Motif ID: HOXA9_MEIS1.p2

Z-value: 1.048


Transcription factors associated with HOXA9_MEIS1.p2:

Gene SymbolEntrez IDGene Name
Hoxa9 15405 homeobox A9
Meis1 17268 Meis homeobox 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hoxa9chr6_-_521773680.305.0e-05Click!
Meis1chr11_-_189189230.055.4e-01Click!


Activity profile for motif HOXA9_MEIS1.p2.

activity profile for motif HOXA9_MEIS1.p2


Sorted Z-values histogram for motif HOXA9_MEIS1.p2

Sorted Z-values for motif HOXA9_MEIS1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HOXA9_MEIS1.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr12_-_119474010 21.305 Sp4
trans-acting transcription factor 4
chr13_+_24706474 19.354 NM_178658
Fam65b
family with sequence similarity 65, member B
chr7_+_149657739 19.301 NM_019391
Lsp1
lymphocyte specific 1
chr4_-_46417054 17.103 NM_053149
Hemgn
hemogen
chr11_-_98859189 13.991 Top2a
topoisomerase (DNA) II alpha
chr6_+_113339088 13.908 NM_001142732
Ttll3
Arpc4
tubulin tyrosine ligase-like family, member 3
actin related protein 2/3 complex, subunit 4
chr1_+_175603760 12.721 NM_001162938
Pydc3
pyrin domain containing 3
chr17_-_71824652 11.741 NM_028887
Smchd1
SMC hinge domain containing 1
chr9_-_44611055 11.532 Ttc36
tetratricopeptide repeat domain 36
chr4_-_46416895 9.552 Hemgn
hemogen
chr16_+_37580238 9.209 NM_013547
Hgd
homogentisate 1, 2-dioxygenase
chr17_-_37712365 8.916 NM_146289
Olfr113
olfactory receptor 113
chr9_-_44610921 8.841 Ttc36
tetratricopeptide repeat domain 36
chr11_-_94154354 8.825 Luc7l3
LUC7-like 3 (S. cerevisiae)
chr19_-_7877136 8.809 NM_146232
BC014805
cDNA sequence BC014805
chr9_-_44611033 8.722 NM_138951
Ttc36
tetratricopeptide repeat domain 36
chr19_-_7877065 8.262 BC014805
cDNA sequence BC014805
chr15_-_96245209 8.111 Scaf11
SR-related CTD-associated factor 11
chr1_-_175157322 8.004 NM_010184
Fcer1a
Fc receptor, IgE, high affinity I, alpha polypeptide
chr5_+_136533136 7.222 NM_027158
2310043J07Rik
RIKEN cDNA 2310043J07 gene
chr16_-_46120221 7.104 NM_032465
Cd96
CD96 antigen
chr3_+_27215949 7.063 NM_009425
Tnfsf10
tumor necrosis factor (ligand) superfamily, member 10
chr1_+_60803231 6.587 NM_007642
Cd28
CD28 antigen
chr10_-_126788827 6.333 NM_008382
Inhbe
inhibin beta E
chrY_-_582062 6.234 NM_009484
Uty
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr5_-_139060952 5.402 NM_001044747
NM_001163797
NM_013844
Zfp68


zinc finger protein 68


chr4_-_151412494 5.389 NM_031867
Tas1r1
taste receptor, type 1, member 1
chr11_-_11790403 5.286 NM_016672
Ddc
dopa decarboxylase
chr1_-_175529396 5.212 NM_001177349
NM_001177350
Pydc4

