• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: HIC1.p2

Z-value: 1.783

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr13_-_78337844	46.185		Nr2f1	nuclear receptor subfamily 2, group F, member 1
chr13_-_78338131	34.734	NM_010151	Nr2f1	nuclear receptor subfamily 2, group F, member 1
chrX_+_53984926	25.322	NM_010211	Fhl1	four and a half LIM domains 1
chrX_+_53985133	21.727	NM_001077361	Fhl1	four and a half LIM domains 1
chr2_+_28061156	21.642	NM_001038612 NM_019498	Olfm1	olfactomedin 1
chr11_+_6963421	19.731	NM_009622	Adcy1	adenylate cyclase 1
chr9_+_60560734	18.030		Larp6	La ribonucleoprotein domain family, member 6
chr3_-_125641429	17.188	NM_011674	Ugt8a	UDP galactosyltransferase 8A
chr4_+_138011061	16.976	NM_025451	Camk2n1	calcium/calmodulin-dependent protein kinase II inhibitor 1
chr9_+_60560923	16.228	NM_026235	Larp6	La ribonucleoprotein domain family, member 6
chr11_-_5965743	15.820	NM_001174053 NM_001174054 NM_007595	Camk2b	calcium/calmodulin-dependent protein kinase II, beta
chr8_+_86424565	15.614		Lphn1	latrophilin 1
chr2_+_164312023	15.050		Dbndd2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr6_+_115085096	15.008		Syn2	synapsin II
chr2_+_164312087	14.740		Dbndd2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr4_-_151235861	14.404	NM_001081557 NM_001195565	Camta1	calmodulin binding transcription activator 1
chr10_-_75807976	14.325	NM_001081419	Dip2a	DIP2 disco-interacting protein 2 homolog A (Drosophila)
chr12_+_113960424	14.146		AW555464	expressed sequence AW555464
chr12_+_50484907	13.999		Foxg1	forkhead box G1
chr8_-_87323896	13.257		Nfix	nuclear factor I/X
chr19_-_5085471	13.124	NM_001001885	Tmem151a	transmembrane protein 151A
chr1_-_194681914	13.120	NM_198247	Sertad4	SERTA domain containing 4
chr5_+_110973321	12.910	NM_198306	Galnt9	UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9
chr12_+_113960530	12.900		AW555464	expressed sequence AW555464
chr11_-_5965544	12.869		Camk2b	calcium/calmodulin-dependent protein kinase II, beta
chr2_-_80421054	12.741	NM_016965	Nckap1	NCK-associated protein 1
chr5_+_37633353	12.505		Crmp1	collapsin response mediator protein 1
chr5_+_37633317	12.461	NM_001136058	Crmp1	collapsin response mediator protein 1
chr19_-_5085487	12.459		Tmem151a	transmembrane protein 151A
chr5_+_37259906	12.442		Ppp2r2c	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr8_+_129587894	12.431	NM_001122850 NM_033620	Pard3	par-3 (partitioning defective 3) homolog (C. elegans)
chr2_+_119625463	12.402		Tyro3	TYRO3 protein tyrosine kinase 3
chr14_-_66572577	12.021	NM_172604	Scara3	scavenger receptor class A, member 3
chr8_-_87323958	11.773		Nfix	nuclear factor I/X
chr15_+_87455659	11.640	NM_134096	Fam19a5	family with sequence similarity 19, member A5
chr11_+_83223154	11.638		Rasl10b	RAS-like, family 10, member B
chr15_+_87374667	11.607		Fam19a5	family with sequence similarity 19, member A5
chr16_-_4420415	11.508		Adcy9	adenylate cyclase 9
chr13_-_52626022	11.507		Diras2	DIRAS family, GTP-binding RAS-like 2
chr4_-_154735351	11.218	NM_008860	Prkcz	protein kinase C, zeta
chr17_+_25945986	11.136	NM_001164225	Fbxl16	F-box and leucine-rich repeat protein 16
chr2_+_28048592	11.126	NM_001038613 NM_001038614	Olfm1	olfactomedin 1
chr4_+_129662110	11.125		Bai2	brain-specific angiogenesis inhibitor 2
chr2_-_32702610	11.119		Stxbp1	syntaxin binding protein 1
chr10_-_80945379	11.063		Celf5	CUGBP, Elav-like family member 5
chr15_+_68758773	11.009	NM_010158	Khdrbs3	KH domain containing, RNA binding, signal transduction associated 3
chr7_+_71646515	10.894	NM_007461	Apba2	amyloid beta (A4) precursor protein-binding, family A, member 2
chr2_+_28048779	10.891		Olfm1	olfactomedin 1
chr12_+_113960379	10.874	NM_001024602	AW555464	expressed sequence AW555464
chr5_-_21850490	10.846	NM_011261	Reln	reelin
chr16_-_85173851	10.800		App	amyloid beta (A4) precursor protein
chr7_+_25266986	10.650	NM_153112	Cadm4	cell adhesion molecule 4
chr9_-_91259829	10.616		Zic1	zinc finger protein of the cerebellum 1
