Motif ID: LHX3,4.p2

Z-value: 1.060


Transcription factors associated with LHX3,4.p2:

Gene SymbolEntrez IDGene Name
Lhx3 16871 LIM homeobox protein 3
Lhx4 16872 LIM homeobox protein 4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Lhx3chr2_-_260620080.215.2e-03Click!
Lhx4chr1_-_157589156-0.082.7e-01Click!


Activity profile for motif LHX3,4.p2.

activity profile for motif LHX3,4.p2


Sorted Z-values histogram for motif LHX3,4.p2

Sorted Z-values for motif LHX3,4.p2



Network of associatons between targets according to the STRING database.



First level regulatory network of LHX3,4.p2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_-_48571942 54.778 Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr17_-_48572043 49.113 NM_009694
 Apobec2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr6_+_124254668 16.095 NM_001170395
NM_053094
 Cd163

CD163 antigen

chr6_+_4483741 12.999 Col1a2
collagen, type I, alpha 2
chr11_+_67051128 11.021 Myh4
myosin, heavy polypeptide 4, skeletal muscle
chr11_+_67611772 10.130 NM_001013013
 Dhrs7c
dehydrogenase/reductase (SDR family) member 7C
chr3_+_101949321 9.334 Casq2
calsequestrin 2
chr7_-_52359079 9.155 NM_010189
 Fcgrt
Fc receptor, IgG, alpha chain transporter
chr5_-_17394564 9.042 Cd36
CD36 antigen
chr10_-_61960613 8.638 Srgn
serglycin
chr17_-_74242984 8.504 Xdh
xanthine dehydrogenase
chr6_-_3349415 8.373 Samd9l
sterile alpha motif domain containing 9-like
chr5_-_17394776 8.025 NM_001159558
 Cd36
CD36 antigen
chr17_-_34999068 7.901 Cfb
complement factor B
chr6_+_145882641 7.895 NM_010656
 Sspn
sarcospan
chr1_+_19093102 7.836 NM_153154
 Tcfap2d
transcription factor AP-2, delta
chr2_+_69508174 7.786 NM_001081087
 Kbtbd10
kelch repeat and BTB (POZ) domain containing 10
chr17_-_34999458 7.761 NM_001142706
NM_008198
 Cfb

complement factor B

chr16_-_11220854 7.578 Gspt1
G1 to S phase transition 1
chr10_+_96945057 7.536 Dcn
decorin

Gene Ontology Analysis

Gene overrepresentation in process category:

Showing 1 to 20 of 24 entries
Enrichment   P-value GO Accession GO Term
6.65 1.04e-02 GO:0051897 positive regulation of protein kinase B signaling cascade
5.54 1.85e-02 GO:0051149 positive regulation of muscle cell differentiation
3.07 2.90e-02 GO:0042692 muscle cell differentiation
3.02 6.64e-04 GO:0048732 gland development
2.71 3.70e-03 GO:0061061 muscle structure development
2.12 6.31e-03 GO:0072358 cardiovascular system development
2.12 6.31e-03 GO:0072359 circulatory system development
2.07 9.66e-06 GO:0009888 tissue development
1.97 1.32e-02 GO:0009887 organ morphogenesis
1.83 2.41e-02 GO:0048584 positive regulation of response to stimulus
1.81 6.81e-03 GO:0042127 regulation of cell proliferation
1.77 2.90e-02 GO:2000026 regulation of multicellular organismal development
1.73 1.40e-02 GO:0050793 regulation of developmental process
1.67 2.64e-03 GO:0009653 anatomical structure morphogenesis
1.66 1.15e-04 GO:0048513 organ development
1.54 1.07e-02 GO:0065008 regulation of biological quality
1.51 8.02e-04 GO:0048731 system development
1.49 2.05e-03 GO:0048519 negative regulation of biological process
1.48 4.48e-04 GO:0048856 anatomical structure development
1.46 2.88e-02 GO:0048523 negative regulation of cellular process

Gene overrepresentation in compartment category:

Showing 1 to 3 of 3 entries
Enrichment   P-value GO Accession GO Term
1.90 3.95e-05 GO:0044421 extracellular region part
1.89 1.85e-03 GO:0005615 extracellular space
1.55 7.88e-04 GO:0005576 extracellular region

Gene overrepresentation in function category:

Showing 1 to 5 of 5 entries
Enrichment   P-value GO Accession GO Term
10.16 3.27e-02 GO:0005159 insulin-like growth factor receptor binding
1.93 3.49e-03 GO:0043565 sequence-specific DNA binding
1.83 5.29e-03 GO:0001071 nucleic acid binding transcription factor activity
1.83 5.29e-03 GO:0003700 sequence-specific DNA binding transcription factor activity
1.75 5.26e-03 GO:0030528 transcription regulator activity