Motif ID: HLF.p2

Z-value: 1.499


Transcription factors associated with HLF.p2:

Gene SymbolEntrez IDGene Name
Hlf 217082 hepatic leukemia factor

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hlfchr11_-_90250949-0.073.4e-01Click!


Activity profile for motif HLF.p2.

activity profile for motif HLF.p2


Sorted Z-values histogram for motif HLF.p2

Sorted Z-values for motif HLF.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HLF.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_95721654 25.652 Ces1d
carboxylesterase 1D
chr9_-_71011053 23.623 NM_022026
 Aqp9
aquaporin 9
chr3_-_144347983 23.173


chr2_-_129196855 21.323 NM_008361
 Il1b
interleukin 1 beta
chr8_-_95721702 20.324 NM_053200
 Ces1d
carboxylesterase 1D
chr2_+_24200807 20.030 NM_001159562
 Il1rn
interleukin 1 receptor antagonist
chr2_+_24200890 18.772 NM_001039701
 Il1rn
interleukin 1 receptor antagonist
chr10_+_23571267 17.055 NM_011979
 Vnn3
vanin 3
chr7_+_27092187 17.037 NM_009997
 Cyp2a4
cytochrome P450, family 2, subfamily a, polypeptide 4
chr10_+_100055019 16.352 NM_001081246
 1700017N19Rik
RIKEN cDNA 1700017N19 gene
chr10_-_24647173 15.283 Arg1
arginase, liver
chr4_+_43996375 15.256 NM_001002787
 Ccin
calicin
chr18_-_36886051 14.575 Cd14
CD14 antigen
chr7_+_27620380 14.573 Cyp2a4
Cyp2a5
cytochrome P450, family 2, subfamily a, polypeptide 4
cytochrome P450, family 2, subfamily a, polypeptide 5
chr4_+_56756283 13.910 NM_009611
 Actl7a
actin-like 7a
chr11_-_83391984 13.902 Ccl9
chemokine (C-C motif) ligand 9
chr10_-_61970481 13.758 NM_011157
 Srgn
serglycin
chr2_+_24200925 13.268 Il1rn
interleukin 1 receptor antagonist
chr4_-_127938134 12.707 NM_027036
 Hmgb4
high-mobility group box 4
chr7_-_53971038 12.587 NM_011315
 Saa3
serum amyloid A 3

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
3.20 3.58e-02 GO:0006954 inflammatory response
2.58 3.39e-02 GO:0006955 immune response
2.54 4.39e-02 GO:0009611 response to wounding
2.34 3.05e-02 GO:0006952 defense response

Gene overrepresentation in compartment category:

Showing 1 to 4 of 4 entries
Enrichment   P-value GO Accession GO Term
3.85 6.49e-03 GO:0005882 intermediate filament
2.52 3.75e-06 GO:0005615 extracellular space
1.99 1.43e-03 GO:0044421 extracellular region part
1.65 3.21e-03 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
11.80 9.58e-09 GO:0004869 cysteine-type endopeptidase inhibitor activity
7.49 3.61e-02 GO:0008009 chemokine activity
5.53 2.33e-08 GO:0004866 endopeptidase inhibitor activity
5.33 4.85e-08 GO:0061135 endopeptidase regulator activity
5.23 6.91e-08 GO:0030414 peptidase inhibitor activity
4.48 1.33e-06 GO:0061134 peptidase regulator activity
3.95 8.17e-07 GO:0004857 enzyme inhibitor activity