chr6_+_71657791	10.595	NM_178608	Reep1	receptor accessory protein 1
chr13_-_69877709	10.590		Ube2ql1	ubiquitin-conjugating enzyme E2Q family-like 1
chr6_+_117961386	10.506		Rasgef1a	RasGEF domain family, member 1A
chr11_+_83223573	10.502	NM_001013386	Rasl10b	RAS-like, family 10, member B
chr10_+_61245998	10.425
chr17_-_66799086	10.367	NM_001114098 NM_172963	1110012J17Rik	RIKEN cDNA 1110012J17 gene
chr15_-_90880241	10.322	NM_001109040 NM_001109041 NM_001109042 NM_016705	Kif21a	kinesin family member 21A
chr9_+_103014279	10.267		Rab6b	RAB6B, member RAS oncogene family
chr8_-_47296201	10.248	NM_007450	Slc25a4	solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr2_-_32702729	10.189	NM_009295 NM_001113569	Stxbp1	syntaxin binding protein 1
chr8_+_32200076	10.054	NM_025869	Dusp26	dual specificity phosphatase 26 (putative)
chr8_-_67373608	9.816		Klhl2	kelch-like 2, Mayven (Drosophila)
chr18_-_16967754	9.755		Cdh2	cadherin 2
chr9_-_97933599	9.754		Clstn2	calsyntenin 2
chr16_-_85173918	9.749		App	amyloid beta (A4) precursor protein
chr18_+_58038278	9.718	NM_009194	Slc12a2	solute carrier family 12, member 2
chr15_-_25343483	9.628	NM_027395	Basp1	brain abundant, membrane attached signal protein 1
chr16_-_85173930	9.525		App	amyloid beta (A4) precursor protein
chr1_-_33964439	9.505	NM_177235	Bend6	BEN domain containing 6
chr4_-_81088575	9.468	NM_010820	Mpdz	multiple PDZ domain protein
chr5_-_139605617	9.467	NM_008923	Prkar1b	protein kinase, cAMP dependent regulatory, type I beta
chr15_-_75397601	9.442	NM_011837	Ly6h	lymphocyte antigen 6 complex, locus H
chr13_-_95992547	9.398		Pde8b	phosphodiesterase 8B
chr13_+_104899869	9.295	NM_144838	Sgtb	small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr6_+_22825464	9.291	NM_001081306	Ptprz1	protein tyrosine phosphatase, receptor type Z, polypeptide 1
chr2_-_151458299	9.284		Snph	syntaphilin
chr19_-_40588193	9.281		Sorbs1	sorbin and SH3 domain containing 1
chr4_+_129662284	9.227	NM_173071	Bai2	brain-specific angiogenesis inhibitor 2
chr14_-_19726121	9.188	NM_144839	Ube2e2	ubiquitin-conjugating enzyme E2E 2 (UBC4/5 homolog, yeast)
chr13_+_97841524	9.165	NM_001100458	Fam169a	family with sequence similarity 169, member A
chr13_+_104899814	9.058		Sgtb	small glutamine-rich tetratricopeptide repeat (TPR)-containing, beta
chr13_+_58907999	9.028		Ntrk2	neurotrophic tyrosine kinase, receptor, type 2
chr16_-_85173978	9.022		App	amyloid beta (A4) precursor protein
chr10_-_80945445	9.010	NM_176954	Celf5	CUGBP, Elav-like family member 5
chr2_+_119625249	8.956	NM_019392	Tyro3	TYRO3 protein tyrosine kinase 3
chr8_+_128822478	8.932	NM_175434	Slc35f3	solute carrier family 35, member F3
chr7_+_149135647	8.890	NM_029426	Brsk2	BR serine/threonine kinase 2
chr11_-_5965555	8.846		Camk2b	calcium/calmodulin-dependent protein kinase II, beta
chr11_-_69419330	8.819		Atp1b2	ATPase, Na+/K+ transporting, beta 2 polypeptide
chr2_+_148221069	8.799		Sstr4	somatostatin receptor 4
chr9_-_97933533	8.753	NM_022319	Clstn2	calsyntenin 2
chr1_+_72871060	8.748	NM_008342	Igfbp2	insulin-like growth factor binding protein 2
chr7_+_29052821	8.725	NM_198425	Eid2	EP300 interacting inhibitor of differentiation 2
chr5_+_34064372	8.684	NM_008010 NM_001163215	Fgfr3	fibroblast growth factor receptor 3
chr9_+_110147867	8.671		Cspg5	chondroitin sulfate proteoglycan 5
chr1_-_159342713	8.592	NM_177644	Rasal2	RAS protein activator like 2
chr8_-_88224652	8.564		Neto2	neuropilin (NRP) and tolloid (TLL)-like 2
chr5_-_31597792	8.514	NM_022424	Fndc4	fibronectin type III domain containing 4
chr9_+_95538038	8.465	NM_029620	Pcolce2	procollagen C-endopeptidase enhancer 2
chr15_-_77137015	8.432		Rbfox2	RNA binding protein, fox-1 homolog (C. elegans) 2
chr2_-_25978296	8.431		Nacc2	nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr16_-_85173944	8.383	NM_001198823 NM_001198824 NM_001198825 NM_001198826 NM_007471	App	amyloid beta (A4) precursor protein
chr5_-_52957466	8.341		Lgi2	leucine-rich repeat LGI family, member 2
