• All motifs sorted by activity significance
• All samples sorted alphabetically

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)

Motif ID: KLF4.p3

Z-value: 2.797

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr7_+_28232980	42.120	NM_144923	Blvrb	biliverdin reductase B (flavin reductase (NADPH))
chr9_-_65427840	41.483	NM_153119	Plekho2	pleckstrin homology domain containing, family O member 2
chr5_-_114358647	38.270	NM_011779	Coro1c	coronin, actin binding protein 1C
chrX_-_71491851	37.553	NM_010227	Flna	filamin, alpha
chr4_-_55545337	36.359	NM_010637	Klf4	Kruppel-like factor 4 (gut)
chr17_+_29627697	35.882		Pim1	proviral integration site 1
chr7_+_28233013	35.253		Blvrb	biliverdin reductase B (flavin reductase (NADPH))
chrX_-_71491736	32.691		Flna	filamin, alpha
chr4_-_134828699	31.381		Clic4	chloride intracellular channel 4 (mitochondrial)
chr5_+_145875080	29.607	NM_023142	Arpc1b	actin related protein 2/3 complex, subunit 1B
chr12_+_8778260	29.218		Sdc1	syndecan 1
chr7_+_52273317	28.947	NM_009101	Rras	Harvey rat sarcoma oncogene, subgroup R
chrX_+_93291377	28.039	NM_010833	Msn	moesin
chr7_+_26471968	27.452	NM_011577	Tgfb1	transforming growth factor, beta 1
chr2_-_167174531	26.692	NM_019835	B4galt5	UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 5
chr18_+_70727897	26.613	NM_010773	Mbd2	methyl-CpG binding domain protein 2
chr14_+_21748602	26.529		Vcl	vinculin
chr11_+_54911540	26.181	NM_010299	Gm2a	GM2 ganglioside activator protein
chr14_+_21748646	25.544	NM_009502	Vcl	vinculin
chr5_+_65194749	25.098	NM_008453	Klf3	Kruppel-like factor 3 (basic)
chr5_+_65194784	24.878		Klf3	Kruppel-like factor 3 (basic)
chr5_+_53132801	24.870	NM_025951 NM_028744	Pi4k2b	phosphatidylinositol 4-kinase type 2 beta
chr12_+_8778152	24.857		Sdc1	syndecan 1
chr2_+_32731648	24.770	NM_146119	Fam129b	family with sequence similarity 129, member B
chr1_-_155179844	24.596	NM_010683	Lamc1	laminin, gamma 1
chr4_-_55545211	24.099		Klf4	Kruppel-like factor 4 (gut)
chr9_+_123387818	23.339	NM_013860	Limd1	LIM domains containing 1
chr17_-_71201055	23.156	NM_001164075	Tgif1	TGFB-induced factor homeobox 1
chr6_-_72908018	22.882	NM_001039392	Tmsb10	thymosin, beta 10
chr7_+_133903186	22.400		Mapk3	mitogen-activated protein kinase 3
chr7_+_3290622	22.198		Myadm	myeloid-associated differentiation marker
chr12_+_8778201	22.122	NM_011519	Sdc1	syndecan 1
chr11_-_102157904	21.823	NM_001098836 NM_001098837	Atxn7l3	ataxin 7-like 3
chr17_+_24873606	21.470		Sepx1	selenoprotein X 1
chr5_+_53132872	21.262		Pi4k2b	phosphatidylinositol 4-kinase type 2 beta
chr11_-_70468019	21.252		Pfn1	profilin 1
chr7_-_20214596	21.083	NM_009046	Relb	avian reticuloendotheliosis viral (v-rel) oncogene related B
chr7_-_108971734	21.012
chr2_-_143836838	20.815	NM_024281 NM_133626	Rrbp1	ribosome binding protein 1
chr4_-_59562054	20.722	NM_144904 NM_178164	Rod1	ROD1 regulator of differentiation 1 (S. pombe)
chr7_-_19856882	20.706		Vasp	vasodilator-stimulated phosphoprotein
chr5_-_141306258	20.529	NM_010302	Gna12	guanine nucleotide binding protein, alpha 12
chr14_+_15179435	20.402		Il3ra	interleukin 3 receptor, alpha chain
chr7_+_133903118	20.308	NM_011952	Mapk3	mitogen-activated protein kinase 3
chr5_+_136559932	20.144		Rasa4	RAS p21 protein activator 4
chr11_+_121563691	20.000	NM_144797	Metrnl	meteorin, glial cell differentiation regulator-like
chr8_-_11478623	19.784		Rab20	RAB20, member RAS oncogene family
chr8_+_47556503	19.576		Acsl1	acyl-CoA synthetase long-chain family member 1
chr19_+_7049639	19.543		Ppp1r14b	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr13_+_54890763	19.349	NM_028841	Tspan17	tetraspanin 17
chr6_+_28373521	19.110	NM_007480	Arf5	ADP-ribosylation factor 5
chr4_+_118100682	18.896	NM_001039175 NM_019422	Elovl1	elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr6_-_72908741	18.880	NM_001190327	Tmsb10	thymosin, beta 10
chr12_+_33505307	18.385		Nampt	nicotinamide phosphoribosyltransferase
chr4_-_40800995	18.337	NM_022305	B4galt1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr19_+_7049425	18.068	NM_008889	Ppp1r14b	protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr2_-_169956719	18.014	NM_001033299	Zfp217	zinc finger protein 217
chr2_-_35192443	17.923	NM_013515	Stom	stomatin
chr15_+_78813475	17.598	NM_001024716	Triobp	TRIO and F-actin binding protein
chr17_+_45823255	17.580	NM_026732	Mrpl14	mitochondrial ribosomal protein L14
chr13_-_49311308	17.532	NM_026738	1110007C09Rik	RIKEN cDNA 1110007C09 gene
chr6_-_72908352	17.351	NM_025284	Tmsb10	thymosin, beta 10
chr7_-_20334814	17.107		Pvrl2	poliovirus receptor-related 2
chr11_-_117830455	17.024		Socs3	suppressor of cytokine signaling 3
chr7_-_150646883	16.915	NM_001161624 NM_009876	Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)
chr17_+_24873561	16.904	NM_013759	Sepx1	selenoprotein X 1
chr5_+_65194627	16.831		Klf3	Kruppel-like factor 3 (basic)
chr17_+_29627950	16.828	NM_008842	Pim1	proviral integration site 1
chr15_+_81977766	16.731		Srebf2	sterol regulatory element binding factor 2
chr16_-_17928207	16.677		Slc25a1	solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
chr2_+_79475581	16.656	NM_080558	Ssfa2	sperm specific antigen 2
