010560
Il6st
interleukin 6 signal transducer
chr4_-_109149038 6.341 NM_013876
Rnf11
ring finger protein 11
chr11_-_76322920 6.322 NM_198018
Abr
active BCR-related gene
chr11_+_78001871 6.271 NM_001159482
Rab34
RAB34, member of RAS oncogene family
chr5_+_18732863 6.257 NM_001170746
Magi2
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr15_-_101966611 6.242 NM_001033277
Spryd3
SPRY domain containing 3
chr12_+_39506844 6.191 NM_007960
Etv1
ets variant gene 1
chr16_+_58408609 6.157 NM_028523
Dcbld2
discoidin, CUB and LCCL domain containing 2
chr7_-_74904546 6.121 NM_183312
NM_201639
NM_207663
Synm


synemin, intermediate filament protein


chr18_-_67708826 6.069 NM_176832
Spire1
spire homolog 1 (Drosophila)
chr14_-_21299301 6.017 NM_001110794
NM_009674
Anxa7

annexin A7

chr18_+_37303622 5.983 NM_001003672
Pcdhac2
protocadherin alpha subfamily C, 2
chr11_-_76391228 5.905 NM_198894
Abr
active BCR-related gene
chr18_+_23912225 5.809 NM_001162941
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr17_-_66799086 5.798 NM_001114098
NM_172963
1110012J17Rik

RIKEN cDNA 1110012J17 gene

chr4_-_91066674 5.792 NM_207685
Elavl2
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr14_+_120674886 5.787 NM_175341
NM_207515
Mbnl2

muscleblind-like 2

chr13_-_13485585 5.765 NM_031999
Gpr137b
G protein-coupled receptor 137B
chr8_+_87560809 5.750 NM_145390
Tnpo2
transportin 2 (importin 3, karyopherin beta 2b)
chr7_+_127245860 5.711 NM_145586
Tmem159
transmembrane protein 159
chr13_+_94077988 5.669 NM_152134
Homer1
homer homolog 1 (Drosophila)
chr18_+_6765174 5.599 NM_181070
Rab18
RAB18, member RAS oncogene family
chr8_-_70342105 5.598 NM_027626
Psd3
pleckstrin and Sec7 domain containing 3
chr4_-_82151180 5.597 NM_001113209
NM_001113210
NM_008687
Nfib


nuclear factor I/B


chr18_+_23910833 5.509 NM_001162942
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr6_-_72566993 5.479 NM_009443
Tgoln1
trans-golgi network protein
chr13_+_98011057 5.472 NM_007930
Enc1
ectodermal-neural cortex 1
chr6_-_119146426 5.458 NM_009781
Cacna1c
calcium channel, voltage-dependent, L type, alpha 1C subunit
chr5_-_149364353 5.444 NM_011908
Ubl3
ubiquitin-like 3
chr11_-_7113899 5.439 NM_008343
Igfbp3
insulin-like growth factor binding protein 3
chr5_-_76733540 5.435 NM_007715
Clock
circadian locomotor output cycles kaput
chr6_-_119058206 5.395 NM_001159533
NM_001159534
NM_001159535
Cacna1c


calcium channel, voltage-dependent, L type, alpha 1C subunit


chr14_-_66832383 5.353 NM_001162366
Ptk2b
PTK2 protein tyrosine kinase 2 beta
chr18_-_67712374 5.352 NM_194355
Spire1
spire homolog 1 (Drosophila)
chr8_+_124254462 5.351 NM_020605
Jph3
junctophilin 3
chr18_+_23573908 5.297 NM_010087
NM_207650
Dtna

dystrobrevin alpha

chr2_-_173102033 5.281 NM_022995
Pmepa1
prostate transmembrane protein, androgen induced 1
chr8_-_37796104 5.260 NM_001194941
Dlc1
deleted in liver cancer 1
chr6_+_4853319 5.241 NM_181595
Ppp1r9a
protein phosphatase 1, regulatory (inhibitor) subunit 9A
chr13_+_48356795 5.110 NM_031166
Id4
inhibitor of DNA binding 4
chr6_-_12699189 5.099 NM_001164805
Thsd7a
thrombospondin, type I, domain containing 7A
chr4_-_141795288 5.039 NM_001109685
9030409G11Rik
RIKEN cDNA 9030409G11 gene
chr8_-_25549415 4.996 NM_026931
1810011O10Rik
RIKEN cDNA 1810011O10 gene
chr17_+_14416508 4.942 NM_022315
Smoc2
SPARC related modular calcium binding 2
chr12_+_30213224 4.941 NM_001093775
NM_001093778
NM_008666
Myt1l


myelin transcription factor 1-like


chr2_+_71819264 4.932 NM_019688
Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr1_+_137662648 4.887 NM_013750
Phlda3
pleckstrin homology-like domain, family A, member 3
chr6_-_72566691 4.845 NM_009444
Tgoln1
Tgoln2
trans-golgi network protein
trans-golgi network protein 2
chr8_-_8660610 4.844 NM_010111
Efnb2
ephrin B2
chr16_-_22439642 4.831 NM_023794
Etv5
ets variant gene 5
chr2_-_157392026 4.826 NM_016916
Blcap
bladder cancer associated protein homolog (human)
chr1_-_154472199 4.807 NM_016846
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr4_+_13711928 4.799 NM_009822
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr10_+_105907394 4.797 NM_177373
Ppfia2
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2
chr5_+_19413335 4.796 NM_001170745
NM_015823
Magi2