chr2_-_77654669	8.302	NM_178723	Zfp385b	zinc finger protein 385B
chr9_+_72510153	8.297	NM_010890	Nedd4	neural precursor cell expressed, developmentally down-regulated 4
chr2_-_32208737	8.274	NM_010065	Dnm1	dynamin 1
chr3_+_34549057	8.270		Sox2	SRY-box containing gene 2
chr2_-_5635517	8.224		Camk1d	calcium/calmodulin-dependent protein kinase ID
chr16_+_37777075	8.187	NM_008047	Fstl1	follistatin-like 1
chr2_+_132607398	8.126		Chgb	chromogranin B
chr2_-_151458256	8.118	NM_198214	Snph	syntaphilin
chr8_+_73278577	8.057	NM_001166399 NM_009001	Rab3a	RAB3A, member RAS oncogene family
chr18_-_16967557	7.954	NM_007664	Cdh2	cadherin 2
chr2_+_132607408	7.907		Chgb	chromogranin B
chr10_-_79602040	7.897		Dos	downstream of Stk11
chr19_-_40588235	7.892		Sorbs1	sorbin and SH3 domain containing 1
chr2_+_164311755	7.873	NM_026797	Dbndd2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr17_+_25854116	7.863	NM_022422	Gng13	guanine nucleotide binding protein (G protein), gamma 13
chr13_+_58907929	7.852		Ntrk2	neurotrophic tyrosine kinase, receptor, type 2
chr4_-_11893500	7.839	NM_001033453 NM_001098230	Pdp1	pyruvate dehyrogenase phosphatase catalytic subunit 1
chr3_+_69120782	7.825	NM_178726	Ppm1l	protein phosphatase 1 (formerly 2C)-like
chr2_-_168567436	7.777		Atp9a	ATPase, class II, type 9A
chr10_+_12810593	7.774	NM_009538	Plagl1	pleiomorphic adenoma gene-like 1
chr2_+_132607013	7.772	NM_007694	Chgb	chromogranin B
chr2_+_164311639	7.747	NM_001048227	Dbndd2	dysbindin (dystrobrevin binding protein 1) domain containing 2
chr5_+_15440508	7.741	NM_001110843 NM_001110844 NM_001110845 NM_001110846 NM_009784	Cacna2d1	calcium channel, voltage-dependent, alpha2/delta subunit 1
chr12_+_109661287	7.738		Eml1	echinoderm microtubule associated protein like 1
chr8_+_24521967	7.681	NM_013834	Sfrp1	secreted frizzled-related protein 1
chr2_+_132607432	7.661		Chgb	chromogranin B
chrX_-_132602648	7.653	NM_009749	Bex2	brain expressed X-linked 2
chr16_-_52452766	7.652		Alcam	activated leukocyte cell adhesion molecule
chr11_-_116442760	7.575	NM_173755	Ube2o	ubiquitin-conjugating enzyme E2O
chr19_+_10463540	7.564	NM_018801 NM_173067 NM_173068	Syt7	synaptotagmin VII
chr8_+_86423968	7.524	NM_181039	Lphn1	latrophilin 1
chr5_+_74591336	7.507	NM_026878	Rasl11b	RAS-like, family 11, member B
chr14_+_28435613	7.490	NM_177814	Erc2	ELKS/RAB6-interacting/CAST family member 2
chr4_+_84851330	7.484	NM_019535	Sh3gl2	SH3-domain GRB2-like 2
chr6_+_115084919	7.449	NM_001111015 NM_013681	Syn2	synapsin II
chr14_-_46149660	7.417	NM_146054	Fermt2	fermitin family homolog 2 (Drosophila)
chr9_-_41932195	7.405		Sorl1	sortilin-related receptor, LDLR class A repeats-containing
chr12_-_51750204	7.398	NM_008858	Prkd1	protein kinase D1
chr10_-_83111346	7.392	NM_145220	Appl2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr5_+_34339551	7.389		Nat8l	N-acetyltransferase 8-like
chr5_+_37259780	7.387	NM_172994	Ppp2r2c	protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), gamma isoform
chr10_-_31329530	7.351	NM_001146349	Rnf217	ring finger protein 217
chr1_-_37776633	7.325	NM_028096	2010300C02Rik	RIKEN cDNA 2010300C02 gene
chr7_+_106416854	7.305	NM_001043355	Mtap6	microtubule-associated protein 6
chr1_-_89406861	7.304	NM_019867	Ngef	neuronal guanine nucleotide exchange factor
chr11_-_90252208	7.264		Hlf	hepatic leukemia factor
chr11_-_118216591	7.230		Timp2	tissue inhibitor of metalloproteinase 2
chr2_-_165060188	7.224	NM_174988	Cdh22	cadherin 22
chr4_-_140616455	7.215	NM_001145958	Crocc	ciliary rootlet coiled-coil, rootletin
chr3_-_119486136	7.192		Ptbp2	polypyrimidine tract binding protein 2
chr1_+_34068669	7.168	NM_133833 NM_134448	Dst	dystonin
chr3_-_119486305	7.160	NM_019550	Ptbp2	polypyrimidine tract binding protein 2
chr7_-_88599560	7.108	NM_007755	Cpeb1	cytoplasmic polyadenylation element binding protein 1
chr12_+_75098739	7.096	NM_172804	Syt16	synaptotagmin XVI
chr4_+_148960536	7.088		Clstn1	calsyntenin 1