chr4_-_94718846	16.594	NM_010591	Jun	Jun oncogene
chr7_+_3290516	16.574	NM_016969 NM_001093765	Myadm	myeloid-associated differentiation marker
chr8_-_13494457	16.516	NM_019521	Gas6	growth arrest specific 6
chr17_+_57388873	16.459	NM_134125	Trip10	thyroid hormone receptor interactor 10
chr4_+_138748812	16.364	NM_009798 NM_001037761	Capzb	capping protein (actin filament) muscle Z-line, beta
chr7_-_19857195	16.168	NM_009499	Vasp	vasodilator-stimulated phosphoprotein
chr11_-_117830554	16.160	NM_007707	Socs3	suppressor of cytokine signaling 3
chr9_-_88376937	16.110	NM_019666 NM_019796	Syncrip	synaptotagmin binding, cytoplasmic RNA interacting protein
chr10_+_57786213	16.095	NM_026148	Lims1	LIM and senescent cell antigen-like domains 1
chr14_-_31439299	15.995		Prkcd	protein kinase C, delta
chr8_+_47556353	15.955	NM_007981	Acsl1	acyl-CoA synthetase long-chain family member 1
chr15_+_78757148	15.835	NM_008495	Lgals1	lectin, galactose binding, soluble 1
chr1_-_121401236	15.782	NM_022327	Ralb	v-ral simian leukemia viral oncogene homolog B (ras related)
chr4_-_133443662	15.639	NM_009097	Rps6ka1	ribosomal protein S6 kinase polypeptide 1
chrX_+_70962057	15.547		Abcd1	ATP-binding cassette, sub-family D (ALD), member 1
chr11_+_109224275	15.502
chr7_-_52309439	15.389		Prrg2	proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr4_-_46614726	15.343	NM_001164804	Coro2a	coronin, actin binding protein 2A
chr15_+_78813524	15.317		Triobp	TRIO and F-actin binding protein
chr10_-_117282901	15.249		Rap1b	RAS related protein 1b
chr11_+_117061031	15.126		Sept9	septin 9
chr19_-_7044198	15.042	NM_008874	Plcb3	phospholipase C, beta 3
chr11_-_62462024	15.002	NM_198861	BC046404	cDNA sequence BC046404
chr12_-_86113948	14.867	NM_023409	Npc2	Niemann Pick type C2
chr7_-_19857121	14.844		Vasp	vasodilator-stimulated phosphoprotein
chr15_+_78757171	14.781		Lgals1	lectin, galactose binding, soluble 1
chr2_+_118727248	14.736	NM_001045523	Bahd1	bromo adjacent homology domain containing 1
chr13_-_104899571	14.561	NM_029447	Nln	neurolysin (metallopeptidase M3 family)
chr11_-_101327431	14.529	NM_012037	Vat1	vesicle amine transport protein 1 homolog (T californica)
chr10_+_95403283	14.503	NM_001001932	Eea1	early endosome antigen 1
chr1_+_36125177	14.420	NM_015818	Hs6st1	heparan sulfate 6-O-sulfotransferase 1
chr7_+_26067197	14.384	NM_001110131 NM_001110132 NM_027882	Cic	capicua homolog (Drosophila)
chr7_-_150646758	14.281		Cdkn1c	cyclin-dependent kinase inhibitor 1C (P57)
chr2_-_60800904	14.229		Rbms1	RNA binding motif, single stranded interacting protein 1
chr1_+_36125380	14.207		Hs6st1	heparan sulfate 6-O-sulfotransferase 1
chr5_+_136559785	14.167	NM_001039103 NM_133914	Rasa4	RAS p21 protein activator 4
chr5_-_122286761	13.966	NM_008507	Sh2b3	SH2B adaptor protein 3
chr9_-_122203459	13.956		Ano10	anoctamin 10
chr19_+_6276885	13.955	NM_010119	Ehd1	EH-domain containing 1
chr12_+_33505364	13.836		Nampt	nicotinamide phosphoribosyltransferase
chr7_-_105326687	13.790	NM_007602	Capn5	calpain 5
chr4_+_129190872	13.781		Marcksl1	MARCKS-like 1
chrX_+_139115908	13.711	NM_177592	Tmem164	transmembrane protein 164
chr12_+_33505175	13.691	NM_021524	Nampt	nicotinamide phosphoribosyltransferase
chr11_-_100599413	13.596	NM_024456	Rab5c	RAB5C, member RAS oncogene family
chr7_-_20334650	13.440		Pvrl2	poliovirus receptor-related 2
chr4_-_43058685	13.302		B230312A22Rik	RIKEN cDNA B230312A22 gene
chr3_+_145587194	13.284	NM_009740	Bcl10	B-cell leukemia/lymphoma 10
chr2_+_143741243	13.262		Dstn	destrin
chr7_-_105326751	13.239		Capn5	calpain 5
chr3_-_127599117	13.168	NM_027482	5730508B09Rik	RIKEN cDNA 5730508B09 gene
chr7_-_134170532	13.103		Maz	MYC-associated zinc finger protein (purine-binding transcription factor)
chr9_-_122203483	13.095	NM_133979	Ano10	anoctamin 10
chr5_+_123465266	13.079		Orai1	ORAI calcium release-activated calcium modulator 1
chr5_+_65194814	13.071		Klf3	Kruppel-like factor 3 (basic)
chr4_-_43059017	13.017	NM_172691	B230312A22Rik	RIKEN cDNA B230312A22 gene
chr5_+_130417868	12.922	NM_001001327 NM_027121	Vkorc1l1	vitamin K epoxide reductase complex, subunit 1-like 1
chr5_+_115956809	12.888		Pxn	paxillin
chr19_-_61304260	12.776	NM_009970	Csf2ra	colony stimulating factor 2 receptor, alpha, low-affinity (granulocyte-macrophage)
chr12_-_86113816	12.762		Npc2	Niemann Pick type C2
chr1_-_39634096	12.709	NM_001033135	Rnf149	ring finger protein 149
chr17_+_31701700	12.663	NM_016670	Pknox1	Pbx/knotted 1 homeobox
chr14_-_41780085	12.649	NM_145928	Tspan14	tetraspanin 14
chr16_+_77013880	12.631	NM_013918	Usp25	ubiquitin specific peptidase 25
chrX_+_156065141	12.619	NM_001135727	Sh3kbp1	SH3-domain kinase binding protein 1
chr6_+_42300005	12.610		Zyx	zyxin
chr10_-_117283020	12.544	NM_024457	Rap1b	RAS related protein 1b
chr16_-_17928270	12.544	NM_153150	Slc25a1	solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
chr1_-_182743632	12.534	NM_008210	H3f3a	H3 histone, family 3A
chr9_+_108208812	12.509		Rhoa	ras homolog gene family, member A
chr15_-_76028594	12.486	NM_201393	Plec	plectin
chr7_+_107641884	12.471		Ucp2	uncoupling protein 2 (mitochondrial, proton carrier)
chr18_+_70728508	12.430		Mbd2	methyl-CpG binding domain protein 2
