Motif ID: HSF1,2.p2

Z-value: 2.313


Transcription factors associated with HSF1,2.p2:

Gene SymbolEntrez IDGene Name
Hsf1 15499 heat shock factor 1
Hsf2 15500 heat shock factor 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hsf2chr10_+_57206184-0.063.9e-01Click!
Hsf1chr15_+_76307820-0.037.3e-01Click!


Activity profile for motif HSF1,2.p2.

activity profile for motif HSF1,2.p2


Sorted Z-values histogram for motif HSF1,2.p2

Sorted Z-values for motif HSF1,2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of HSF1,2.p2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr5_+_136363914 72.362 Hspb1
heat shock protein 1
chr11_-_55208276 50.467


chrX_+_54032914 43.227 Fhl1
four and a half LIM domains 1
chr1_-_172018982 41.571 NM_022563
Ddr2
discoidin domain receptor family, member 2
chrX_+_54032858 40.579 NM_001077362
Fhl1
four and a half LIM domains 1
chr1_-_66981900 40.150 NM_001113387
Myl1
myosin, light polypeptide 1
chr5_+_136363810 38.667 Hspb1
heat shock protein 1
chr14_-_46149660 38.317 NM_146054
Fermt2
fermitin family homolog 2 (Drosophila)
chr7_-_74879894 35.907 Synm
synemin, intermediate filament protein
chr4_+_41774206 34.150 NM_011335
NM_001193668
NM_001193666
NM_023052
Ccl21b
Gm10591
Gm13304
Ccl21a
Ccl21c
chemokine (C-C motif) ligand 21B (leucine)
predicted gene 10591
predicted gene 13304
chemokine (C-C motif) ligand 21A (serine)
chemokine (C-C motif) ligand 21C (leucine)
chr5_+_136363769 33.460 NM_013560
Hspb1
heat shock protein 1
chr1_+_166726827 31.212 NM_019759
Dpt
dermatopontin
chr7_+_147949708 31.165 NM_021282
Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
chr7_+_147949637 30.387 Cyp2e1
cytochrome P450, family 2, subfamily e, polypeptide 1
chr4_-_82151004 29.701 Nfib
nuclear factor I/B
chr1_-_45559904 28.665 Col5a2
collagen, type V, alpha 2
chr15_-_76881097 27.973 NM_013593
Mb
myoglobin
chr5_+_17080553 27.678 NM_013657
Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr1_-_45559866 27.554 Col5a2
collagen, type V, alpha 2
chr5_-_116872852 27.256 NM_030704
Hspb8
heat shock protein 8
chr4_-_42393043 27.097 NM_011335
NM_001193668
NM_001193666
NM_023052
Ccl21b
Gm10591
Gm13304
Ccl21a
Ccl21c
chemokine (C-C motif) ligand 21B (leucine)
predicted gene 10591
predicted gene 13304
chemokine (C-C motif) ligand 21A (serine)
chemokine (C-C motif) ligand 21C (leucine)
chr4_+_42231042 26.984 NM_001193667
NM_011124
Gm1987
Ccl21a
predicted gene 1987
chemokine (C-C motif) ligand 21A (serine)
chr4_-_42787449 26.961 NM_001193667
NM_011124
Gm1987
Ccl21a
predicted gene 1987
chemokine (C-C motif) ligand 21A (serine)
chr4_-_82151590 25.233 Nfib
nuclear factor I/B
chr16_+_45093784 25.186 Ccdc80
coiled-coil domain containing 80
chr7_-_31861665 24.683 NM_008557
Fxyd3
FXYD domain-containing ion transport regulator 3
chr3_+_67696141 23.971 NM_001113419
NM_177585
Iqcj-schip1
Iqcj
IQ motif containing J-schwannomin interacting protein 1 read-through transcript
IQ motif containing J
chr14_+_102239673 22.702 Lmo7
LIM domain only 7
chr2_-_125142715 22.377 Fbn1
fibrillin 1
chr7_-_106501642 21.589 NM_001111043
NM_001111044
NM_009825
Serpinh1