chr13_+_9275741	7.086	NM_001081426	Dip2c	DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr17_+_78599556	7.050	NM_015800	Crim1	cysteine rich transmembrane BMP regulator 1 (chordin like)
chr9_-_14185399	7.036		Endod1	endonuclease domain containing 1
chr13_-_100286521	6.975	NM_008634	Mtap1b	microtubule-associated protein 1B
chr11_-_118216689	6.889	NM_011594	Timp2	tissue inhibitor of metalloproteinase 2
chr9_+_75473524	6.875	NM_027309	Lysmd2	LysM, putative peptidoglycan-binding, domain containing 2
chr5_+_74591290	6.857		Rasl11b	RAS-like, family 11, member B
chr7_-_137410321	6.845	NM_010207 NM_201601	Fgfr2	fibroblast growth factor receptor 2
chr4_+_48598013	6.821	NM_021436	Tmeff1	transmembrane protein with EGF-like and two follistatin-like domains 1
chr2_+_28048511	6.821		Olfm1	olfactomedin 1
chr10_+_7309565	6.818	NM_172784	Lrp11	low density lipoprotein receptor-related protein 11
chr2_+_124436031	6.804	NM_172537 NM_199238 NM_199239 NM_199240 NM_199241	Sema6d	sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr2_-_25978328	6.781	NM_026495	Nacc2	nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr17_-_26338106	6.773		Arhgdig	Rho GDP dissociation inhibitor (GDI) gamma
chr4_+_155068604	6.762		B930041F14Rik	RIKEN cDNA B930041F14 gene
chr19_-_24299389	6.751		Tjp2	tight junction protein 2
chr11_-_80966253	6.685	NM_007384	Accn1	amiloride-sensitive cation channel 1, neuronal (degenerin)
chr14_-_57752102	6.668		Gjb6	gap junction protein, beta 6
chr5_+_14514906	6.638	NM_001110796 NM_011995	Pclo	piccolo (presynaptic cytomatrix protein)
chr11_-_116274124	6.637		Rnf157	ring finger protein 157
chr4_-_138648762	6.633	NM_008675	Nbl1	neuroblastoma, suppression of tumorigenicity 1
chr2_+_164793698	6.611		Slc12a5	solute carrier family 12, member 5
chr5_+_34339258	6.521		Nat8l	N-acetyltransferase 8-like
chrX_-_159081510	6.493	NM_178256	Reps2	RALBP1 associated Eps domain containing protein 2
chr10_-_115910911	6.467		Kcnmb4	potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr15_+_99421458	6.431	NM_009701	Aqp5	aquaporin 5
chr19_+_47089168	6.429	NM_146100	Ina	internexin neuronal intermediate filament protein, alpha
chr8_-_112692071	6.382	NM_007586	Calb2	calbindin 2
chr13_+_58907953	6.373	NM_008745	Ntrk2	neurotrophic tyrosine kinase, receptor, type 2
chr9_+_103014374	6.369	NM_173781	Rab6b	RAB6B, member RAS oncogene family
chr16_+_90386629	6.357	NM_015755	Hunk	hormonally upregulated Neu-associated kinase
chr13_-_52626065	6.347	NM_001024474	Diras2	DIRAS family, GTP-binding RAS-like 2
chr5_-_122951791	6.335		Atp2a2	ATPase, Ca++ transporting, cardiac muscle, slow twitch 2
chr2_+_164793487	6.331	NM_020333	Slc12a5	solute carrier family 12, member 5
chr2_+_25258653	6.331		Npdc1	neural proliferation, differentiation and control gene 1
chr9_+_110148568	6.292		Cspg5	chondroitin sulfate proteoglycan 5
chr10_-_42893894	6.282		Sobp	sine oculis-binding protein homolog (Drosophila)
chr4_+_13670582	6.272		Runx1t1	runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr3_+_17954324	6.262	NM_021560	Bhlhe22	basic helix-loop-helix family, member e22

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.94	5.58e-32	GO:0007399	nervous system development
1.97	1.61e-21	GO:0048699	generation of neurons
1.91	3.83e-20	GO:0022008	neurogenesis
1.41	1.11e-19	GO:0051179	localization
1.47	1.12e-18	GO:0048731	system development
1.42	1.66e-18	GO:0007275	multicellular organismal development
1.39	3.51e-18	GO:0032502	developmental process
1.63	7.38e-18	GO:0023051	regulation of signaling
1.43	1.15e-17	GO:0048856	anatomical structure development
1.43	4.48e-17	GO:0006810	transport
1.42	5.73e-17	GO:0051234	establishment of localization
2.36	1.01e-16	GO:0031175	neuron projection development
2.29	2.25e-15	GO:0019226	transmission of nerve impulse
2.29	2.25e-15	GO:0035637	multicellular organismal signaling
2.14	2.97e-15	GO:0048666	neuron development
1.98	1.27e-14	GO:0030182	neuron differentiation
2.45	2.97e-14	GO:0048812	neuron projection morphogenesis
2.02	3.16e-14	GO:0030030	cell projection organization
1.62	4.68e-14	GO:0009966	regulation of signal transduction