chr5_+_136165013	12.424	NM_008898	Por	P450 (cytochrome) oxidoreductase
chr6_-_34860807	12.401	NM_001013366	Wdr91	WD repeat domain 91
chr4_-_134828503	12.377	NM_013885	Clic4	chloride intracellular channel 4 (mitochondrial)
chr4_+_47366162	12.358	NM_009370	Tgfbr1	transforming growth factor, beta receptor I
chr16_-_8672242	12.283	NM_025821	Carhsp1	calcium regulated heat stable protein 1
chr7_+_3290587	12.273		Myadm	myeloid-associated differentiation marker
chr16_-_8672226	12.265		Carhsp1	calcium regulated heat stable protein 1
chr17_-_45732442	12.138		Slc29a1	solute carrier family 29 (nucleoside transporters), member 1
chr10_-_90545406	12.128		Apaf1	apoptotic peptidase activating factor 1
chr7_-_140315030	12.112		Ctbp2	C-terminal binding protein 2
chr6_-_51962458	12.088	NM_018773	Skap2	src family associated phosphoprotein 2
chr11_-_97049143	12.085		Kpnb1	karyopherin (importin) beta 1
chr4_-_40800983	12.036		B4galt1	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1
chr5_-_109987907	11.921	NM_001164735 NM_016715	Crlf2	cytokine receptor-like factor 2
chr1_-_193006986	11.919		Atf3	activating transcription factor 3
chr2_-_75542552	11.886	NM_010902	Nfe2l2	nuclear factor, erythroid derived 2, like 2
chr14_+_15178886	11.886	NM_008369	Il3ra	interleukin 3 receptor, alpha chain
chr11_-_69509298	11.871		BC096441	cDNA sequence BC096441
chr12_+_17697623	11.809		Hpcal1	hippocalcin-like 1
chr9_+_7764067	11.794	NM_133739	Tmem123	transmembrane protein 123
chr2_+_71624985	11.774	NM_008397	Itga6	integrin alpha 6
chr5_+_145016060	11.757	NM_018772	Bri3	brain protein I3
chr8_-_125135240	11.711	NM_001193645 NM_016722	Galns	galactosamine (N-acetyl)-6-sulfate sulfatase
chr5_+_73305509	11.657	NM_001113423 NM_153567	Slain2	SLAIN motif family, member 2
chr11_+_117670970	11.649	NM_009304	Syngr2	synaptogyrin 2
chr9_-_21722533	11.600	NM_031874	Rab3d	RAB3D, member RAS oncogene family
chr11_-_69734709	11.482	NM_001166595	Eif5a	eukaryotic translation initiation factor 5A
chr7_-_87948093	11.474	NM_016721	Iqgap1	IQ motif containing GTPase activating protein 1
chr4_+_53024724	11.415	NM_025623	Nipsnap3b	nipsnap homolog 3B (C. elegans)
chr17_+_36002537	11.398	NM_001146711	2310014H01Rik	RIKEN cDNA 2310014H01 gene
chr2_-_76486033	11.382	NM_011871	Prkra	protein kinase, interferon inducible double stranded RNA dependent activator
chr5_-_129514313	11.381	NM_007941	Stx2	syntaxin 2
chr7_+_134628622	11.341	NM_010183	Fbrs	fibrosin
chr4_+_129190877	11.337		Marcksl1	MARCKS-like 1
chr5_+_144165615	11.316		Kdelr2	KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr13_+_75844906	11.261	NM_138953	Ell2	elongation factor RNA polymerase II 2
chr11_+_60745534	11.258	NM_008928	Map2k3	mitogen-activated protein kinase kinase 3
chr1_+_174430081	11.249		Tagln2	transgelin 2
chr7_-_134169938	11.242	NM_010772	Maz	MYC-associated zinc finger protein (purine-binding transcription factor)
chr2_+_13495963	11.242		Vim	vimentin
chrX_+_70962097	11.219		Abcd1	ATP-binding cassette, sub-family D (ALD), member 1
chr6_-_125444722	11.177	NM_007657	Cd9	CD9 antigen
chr3_-_104855832	11.174	NM_001163332 NM_001163333 NM_030249	Cttnbp2nl	CTTNBP2 N-terminal like
chr11_+_75469516	11.170	NM_001080775	Myo1c	myosin IC
chr12_-_17006921	11.143	NM_001161111 NM_172574	Pqlc3	PQ loop repeat containing
chr2_-_154394864	11.143		E2f1	E2F transcription factor 1
chr11_-_69509220	11.109		Tnfsf12	tumor necrosis factor (ligand) superfamily, member 12
chr19_-_5424694	11.101		Drap1	Dr1 associated protein 1 (negative cofactor 2 alpha)
chr3_-_89197124	11.078	NM_009565	Zbtb7b	zinc finger and BTB domain containing 7B
chr6_+_124613114	11.048	NM_145130	Lpcat3	lysophosphatidylcholine acyltransferase 3
chr12_+_86940285	11.038	NM_030887	Jdp2	Jun dimerization protein 2
chr5_+_140267449	10.985	NM_010757	Mafk	v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian)
chr2_+_28368766	10.940		Ralgds	ral guanine nucleotide dissociation stimulator
chrX_-_71674201	10.930		G6pdx	glucose-6-phosphate dehydrogenase X-linked
chrX_+_70961935	10.907	NM_007435	Abcd1	ATP-binding cassette, sub-family D (ALD), member 1
chr4_-_122563074	10.887	NM_007598	Cap1	CAP, adenylate cyclase-associated protein 1 (yeast)

Gene overrepresentation in process category:

Enrichment	P-value	GO Accession	GO Term
1.26	9.60e-60	GO:0044237	cellular metabolic process
1.22	2.36e-55	GO:0008152	metabolic process
1.24	5.78e-55	GO:0044238	primary metabolic process
1.30	1.58e-43	GO:0019222	regulation of metabolic process
1.27	1.21e-42	GO:0044260	cellular macromolecule metabolic process
1.31	2.66e-41	GO:0031323	regulation of cellular metabolic process
1.24	5.23e-40	GO:0043170	macromolecule metabolic process
1.31	6.49e-40	GO:0080090	regulation of primary metabolic process
1.34	3.91e-36	GO:0051171	regulation of nitrogen compound metabolic process
1.34	2.93e-35	GO:0019219	regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.30	2.12e-34	GO:0060255	regulation of macromolecule metabolic process
1.28	4.82e-34	GO:0006807	nitrogen compound metabolic process
1.29	1.70e-33	GO:0034641	cellular nitrogen compound metabolic process
1.33	1.67e-31	GO:0010468	regulation of gene expression
1.37	4.44e-31	GO:0048523	negative regulation of cellular process