membrane associated guanylate kinase, WW and PDZ domain containing 2

chr10_-_18463500 4.664 NM_001033258
D10Bwg1379e
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr19_+_56796861 4.657 NM_007419
Adrb1
adrenergic receptor, beta 1
chr8_-_37676995 4.645 NM_015802
Dlc1
deleted in liver cancer 1
chr15_+_99223377 4.582 NM_001171034
NM_001171036
NM_026669
Tmbim6


transmembrane BAX inhibitor motif containing 6


chr11_-_86570918 4.574 NM_001003908
Cltc
clathrin, heavy polypeptide (Hc)
chr12_-_25780932 4.567 NM_010496
Id2
inhibitor of DNA binding 2
chr18_+_23962468 4.519 NM_153058
Mapre2
microtubule-associated protein, RP/EB family, member 2
chr1_+_39251056 4.467 NM_008719
Npas2
neuronal PAS domain protein 2
chr18_+_37112301 4.424 NM_001174154
NM_007766
Pcdha4-g
Pcdha4
protocadherin alpha 4-gamma
protocadherin alpha 4
chr7_+_48154647 4.392 NM_021387
Vstm2b
V-set and transmembrane domain containing 2B
chr15_-_58654964 4.329 NM_175212
Tmem65
transmembrane protein 65
chr17_+_87506971 4.326 NM_019654
Socs5
suppressor of cytokine signaling 5
chr16_+_21204820 4.300 NM_010143
Ephb3
Eph receptor B3
chr2_+_65508501 4.300 NM_001099298
Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chrX_+_53862956 4.292 NM_172780
Slc9a6
solute carrier family 9 (sodium/hydrogen exchanger), member 6
chr8_+_81552335 4.274 NM_178267
Zfp827
zinc finger protein 827
chr14_-_66899764 4.246 NM_001162365
NM_172498
Ptk2b

PTK2 protein tyrosine kinase 2 beta

chrX_-_20498021 4.238 NM_001110780
NM_013680
Syn1

synapsin I

chr11_-_11937330 4.228 NM_010345
Grb10
growth factor receptor bound protein 10
chr2_+_76244578 4.211 NM_145525
Osbpl6
oxysterol binding protein-like 6
chr15_+_99223622 4.196 NM_001171035
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr11_+_42233258 4.169 NM_008070
Gabrb2
gamma-aminobutyric acid (GABA) A receptor, subunit beta 2
chr4_+_13670425 4.139 NM_001111026
Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr12_+_30219769 4.103 NM_001093776
Myt1l
myelin transcription factor 1-like
chr7_+_107376116 4.092 NM_027629
Pgm2l1
phosphoglucomutase 2-like 1
chr7_-_74517624 4.085 NM_001033713
Mef2a
myocyte enhancer factor 2A
chr9_-_16182674 4.079 NM_001080814
Fat3
FAT tumor suppressor homolog 3 (Drosophila)
chr16_-_28929698 4.044 NM_177718
1600021P15Rik
RIKEN cDNA 1600021P15 gene
chr11_+_59475986 4.013 NM_012027
NM_201245
Mprip

myosin phosphatase Rho interacting protein

chr12_+_85455277 4.011 NM_028821
Dnalc1
dynein, axonemal, light chain 1
chr2_+_19579607 3.964 NM_027715
Otud1
OTU domain containing 1
chr9_-_105397342 3.941 NM_175025
Atp2c1
ATPase, Ca++-sequestering
chr6_+_86388364 3.930 NM_146170
C87436
expressed sequence C87436
chr2_+_124436031 3.929 NM_172537
NM_199238
NM_199239
NM_199240
NM_199241
Sema6d




sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D




chr5_+_111847185 3.915 NM_001081235
Mn1
meningioma 1
chr9_+_58430031 3.912 NM_009145
Nptn
neuroplastin
chr6_+_15135505 3.876 NM_212435
Foxp2
forkhead box P2
chr4_-_151235861 3.859 NM_001081557
NM_001195565
Camta1

calmodulin binding transcription activator 1

chr2_+_118502976 3.783 NM_001145854
Pak6
p21 protein (Cdc42/Rac)-activated kinase 6
chr8_-_42140113 3.762 NM_001005864
Mtus1
mitochondrial tumor suppressor 1
chr5_-_53604673 3.760 NM_172710
Sel1l3
sel-1 suppressor of lin-12-like 3 (C. elegans)
chr15_-_39775173 3.734 NM_172814
Lrp12
low density lipoprotein-related protein 12
chr3_+_122432075 3.729 NM_153422
Pde5a
phosphodiesterase 5A, cGMP-specific
chr4_+_97444312 3.725 NM_001122953
NM_010905
Nfia

nuclear factor I/A

chr18_+_3507920 3.580 NM_026505
Bambi
BMP and activin membrane-bound inhibitor, homolog (Xenopus laevis)