pyrin domain containing 4

chr17_-_37727295 5.187 NM_146287
Olfr114
olfactory receptor 114
chr2_+_40412520 5.100 Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr19_+_25127069 5.087 Dock8
dedicator of cytokinesis 8
chr16_-_26526854 5.010 NM_001101640
Tmem207
transmembrane protein 207
chr11_+_53138176 4.868 NM_026479
Zcchc10
zinc finger, CCHC domain containing 10
chr6_+_73226746 4.525 Suclg1
succinate-CoA ligase, GDP-forming, alpha subunit
chr17_-_65989095 4.517 NM_153519
Txndc2
thioredoxin domain containing 2 (spermatozoa)
chr9_-_22064292 4.458 NM_181419
Zfp599
zinc finger protein 599
chrX_-_71598873 4.397 NM_025410
Lage3
L antigen family, member 3
chr3_+_89862664 4.384 4933434E20Rik
RIKEN cDNA 4933434E20 gene
chr8_-_41393270 4.359 1500004F05Rik
RIKEN cDNA 1500004F05 gene
chr6_+_50150160 4.258 Mpp6
membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6)
chr5_+_140019846 4.196 NM_013702
Uncx
UNC homeobox
chr1_+_177562307 4.188 Kmo
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr2_+_24041995 3.983 NM_153511
Il1f9
interleukin 1 family, member 9
chr2_+_156698083 3.925 1110008F13Rik
RIKEN cDNA 1110008F13 gene
chr1_-_109174947 3.919 NM_201363
Serpinb3c
serine (or cysteine) peptidase inhibitor, clade B, member 3C
chr6_+_41634429 3.908 NM_029671
1700034O15Rik
RIKEN cDNA 1700034O15 gene
chr5_-_114280434 3.848 NM_009151
Selplg
selectin, platelet (p-selectin) ligand
chr16_-_75909440 3.802 NM_023380
Samsn1
SAM domain, SH3 domain and nuclear localization signals, 1
chr10_+_117878101 3.775 NM_008337
Ifng
interferon gamma
chr1_-_140071630 3.629 Ptprc
protein tyrosine phosphatase, receptor type, C
chr7_-_53927906 3.341 NM_009414
Tph1
tryptophan hydroxylase 1
chr11_-_106062079 3.287 Ccdc47
coiled-coil domain containing 47
chr1_-_197002841 3.264 NM_007758
Cr2
complement receptor 2
chr10_-_61970481 3.130 NM_011157
Srgn
serglycin
chr5_-_101249953 3.112 NM_172405
Fam175a
family with sequence similarity 175, member A
chr2_-_87875293 3.069 NM_054090
Olfr73
olfactory receptor 73
chr2_+_150396150 3.060 NM_009977
Cst7
cystatin F (leukocystatin)
chr9_-_78326584 3.027 Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr9_+_7792286 3.007 Tmem123
transmembrane protein 123
chr11_-_75114563 3.000 Rpa1
replication protein A1
chr2_-_34817068 2.961 NM_009421
Traf1
TNF receptor-associated factor 1
chr9_-_78326621 2.910 Eef1a1
eukaryotic translation elongation factor 1 alpha 1
chr14_-_64147067 2.766 Mtmr9
myotubularin related protein 9
chr12_+_33535650 2.731 Nampt
nicotinamide phosphoribosyltransferase
chr13_+_3837002 2.683 NM_020036
Calm4
calmodulin 4
chr3_+_84470230 2.678 Tmem154
transmembrane protein 154
chr13_+_3837037 2.668 Calm4
calmodulin 4
chr3_-_90195440 2.618