1.29	1.32e-30	GO:0006139	nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.34	5.47e-29	GO:0048519	negative regulation of biological process
1.34	6.53e-29	GO:0051252	regulation of RNA metabolic process
1.31	1.49e-28	GO:0048518	positive regulation of biological process
1.32	6.45e-28	GO:2000112	regulation of cellular macromolecule biosynthetic process
1.30	1.42e-27	GO:0009889	regulation of biosynthetic process
1.30	1.62e-27	GO:0016043	cellular component organization
1.30	1.76e-27	GO:0031326	regulation of cellular biosynthetic process
1.29	2.51e-27	GO:0071840	cellular component organization or biogenesis
1.31	1.43e-26	GO:0010556	regulation of macromolecule biosynthetic process
1.33	4.07e-26	GO:0006355	regulation of transcription, DNA-dependent
1.27	8.34e-26	GO:0044249	cellular biosynthetic process
1.40	1.49e-25	GO:0048583	regulation of response to stimulus
1.46	2.62e-25	GO:0009966	regulation of signal transduction
1.26	6.00e-25	GO:0032502	developmental process
1.27	7.16e-25	GO:0009058	biosynthetic process
1.26	1.86e-24	GO:0051179	localization
1.30	1.95e-23	GO:0048522	positive regulation of cellular process
1.28	6.35e-23	GO:0048856	anatomical structure development
1.27	6.41e-23	GO:0007275	multicellular organismal development
1.32	1.67e-22	GO:0071842	cellular component organization at cellular level
1.09	2.06e-22	GO:0009987	cellular process
1.28	2.18e-22	GO:0006810	transport
1.40	2.43e-22	GO:0023051	regulation of signaling
1.28	3.27e-22	GO:0051234	establishment of localization
1.31	4.91e-22	GO:0071841	cellular component organization or biogenesis at cellular level
1.29	4.79e-21	GO:0048731	system development
1.27	1.30e-20	GO:0090304	nucleic acid metabolic process
1.38	4.01e-20	GO:0006996	organelle organization
1.27	3.87e-19	GO:0010467	gene expression
1.27	2.43e-18	GO:0034645	cellular macromolecule biosynthetic process
1.27	2.62e-18	GO:0009059	macromolecule biosynthetic process
1.27	1.75e-17	GO:0016070	RNA metabolic process
1.31	9.63e-17	GO:0006351	transcription, DNA-dependent
1.31	1.69e-16	GO:0032774	RNA biosynthetic process
1.29	2.41e-16	GO:0030154	cell differentiation
1.33	4.21e-16	GO:0065009	regulation of molecular function
1.28	1.09e-15	GO:0048869	cellular developmental process
1.39	1.87e-15	GO:0009892	negative regulation of metabolic process
1.26	2.00e-15	GO:0044267	cellular protein metabolic process
1.31	4.00e-15	GO:0044281	small molecule metabolic process
1.40	8.42e-15	GO:0031324	negative regulation of cellular metabolic process
1.32	1.99e-14	GO:0051239	regulation of multicellular organismal process
1.33	5.11e-14	GO:0009653	anatomical structure morphogenesis
1.43	6.93e-14	GO:0051128	regulation of cellular component organization
1.28	1.38e-13	GO:0043412	macromolecule modification
1.29	1.50e-13	GO:0006464	protein modification process
1.38	1.57e-13	GO:0010941	regulation of cell death
1.22	1.63e-13	GO:0019538	protein metabolic process
1.38	2.28e-13	GO:0010605	negative regulation of macromolecule metabolic process
1.38	2.58e-13	GO:0006357	regulation of transcription from RNA polymerase II promoter
1.42	3.04e-13	GO:0009790	embryo development
1.27	4.78e-13	GO:0065008	regulation of biological quality
1.43	5.37e-13	GO:0009890	negative regulation of biosynthetic process
1.78	6.17e-13	GO:0030029	actin filament-based process
1.48	9.99e-13	GO:0051253	negative regulation of RNA metabolic process
1.80	1.01e-12	GO:0030036	actin cytoskeleton organization
1.43	1.07e-12	GO:0031327	negative regulation of cellular biosynthetic process
1.37	1.56e-12	GO:0043067	regulation of programmed cell death
1.34	1.60e-12	GO:0033036	macromolecule localization
1.45	1.61e-12	GO:0010629	negative regulation of gene expression
1.37	2.12e-12	GO:0006793	phosphorus metabolic process
1.37	2.22e-12	GO:0042981	regulation of apoptosis
1.34	2.23e-12	GO:0050790	regulation of catalytic activity
1.37	2.38e-12	GO:0006796	phosphate metabolic process
1.27	2.45e-12	GO:0048513	organ development
1.44	2.63e-12	GO:0051172	negative regulation of nitrogen compound metabolic process
1.47	4.81e-12	GO:0045892	negative regulation of transcription, DNA-dependent
1.44	5.66e-12	GO:2000113	negative regulation of cellular macromolecule biosynthetic process
1.43	5.70e-12	GO:0010558	negative regulation of macromolecule biosynthetic process
1.44	9.08e-12	GO:0045934	negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.32	6.44e-11	GO:0007399	nervous system development
1.34	6.50e-11	GO:0010646	regulation of cell communication
1.49	9.51e-11	GO:0009792	embryo development ending in birth or egg hatching
1.50	1.00e-10	GO:0048585	negative regulation of response to stimulus
1.33	1.97e-10	GO:0035556	intracellular signal transduction
1.49	2.05e-10	GO:0043009	chordate embryonic development
1.53	2.77e-10	GO:0000122	negative regulation of transcription from RNA polymerase II promoter
1.33	5.21e-10	GO:0008104	protein localization
1.52	5.41e-10	GO:0010648	negative regulation of cell communication
1.55	5.91e-10	GO:0009968	negative regulation of signal transduction
1.52	8.37e-10	GO:0023057	negative regulation of signaling
1.35	8.90e-10	GO:0009888	tissue development
1.28	1.05e-09	GO:0009893	positive regulation of metabolic process
1.37	1.31e-09	GO:0045184	establishment of protein localization
