Motif ID: IKZF1.p2

Z-value: 1.588


Transcription factors associated with IKZF1.p2:

Gene SymbolEntrez IDGene Name
Ikzf1 22778 IKAROS family zinc finger 1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ikzf1chr11_+_11586215-0.531.2e-14Click!


Activity profile for motif IKZF1.p2.

activity profile for motif IKZF1.p2


Sorted Z-values histogram for motif IKZF1.p2

Sorted Z-values for motif IKZF1.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of IKZF1.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_+_56040193 32.391 Gpm6a
glycoprotein m6a
chr8_+_56040211 31.644 Gpm6a
glycoprotein m6a
chr7_+_120909625 29.460 Spon1
spondin 1, (f-spondin) extracellular matrix protein
chr8_+_56040080 28.521 NM_153581
 Gpm6a
glycoprotein m6a
chr15_+_91881593 28.404 NM_001159648
 Cntn1
contactin 1
chr7_+_31092787 24.320 Clip3
CAP-GLY domain containing linker protein 3
chr8_+_56040445 21.809 Gpm6a
glycoprotein m6a
chr8_+_56040553 21.260 Gpm6a
glycoprotein m6a
chr4_-_151235861 21.072 NM_001081557
NM_001195565
 Camta1

calmodulin binding transcription activator 1

chr7_-_82454147 20.442 NM_153579
 Sv2b
synaptic vesicle glycoprotein 2 b
chr14_-_71035662 20.230 Epb4.9
erythrocyte protein band 4.9
chr13_+_54472806 20.176 Cplx2
complexin 2
chr12_-_11443284 19.706 NM_012038
 Vsnl1
visinin-like 1
chr8_-_67171805 18.671 NM_013494
 Cpe
carboxypeptidase E
chr8_-_67171692 18.368 Cpe
carboxypeptidase E
chr7_-_112717810 17.950 Apbb1
amyloid beta (A4) precursor protein-binding, family B, member 1
chr14_-_119324535 17.839 Dzip1
DAZ interacting protein 1
chr16_+_91270319 17.334 Olig1
oligodendrocyte transcription factor 1
chr3_+_90346956 17.033 S100a16
S100 calcium binding protein A16
chr1_-_79436564 16.935 NM_009129
 Scg2
secretogranin II

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 34 entries
Enrichment   P-value GO Accession GO Term
8.34 7.12e-04 GO:0055021 regulation of cardiac muscle tissue growth
7.90 1.28e-03 GO:0055024 regulation of cardiac muscle tissue development
7.90 1.28e-03 GO:0060420 regulation of heart growth
7.30 4.79e-02 GO:0060043 regulation of cardiac muscle cell proliferation
5.29 1.09e-03 GO:0046620 regulation of organ growth
2.69 4.06e-03 GO:0043062 extracellular structure organization
2.66 1.12e-02 GO:0060537 muscle tissue development
2.54 1.87e-03 GO:0007409 axonogenesis
2.41 7.04e-05 GO:0031175 neuron projection development
2.35 5.69e-03 GO:0048812 neuron projection morphogenesis
2.34 4.57e-04 GO:0032990 cell part morphogenesis
2.31 1.48e-02 GO:0048667 cell morphogenesis involved in neuron differentiation
2.27 1.85e-03 GO:0048858 cell projection morphogenesis
2.25 9.51e-04 GO:0019226 transmission of nerve impulse
2.25 9.51e-04 GO:0035637 multicellular organismal signaling
2.23 6.47e-05 GO:0048666 neuron development
2.21 5.14e-03 GO:0000904 cell morphogenesis involved in differentiation
2.20 3.26e-02 GO:0007268 synaptic transmission
2.18 2.12e-05 GO:0030030 cell projection organization
1.93 2.22e-03 GO:0030182 neuron differentiation

Gene overrepresentation in compartment category:

Showing 1 to 20 of 23 entries
Enrichment   P-value GO Accession GO Term
5.75 1.46e-03 GO:0030672 synaptic vesicle membrane
2.87 2.76e-02 GO:0008021 synaptic vesicle
2.65 1.36e-02 GO:0033267 axon part
2.27 1.07e-04 GO:0031012 extracellular matrix
2.12 9.31e-05 GO:0044463 cell projection part
2.12 6.38e-03 GO:0005578 proteinaceous extracellular matrix
2.11 6.89e-03 GO:0030425 dendrite
2.10 1.52e-05 GO:0045202 synapse
2.10 1.50e-03 GO:0044456 synapse part
2.02 5.03e-03 GO:0044297 cell body
1.98 2.82e-05 GO:0043005 neuron projection
1.97 1.87e-02 GO:0043025 neuronal cell body
1.86 2.04e-04 GO:0030054 cell junction
1.78 5.81e-07 GO:0042995 cell projection
1.61 1.86e-02 GO:0031982 vesicle
1.47 2.57e-02 GO:0000267 cell fraction
1.38 1.41e-02 GO:0044459 plasma membrane part
1.29 9.58e-04 GO:0071944 cell periphery
1.28 2.07e-03 GO:0005886 plasma membrane
1.23 3.03e-04 GO:0044444 cytoplasmic part

Gene overrepresentation in function category:

Showing 1 to 7 of 7 entries
Enrichment   P-value GO Accession GO Term
3.17 3.35e-02 GO:0005088 Ras guanyl-nucleotide exchange factor activity
2.25 4.37e-03 GO:0005083 small GTPase regulator activity
2.04 9.34e-04 GO:0060589 nucleoside-triphosphatase regulator activity
1.97 4.62e-03 GO:0030695 GTPase regulator activity
1.56 4.05e-02 GO:0030234 enzyme regulator activity
1.30 9.59e-08 GO:0005515 protein binding
1.15 6.79e-06 GO:0005488 binding