chr8_+_41837561 2.614 NM_011781
Adam25
a disintegrin and metallopeptidase domain 25 (testase 2)
chr17_-_37747723 2.612 NM_001011753
Olfr115
olfactory receptor 115
chr5_+_65739560 2.590 NM_031180
Klb
klotho beta
chr7_+_109850836 2.575 NM_147093
Olfr558
olfactory receptor 558
chr16_+_20097626 2.570 NM_029436
Klhl24
kelch-like 24 (Drosophila)
chr1_-_84741605 2.569 Trip12
thyroid hormone receptor interactor 12
chr14_+_52913867 2.534 Tox4
TOX high mobility group box family member 4
chr4_+_140723459 2.513 Fbxo42
F-box protein 42
chr1_-_166865638 2.493 NM_008510
Xcl1
chemokine (C motif) ligand 1
chr5_+_114454810 2.475 Dao
D-amino acid oxidase
chr11_+_121462932 2.395 Tbcd
tubulin-specific chaperone d
chr10_+_127452270 2.347 NM_008921
Prim1
DNA primase, p49 subunit
chr15_-_9459612 2.325 NM_008372
Il7r
interleukin 7 receptor
chr7_+_104629465 2.322 NM_027256
Ints4
integrator complex subunit 4
chr14_+_41918624 2.317 NM_133653
Mat1a
methionine adenosyltransferase I, alpha
chr1_+_175350728 2.297 NM_001013779
Aim2
absent in melanoma 2
chr6_-_127076410 2.296 Ccnd2
cyclin D2
chr1_+_177562321 2.292 NM_133809
Kmo
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr17_+_25445590 2.261 NM_053259
Prss28
protease, serine, 28
chr18_+_37467108 2.186 NM_053129
Pcdhb4
protocadherin beta 4
chr1_-_173165051 2.172


chr15_-_101648565 2.163 NM_010668
Krt2
keratin 2
chr4_+_122731563 2.105 Trit1
tRNA isopentenyltransferase 1
chr15_-_98373055 2.095 Ccnt1
cyclin T1
chr11_-_40562196 2.089


chr9_+_110782677 2.052 NM_001146059
NM_146228
NM_001146060
Als2cl


ALS2 C-terminal like


chr11_+_33947115 2.033 NM_010696
Lcp2
lymphocyte cytosolic protein 2
chr9_+_19426528 2.014 NM_172918
Zfp317
zinc finger protein 317
chr18_+_35776026 2.001 Paip2
polyadenylate-binding protein-interacting protein 2
chr4_+_150371205 1.980 NM_011910
Uts2
urotensin 2
chr19_+_8994949 1.966 B3gat3
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr16_-_36367622 1.954 NM_001082546
BC100530
BC117090
cDNA sequence BC100530
cDNA sequence BC1179090
chr9_+_64083007 1.934 NM_033607
Uchl4
ubiquitin carboxyl-terminal esterase L4
chr9_-_44550590 1.927


chr6_-_106698941 1.910 NM_008370
Il5ra
interleukin 5 receptor, alpha
chr4_+_126800830 1.894 Zmym6
zinc finger, MYM-type 6
chr5_-_66472208 1.889 Rbm47
RNA binding motif protein 47
chr6_+_116600624 1.872 NM_001166580
NM_145980
8430408G22Rik

RIKEN cDNA 8430408G22 gene

chr16_-_55934909 1.857 NM_001159364
NM_001159365
NM_001159366
NM_028815
Cep97



centrosomal protein 97



chr3_-_92524255 1.833 NM_026394
Lce1f
late cornified envelope 1F
chr16_-_88627910 1.830 NM_027173
2310079G19Rik
RIKEN cDNA 2310079G19 gene
chrX_+_109424956 1.818 NM_026565
Apool
apolipoprotein O-like
chr18_-_78320014 1.810 Slc14a1
solute carrier family 14 (urea transporter), member 1
chr3_+_89006938 1.783 Gba
glucosidase, beta, acid
chr9_+_108294086 1.741 Usp4
ubiquitin specific peptidase 4 (proto-oncogene)
chr14_-_73948048 1.737 NM_172527
Nudt15
nudix (nucleoside diphosphate linked moiety X)-type motif 15
chr4_+_155387803 1.696 NM_011659
Tnfrsf4
tumor necrosis factor receptor superfamily, member 4
chr17_-_26063534 1.690


chr4_+_154335029 1.671 NM_010419
Hes5
hairy and enhancer of split 5 (Drosophila)
chr16_+_26463220 1.626 NM_053241
Cldn16
claudin 16
chr8_+_74676812 1.613