1.50	1.67e-09	GO:0007010	cytoskeleton organization
1.35	1.72e-09	GO:0045935	positive regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
1.41	2.41e-09	GO:0012501	programmed cell death
1.60	3.13e-09	GO:0033043	regulation of organelle organization
1.34	5.57e-09	GO:0051173	positive regulation of nitrogen compound metabolic process
1.41	6.18e-09	GO:0006915	apoptosis
1.28	6.77e-09	GO:0010604	positive regulation of macromolecule metabolic process
1.36	7.79e-09	GO:0015031	protein transport
1.34	8.23e-09	GO:2000026	regulation of multicellular organismal development
1.38	1.06e-08	GO:0016265	death
1.36	1.08e-08	GO:0045595	regulation of cell differentiation
1.31	1.30e-08	GO:0050793	regulation of developmental process
1.35	1.30e-08	GO:0010628	positive regulation of gene expression
1.31	2.04e-08	GO:0051641	cellular localization
1.38	2.10e-08	GO:0008219	cell death
1.28	2.43e-08	GO:0009056	catabolic process
1.35	3.23e-08	GO:0048699	generation of neurons
1.34	4.23e-08	GO:0016310	phosphorylation
1.32	4.30e-08	GO:0042127	regulation of cell proliferation
1.26	5.03e-08	GO:0031325	positive regulation of cellular metabolic process
1.34	8.95e-08	GO:0007049	cell cycle
1.33	1.05e-07	GO:0022008	neurogenesis
1.44	1.21e-07	GO:0060548	negative regulation of cell death
1.42	1.22e-07	GO:0072358	cardiovascular system development
1.42	1.22e-07	GO:0072359	circulatory system development
1.34	1.53e-07	GO:0051254	positive regulation of RNA metabolic process
1.57	1.72e-07	GO:0007264	small GTPase mediated signal transduction
1.44	1.98e-07	GO:0051726	regulation of cell cycle
1.34	2.16e-07	GO:0045893	positive regulation of transcription, DNA-dependent
1.29	2.52e-07	GO:0032879	regulation of localization
1.33	3.04e-07	GO:0044093	positive regulation of molecular function
1.52	3.19e-07	GO:0035295	tube development
1.38	3.63e-07	GO:0046907	intracellular transport
1.44	3.78e-07	GO:0043066	negative regulation of apoptosis
1.30	4.19e-07	GO:0032268	regulation of cellular protein metabolic process
1.45	4.19e-07	GO:0048598	embryonic morphogenesis
1.43	5.03e-07	GO:0043069	negative regulation of programmed cell death
1.28	5.98e-07	GO:0051246	regulation of protein metabolic process
1.50	6.91e-07	GO:0051130	positive regulation of cellular component organization
1.51	7.53e-07	GO:0032535	regulation of cellular component size
1.53	8.28e-07	GO:0001701	in utero embryonic development
1.31	8.82e-07	GO:0048468	cell development
1.45	9.88e-07	GO:0032583	regulation of gene-specific transcription
1.47	1.05e-06	GO:0090066	regulation of anatomical structure size
1.45	1.30e-06	GO:0060429	epithelium development
1.69	1.57e-06	GO:0051493	regulation of cytoskeleton organization
1.49	1.59e-06	GO:0010551	regulation of gene-specific transcription from RNA polymerase II promoter
1.61	2.63e-06	GO:0046578	regulation of Ras protein signal transduction
1.47	3.36e-06	GO:0007167	enzyme linked receptor protein signaling pathway
1.53	3.70e-06	GO:0007507	heart development
1.30	3.87e-06	GO:0022607	cellular component assembly
1.36	4.04e-06	GO:0016192	vesicle-mediated transport
1.28	4.26e-06	GO:0044085	cellular component biogenesis
1.39	4.90e-06	GO:0010942	positive regulation of cell death
1.27	5.45e-06	GO:0044248	cellular catabolic process
1.40	6.02e-06	GO:0006753	nucleoside phosphate metabolic process
1.40	6.02e-06	GO:0009117	nucleotide metabolic process
1.56	6.75e-06	GO:0051056	regulation of small GTPase mediated signal transduction
1.36	7.39e-06	GO:0071844	cellular component assembly at cellular level
1.45	7.44e-06	GO:0048729	tissue morphogenesis
1.38	8.64e-06	GO:0055086	nucleobase, nucleoside and nucleotide metabolic process
1.44	8.66e-06	GO:0006066	alcohol metabolic process
1.29	8.85e-06	GO:0010557	positive regulation of macromolecule biosynthetic process
1.27	8.89e-06	GO:0009891	positive regulation of biosynthetic process
1.28	9.37e-06	GO:0031328	positive regulation of cellular biosynthetic process
1.34	1.10e-05	GO:0009887	organ morphogenesis
1.43	1.12e-05	GO:0060284	regulation of cell development
1.29	1.13e-05	GO:0051649	establishment of localization in cell
1.37	1.21e-05	GO:0048646	anatomical structure formation involved in morphogenesis
1.38	1.22e-05	GO:0043068	positive regulation of programmed cell death
1.32	1.28e-05	GO:0006468	protein phosphorylation
1.38	1.52e-05	GO:0043065	positive regulation of apoptosis
1.33	1.62e-05	GO:0019220	regulation of phosphate metabolic process
1.33	1.62e-05	GO:0051174	regulation of phosphorus metabolic process
1.33	1.77e-05	GO:0033554	cellular response to stress
1.50	2.02e-05	GO:0002009	morphogenesis of an epithelium
1.47	2.06e-05	GO:0051098	regulation of binding
1.41	2.20e-05	GO:0051338	regulation of transferase activity
1.30	2.59e-05	GO:0048584	positive regulation of response to stimulus
1.43	3.40e-05	GO:0044262	cellular carbohydrate metabolic process
1.41	4.32e-05	GO:0043549	regulation of kinase activity
1.50	4.35e-05	GO:0009199	ribonucleoside triphosphate metabolic process
1.33	4.36e-05	GO:0042325	regulation of phosphorylation
1.49	4.42e-05	GO:0009141	nucleoside triphosphate metabolic process
1.33	4.56e-05	GO:0046483	heterocycle metabolic process
1.58	5.06e-05	GO:0032582	negative regulation of gene-specific transcription
