Motif ID: IKZF2.p2

Z-value: 1.140


Transcription factors associated with IKZF2.p2:

Gene SymbolEntrez IDGene Name
Ikzf2 22779 IKAROS family zinc finger 2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ikzf2chr1_-_697323730.172.1e-02Click!


Activity profile for motif IKZF2.p2.

activity profile for motif IKZF2.p2


Sorted Z-values histogram for motif IKZF2.p2

Sorted Z-values for motif IKZF2.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of IKZF2.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_72091188 20.622 NM_008069
 Gabrb1
gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
chr8_+_56122680 16.029 Gpm6a
glycoprotein m6a
chrX_+_132806184 14.893 Ngfrap1
nerve growth factor receptor (TNFRSF16) associated protein 1
chr17_-_90436488 14.527 Nrxn1
neurexin I
chr6_-_126658429 13.899


chr9_-_49311823 12.943 Ncam1
neural cell adhesion molecule 1
chrX_+_131252542 12.802 Armcx1
armadillo repeat containing, X-linked 1
chrX_+_131252456 12.149 NM_001166377
NM_001166378
NM_001166379
NM_001166380
NM_030066
 Armcx1




armadillo repeat containing, X-linked 1




chr9_-_117160916 11.660 Rbms3
RNA binding motif, single stranded interacting protein
chr9_-_117161234 11.652 Rbms3
RNA binding motif, single stranded interacting protein
chr9_-_117161564 10.645 NM_001172122
NM_001172123
NM_001172124
NM_001172126
NM_178660
 Rbms3




RNA binding motif, single stranded interacting protein




chr4_+_104829963 9.883 Ppap2b
phosphatidic acid phosphatase type 2B
chr4_+_104829867 9.273 Ppap2b
phosphatidic acid phosphatase type 2B
chr9_-_21820860 8.973 Elavl3
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 3 (Hu antigen C)
chr16_-_36334417 8.859 NM_001001332
 BC117090
cDNA sequence BC1179090
chr2_+_121183509 8.489 Ckmt1
creatine kinase, mitochondrial 1, ubiquitous
chr11_-_79317583 8.190 NM_019409
 Omg
oligodendrocyte myelin glycoprotein
chr11_-_79317471 8.119 Omg
oligodendrocyte myelin glycoprotein
chr6_+_30756073 7.736 Copg2as2
coatomer protein complex, subunit gamma 2, antisense 2
chr4_+_104829951 7.652 NM_080555
 Ppap2b
phosphatidic acid phosphatase type 2B

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 21 entries
Enrichment   P-value GO Accession GO Term
3.16 2.17e-02 GO:0061039 ovum-producing ovary development
3.00 1.62e-02 GO:0008585 female gonad development
2.89 4.99e-02 GO:0042698 ovulation cycle
2.82 1.72e-02 GO:0031589 cell-substrate adhesion
1.92 4.89e-07 GO:0007155 cell adhesion
1.90 7.90e-07 GO:0022610 biological adhesion
1.82 4.78e-02 GO:0019226 transmission of nerve impulse
1.82 4.78e-02 GO:0035637 multicellular organismal signaling
1.74 5.51e-03 GO:0048585 negative regulation of response to stimulus
1.62 1.07e-02 GO:0007154 cell communication
1.54 3.24e-02 GO:0048699 generation of neurons
1.52 3.00e-04 GO:0007399 nervous system development
1.51 3.77e-02 GO:0022008 neurogenesis
1.50 2.69e-02 GO:0042592 homeostatic process
1.46 1.88e-02 GO:0010646 regulation of cell communication
1.36 9.30e-03 GO:0065008 regulation of biological quality
1.34 5.48e-04 GO:0048731 system development
1.32 3.93e-04 GO:0048856 anatomical structure development
1.30 1.76e-04 GO:0032502 developmental process
1.29 9.85e-04 GO:0007275 multicellular organismal development

Gene overrepresentation in compartment category:

Showing 1 to 20 of 26 entries
Enrichment   P-value GO Accession GO Term
6.14 1.69e-02 GO:0005583 fibrillar collagen
2.68 2.28e-02 GO:0030426 growth cone
2.58 3.86e-02 GO:0030427 site of polarized growth
2.34 2.69e-02 GO:0044420 extracellular matrix part
2.05 2.51e-04 GO:0005578 proteinaceous extracellular matrix
1.98 3.06e-03 GO:0030424 axon
1.92 6.38e-04 GO:0044456 synapse part
1.91 4.47e-06 GO:0045202 synapse
1.91 1.17e-03 GO:0031012 extracellular matrix
1.85 2.96e-06 GO:0043005 neuron projection
1.70 1.30e-04 GO:0030054 cell junction
1.70 1.20e-02 GO:0044463 cell projection part
1.66 7.25e-08 GO:0042995 cell projection
1.59 5.69e-05 GO:0005626 insoluble fraction
1.57 2.44e-04 GO:0005624 membrane fraction
1.57 2.36e-03 GO:0005615 extracellular space
1.55 1.39e-04 GO:0044421 extracellular region part
1.50 8.49e-05 GO:0000267 cell fraction
1.44 6.43e-06 GO:0005576 extracellular region
1.42 3.08e-02 GO:0005794 Golgi apparatus

Gene overrepresentation in function category:

Showing 1 to 8 of 8 entries
Enrichment   P-value GO Accession GO Term
9.51 1.96e-02 GO:0031994 insulin-like growth factor I binding
2.61 6.90e-03 GO:0019838 growth factor binding
1.87 3.35e-02 GO:0004857 enzyme inhibitor activity
1.64 1.44e-02 GO:0005509 calcium ion binding
1.56 1.00e-03 GO:0030234 enzyme regulator activity
1.53 3.22e-03 GO:0019899 enzyme binding
1.30 6.46e-12 GO:0005515 protein binding
1.14 4.88e-07 GO:0005488 binding