Motif ID: HMX1.p2

Z-value: 1.296


Transcription factors associated with HMX1.p2:

Gene SymbolEntrez IDGene Name
Hmx1 15371 H6 homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmx1chr5_+_35731765-0.223.2e-03Click!


Activity profile for motif HMX1.p2.

activity profile for motif HMX1.p2


Sorted Z-values histogram for motif HMX1.p2

Sorted Z-values for motif HMX1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HMX1.p2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_+_11586215 27.125 NM_001025597
NM_009578
 Ikzf1

IKAROS family zinc finger 1

chr8_+_90796301 18.002 NM_007406
 Adcy7
adenylate cyclase 7
chrX_-_7248403 17.506 NM_019755
 Plp2
proteolipid protein 2
chr11_+_68245608 17.471 NM_177320
 Pik3r5
phosphoinositide-3-kinase, regulatory subunit 5, p101
chr6_-_91066773 14.250 Nup210
nucleoporin 210
chr6_-_91066809 14.149 NM_018815
 Nup210
nucleoporin 210
chr3_-_54538938 13.021 Exosc8
exosome component 8
chr17_+_35331446 12.979 NM_008518
 Ltb
lymphotoxin B
chr17_-_36282006 11.985 H2-D1
histocompatibility 2, D region locus 1
chr11_+_3190334 11.246 NM_019574
 Patz1
POZ (BTB) and AT hook containing zinc finger 1
chr1_+_52065469 11.159 Stat4
signal transducer and activator of transcription 4
chr6_-_124683046 10.917 NM_013545
 Ptpn6
protein tyrosine phosphatase, non-receptor type 6
chr2_+_152934184 10.829 NM_001172117
NM_010407
 Hck

hemopoietic cell kinase

chr15_-_78403110 10.499 NM_009008
 Rac2
RAS-related C3 botulinum substrate 2
chr11_-_117687109 10.306 NM_009387
 Tk1
thymidine kinase 1
chr5_+_123844794 10.097 NM_133917
NM_177582
 Mlxip

MLX interacting protein

chr15_-_102062331 9.934 NM_013566
 Itgb7
integrin beta 7
chr7_-_56136405 9.840 NM_001013368
 E2f8
E2F transcription factor 8
chr7_-_90883999 9.680 NM_010551
 Il16
interleukin 16
chr1_+_52065087 9.499 NM_011487
 Stat4
signal transducer and activator of transcription 4

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 121 entries
Enrichment   P-value GO Accession GO Term
5.48 1.14e-02 GO:0045646 regulation of erythrocyte differentiation
2.47 1.96e-02 GO:0042110 T cell activation
2.46 3.30e-03 GO:0002521 leukocyte differentiation
2.36 4.10e-04 GO:0046649 lymphocyte activation
2.20 6.78e-04 GO:0003002 regionalization
2.16 1.08e-03 GO:0045321 leukocyte activation
2.14 5.32e-04 GO:0030097 hemopoiesis
2.05 1.36e-05 GO:0048598 embryonic morphogenesis
2.04 2.15e-03 GO:0001775 cell activation
1.99 1.58e-02 GO:0048568 embryonic organ development
1.97 3.16e-03 GO:0007420 brain development
1.97 4.41e-03 GO:0048534 hemopoietic or lymphoid organ development
1.94 1.01e-03 GO:0002684 positive regulation of immune system process
1.94 1.01e-03 GO:0045597 positive regulation of cell differentiation
1.94 4.39e-03 GO:0002520 immune system development
1.93 2.84e-03 GO:0007389 pattern specification process
1.87 3.35e-05 GO:0045944 positive regulation of transcription from RNA polymerase II promoter
1.87 1.89e-02 GO:0016071 mRNA metabolic process
1.85 4.90e-08 GO:0010628 positive regulation of gene expression
1.85 3.51e-07 GO:0045893 positive regulation of transcription, DNA-dependent

Gene overrepresentation in compartment category:

Showing 1 to 20 of 27 entries
Enrichment   P-value GO Accession GO Term
1.86 9.94e-03 GO:0005667 transcription factor complex
1.78 9.09e-03 GO:0005730 nucleolus
1.65 6.81e-04 GO:0044451 nucleoplasm part
1.62 2.41e-11 GO:0044428 nuclear part
1.62 4.68e-09 GO:0031981 nuclear lumen
1.62 7.05e-06 GO:0005654 nucleoplasm
1.55 2.46e-08 GO:0070013 intracellular organelle lumen
1.55 2.91e-08 GO:0043233 organelle lumen
1.52 1.03e-07 GO:0031974 membrane-enclosed lumen
1.48 1.67e-25 GO:0005634 nucleus
1.41 1.03e-03 GO:0005829 cytosol
1.31 3.30e-08 GO:0044422 organelle part
1.31 4.93e-08 GO:0044446 intracellular organelle part
1.31 9.47e-04 GO:0043228 non-membrane-bounded organelle
1.31 9.47e-04 GO:0043232 intracellular non-membrane-bounded organelle
1.29 7.81e-05 GO:0032991 macromolecular complex
1.27 4.37e-18 GO:0043227 membrane-bounded organelle
1.27 9.48e-18 GO:0043231 intracellular membrane-bounded organelle
1.27 2.23e-03 GO:0043234 protein complex
1.26 2.03e-20 GO:0043226 organelle

Gene overrepresentation in function category:

Showing 1 to 18 of 18 entries
Enrichment   P-value GO Accession GO Term
2.02 6.13e-03 GO:0019901 protein kinase binding
1.91 1.47e-07 GO:0043565 sequence-specific DNA binding
1.85 2.37e-02 GO:0019900 kinase binding
1.83 7.40e-07 GO:0003723 RNA binding
1.81 6.21e-09 GO:0030528 transcription regulator activity
1.78 1.53e-06 GO:0001071 nucleic acid binding transcription factor activity
1.78 1.53e-06 GO:0003700 sequence-specific DNA binding transcription factor activity
1.71 3.23e-02 GO:0004674 protein serine/threonine kinase activity
1.65 7.80e-03 GO:0004672 protein kinase activity
1.63 1.39e-11 GO:0003677 DNA binding
1.62 7.00e-18 GO:0003676 nucleic acid binding
1.58 9.69e-03 GO:0016773 phosphotransferase activity, alcohol group as acceptor
1.51 1.76e-02 GO:0016301 kinase activity
1.44 4.43e-02 GO:0016772 transferase activity, transferring phosphorus-containing groups
1.38 8.35e-05 GO:0000166 nucleotide binding
1.34 1.05e-02 GO:0016740 transferase activity
1.33 1.19e-13 GO:0005515 protein binding
1.23 5.39e-22 GO:0005488 binding