1.64	5.61e-05	GO:0010553	negative regulation of gene-specific transcription from RNA polymerase II promoter
1.93	7.07e-05	GO:0007015	actin filament organization
1.37	7.24e-05	GO:0005975	carbohydrate metabolic process
1.27	9.06e-05	GO:0042592	homeostatic process
1.54	9.11e-05	GO:0051129	negative regulation of cellular component organization
1.49	1.00e-04	GO:0009205	purine ribonucleoside triphosphate metabolic process
1.36	1.00e-04	GO:0044282	small molecule catabolic process
1.44	1.08e-04	GO:0001944	vasculature development
1.40	1.12e-04	GO:0045597	positive regulation of cell differentiation
1.46	1.31e-04	GO:0001568	blood vessel development
1.31	1.35e-04	GO:0043085	positive regulation of catalytic activity
1.39	1.45e-04	GO:0040008	regulation of growth
1.46	1.47e-04	GO:0009150	purine ribonucleotide metabolic process
1.39	1.80e-04	GO:0072521	purine-containing compound metabolic process
1.46	2.08e-04	GO:0012502	induction of programmed cell death
1.44	2.17e-04	GO:0045596	negative regulation of cell differentiation
1.45	2.35e-04	GO:0009259	ribonucleotide metabolic process
1.60	2.38e-04	GO:0005996	monosaccharide metabolic process
1.32	2.64e-04	GO:0001932	regulation of protein phosphorylation
1.40	2.77e-04	GO:0045859	regulation of protein kinase activity
1.47	2.82e-04	GO:0009144	purine nucleoside triphosphate metabolic process
1.46	3.08e-04	GO:0006917	induction of apoptosis
1.33	3.48e-04	GO:0051094	positive regulation of developmental process
1.53	3.56e-04	GO:0044087	regulation of cellular component biogenesis
1.28	3.74e-04	GO:0031399	regulation of protein modification process
1.40	4.85e-04	GO:0006163	purine nucleotide metabolic process
1.42	5.06e-04	GO:0050767	regulation of neurogenesis
1.41	5.15e-04	GO:0051301	cell division
1.39	6.23e-04	GO:0051960	regulation of nervous system development
1.35	7.25e-04	GO:0080134	regulation of response to stress
1.31	7.63e-04	GO:0045944	positive regulation of transcription from RNA polymerase II promoter
1.68	7.96e-04	GO:0006184	GTP catabolic process
1.34	8.12e-04	GO:0030030	cell projection organization
1.40	8.49e-04	GO:0007243	intracellular protein kinase cascade
1.40	8.49e-04	GO:0023014	signal transduction via phosphorylation event
1.27	8.99e-04	GO:0051049	regulation of transport
1.55	1.01e-03	GO:0007346	regulation of mitotic cell cycle
1.49	1.03e-03	GO:0009143	nucleoside triphosphate catabolic process
1.73	1.06e-03	GO:0031346	positive regulation of cell projection organization
1.50	1.08e-03	GO:0009203	ribonucleoside triphosphate catabolic process
1.35	1.09e-03	GO:0034613	cellular protein localization
1.41	1.17e-03	GO:0016568	chromatin modification
1.65	1.24e-03	GO:0046039	GTP metabolic process
1.71	1.55e-03	GO:0032318	regulation of Ras GTPase activity
1.27	1.61e-03	GO:0022414	reproductive process
1.49	1.64e-03	GO:0009207	purine ribonucleoside triphosphate catabolic process
1.65	1.69e-03	GO:0010638	positive regulation of organelle organization
1.27	1.71e-03	GO:0000003	reproduction
1.32	1.89e-03	GO:0051276	chromosome organization
1.48	1.96e-03	GO:0009146	purine nucleoside triphosphate catabolic process
1.34	2.00e-03	GO:0070727	cellular macromolecule localization
1.69	2.01e-03	GO:0032970	regulation of actin filament-based process
1.33	2.24e-03	GO:0009967	positive regulation of signal transduction
1.37	2.38e-03	GO:0010627	regulation of intracellular protein kinase cascade
1.70	2.44e-03	GO:0032956	regulation of actin cytoskeleton organization
1.62	2.48e-03	GO:0019318	hexose metabolic process
1.67	2.81e-03	GO:0006470	protein dephosphorylation
1.60	2.93e-03	GO:0006913	nucleocytoplasmic transport
1.37	3.00e-03	GO:0007389	pattern specification process
1.34	3.00e-03	GO:0061024	membrane organization
1.42	3.45e-03	GO:0018193	peptidyl-amino acid modification
1.63	3.81e-03	GO:0043087	regulation of GTPase activity
1.06	3.95e-03	GO:0065007	biological regulation
1.43	4.55e-03	GO:0003002	regionalization
1.66	5.27e-03	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway
1.66	5.27e-03	GO:0010639	negative regulation of organelle organization
1.60	5.31e-03	GO:0010720	positive regulation of cell development
1.38	5.32e-03	GO:0009894	regulation of catabolic process
1.46	5.44e-03	GO:0009261	ribonucleotide catabolic process
1.42	5.47e-03	GO:0001501	skeletal system development
1.34	5.57e-03	GO:0016044	cellular membrane organization
1.61	5.64e-03	GO:0033124	regulation of GTP catabolic process
1.36	5.68e-03	GO:0006325	chromatin organization
1.27	6.12e-03	GO:0007154	cell communication
1.43	6.44e-03	GO:0061061	muscle structure development
1.83	6.54e-03	GO:0008064	regulation of actin polymerization or depolymerization
1.46	6.87e-03	GO:0009154	purine ribonucleotide catabolic process
1.42	6.88e-03	GO:0031329	regulation of cellular catabolic process
1.84	6.95e-03	GO:0034330	cell junction organization
1.85	7.35e-03	GO:0051494	negative regulation of cytoskeleton organization
1.39	7.45e-03	GO:0070647	protein modification by small protein conjugation or removal
1.76	7.76e-03	GO:0032271	regulation of protein polymerization
1.29	8.59e-03	GO:0030182	neuron differentiation
1.57	8.77e-03	GO:0051169	nuclear transport
1.57	8.77e-03	GO:0060541	respiratory system development