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
2.61 2.32e-09 GO:0007399 nervous system development
1.71 3.22e-06 GO:0051179 localization
1.81 1.45e-05 GO:0048731 system development
1.75 2.31e-05 GO:0006810 transport
1.74 2.63e-05 GO:0051234 establishment of localization
2.29 6.11e-05 GO:0035556 intracellular signal transduction
1.65 1.83e-04 GO:0007275 multicellular organismal development
2.14 2.11e-04 GO:0009966 regulation of signal transduction
2.01 2.66e-04 GO:0023051 regulation of signaling
1.59 5.25e-04 GO:0032502 developmental process
1.64 1.15e-03 GO:0048856 anatomical structure development
1.62 1.47e-03 GO:0048518 positive regulation of biological process
1.86 2.15e-03 GO:0048583 regulation of response to stimulus
2.30 3.47e-03 GO:0048699 generation of neurons
2.48 3.48e-03 GO:0048878 chemical homeostasis
2.21 6.22e-03 GO:0022008 neurogenesis
2.76 7.12e-03 GO:0016044 cellular membrane organization
2.75 7.76e-03 GO:0061024 membrane organization
2.81 8.25e-03 GO:0045597 positive regulation of cell differentiation
2.42 8.27e-03 GO:0016192 vesicle-mediated transport
2.70 1.04e-02 GO:0006873 cellular ion homeostasis
3.47 1.27e-02 GO:0006897 endocytosis
3.47 1.27e-02 GO:0010324 membrane invagination
2.66 1.38e-02 GO:0007417 central nervous system development
1.59 1.49e-02 GO:0048522 positive regulation of cellular process
2.63 1.62e-02 GO:0055082 cellular chemical homeostasis
2.57 1.65e-02 GO:0050801 ion homeostasis
1.97 1.96e-02 GO:0010646 regulation of cell communication
2.87 2.22e-02 GO:0007420 brain development
2.14 2.86e-02 GO:0045595 regulation of cell differentiation
2.67 2.88e-02 GO:0060284 regulation of cell development
2.41 3.64e-02 GO:0051094 positive regulation of developmental process
1.64 3.75e-02 GO:0048869 cellular developmental process
3.19 3.91e-02 GO:0051056 regulation of small GTPase mediated signal transduction
1.64 4.92e-02 GO:0030154 cell differentiation

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
2.94 3.96e-11 GO:0005626 insoluble fraction
2.97 7.00e-11 GO:0005624 membrane fraction
1.75 1.29e-09 GO:0071944 cell periphery
2.54 1.35e-09 GO:0000267 cell fraction
1.74 2.80e-09 GO:0005886 plasma membrane
1.17 1.60e-07 GO:0005623 cell
1.17 1.60e-07 GO:0044464 cell part
3.13 2.00e-06 GO:0045202 synapse
1.94 6.02e-06 GO:0044459 plasma membrane part
1.33 6.48e-06 GO:0016020 membrane
2.74 7.98e-06 GO:0030054 cell junction
1.32 2.42e-05 GO:0005737 cytoplasm
3.12 3.91e-04 GO:0044456 synapse part
2.12 7.13e-04 GO:0005794 Golgi apparatus
1.20 1.73e-03 GO:0005622 intracellular
4.02 5.40e-03 GO:0030136 clathrin-coated vesicle
6.69 5.52e-03 GO:0030665 clathrin coated vesicle membrane
1.28 6.92e-03 GO:0044425 membrane part
2.28 1.17e-02 GO:0043005 neuron projection
3.54 2.06e-02 GO:0030135 coated vesicle
4.84 2.39e-02 GO:0030427 site of polarized growth
5.16 3.68e-02 GO:0030662 coated vesicle membrane
1.16 4.92e-02 GO:0044424 intracellular part

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.59 7.22e-11 GO:0005515 protein binding
1.27 7.81e-07 GO:0005488 binding
3.37 4.18e-06 GO:0030695 GTPase regulator activity
3.27 8.16e-06 GO:0060589 nucleoside-triphosphatase regulator activity
4.22 2.03e-04 GO:0005543 phospholipid binding
5.44 2.43e-04 GO:0035091 phosphatidylinositol binding
2.96 2.92e-04 GO:0008289 lipid binding
2.14 2.20e-03 GO:0019899 enzyme binding
2.50 3.00e-03 GO:0008092 cytoskeletal protein binding
3.23 4.37e-03 GO:0005083 small GTPase regulator activity
4.05 6.52e-03 GO:0005085 guanyl-nucleotide exchange factor activity
2.37 1.04e-02 GO:0019904 protein domain specific binding
2.86 1.35e-02 GO:0019900 kinase binding
3.06 1.48e-02 GO:0019901 protein kinase binding
3.29 1.81e-02 GO:0005096 GTPase activator activity
1.95 4.38e-02 GO:0030234 enzyme regulator activity
13.89 4.50e-02 GO:0015085 calcium ion transmembrane transporter activity