2.29	6.73e-14	GO:0048858	cell projection morphogenesis
1.57	8.13e-14	GO:0009653	anatomical structure morphogenesis
2.26	1.09e-13	GO:0032990	cell part morphogenesis
2.11	1.12e-13	GO:0060284	regulation of cell development
2.13	5.75e-13	GO:0051960	regulation of nervous system development
2.19	7.34e-13	GO:0050767	regulation of neurogenesis
1.44	9.25e-13	GO:0048869	cellular developmental process
2.48	1.18e-12	GO:0007409	axonogenesis
2.30	2.20e-12	GO:0045664	regulation of neuron differentiation
1.44	2.41e-12	GO:0030154	cell differentiation
1.35	6.42e-12	GO:0016043	cellular component organization
1.99	1.01e-11	GO:0000902	cell morphogenesis
1.79	1.42e-11	GO:0007154	cell communication
2.34	1.64e-11	GO:0048667	cell morphogenesis involved in neuron differentiation
1.93	2.57e-11	GO:0032989	cellular component morphogenesis
1.40	2.74e-11	GO:0071842	cellular component organization at cellular level
1.67	4.83e-11	GO:0048468	cell development
2.59	5.53e-11	GO:0010975	regulation of neuron projection development
1.67	1.13e-10	GO:0051128	regulation of cellular component organization
1.32	1.14e-10	GO:0071840	cellular component organization or biogenesis
2.24	1.22e-10	GO:0007268	synaptic transmission
2.13	1.53e-10	GO:0000904	cell morphogenesis involved in differentiation
1.35	4.61e-10	GO:0048522	positive regulation of cellular process
1.67	5.39e-10	GO:0045595	regulation of cell differentiation
1.56	6.58e-10	GO:0010646	regulation of cell communication
2.39	7.16e-10	GO:0031344	regulation of cell projection organization
1.37	1.00e-09	GO:0071841	cellular component organization or biogenesis at cellular level
2.03	1.47e-09	GO:0007420	brain development
1.55	5.31e-09	GO:0050793	regulation of developmental process
1.31	6.28e-09	GO:0048518	positive regulation of biological process
1.54	7.74e-09	GO:0035556	intracellular signal transduction
2.18	8.85e-09	GO:0051056	regulation of small GTPase mediated signal transduction
1.85	1.33e-08	GO:0007417	central nervous system development
1.42	1.69e-08	GO:0048583	regulation of response to stimulus
1.71	2.14e-08	GO:0016192	vesicle-mediated transport
2.39	2.87e-08	GO:0042391	regulation of membrane potential
1.43	5.90e-08	GO:0065009	regulation of molecular function
1.84	1.04e-07	GO:0007267	cell-cell signaling
1.55	2.09e-07	GO:2000026	regulation of multicellular organismal development
1.23	2.36e-07	GO:0019222	regulation of metabolic process
2.44	2.52e-07	GO:0010769	regulation of cell morphogenesis involved in differentiation
2.44	2.52e-07	GO:0022604	regulation of cell morphogenesis
1.50	3.12e-07	GO:0032879	regulation of localization
1.51	3.26e-07	GO:0006796	phosphate metabolic process
2.16	3.41e-07	GO:0046578	regulation of Ras protein signal transduction
1.24	3.90e-07	GO:0031323	regulation of cellular metabolic process
1.50	3.99e-07	GO:0006793	phosphorus metabolic process
1.30	9.73e-07	GO:0048519	negative regulation of biological process
1.32	1.06e-06	GO:0048523	negative regulation of cellular process
1.49	1.08e-06	GO:0051641	cellular localization
1.50	1.99e-06	GO:0032268	regulation of cellular protein metabolic process
1.52	2.95e-06	GO:0051649	establishment of localization in cell
1.60	5.52e-06	GO:0042325	regulation of phosphorylation
3.58	6.55e-06	GO:0050773	regulation of dendrite development
1.79	6.92e-06	GO:0007610	behavior
1.59	7.26e-06	GO:0019220	regulation of phosphate metabolic process
1.59	7.26e-06	GO:0051174	regulation of phosphorus metabolic process
1.46	1.01e-05	GO:0008104	protein localization
1.37	1.25e-05	GO:0051239	regulation of multicellular organismal process
1.54	1.49e-05	GO:0051049	regulation of transport
1.22	1.66e-05	GO:0080090	regulation of primary metabolic process
1.33	1.69e-05	GO:0065008	regulation of biological quality
2.00	2.17e-05	GO:0051129	negative regulation of cellular component organization
1.76	2.30e-05	GO:0045859	regulation of protein kinase activity
1.53	2.53e-05	GO:0031399	regulation of protein modification process
1.58	2.85e-05	GO:0007155	cell adhesion