1.43	9.12e-03	GO:0008361	regulation of cell size
1.43	9.12e-03	GO:0010608	posttranscriptional regulation of gene expression
1.63	9.67e-03	GO:0090092	regulation of transmembrane receptor protein serine/threonine kinase signaling pathway
1.41	9.88e-03	GO:0009166	nucleotide catabolic process
1.29	1.02e-02	GO:0023056	positive regulation of signaling
1.51	1.03e-02	GO:0016311	dephosphorylation
1.80	1.13e-02	GO:0030832	regulation of actin filament length
1.40	1.15e-02	GO:0048568	embryonic organ development
1.43	1.15e-02	GO:0006195	purine nucleotide catabolic process
1.59	1.20e-02	GO:0043254	regulation of protein complex assembly
1.59	1.34e-02	GO:0030323	respiratory tube development
1.31	1.36e-02	GO:0032504	multicellular organism reproduction
1.31	1.36e-02	GO:0048609	multicellular organismal reproductive process
1.29	1.48e-02	GO:0010647	positive regulation of cell communication
1.42	1.51e-02	GO:0072523	purine-containing compound catabolic process
1.86	1.54e-02	GO:0030833	regulation of actin filament polymerization
1.36	1.61e-02	GO:0006886	intracellular protein transport
1.39	1.63e-02	GO:0034655	nucleobase, nucleoside, nucleotide and nucleic acid catabolic process
1.39	1.63e-02	GO:0034656	nucleobase, nucleoside and nucleotide catabolic process
2.36	1.66e-02	GO:0051017	actin filament bundle assembly
1.88	1.70e-02	GO:0007179	transforming growth factor beta receptor signaling pathway
1.55	1.75e-02	GO:0030811	regulation of nucleotide catabolic process
1.55	1.75e-02	GO:0033121	regulation of purine nucleotide catabolic process
1.45	1.82e-02	GO:0048610	cellular process involved in reproduction
1.64	1.83e-02	GO:0016331	morphogenesis of embryonic epithelium
1.24	1.91e-02	GO:0055085	transmembrane transport
1.33	1.92e-02	GO:0051093	negative regulation of developmental process
1.97	1.95e-02	GO:0031333	negative regulation of protein complex assembly
1.68	2.21e-02	GO:0008624	induction of apoptosis by extracellular signals
1.30	2.67e-02	GO:0032989	cellular component morphogenesis
1.41	3.44e-02	GO:0048514	blood vessel morphogenesis
1.57	3.47e-02	GO:0030324	lung development
1.91	3.69e-02	GO:0001889	liver development
1.77	3.75e-02	GO:0002755	MyD88-dependent toll-like receptor signaling pathway
1.50	4.02e-02	GO:0080135	regulation of cellular response to stress
1.38	4.05e-02	GO:0051347	positive regulation of transferase activity
1.45	4.11e-02	GO:0031344	regulation of cell projection organization
1.33	4.16e-02	GO:0008285	negative regulation of cell proliferation
1.35	4.26e-02	GO:0003006	developmental process involved in reproduction
1.72	4.32e-02	GO:0009953	dorsal/ventral pattern formation
1.41	4.33e-02	GO:0032880	regulation of protein localization
1.25	4.42e-02	GO:0070887	cellular response to chemical stimulus
1.05	4.49e-02	GO:0050789	regulation of biological process
1.68	4.61e-02	GO:0071496	cellular response to external stimulus

Gene overrepresentation in compartment category:

Enrichment	P-value	GO Accession	GO Term
1.24	1.09e-141	GO:0005622	intracellular
1.24	8.65e-135	GO:0044424	intracellular part
1.24	2.73e-100	GO:0043226	organelle
1.27	8.67e-100	GO:0005737	cytoplasm
1.24	2.34e-99	GO:0043229	intracellular organelle
1.26	2.45e-93	GO:0043227	membrane-bounded organelle
1.26	7.01e-92	GO:0043231	intracellular membrane-bounded organelle
1.28	2.07e-59	GO:0044444	cytoplasmic part
1.28	8.88e-53	GO:0005634	nucleus
1.09	2.33e-46	GO:0005623	cell
1.09	2.33e-46	GO:0044464	cell part
1.28	1.37e-39	GO:0044422	organelle part
1.28	1.88e-39	GO:0044446	intracellular organelle part
1.31	1.19e-30	GO:0043234	protein complex
1.42	1.84e-27	GO:0005829	cytosol
1.27	2.17e-27	GO:0032991	macromolecular complex
1.36	1.81e-24	GO:0044428	nuclear part
1.33	1.47e-19	GO:0043233	organelle lumen
1.33	2.26e-19	GO:0070013	intracellular organelle lumen
1.33	3.74e-19	GO:0031974	membrane-enclosed lumen
1.35	7.17e-19	GO:0031981	nuclear lumen
1.41	2.55e-17	GO:0005654	nucleoplasm
1.23	3.35e-14	GO:0043228	non-membrane-bounded organelle
1.23	3.35e-14	GO:0043232	intracellular non-membrane-bounded organelle
1.30	8.29e-14	GO:0005856	cytoskeleton
1.44	6.69e-13	GO:0044451	nucleoplasm part
1.38	2.15e-11	GO:0012505	endomembrane system
1.31	3.86e-11	GO:0000267	cell fraction
1.30	1.22e-09	GO:0042995	cell projection
1.32	2.64e-09	GO:0044430	cytoskeletal part
1.51	7.89e-09	GO:0005625	soluble fraction
1.31	9.68e-09	GO:0005794	Golgi apparatus
1.26	3.48e-08	GO:0031090	organelle membrane
1.30	5.45e-08	GO:0005626	insoluble fraction
1.33	7.88e-08	GO:0031982	vesicle
1.23	1.96e-07	GO:0005739	mitochondrion
1.42	2.92e-07	GO:0005768	endosome
1.50	4.97e-07	GO:0005667	transcription factor complex
1.33	5.16e-07	GO:0031410	cytoplasmic vesicle
1.58	1.30e-06	GO:0016323	basolateral plasma membrane
1.65	1.88e-06	GO:0031252	cell leading edge
1.35	4.03e-06	GO:0015630	microtubule cytoskeleton
1.12	1.05e-05	GO:0071944	cell periphery
1.26	1.99e-05	GO:0005624	membrane fraction
1.48	3.19e-05	GO:0005874	microtubule
1.45	3.31e-05	GO:0048471	perinuclear region of cytoplasm
1.17	5.52e-05	GO:0044459	plasma membrane part
1.56	7.19e-05	GO:0005635	nuclear envelope
1.32	8.01e-05	GO:0031988	membrane-bounded vesicle
1.97	1.68e-04	GO:0034399	nuclear periphery
1.32	2.18e-04	GO:0016023	cytoplasmic membrane-bounded vesicle