serine (or cysteine) peptidase inhibitor, clade H, member 1


chr7_-_106501620 21.224 Serpinh1
serine (or cysteine) peptidase inhibitor, clade H, member 1
chr1_-_82232392 21.056 Irs1
insulin receptor substrate 1
chr9_-_66881744 20.822 Tpm1
tropomyosin 1, alpha
chr3_-_10208575 20.553 NM_024406
Fabp4
fatty acid binding protein 4, adipocyte
chr7_-_106501584 20.284 Serpinh1
serine (or cysteine) peptidase inhibitor, clade H, member 1
chr8_+_95376459 19.999 Mmp2
matrix metallopeptidase 2
chr9_+_50561092 19.678 Cryab
crystallin, alpha B
chr11_+_66984528 19.275 NM_001039545
Myh2
myosin, heavy polypeptide 2, skeletal muscle, adult
chr6_+_17290478 18.884 Cav1
caveolin 1, caveolae protein
chr14_+_20570444 18.637 NM_008695
Nid2
nidogen 2
chr17_-_35096167 18.488 NM_010478
Hspa1b
Hspa1a
heat shock protein 1B
heat shock protein 1A
chr1_-_79855177 18.391 Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr3_-_126646303 18.174 NM_001034168
Ank2
ankyrin 2, brain
chr5_+_92760866 17.535 NM_181728
Art3
ADP-ribosyltransferase 3
chr12_+_76409299 17.377 NM_023275
Rhoj
ras homolog gene family, member J
chr4_-_82151657 17.339 Nfib
nuclear factor I/B
chr10_-_27336648 17.270 NM_008481
Lama2
laminin, alpha 2
chr1_+_43787442 16.890 NM_024283
1500015O10Rik
RIKEN cDNA 1500015O10 gene
chr16_-_45844409 16.738 NM_153412
Phldb2
pleckstrin homology-like domain, family B, member 2
chr18_-_43552694 16.283 NM_009468
Dpysl3
dihydropyrimidinase-like 3
chr14_+_51710846 16.224 Rnase4
ribonuclease, RNase A family 4
chr18_-_35881144 16.085 NM_001033141
Ecscr
endothelial cell-specific chemotaxis regulator
chr7_-_149762551 16.035 H19
H19 fetal liver mRNA
chr9_+_50561121 15.400 Cryab
crystallin, alpha B
chr1_+_43787537 15.385 1500015O10Rik
RIKEN cDNA 1500015O10 gene
chr12_+_110782654 15.263 Meg3
maternally expressed 3
chr9_+_50561315 15.245 Cryab
crystallin, alpha B
chr7_+_135667279 14.805 Bag3
BCL2-associated athanogene 3
chr15_+_78673024 14.772 NM_027219
Cdc42ep1
CDC42 effector protein (Rho GTPase binding) 1
chr3_+_137004041 14.700 NM_001163522
NM_016885
Emcn

endomucin

chr1_+_43787692 14.662 1500015O10Rik
RIKEN cDNA 1500015O10 gene
chr9_+_54547344 14.529 NM_021422
Dnaja4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr6_+_4471231 14.467 Col1a2
collagen, type I, alpha 2
chr9_-_54407955 14.415 Cib2
calcium and integrin binding family member 2
chr11_-_11832366 14.415 Grb10
growth factor receptor bound protein 10
chr16_+_48842663 14.390 NM_020509
Retnla
resistin like alpha
chr6_-_136824217 14.279 Mgp
matrix Gla protein
chr18_+_20823750 14.176 NM_013697
Ttr
transthyretin
chr6_-_21802514 14.122 NM_173007
Tspan12
tetraspanin 12
chr12_+_110783593 14.107 Meg3
maternally expressed 3
chr11_+_53915017 14.001 P4ha2
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide
chr3_+_137004089 13.838 Emcn
endomucin
chr16_+_45093816 13.580 Ccdc80
coiled-coil domain containing 80
chr7_-_133606617 13.487 Atp2a1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chr5_+_32913539 13.438 NM_009535
Yes1
Yamaguchi sarcoma viral (v-yes) oncogene homolog 1
chr16_-_45844343 13.381 Phldb2
pleckstrin homology-like domain, family B, member 2
chr2_+_157385835 13.359 NM_010923
NM_180960
Nnat

neuronatin

chr1_+_137648101 13.353 Csrp1
cysteine and glycine-rich protein 1
chr6_+_34548512 13.241 Cald1
caldesmon 1
chr9_+_50561381 13.155 Cryab
crystallin, alpha B
chr6_+_56828743 13.102 Fkbp9
FK506 binding protein 9
chr7_-_112630662 12.980 NM_028444
Prkcdbp
protein kinase C, delta binding protein
chr5_+_93032108 12.916 Stbd1
starch binding domain 1
chr18_+_20823908 12.912 Ttr
transthyretin
chr9_+_54547190 12.869 Dnaja4
DnaJ (Hsp40) homolog, subfamily A, member 4
chr7_+_119822831 12.773 NM_001166584
NM_009346
Tead1