chr15_-_81238649 1.565 NM_021317
Dnajb7
DnaJ (Hsp40) homolog, subfamily B, member 7
chrX_+_90900201 1.542 NM_177546
Pcyt1b
phosphate cytidylyltransferase 1, choline, beta isoform
chr5_-_139060905 1.518 Zfp68
zinc finger protein 68
chr1_-_168058009 1.502 NM_001033344
NM_001160049
Dusp27

dual specificity phosphatase 27 (putative)

chr19_+_3958805 1.497 1700055N04Rik
RIKEN cDNA 1700055N04 gene
chr3_+_89006824 1.491 NM_001077411
NM_008094
Gba

glucosidase, beta, acid

chr2_-_34708015 1.488 Psmd5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 5
chr3_+_129539656 1.478 NM_007686
Cfi
complement component factor i
chr9_+_107199169 1.474 Cish
cytokine inducible SH2-containing protein
chr17_-_79306331 1.465 NM_001163625
Sult6b1
sulfotransferase family, cytosolic, 6B, member 1
chr8_+_107370966 1.464 NM_145603
Ces2c
carboxylesterase 2C
chr9_+_51855254 1.457 NM_001104616
Rdx
radixin
chr6_-_127075853 1.412 Ccnd2
cyclin D2
chr6_+_17616617 1.379 Capza2
capping protein (actin filament) muscle Z-line, alpha 2
chrX_+_137491455 1.356 NM_174875
Atg4a
autophagy-related 4A (yeast)
chr12_+_53955707 1.337 Akap6
A kinase (PRKA) anchor protein 6
chr4_+_135354137 1.329 Myom3
myomesin family, member 3
chr11_-_11798101 1.325 Ddc
dopa decarboxylase
chr12_+_112404645 1.317 NM_001048206
NM_011632
Traf3

TNF receptor-associated factor 3

chr2_+_4897196 1.316 Ucma
upper zone of growth plate and cartilage matrix associated
chr16_+_36156891 1.306 NM_173869
Stfa2l1
stefin A2 like 1
chr16_+_37580303 1.298 Hgd
homogentisate 1, 2-dioxygenase
chr11_-_99212407 1.279 NM_010666
Krt27
keratin 27
chr3_+_51299646 1.257


chr7_+_97574821 1.251 NM_027298
Ccdc89
coiled-coil domain containing 89
chr16_+_65520846 1.248 NM_008849
Pou1f1
POU domain, class 1, transcription factor 1
chr2_+_172294281 1.233 2410001C21Rik
RIKEN cDNA 2410001C21 gene
chr7_-_106987766 1.223 Spcs2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr19_+_6080032 1.222 NM_001111317
BC048609
cDNA sequence BC048609
chr17_+_25455598 1.215 NM_053260
Prss29
protease, serine, 29
chr19_-_8479532 1.213 NM_177002
C730048C13Rik
RIKEN cDNA C730048C13 gene
chr9_-_39066263 1.195 NM_146506
Olfr945
olfactory receptor 945
chr2_+_11627013 1.132 NM_133836
Il15ra
interleukin 15 receptor, alpha chain
chr5_+_118619772 1.130 NM_007545
Hrk
harakiri, BCL2 interacting protein (contains only BH3 domain)
chr19_-_8206403 1.124 NM_001013820
Gm5631
predicted gene 5631
chr4_+_132091462 1.115 NM_172400
Dnajc8
DnaJ (Hsp40) homolog, subfamily C, member 8
chr11_+_96668506 1.095 Cbx1
chromobox homolog 1 (Drosophila HP1 beta)
chr6_-_117887352 1.060 NM_001173372
NM_033648
Fxyd4