1.41	3.14e-05	GO:0050790	regulation of catalytic activity
1.41	3.25e-05	GO:0033036	macromolecule localization
2.00	3.30e-05	GO:0030900	forebrain development
1.60	3.37e-05	GO:0001932	regulation of protein phosphorylation
1.62	4.37e-05	GO:0023056	positive regulation of signaling
1.57	5.06e-05	GO:0022610	biological adhesion
1.62	5.68e-05	GO:0010647	positive regulation of cell communication
2.76	6.06e-05	GO:0001505	regulation of neurotransmitter levels
1.50	6.37e-05	GO:0015031	protein transport
1.71	6.66e-05	GO:0043549	regulation of kinase activity
1.77	6.86e-05	GO:0022603	regulation of anatomical structure morphogenesis
1.49	6.97e-05	GO:0045184	establishment of protein localization
1.42	7.17e-05	GO:0051246	regulation of protein metabolic process
2.84	1.35e-04	GO:0017157	regulation of exocytosis
1.47	1.54e-04	GO:0016310	phosphorylation
1.67	1.76e-04	GO:0051338	regulation of transferase activity
1.21	1.88e-04	GO:0060255	regulation of macromolecule metabolic process
1.92	2.31e-04	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway
1.62	2.62e-04	GO:0009967	positive regulation of signal transduction
1.14	3.51e-04	GO:0044237	cellular metabolic process
2.89	4.37e-04	GO:0031345	negative regulation of cell projection organization
1.89	4.53e-04	GO:0031644	regulation of neurological system process
1.84	4.87e-04	GO:0045860	positive regulation of protein kinase activity
1.93	5.06e-04	GO:0051969	regulation of transmission of nerve impulse
1.70	6.10e-04	GO:0007167	enzyme linked receptor protein signaling pathway
2.30	6.54e-04	GO:0021537	telencephalon development
1.80	6.61e-04	GO:0007264	small GTPase mediated signal transduction
3.58	7.17e-04	GO:0048814	regulation of dendrite morphogenesis
2.45	7.39e-04	GO:0006836	neurotransmitter transport
1.80	8.60e-04	GO:0033674	positive regulation of kinase activity
1.95	9.77e-04	GO:0050804	regulation of synaptic transmission
1.29	1.00e-03	GO:0043412	macromolecule modification
1.62	1.06e-03	GO:0006873	cellular ion homeostasis
1.61	1.16e-03	GO:0055082	cellular chemical homeostasis
1.48	1.17e-03	GO:0006468	protein phosphorylation
2.43	1.37e-03	GO:0010721	negative regulation of cell development
3.13	1.38e-03	GO:0007269	neurotransmitter secretion
1.76	1.93e-03	GO:0051347	positive regulation of transferase activity
2.17	2.09e-03	GO:0007411	axon guidance
2.14	2.44e-03	GO:0030111	regulation of Wnt receptor signaling pathway
2.94	2.75e-03	GO:0022037	metencephalon development
1.28	3.51e-03	GO:0006464	protein modification process
2.09	3.53e-03	GO:0050890	cognition
1.68	3.65e-03	GO:0035295	tube development
1.58	4.10e-03	GO:0060341	regulation of cellular localization
2.12	4.23e-03	GO:0007611	learning or memory
1.07	4.27e-03	GO:0009987	cellular process
1.95	4.76e-03	GO:0016055	Wnt receptor signaling pathway
1.64	5.21e-03	GO:0008610	lipid biosynthetic process
1.51	5.49e-03	GO:0019725	cellular homeostasis
2.36	6.19e-03	GO:0050770	regulation of axonogenesis
1.68	6.33e-03	GO:0045596	negative regulation of cell differentiation
1.60	7.12e-03	GO:0051093	negative regulation of developmental process
1.48	7.20e-03	GO:0046907	intracellular transport
1.78	7.37e-03	GO:0030029	actin filament-based process
2.34	8.22e-03	GO:0001508	regulation of action potential
1.54	8.56e-03	GO:0050801	ion homeostasis
2.69	1.03e-02	GO:0050808	synapse organization
2.01	1.04e-02	GO:0007626	locomotory behavior
1.50	1.08e-02	GO:0051094	positive regulation of developmental process
1.51	1.15e-02	GO:0030001	metal ion transport
2.38	1.16e-02	GO:0030902	hindbrain development
1.47	1.18e-02	GO:0040011	locomotion
2.51	1.19e-02	GO:0045667	regulation of osteoblast differentiation
2.42	1.19e-02	GO:0050768	negative regulation of neurogenesis
2.72	1.37e-02	GO:0007272	ensheathment of neurons
2.72	1.37e-02	GO:0008366	axon ensheathment
1.56	1.40e-02	GO:0016044	cellular membrane organization
1.40	1.42e-02	GO:0044093	positive regulation of molecular function
1.88	1.46e-02	GO:0043062	extracellular structure organization
2.39	1.59e-02	GO:0048167	regulation of synaptic plasticity