TEA domain family member 1

chr7_+_135390325 12.622 NM_009365
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chr1_-_45560001 12.550 NM_007737
Col5a2
collagen, type V, alpha 2
chr1_-_79855209 12.502 Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr10_+_18246228 12.392 Nhsl1
NHS-like 1
chr15_+_97962651 12.384


chr11_-_69761489 12.372 NM_009204
Slc2a4
solute carrier family 2 (facilitated glucose transporter), member 4
chr5_+_93032061 12.326 NM_175096
Stbd1
starch binding domain 1
chr2_+_20431673 12.190 NM_029895
NM_178059
Etl4

enhancer trap locus 4

chr2_+_122607734 12.095 NM_021507
Sqrdl
sulfide quinone reductase-like (yeast)
chr7_-_133606586 11.785 NM_007504
Atp2a1
ATPase, Ca++ transporting, cardiac muscle, fast twitch 1
chrX_-_73088288 11.714 NM_001166454
Pls3
plastin 3 (T-isoform)
chr4_+_42625654 11.680 NM_011335
NM_001193668
NM_001193666
NM_023052
Ccl21b
Gm10591
Gm13304
Ccl21a
Ccl21c
chemokine (C-C motif) ligand 21B (leucine)
predicted gene 10591
predicted gene 13304
chemokine (C-C motif) ligand 21A (serine)
chemokine (C-C motif) ligand 21C (leucine)
chr4_-_82150687 11.675 Nfib
nuclear factor I/B
chr6_-_142456402 11.573 NM_008492
Ldhb
lactate dehydrogenase B
chr19_+_20676453 11.451 NM_013467
Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr7_+_119902897 11.434 NM_001166585
Tead1
TEA domain family member 1
chr17_-_56419161 11.356 Plin3
perilipin 3
chr10_+_79174315 11.334 Bsg
basigin
chr13_-_93564652 11.262 NM_011582
Thbs4
thrombospondin 4
chr19_+_38598686 11.243 NM_019588
Plce1
phospholipase C, epsilon 1
chr18_+_37896589 11.120 NM_033592
Pcdhga9
protocadherin gamma subfamily A, 9
chr17_+_44325518 11.087 NM_172621
Clic5
chloride intracellular channel 5
chr3_+_95965959 11.076 Mtmr11
myotubularin related protein 11
chr1_-_72921438 11.050 NM_010518
Igfbp5
insulin-like growth factor binding protein 5
chr1_+_159436875 10.990 NM_033354
Sec16b
SEC16 homolog B (S. cerevisiae)
chr10_+_79353650 10.961 Cfd
complement factor D (adipsin)
chr6_+_30589440 10.918 Cpa1
carboxypeptidase A1
chr5_-_44485951 10.750 NM_001163578
NM_001163581
NM_001163582
NM_001163583
NM_001163584
NM_001163585
Prom1





prominin 1





chr2_+_35111861 10.737 Gsn
gelsolin
chr2_-_84614960 10.696 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr6_-_142519807 10.685 NM_008428
Kcnj8
potassium inwardly-rectifying channel, subfamily J, member 8
chr9_+_50560862 10.672 NM_009964
Cryab
crystallin, alpha B
chr18_+_32091098 10.645 NM_144862
Lims2
LIM and senescent cell antigen like domains 2
chr16_+_30065419 10.624 NM_008235
Hes1
hairy and enhancer of split 1 (Drosophila)
chr10_+_79174337 10.558 Bsg
basigin
chrX_+_10173557 10.509