FXYD domain-containing ion transport regulator 4

chr9_-_104239997 1.059 NM_019807
NM_207668
Acpp

acid phosphatase, prostate

chr1_-_109057687 1.057 NM_198680
Serpinb3b
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B
chr2_+_122573644 1.025


chr7_+_128089656 0.994 Polr3e
polymerase (RNA) III (DNA directed) polypeptide E
chr2_+_85791221 0.969 NM_001011774
Olfr1028
olfactory receptor 1028
chr5_+_88916999 0.954 NM_017468
Enam
enamelin
chr1_+_132628552 0.944 NM_177604
AA986860
expressed sequence AA986860
chr4_-_46579311 0.944 NM_178893
Coro2a
coronin, actin binding protein 2A
chr11_-_96168185 0.925 0610040B09Rik
RIKEN cDNA 0610040B09 gene
chr6_-_149049906 0.910 Dennd5b
DENN/MADD domain containing 5B
chr8_+_34842304 0.901 NM_001167921
Gtf2e2
general transcription factor II E, polypeptide 2 (beta subunit)
chr11_-_40562329 0.895


chr11_+_85646309 0.887 Tbx2
T-box 2
chr10_-_106922986 0.879 NM_008656
Myf5
myogenic factor 5
chr6_-_118361541 0.875 Bms1
BMS1 homolog, ribosome assembly protein (yeast)
chr14_+_80400057 0.874 NM_001030294
Olfm4
olfactomedin 4
chr5_+_150821249 0.862 NM_080468
Rxfp2
relaxin/insulin-like family peptide receptor 2
chr7_-_116875215 0.850 NM_020051
Ascl3
achaete-scute complex homolog 3 (Drosophila)
chr18_+_37170365 0.806 NM_009960
Pcdha11
protocadherin alpha 11
chr13_-_97804287 0.751 NM_001080777
NM_025585
1700029F12Rik

RIKEN cDNA 1700029F12 gene

chr5_-_72895711 0.738 NM_001122756
Corin
corin
chr9_-_61761227 0.724 Rplp1
ribosomal protein, large, P1
chr6_+_121586190 0.712 NM_175628
A2m
alpha-2-macroglobulin
chr13_+_68736315 0.706 NM_027035
1700001L19Rik
RIKEN cDNA 1700001L19 gene
chr8_+_107355500 0.685 NM_198171
Ces2b
carboxyesterase 2B
chr10_-_13108775 0.676 NM_001195066
Phactr2
phosphatase and actin regulator 2
chr10_-_21787884 0.660 NM_053264
4930444G20Rik
RIKEN cDNA 4930444G20 gene
chr4_+_132091510 0.647 Dnajc8
DnaJ (Hsp40) homolog, subfamily C, member 8
chr15_-_74942109 0.632 NM_001099217
Ly6c2
lymphocyte antigen 6 complex, locus C2
chr16_-_89571427 0.624 NM_001113406
Krtap11-1
keratin associated protein 11-1
chr4_-_43849385 0.622 NM_019475
Olfr157
olfactory receptor 157
chr2_+_78710638 0.606 Ube2e3
ubiquitin-conjugating enzyme E2E 3, UBC4/5 homolog (yeast)
chr2_-_85504611 0.603 NM_013728
Olfr154
olfactory receptor 154
chr5_+_3571565 0.597 NM_029843
1700109H08Rik
RIKEN cDNA 1700109H08 gene
chr14_+_103446193 0.583 Irg1
immunoresponsive gene 1
chr17_-_53985142 0.575 NM_026935
Sult1c2
sulfotransferase family, cytosolic, 1C, member 2
chr9_-_107888185 0.562 6230427J02Rik
RIKEN cDNA 6230427J02 gene
chrX_-_16488889 0.530 NM_010883
Ndp
Norrie disease (pseudoglioma) (human)
chr11_-_70783381 0.522 Nup88
nucleoporin 88
chr14_+_31832323 0.516 NM_001081251
Pbrm1
polybromo 1
chr9_+_54828686 0.492 NM_176844
Chrna5
cholinergic receptor, nicotinic, alpha polypeptide 5
chr5_+_77269623 0.482 NM_001163793
C530008M17Rik
RIKEN cDNA C530008M17 gene

Gene Ontology Analysis

Nothing significant found in process category.

Nothing significant found in compartment category.

Nothing significant found in function category.