1.11	2.27e-04	GO:0005886	plasma membrane
1.60	2.66e-04	GO:0005938	cell cortex
1.30	2.84e-04	GO:0043005	neuron projection
1.28	3.19e-04	GO:0031967	organelle envelope
2.05	3.20e-04	GO:0016363	nuclear matrix
1.42	4.33e-04	GO:0015629	actin cytoskeleton
1.27	5.91e-04	GO:0031975	envelope
1.21	7.28e-04	GO:0005783	endoplasmic reticulum
1.53	1.09e-03	GO:0030135	coated vesicle
1.56	1.57e-03	GO:0030136	clathrin-coated vesicle
1.39	1.64e-03	GO:0044431	Golgi apparatus part
1.56	6.20e-03	GO:0005912	adherens junction
1.69	7.94e-03	GO:0044448	cell cortex part
1.23	1.64e-02	GO:0030054	cell junction
1.63	2.80e-02	GO:0009898	internal side of plasma membrane
1.49	2.99e-02	GO:0070161	anchoring junction
1.30	4.27e-02	GO:0044297	cell body
1.25	4.68e-02	GO:0045202	synapse

Gene overrepresentation in function category:

Enrichment	P-value	GO Accession	GO Term
1.20	2.15e-93	GO:0005488	binding
1.31	3.41e-74	GO:0005515	protein binding
1.17	1.55e-18	GO:0003824	catalytic activity
1.25	6.52e-18	GO:0003676	nucleic acid binding
1.26	5.93e-15	GO:0000166	nucleotide binding
1.19	1.29e-14	GO:0043167	ion binding
1.19	1.60e-14	GO:0043169	cation binding
1.19	3.31e-14	GO:0046872	metal ion binding
1.51	3.77e-13	GO:0008092	cytoskeletal protein binding
1.31	5.64e-13	GO:0008270	zinc ion binding
1.39	1.01e-12	GO:0019899	enzyme binding
1.27	8.78e-12	GO:0046914	transition metal ion binding
1.47	5.41e-11	GO:0019904	protein domain specific binding
1.38	1.28e-10	GO:0042802	identical protein binding
1.24	1.96e-10	GO:0035639	purine ribonucleoside triphosphate binding
1.24	3.03e-10	GO:0032553	ribonucleotide binding
1.24	3.33e-10	GO:0017076	purine nucleotide binding
1.24	3.85e-10	GO:0032555	purine ribonucleotide binding
1.24	4.46e-10	GO:0003677	DNA binding
1.24	1.55e-09	GO:0016740	transferase activity
1.33	5.20e-08	GO:0016301	kinase activity
1.47	5.87e-08	GO:0030695	GTPase regulator activity
1.30	8.63e-08	GO:0030528	transcription regulator activity
1.30	8.82e-08	GO:0016772	transferase activity, transferring phosphorus-containing groups
1.46	1.13e-07	GO:0060589	nucleoside-triphosphatase regulator activity
1.53	1.99e-07	GO:0019900	kinase binding
1.34	3.41e-07	GO:0016773	phosphotransferase activity, alcohol group as acceptor
1.30	1.08e-06	GO:0030234	enzyme regulator activity
1.50	1.83e-06	GO:0003779	actin binding
1.32	2.16e-06	GO:0046983	protein dimerization activity
1.56	2.29e-06	GO:0000989	transcription factor binding transcription factor activity
1.55	2.87e-06	GO:0000988	protein binding transcription factor activity
1.54	3.54e-06	GO:0016879	ligase activity, forming carbon-nitrogen bonds
1.55	3.60e-06	GO:0003712	transcription cofactor activity
1.30	4.42e-06	GO:0001071	nucleic acid binding transcription factor activity
1.30	4.42e-06	GO:0003700	sequence-specific DNA binding transcription factor activity
1.21	5.95e-06	GO:0030554	adenyl nucleotide binding
1.47	6.26e-06	GO:0008134	transcription factor binding
1.21	6.82e-06	GO:0032559	adenyl ribonucleotide binding
1.21	1.22e-05	GO:0005524	ATP binding
1.56	1.98e-05	GO:0005096	GTPase activator activity
1.51	2.19e-05	GO:0019901	protein kinase binding
1.54	2.46e-05	GO:0016881	acid-amino acid ligase activity
1.29	3.59e-05	GO:0003723	RNA binding
1.49	6.09e-05	GO:0005083	small GTPase regulator activity
1.42	6.70e-05	GO:0016563	transcription activator activity
1.53	7.63e-05	GO:0000975	regulatory region DNA binding
1.53	7.63e-05	GO:0001067	regulatory region nucleic acid binding
1.53	7.63e-05	GO:0044212	transcription regulatory region DNA binding
1.23	1.04e-04	GO:0005215	transporter activity
1.54	1.09e-04	GO:0010843	promoter binding
1.54	1.09e-04	GO:0019787	small conjugating protein ligase activity
1.34	1.63e-04	GO:0042803	protein homodimerization activity
1.37	1.69e-04	GO:0016874	ligase activity
1.25	2.03e-04	GO:0022892	substrate-specific transporter activity
1.42	2.43e-04	GO:0016564	transcription repressor activity
1.28	3.56e-04	GO:0043565	sequence-specific DNA binding
1.58	6.58e-04	GO:0003924	GTPase activity
1.40	1.01e-03	GO:0008047	enzyme activator activity
1.37	1.02e-03	GO:0032403	protein complex binding
1.52	1.13e-03	GO:0004842	ubiquitin-protein ligase activity
1.29	1.15e-03	GO:0004672	protein kinase activity
1.34	1.73e-03	GO:0008289	lipid binding
1.58	1.85e-03	GO:0003713	transcription coactivator activity
1.64	1.94e-03	GO:0015631	tubulin binding
1.33	2.07e-03	GO:0004674	protein serine/threonine kinase activity
1.37	2.24e-03	GO:0005525	GTP binding
1.64	4.44e-03	GO:0035091	phosphatidylinositol binding
1.41	9.29e-03	GO:0016791	phosphatase activity
1.71	1.06e-02	GO:0008017	microtubule binding
1.22	1.41e-02	GO:0022891	substrate-specific transmembrane transporter activity
1.46	1.45e-02	GO:0005543	phospholipid binding
1.12	1.88e-02	GO:0016787	hydrolase activity
1.32	2.09e-02	GO:0019001	guanyl nucleotide binding
1.32	2.09e-02	GO:0032561	guanyl ribonucleotide binding
1.34	2.35e-02	GO:0042578	phosphoric ester hydrolase activity
1.27	2.86e-02	GO:0008324	cation transmembrane transporter activity
2.73	3.06e-02	GO:0070412	R-SMAD binding
1.84	3.29e-02	GO:0046332	SMAD binding
1.20	3.48e-02	GO:0022857	transmembrane transporter activity
1.54	3.71e-02	GO:0005516	calmodulin binding