chr11_+_78002569 10.475 Rab34
RAB34, member of RAS oncogene family
chr4_+_150229178 10.456 NM_133753
Errfi1
ERBB receptor feedback inhibitor 1
chr14_+_51710751 10.437 NM_001161731
NM_021472
Ang
Rnase4
angiogenin, ribonuclease, RNase A family, 5
ribonuclease, RNase A family 4
chr1_+_94728419 10.365 Gpc1
glypican 1
chr5_-_150438704 10.290 Hsph1
heat shock 105kDa/110kDa protein 1
chr1_-_72921098 10.239 Igfbp5
insulin-like growth factor binding protein 5
chr7_-_86887849 10.184 NM_011068
Pex11a
peroxisomal biogenesis factor 11 alpha
chr4_-_58083082 10.076 Svep1
sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1
chr2_+_152561983 10.072 NM_010495
Id1
inhibitor of DNA binding 1
chr5_-_150438750 10.070 Hsph1
heat shock 105kDa/110kDa protein 1
chr18_-_14002490 10.068 Zfp521
zinc finger protein 521
chr6_-_21802087 9.938 Tspan12
tetraspanin 12
chr18_+_23573939 9.929 Dtna
dystrobrevin alpha
chr7_-_109082300 9.812 NM_001162973
NM_027053
Lrrc51

leucine rich repeat containing 51

chr7_-_4704436 9.777 NM_183406
NM_183405
Cox6b2

cytochrome c oxidase subunit VIb polypeptide 2

chr2_-_84614976 9.697 Serping1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr11_+_28767772 9.612 Efemp1
epidermal growth factor-containing fibulin-like extracellular matrix protein 1
chr7_+_134355216 9.526 Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr4_+_133871031 9.439 NM_001039048
Trim63
tripartite motif-containing 63
chr15_-_96886327 9.390 NM_027052
Slc38a4
solute carrier family 38, member 4
chr1_-_72920776 9.367 Igfbp5
insulin-like growth factor binding protein 5
chr8_-_47292973 9.358 Slc25a4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr3_+_95965892 9.351 NM_181409
Mtmr11
myotubularin related protein 11
chr11_+_98245124 9.320 NM_011540
Tcap
titin-cap
chr11_+_96711152 9.294 NM_019877
Copz2
coatomer protein complex, subunit zeta 2
chr9_-_54407862 9.245 NM_019686
Cib2
calcium and integrin binding family member 2
chrX_+_93650774 9.161 NM_001159628
NM_010417
Heph

hephaestin

chr7_+_135689619 9.134 Bag3
BCL2-associated athanogene 3
chr9_-_101101334 9.056 NM_172144
Ppp2r3a
protein phosphatase 2, regulatory subunit B'', alpha
chr9_-_15105965 9.041 NM_133732
4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr12_+_32008372 9.039 Lamb1
laminin B1
chr10_-_75106702 8.977 NM_001162913
NM_027890
Susd2

sushi domain containing 2

chr2_+_172978566 8.851 NM_011044
Pck1
phosphoenolpyruvate carboxykinase 1, cytosolic
chr17_+_44325664 8.847 Clic5
chloride intracellular channel 5
chr14_+_69984344 8.831 Entpd4
ectonucleoside triphosphate diphosphohydrolase 4
chr4_-_43536296 8.824 Tpm2
tropomyosin 2, beta
chr2_+_164388211 8.790 NM_026323
Wfdc2
WAP four-disulfide core domain 2
chrX_+_132528317 8.775 NM_029823
6530401D17Rik
2900062L11Rik
RIKEN cDNA 6530401D17 gene
RIKEN cDNA 2900062L11 gene
chr10_-_78054639 8.698 NM_027875
Syde1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr3_+_90346956 8.674 S100a16
S100 calcium binding protein A16
chr1_+_34347244 8.544 Dst
dystonin
chr6_+_81991613 8.538 NM_145570
Fam176a
family with sequence similarity 176, member A
chr18_+_23573908 8.496 NM_010087
NM_207650
Dtna

dystrobrevin alpha

chr19_-_20802015 8.451 NM_011921
Aldh1a7
aldehyde dehydrogenase family 1, subfamily A7
chr15_+_100165359 8.433 NM_001081471
Gm10035
predicted gene 10035
chr14_-_122196929 8.388 NM_134074
Dock9
dedicator of cytokinesis 9
chr16_+_48872720 8.382 NM_181596
Retnlg
resistin like gamma
chr18_+_23573977 8.377 Dtna
dystrobrevin alpha
chr1_-_174221511 8.329 Atp1a2
ATPase, Na+/K+ transporting, alpha 2 polypeptide
chr4_+_135700717 8.308 Id3
inhibitor of DNA binding 3
chr7_-_77511607 8.279 NM_183261
Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr9_-_30957394 8.277


chr17_+_34807445 8.240 NM_031176
Tnxb
tenascin XB
chr7_+_99710002 8.210 Ccdc90b
coiled-coil domain containing 90B
chr8_+_47576483 8.196 Acsl1
acyl-CoA synthetase long-chain family member 1
chr4_-_82151180 8.096 NM_001113209
NM_001113210
NM_008687
Nfib