2.43	1.62e-02	GO:0019228	regulation of action potential in neuron
2.47	1.63e-02	GO:0021543	pallium development
1.80	1.64e-02	GO:0016337	cell-cell adhesion
1.55	1.75e-02	GO:0061024	membrane organization
1.56	1.94e-02	GO:0044057	regulation of system process
2.17	1.95e-02	GO:0030534	adult behavior
1.56	1.99e-02	GO:0045597	positive regulation of cell differentiation
2.11	2.08e-02	GO:0050769	positive regulation of neurogenesis
2.35	2.13e-02	GO:0001764	neuron migration
2.54	2.18e-02	GO:0070588	calcium ion transmembrane transport
1.46	2.21e-02	GO:0006812	cation transport
3.18	2.62e-02	GO:0010469	regulation of receptor activity
2.70	2.65e-02	GO:0042552	myelination
1.74	2.77e-02	GO:0032940	secretion by cell
1.48	2.89e-02	GO:0048646	anatomical structure formation involved in morphogenesis
2.06	2.95e-02	GO:0006887	exocytosis
1.88	3.03e-02	GO:0060627	regulation of vesicle-mediated transport
1.60	3.19e-02	GO:0051130	positive regulation of cellular component organization
1.25	3.24e-02	GO:0048513	organ development
1.96	3.56e-02	GO:0010720	positive regulation of cell development
2.05	4.05e-02	GO:0032147	activation of protein kinase activity
4.01	4.21e-02	GO:0031114	regulation of microtubule depolymerization
1.42	4.95e-02	GO:0009887	organ morphogenesis

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.27	5.48e-35	GO:0005737	cytoplasm
1.20	5.65e-32	GO:0005622	intracellular
1.19	1.65e-27	GO:0044424	intracellular part
2.25	9.39e-27	GO:0043005	neuron projection
1.85	1.62e-25	GO:0042995	cell projection
2.27	1.46e-23	GO:0045202	synapse
1.10	7.50e-21	GO:0005623	cell
1.10	7.50e-21	GO:0044464	cell part
1.28	1.34e-19	GO:0044444	cytoplasmic part
1.18	5.04e-18	GO:0043226	organelle
1.18	5.29e-18	GO:0043229	intracellular organelle
2.30	7.14e-17	GO:0044456	synapse part
2.42	1.02e-16	GO:0030425	dendrite
2.32	1.07e-16	GO:0043025	neuronal cell body
1.33	1.62e-16	GO:0071944	cell periphery
1.90	6.19e-16	GO:0030054	cell junction
2.25	8.27e-16	GO:0044297	cell body
2.11	1.70e-15	GO:0044463	cell projection part
1.32	2.90e-15	GO:0005886	plasma membrane
1.17	6.69e-14	GO:0016020	membrane
1.64	3.24e-12	GO:0005626	insoluble fraction
1.44	3.93e-12	GO:0044459	plasma membrane part
1.54	2.55e-11	GO:0000267	cell fraction
2.22	2.87e-11	GO:0030424	axon
1.60	3.44e-11	GO:0005794	Golgi apparatus
1.62	5.02e-11	GO:0005624	membrane fraction
1.15	7.82e-11	GO:0043227	membrane-bounded organelle
1.15	1.21e-10	GO:0043231	intracellular membrane-bounded organelle
2.70	1.29e-10	GO:0019717	synaptosome
1.46	2.37e-10	GO:0005856	cytoskeleton
2.44	3.08e-09	GO:0045211	postsynaptic membrane
3.05	6.39e-09	GO:0030427	site of polarized growth
3.08	7.88e-09	GO:0030426	growth cone
2.26	1.22e-07	GO:0031252	cell leading edge
1.50	2.58e-07	GO:0044430	cytoskeletal part
1.88	1.66e-06	GO:0044431	Golgi apparatus part
1.25	5.61e-06	GO:0043234	protein complex
2.69	7.18e-06	GO:0014069	postsynaptic density
2.13	9.71e-06	GO:0030135	coated vesicle
2.24	3.06e-05	GO:0033267	axon part
3.45	4.69e-05	GO:0043198	dendritic shaft
2.11	1.12e-04	GO:0030136	clathrin-coated vesicle
1.86	1.30e-04	GO:0005911	cell-cell junction
1.12	1.43e-04	GO:0044425	membrane part
3.07	1.58e-04	GO:0031256	leading edge membrane
1.79	1.68e-04	GO:0005874	microtubule
1.52	2.48e-04	GO:0015630	microtubule cytoskeleton
2.54	3.52e-04	GO:0005875	microtubule associated complex
2.54	3.52e-04	GO:0044309	neuron spine
1.34	3.75e-04	GO:0031090	organelle membrane
1.43	4.09e-04	GO:0012505	endomembrane system
2.32	4.51e-04	GO:0016327	apicolateral plasma membrane
2.52	6.61e-04	GO:0043197	dendritic spine
2.25	1.01e-03	GO:0008021	synaptic vesicle
1.42	1.08e-03	GO:0031982	vesicle
1.43	1.09e-03	GO:0031410	cytoplasmic vesicle
2.21	1.23e-03	GO:0034703	cation channel complex
2.00	1.81e-03	GO:0070161	anchoring junction
1.28	2.42e-03	GO:0005829	cytosol
1.87	2.47e-03	GO:0034702	ion channel complex
2.23	2.48e-03	GO:0043296	apical junction complex
3.53	2.92e-03	GO:0032589	neuron projection membrane
2.44	3.14e-03	GO:0030662	coated vesicle membrane