nuclear factor I/B


chr7_+_135667095 8.024 NM_013863
Bag3
BCL2-associated athanogene 3
chr18_-_53577625 7.997 NM_008908
Ppic
peptidylprolyl isomerase C
chrM_+_12383 7.965


chr9_+_14080805 7.916 Sesn3
sestrin 3
chr9_+_14080744 7.888 NM_030261
Sesn3
sestrin 3
chr2_+_174123359 7.874 NM_001077507
NM_010309
NM_201617
NM_201618
Gnas



GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus



chr9_-_15105864 7.843 4931406C07Rik
RIKEN cDNA 4931406C07 gene
chr11_+_100277007 7.826 NM_001163481
NM_010221
Fkbp10

FK506 binding protein 10

chr19_+_58744854 7.823 NM_026925
Pnlip
pancreatic lipase
chr10_-_126507271 7.802 NM_025982
Tspan31
tetraspanin 31
chr2_-_58419236 7.738 NM_001110204
NM_001110205
NM_007394
Acvr1


activin A receptor, type 1


chr5_+_93112640 7.701 Shroom3
shroom family member 3
chr7_-_4467556 7.681 NM_011618
Tnnt1
troponin T1, skeletal, slow
chr7_+_99709652 7.654 NM_001162918
NM_025515
Ccdc90b

coiled-coil domain containing 90B

chr5_+_97222355 7.612 NM_013470
Anxa3
annexin A3
chr8_-_47292863 7.478


chr7_+_146574969 7.443 NM_001127363
NM_183144
Inpp5a

inositol polyphosphate-5-phosphatase A

chr6_+_138089041 7.437 NM_019946
Mgst1
microsomal glutathione S-transferase 1
chrX_+_70728994 7.385 Bgn
biglycan
chr13_+_49639799 7.363 NM_001172481
NM_025711
Aspn

asporin

chr3_-_10208480 7.328 Fabp4
Fabp9
fatty acid binding protein 4, adipocyte
fatty acid binding protein 9, testis
chr1_+_173155184 7.310 NM_013474
Apoa2
apolipoprotein A-II

Gene Ontology Analysis

Gene overrepresentation in process category:

Enrichment   P-value GO Accession GO Term
1.89 1.63e-12 GO:0009653 anatomical structure morphogenesis
1.58 6.96e-12 GO:0048856 anatomical structure development
1.51 1.42e-11 GO:0032502 developmental process
1.61 2.57e-11 GO:0048731 system development
2.09 3.00e-11 GO:0009888 tissue development
1.70 2.54e-10 GO:0048513 organ development
1.50 7.20e-10 GO:0007275 multicellular organismal development
2.34 4.64e-09 GO:0072358 cardiovascular system development
2.34 4.64e-09 GO:0072359 circulatory system development
1.50 2.76e-07 GO:0048519 negative regulation of biological process
1.53 2.77e-07 GO:0048523 negative regulation of cellular process
1.57 1.06e-06 GO:0065008 regulation of biological quality
2.04 1.30e-06 GO:0009887 organ morphogenesis
2.47 2.24e-06 GO:0001944 vasculature development
2.54 2.58e-06 GO:0001568 blood vessel development
2.72 2.88e-06 GO:0048514 blood vessel morphogenesis
1.51 5.63e-06 GO:0048869 cellular developmental process
1.55 6.15e-06 GO:0042221 response to chemical stimulus
1.51 1.18e-05 GO:0030154 cell differentiation
2.58 1.58e-05 GO:0061061 muscle structure development
2.50 2.02e-05 GO:0007507 heart development
1.70 5.00e-05 GO:0050793 regulation of developmental process
1.93 5.05e-05 GO:0007155 cell adhesion
1.92 7.27e-05 GO:0022610 biological adhesion
1.77 7.51e-05 GO:0048468 cell development
2.34 9.10e-05 GO:0032787 monocarboxylic acid metabolic process
1.38 9.83e-05 GO:0016043 cellular component organization
1.73 1.02e-04 GO:0042127 regulation of cell proliferation
1.20 1.07e-04 GO:0008152 metabolic process
1.76 1.81e-04 GO:0006629 lipid metabolic process
2.76 2.52e-04 GO:0001525 angiogenesis
2.18 2.55e-04 GO:0008285 negative regulation of cell proliferation
3.13 4.46e-04 GO:0003012 muscle system process
1.36 5.09e-04 GO:0048518 positive regulation of biological process
1.76 5.27e-04 GO:0055114 oxidation-reduction process
2.12 6.29e-04 GO:0048729 tissue morphogenesis
5.05 6.79e-04 GO:0007266 Rho protein signal transduction
1.52 6.81e-04 GO:0051239 regulation of multicellular organismal process
1.98 6.90e-04 GO:0032989 cellular component morphogenesis
1.70 6.99e-04 GO:2000026 regulation of multicellular organismal development
1.74 7.10e-04 GO:0045595 regulation of cell differentiation
1.92 8.64e-04 GO:0048646 anatomical structure formation involved in morphogenesis
1.62 9.55e-04 GO:0010033 response to organic substance
1.33 1.25e-03 GO:0071840 cellular component organization or biogenesis
2.72 1.28e-03 GO:0007517 muscle organ development
2.03 1.44e-03 GO:0060429 epithelium development
1.20 1.69e-03 GO:0044238 primary metabolic process
2.80 1.71e-03 GO:0006457 protein folding
2.93 2.70e-03 GO:0030324 lung development
2.79 2.82e-03 GO:0060541 respiratory system development
2.89 3.66e-03 GO:0030323 respiratory tube development
2.63 4.08e-03 GO:0060537 muscle tissue development
2.37 4.33e-03 GO:0048732 gland development
1.30 4.69e-03 GO:0051179 localization
1.94 4.83e-03 GO:0000902 cell morphogenesis
2.65 5.13e-03 GO:0050678 regulation of epithelial cell proliferation
3.04 6.40e-03 GO:0006936 muscle contraction
3.46 7.72e-03 GO:0006639 acylglycerol metabolic process
5.25 8.67e-03 GO:0044259 multicellular organismal macromolecule metabolic process
3.18 8.83e-03 GO:0006662 glycerol ether metabolic process
2.07 1.03e-02 GO:0040012 regulation of locomotion
1.99 1.04e-02 GO:0009725 response to hormone stimulus
5.69 1.05e-02 GO:0030199 collagen fibril organization
3.37 1.14e-02 GO:0006638 neutral lipid metabolic process
1.97 1.17e-02 GO:0090066 regulation of anatomical structure size
2.00 1.24e-02 GO:0007167 enzyme linked receptor protein signaling pathway
3.11 1.25e-02 GO:0018904 organic ether metabolic process
1.43 1.25e-02 GO:0006950 response to stress
4.67 1.26e-02 GO:0010464 regulation of mesenchymal cell proliferation
1.92 1.31e-02 GO:0009719 response to endogenous stimulus
1.75 1.57e-02 GO:0040011 locomotion
1.32 1.72e-02 GO:0019538 protein metabolic process
1.72 1.94e-02 GO:0019752 carboxylic acid metabolic process
1.72 1.94e-02 GO:0043436 oxoacid metabolic process
3.53 2.04e-02 GO:0006641 triglyceride metabolic process
1.71 2.27e-02 GO:0006082 organic acid metabolic process
1.78 2.34e-02 GO:0051094 positive regulation of developmental process
1.70 2.35e-02 GO:0070887 cellular response to chemical stimulus
2.74 2.37e-02 GO:0003007 heart morphogenesis
1.70 2.53e-02 GO:0042180 cellular ketone metabolic process
2.55 2.59e-02 GO:0014706 striated muscle tissue development
4.09 2.61e-02 GO:0031016 pancreas development
2.06 2.96e-02 GO:2000145 regulation of cell motility
4.33 3.04e-02 GO:0043588 skin development
2.38 3.09e-02 GO:0040017 positive regulation of locomotion
1.72 3.20e-02 GO:0044255 cellular lipid metabolic process
1.32 3.21e-02 GO:0048522 positive regulation of cellular process
2.17 3.23e-02 GO:0032101 regulation of response to external stimulus
5.10 3.29e-02 GO:0032963 collagen metabolic process
4.65 3.32e-02 GO:0002053 positive regulation of mesenchymal cell proliferation
2.80 4.21e-02 GO:0030278 regulation of ossification
2.07 4.25e-02 GO:0001501 skeletal system development
4.52 4.49e-02 GO:0044236 multicellular organismal metabolic process
2.04 4.95e-02 GO:0030334 regulation of cell migration