1.96	3.29e-03	GO:0031300	intrinsic to organelle membrane
2.95	3.79e-03	GO:0042734	presynaptic membrane
1.66	4.03e-03	GO:0015629	actin cytoskeleton
1.98	6.33e-03	GO:0005912	adherens junction
1.88	6.59e-03	GO:0000139	Golgi membrane
1.20	6.67e-03	GO:0043228	non-membrane-bounded organelle
1.20	6.67e-03	GO:0043232	intracellular non-membrane-bounded organelle
1.15	7.28e-03	GO:0044446	intracellular organelle part
3.17	7.44e-03	GO:0044304	main axon
1.14	7.60e-03	GO:0044422	organelle part
1.16	9.91e-03	GO:0032991	macromolecular complex
2.35	1.43e-02	GO:0008076	voltage-gated potassium channel complex
2.35	1.43e-02	GO:0034705	potassium channel complex
1.84	1.50e-02	GO:0030659	cytoplasmic vesicle membrane
1.58	1.77e-02	GO:0048471	perinuclear region of cytoplasm
2.16	1.89e-02	GO:0030027	lamellipodium
1.29	3.15e-02	GO:0005783	endoplasmic reticulum
2.13	3.31e-02	GO:0005923	tight junction
2.13	3.31e-02	GO:0070160	occluding junction
1.78	3.42e-02	GO:0044433	cytoplasmic vesicle part
2.57	3.76e-02	GO:0005913	cell-cell adherens junction
2.43	3.81e-02	GO:0030665	clathrin coated vesicle membrane
1.74	4.14e-02	GO:0012506	vesicle membrane

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.20	3.03e-31	GO:0005488	binding
1.33	1.17e-29	GO:0005515	protein binding
1.98	1.71e-11	GO:0060589	nucleoside-triphosphatase regulator activity
1.97	5.97e-11	GO:0030695	GTPase regulator activity
1.81	3.50e-10	GO:0008092	cytoskeletal protein binding
1.72	4.41e-08	GO:0019904	protein domain specific binding
2.06	7.74e-08	GO:0005083	small GTPase regulator activity
1.24	3.51e-07	GO:0046872	metal ion binding
1.23	1.00e-06	GO:0043169	cation binding
1.23	1.37e-06	GO:0043167	ion binding
1.51	1.63e-06	GO:0019899	enzyme binding
1.34	2.88e-06	GO:0016740	transferase activity
1.85	3.67e-06	GO:0008047	enzyme activator activity
1.49	4.62e-06	GO:0030234	enzyme regulator activity
1.29	7.16e-06	GO:0000166	nucleotide binding
1.81	1.98e-05	GO:0003779	actin binding
1.44	2.10e-05	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.31	2.94e-05	GO:0032553	ribonucleotide binding
1.47	3.99e-05	GO:0016301	kinase activity
1.30	3.99e-05	GO:0032555	purine ribonucleotide binding
1.31	4.18e-05	GO:0035639	purine ribonucleoside triphosphate binding
1.30	6.17e-05	GO:0017076	purine nucleotide binding
1.51	6.87e-05	GO:0016773	phosphotransferase activity, alcohol group as acceptor
2.24	1.45e-04	GO:0005516	calmodulin binding
2.42	2.59e-04	GO:0030165	PDZ domain binding
1.57	2.74e-04	GO:0008324	cation transmembrane transporter activity
1.53	2.98e-04	GO:0004672	protein kinase activity
1.15	4.42e-04	GO:0003824	catalytic activity
1.88	6.02e-04	GO:0005096	GTPase activator activity
1.46	7.94e-04	GO:0015075	ion transmembrane transporter activity
1.70	2.47e-03	GO:0022836	gated channel activity
1.60	2.74e-03	GO:0005216	ion channel activity
1.72	3.66e-03	GO:0005261	cation channel activity
1.58	3.82e-03	GO:0022838	substrate-specific channel activity
1.39	4.83e-03	GO:0022891	substrate-specific transmembrane transporter activity
1.49	4.90e-03	GO:0005509	calcium ion binding
1.36	6.32e-03	GO:0022892	substrate-specific transporter activity
1.40	7.25e-03	GO:0046983	protein dimerization activity
1.58	8.54e-03	GO:0032403	protein complex binding
1.55	9.19e-03	GO:0022803	passive transmembrane transporter activity
1.53	1.05e-02	GO:0004674	protein serine/threonine kinase activity
4.01	1.09e-02	GO:0042813	Wnt receptor activity
1.53	1.46e-02	GO:0015267	channel activity
2.02	1.60e-02	GO:0003774	motor activity
1.95	1.71e-02	GO:0022843	voltage-gated cation channel activity
1.57	1.95e-02	GO:0005525	GTP binding
1.55	2.03e-02	GO:0019001	guanyl nucleotide binding
1.55	2.03e-02	GO:0032561	guanyl ribonucleotide binding
1.79	2.32e-02	GO:0005244	voltage-gated ion channel activity
1.79	2.32e-02	GO:0022832	voltage-gated channel activity
1.34	2.77e-02	GO:0022857	transmembrane transporter activity
1.30	2.93e-02	GO:0005215	transporter activity
1.25	3.69e-02	GO:0032559	adenyl ribonucleotide binding
2.32	4.76e-02	GO:0019902	phosphatase binding