Gene overrepresentation in compartment category:

Enrichment   P-value GO Accession GO Term
1.34 1.85e-21 GO:0005737 cytoplasm
1.41 7.10e-17 GO:0044444 cytoplasmic part
1.21 9.28e-14 GO:0044424 intracellular part
1.20 3.96e-13 GO:0005622 intracellular
2.06 6.14e-13 GO:0044421 extracellular region part
1.66 1.88e-10 GO:0005576 extracellular region
2.08 1.26e-09 GO:0005615 extracellular space
2.66 2.60e-09 GO:0031012 extracellular matrix
1.20 4.22e-09 GO:0043226 organelle
2.76 4.65e-09 GO:0005578 proteinaceous extracellular matrix
1.20 4.70e-09 GO:0043229 intracellular organelle
1.77 1.40e-08 GO:0000267 cell fraction
3.58 2.40e-07 GO:0043292 contractile fiber
3.67 2.50e-07 GO:0044420 extracellular matrix part
1.74 5.93e-06 GO:0005626 insoluble fraction
3.52 8.97e-06 GO:0044449 contractile fiber part
1.31 3.84e-05 GO:0071944 cell periphery
3.24 5.07e-05 GO:0030016 myofibril
1.08 5.26e-05 GO:0005623 cell
1.08 5.26e-05 GO:0044464 cell part
1.70 5.58e-05 GO:0005624 membrane fraction
1.51 8.97e-05 GO:0005739 mitochondrion
1.17 9.15e-05 GO:0043231 intracellular membrane-bounded organelle
1.17 9.45e-05 GO:0043227 membrane-bounded organelle
1.45 1.73e-04 GO:0044459 plasma membrane part
2.41 3.03e-04 GO:0016323 basolateral plasma membrane
3.47 5.44e-04 GO:0005604 basement membrane
1.28 5.79e-04 GO:0005886 plasma membrane
1.89 7.07e-04 GO:0009986 cell surface
3.21 1.03e-03 GO:0030017 sarcomere
2.11 2.48e-03 GO:0015629 actin cytoskeleton
3.21 3.35e-03 GO:0042383 sarcolemma
2.13 5.47e-03 GO:0045177 apical part of cell
2.93 7.63e-03 GO:0016327 apicolateral plasma membrane
1.90 1.04e-02 GO:0005625 soluble fraction
2.13 1.21e-02 GO:0005911 cell-cell junction
1.40 1.85e-02 GO:0005829 cytosol
2.83 1.99e-02 GO:0043296 apical junction complex
1.46 2.13e-02 GO:0042995 cell projection
1.94 2.23e-02 GO:0048471 perinuclear region of cytoplasm
4.75 2.39e-02 GO:0009925 basal plasma membrane
1.39 2.43e-02 GO:0005856 cytoskeleton
1.88 3.29e-02 GO:0042598 vesicular fraction
1.46 3.82e-02 GO:0005783 endoplasmic reticulum
6.82 4.18e-02 GO:0005583 fibrillar collagen

Gene overrepresentation in function category:

Enrichment   P-value GO Accession GO Term
1.44 1.82e-20 GO:0005515 protein binding
1.21 1.66e-13 GO:0005488 binding
1.73 2.91e-06 GO:0005102 receptor binding
2.18 1.30e-05 GO:0005198 structural molecule activity
3.38 6.44e-05 GO:0019838 growth factor binding
1.95 6.51e-05 GO:0008092 cytoskeletal protein binding
9.86 1.06e-04 GO:0048407 platelet-derived growth factor binding
1.86 9.48e-04 GO:0005509 calcium ion binding
3.76 1.97e-03 GO:0005178 integrin binding
2.53 6.70e-03 GO:0001871 pattern binding
2.53 6.70e-03 GO:0030247 polysaccharide binding
5.10 7.53e-03 GO:0005201 extracellular matrix structural constituent
1.76 8.21e-03 GO:0019904 protein domain specific binding
1.88 2.11e-02 GO:0032403 protein complex binding
5.63 2.51e-02 GO:0001968 fibronectin binding
2.96 2.93e-02 GO:0051082 unfolded protein binding
1.53 3.81e-02 GO:0019899 enzyme binding
1.82 3.93e-02 GO:0030246 carbohydrate binding
4.22 4.75e-02 GO:0050840 extracellular matrix binding